| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the clindamycin-2219 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAK1 | AP2 associated kinase 1 |
| ABCB8 | ATP-binding cassette, sub-family B (MDR/TAP), member 8 |
| ADGRB2 | adhesion G protein-coupled receptor B2 |
| ADPRM | ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent |
| AKAP8L | A kinase (PRKA) anchor protein 8-like |
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 |
| ALOXE3 | arachidonate lipoxygenase 3 |
| APOE | apolipoprotein E |
| ARAP1 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) |
| ASIC3 | acid sensing (proton gated) ion channel 3 |
| B9D1 | B9 protein domain 1 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B |
| C19ORF66 | chromosome 19 open reading frame 66 |
| C1ORF21 | chromosome 1 open reading frame 21 |
| CAMK2B | calcium/calmodulin-dependent protein kinase II beta |
| CAMK4 | calcium/calmodulin-dependent protein kinase IV |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase |
| CFLAR | CASP8 and FADD-like apoptosis regulator |
| CLCN1 | chloride channel, voltage-sensitive 1 |
| CLTC | clathrin, heavy chain (Hc) |
| COL14A1 | collagen, type XIV, alpha 1 |
| CTBP2 | C-terminal binding protein 2 |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DOK1 | docking protein 1, 62kDa (downstream of tyrosine kinase 1) |
| EDNRA | endothelin receptor type A |
| ERCC4 | excision repair cross-complementation group 4 |
| FABP6 | fatty acid binding protein 6, ileal |
| FAM76A | family with sequence similarity 76, member A |
| FHL1 | four and a half LIM domains 1 |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GNL3L | guanine nucleotide binding protein-like 3 (nucleolar)-like |
| GPRIN2 | G protein regulated inducer of neurite outgrowth 2 |
| GREB1 | growth regulation by estrogen in breast cancer 1 |
| GRK5 | G protein-coupled receptor kinase 5 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 |
| HFE | hemochromatosis |
| HP1BP3 | heterochromatin protein 1, binding protein 3 |
| IL1RN | interleukin 1 receptor antagonist |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) |
| KANK1 | KN motif and ankyrin repeat domains 1 |
| KLF12 | Kruppel-like factor 12 |
| LAMP1 | lysosomal-associated membrane protein 1 |
| LRP4 | low density lipoprotein receptor-related protein 4 |
| MALL | mal, T-cell differentiation protein-like |
| MED18 | mediator complex subunit 18 |
| MGEA5 | meningioma expressed antigen 5 (hyaluronidase) |
| MKL1 | megakaryoblastic leukemia (translocation) 1 |
| NF2 | neurofibromin 2 (merlin) |
| NPC1 | Niemann-Pick disease, type C1 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 |
| NRG1 | neuregulin 1 |
| OCLM | oculomedin |
| PARD6B | par-6 family cell polarity regulator beta |
| PCDH12 | protocadherin 12 |
| PLCD1 | phospholipase C, delta 1 |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PLXNC1 | plexin C1 |
| PPP1R17 | protein phosphatase 1, regulatory subunit 17 |
| PQBP1 | polyglutamine binding protein 1 |
| PRDX2 | peroxiredoxin 2 |
| PRKCQ | protein kinase C, theta |
| PROSC | proline synthetase co-transcribed homolog (bacterial) |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
| PSMB2 | proteasome (prosome, macropain) subunit, beta type, 2 |
| PSMB9 | proteasome (prosome, macropain) subunit, beta type, 9 |
| PTPRCAP | protein tyrosine phosphatase, receptor type, C-associated protein |
| PVR | poliovirus receptor |
| RABGAP1 | RAB GTPase activating protein 1 |
| RAD52 | RAD52 homolog (S. cerevisiae) |
| RASSF2 | Ras association (RalGDS/AF-6) domain family member 2 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 |
| RB1 | retinoblastoma 1 |
| RCHY1 | ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) |
| RNGTT | RNA guanylyltransferase and 5'-phosphatase |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 |
| RSPH14 | radial spoke head 14 homolog (Chlamydomonas) |
| SEC24D | SEC24 family member D |
| SEMA7A | semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) |
| SLC24A1 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 |
| SORT1 | sortilin 1 |
| SULT4A1 | sulfotransferase family 4A, member 1 |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| SVEP1 | sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 |
| SYDE1 | synapse defective 1, Rho GTPase, homolog 1 (C. elegans) |
| TAOK1 | TAO kinase 1 |
| TLK1 | tousled-like kinase 1 |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
| TP53I11 | tumor protein p53 inducible protein 11 |
| UBQLN4 | ubiquilin 4 |
| WDFY3 | WD repeat and FYVE domain containing 3 |
| WDR55 | WD repeat domain 55 |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| YOD1 | YOD1 deubiquitinase |
| ZMYND8 | zinc finger, MYND-type containing 8 |
| ZNF235 | zinc finger protein 235 |
| ZNF652 | zinc finger protein 652 |
| ZSWIM1 | zinc finger, SWIM-type containing 1 |
| Symbol | Name |
|---|---|
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| ADTRP | androgen-dependent TFPI-regulating protein |
| ANKRD7 | ankyrin repeat domain 7 |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
| APBB3 | amyloid beta (A4) precursor protein-binding, family B, member 3 |
| APOLD1 | apolipoprotein L domain containing 1 |
| ARHGAP4 | Rho GTPase activating protein 4 |
| ARHGEF6 | Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 |
| B3GALT4 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 |
| B4GALT2 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 |
| C14ORF79 | chromosome 14 open reading frame 79 |
| CALCOCO1 | calcium binding and coiled-coil domain 1 |
| CBX4 | chromobox homolog 4 |
| CCDC134 | coiled-coil domain containing 134 |
| CCDC88C | coiled-coil domain containing 88C |
| CD34 | CD34 molecule |
| CD3D | CD3d molecule, delta (CD3-TCR complex) |
| CD80 | CD80 molecule |
| CEL | carboxyl ester lipase |
| CIC | capicua transcriptional repressor |
| CLCN2 | chloride channel, voltage-sensitive 2 |
| CRABP1 | cellular retinoic acid binding protein 1 |
| CRLF1 | cytokine receptor-like factor 1 |
| CSF1R | colony stimulating factor 1 receptor |
| CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 |
| DDX54 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 |
| DHX35 | DEAH (Asp-Glu-Ala-His) box polypeptide 35 |
| DTX2 | deltex 2, E3 ubiquitin ligase |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FADS2 | fatty acid desaturase 2 |
| FAM110B | family with sequence similarity 110, member B |
| FAM155A | family with sequence similarity 155, member A |
| FAM204A | family with sequence similarity 204, member A |
| FLJ22184 | |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GAMT | guanidinoacetate N-methyltransferase |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 |
| GPR21 | G protein-coupled receptor 21 |
| HIST1H4D | histone cluster 1, H4d |
| HSPA1L | heat shock 70kDa protein 1-like |
| IQSEC2 | IQ motif and Sec7 domain 2 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
| KDM8 | lysine (K)-specific demethylase 8 |
| KLHL21 | kelch-like family member 21 |
| KLHL25 | kelch-like family member 25 |
| KRT15 | keratin 15, type I |
| KRT6B | keratin 6B, type II |
| LYPD3 | LY6/PLAUR domain containing 3 |
| MMP15 | matrix metallopeptidase 15 (membrane-inserted) |
| MYOZ1 | myozenin 1 |
| NACA2 | nascent polypeptide-associated complex alpha subunit 2 |
| NOL12 | nucleolar protein 12 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 |
| NT5DC3 | 5'-nucleotidase domain containing 3 |
| OSGIN1 | oxidative stress induced growth inhibitor 1 |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PEX26 | peroxisomal biogenesis factor 26 |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PLA2G4C | phospholipase A2, group IVC (cytosolic, calcium-independent) |
| PLAC1 | placenta-specific 1 |
| POM121 | POM121 transmembrane nucleoporin |
| PRODH | proline dehydrogenase (oxidase) 1 |
| PRRG2 | proline rich Gla (G-carboxyglutamic acid) 2 |
| PTPRU | protein tyrosine phosphatase, receptor type, U |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RAB40C | RAB40C, member RAS oncogene family |
| RAB5B | RAB5B, member RAS oncogene family |
| RHBDD3 | rhomboid domain containing 3 |
| RNF208 | ring finger protein 208 |
| RNF39 | ring finger protein 39 |
| RPH3AL | rabphilin 3A-like (without C2 domains) |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| S100A9 | S100 calcium binding protein A9 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
| SLC46A3 | solute carrier family 46, member 3 |
| SLC9A3R2 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| STARD3 | StAR-related lipid transfer (START) domain containing 3 |
| TBC1D17 | TBC1 domain family, member 17 |
| TFF2 | trefoil factor 2 |
| TIGD6 | tigger transposable element derived 6 |
| TMEM8B | transmembrane protein 8B |
| TRDMT1 | tRNA aspartic acid methyltransferase 1 |
| TSPAN2 | tetraspanin 2 |
| USB1 | U6 snRNA biogenesis 1 |
| USP20 | ubiquitin specific peptidase 20 |
| VEGFB | vascular endothelial growth factor B |
| WFDC2 | WAP four-disulfide core domain 2 |
| XDH | xanthine dehydrogenase |
| XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 |
| XYLT2 | xylosyltransferase II |
| ZBTB33 | zinc finger and BTB domain containing 33 |
| ZNF329 | zinc finger protein 329 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF446 | zinc finger protein 446 |
