clindamycin-5815 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the clindamycin-5815 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM12 ADAM metallopeptidase domain 12
ADARB1 adenosine deaminase, RNA-specific, B1
ADRA1A adrenoceptor alpha 1A
AGFG1 ArfGAP with FG repeats 1
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
ARID1A AT rich interactive domain 1A (SWI-like)
ASIC3 acid sensing (proton gated) ion channel 3
BTF3P11 basic transcription factor 3 pseudogene 11
C5AR2 complement component 5a receptor 2
C8A complement component 8, alpha polypeptide
CCPG1 cell cycle progression 1
CDC14A cell division cycle 14A
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CDK17 cyclin-dependent kinase 17
CEMP1 cementum protein 1
CHMP6 charged multivesicular body protein 6
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CNGB3 cyclic nucleotide gated channel beta 3
CNIH3 cornichon family AMPA receptor auxiliary protein 3
CRELD1 cysteine-rich with EGF-like domains 1
CSPP1 centrosome and spindle pole associated protein 1
CTSF cathepsin F
DUSP9 dual specificity phosphatase 9
EPAS1 endothelial PAS domain protein 1
EPHX2 epoxide hydrolase 2, cytoplasmic
EVI5 ecotropic viral integration site 5
FGF18 fibroblast growth factor 18
FN1 fibronectin 1
FNDC3A fibronectin type III domain containing 3A
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2
GJA8 gap junction protein, alpha 8, 50kDa
GTDC1 glycosyltransferase-like domain containing 1
HIST1H3G histone cluster 1, H3g
HOXA4 homeobox A4
HOXC11 homeobox C11
IFT38 intraflagellar transport 38
IGL immunoglobulin lambda locus
INADL InaD-like (Drosophila)
IQCK IQ motif containing K
IRAK4 interleukin-1 receptor-associated kinase 4
JRK Jrk homolog (mouse)
KCTD13 potassium channel tetramerization domain containing 13
KIF1A kinesin family member 1A
KRIT1 KRIT1, ankyrin repeat containing
LPAR2 lysophosphatidic acid receptor 2
LYRM9 LYR motif containing 9
MAPT microtubule-associated protein tau
MBNL2 muscleblind-like splicing regulator 2
MCF2L MCF.2 cell line derived transforming sequence-like
MST1 macrophage stimulating 1
NCR2 natural cytotoxicity triggering receptor 2
NEK11 NIMA-related kinase 11
NF1 neurofibromin 1
NR4A2 nuclear receptor subfamily 4, group A, member 2
NRXN3 neurexin 3
PEX10 peroxisomal biogenesis factor 10
PHC1 polyhomeotic homolog 1 (Drosophila)
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PLEK pleckstrin
PPP5C protein phosphatase 5, catalytic subunit
PTPN21 protein tyrosine phosphatase, non-receptor type 21
QRSL1 glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1
QTRT1 queuine tRNA-ribosyltransferase 1
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RGS12 regulator of G-protein signaling 12
RPL7 ribosomal protein L7
RPRM reprimo, TP53 dependent G2 arrest mediator candidate
RPS3A ribosomal protein S3A
RUNX1 runt-related transcription factor 1
SALL2 spalt-like transcription factor 2
SENP5 SUMO1/sentrin specific peptidase 5
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
SGSM3 small G protein signaling modulator 3
SH3BP2 SH3-domain binding protein 2
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SMYD2 SET and MYND domain containing 2
SOGA1 suppressor of glucose, autophagy associated 1
SOS2 son of sevenless homolog 2 (Drosophila)
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding)
SPON1 spondin 1, extracellular matrix protein
STC1 stanniocalcin 1
TAGLN3 transgelin 3
TINAGL1 tubulointerstitial nephritis antigen-like 1
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TNFSF18 tumor necrosis factor (ligand) superfamily, member 18
TNIK TRAF2 and NCK interacting kinase
TPD52 tumor protein D52
TPMT thiopurine S-methyltransferase
TRIM23 tripartite motif containing 23
TRIM62 tripartite motif containing 62
TSKU tsukushi, small leucine rich proteoglycan
TUBA3C tubulin, alpha 3c
TUBGCP3 tubulin, gamma complex associated protein 3
TUBGCP5 tubulin, gamma complex associated protein 5
UBTD1 ubiquitin domain containing 1
ZNF407 zinc finger protein 407
ZNF552 zinc finger protein 552

decreased expression

Symbol Name
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3
AP3M2 adaptor-related protein complex 3, mu 2 subunit
BDH2 3-hydroxybutyrate dehydrogenase, type 2
BNC2 basonuclin 2
BTF3P12 basic transcription factor 3 pseudogene 12
C11ORF80 chromosome 11 open reading frame 80
C17ORF70 chromosome 17 open reading frame 70
C1ORF56 chromosome 1 open reading frame 56
CAPN5 calpain 5
CDADC1 cytidine and dCMP deaminase domain containing 1
CINP cyclin-dependent kinase 2 interacting protein
CIR1 corepressor interacting with RBPJ, 1
COBL cordon-bleu WH2 repeat protein
CORT cortistatin
CWC25 CWC25 spliceosome-associated protein homolog (S. cerevisiae)
CXCL3 chemokine (C-X-C motif) ligand 3
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DCAF10 DDB1 and CUL4 associated factor 10
DDIT3 DNA-damage-inducible transcript 3
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DNAL4 dynein, axonemal, light chain 4
DOCK1 dedicator of cytokinesis 1
EFCAB2 EF-hand calcium binding domain 2
ELOVL4 ELOVL fatty acid elongase 4
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6
GINS4 GINS complex subunit 4 (Sld5 homolog)
GLI3 GLI family zinc finger 3
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GUSBP3 glucuronidase, beta pseudogene 3
HDHD3 haloacid dehalogenase-like hydrolase domain containing 3
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HIST1H2AE histone cluster 1, H2ae
HIST1H2AI histone cluster 1, H2ai
HIST1H2BJ histone cluster 1, H2bj
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HYAL3 hyaluronoglucosaminidase 3
IPP intracisternal A particle-promoted polypeptide
IRF9 interferon regulatory factor 9
KCTD7 potassium channel tetramerization domain containing 7
KIRREL kin of IRRE like (Drosophila)
LMBR1L limb development membrane protein 1-like
LOC100286895 cell division cycle 27 homolog pseudogene
LRFN3 leucine rich repeat and fibronectin type III domain containing 3
LRRK1 leucine-rich repeat kinase 1
MAST3 microtubule associated serine/threonine kinase 3
MGAT4A mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
MNX1 motor neuron and pancreas homeobox 1
MT1M metallothionein 1M
MUC3B mucin 3B, cell surface associated
NRSN2 neurensin 2
NTHL1 nth endonuclease III-like 1 (E. coli)
PACS1 phosphofurin acidic cluster sorting protein 1
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PAK6 p21 protein (Cdc42/Rac)-activated kinase 6
PAN2 PAN2 poly(A) specific ribonuclease subunit
PDXDC1 pyridoxal-dependent decarboxylase domain containing 1
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLCD1 phospholipase C, delta 1
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRR15L proline rich 15-like
PRR3 proline rich 3
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
RAI2 retinoic acid induced 2
RCL1 RNA terminal phosphate cyclase-like 1
RECQL4 RecQ protein-like 4
RGS19 regulator of G-protein signaling 19
RNF25 ring finger protein 25
SH3TC2 SH3 domain and tetratricopeptide repeats 2
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SNHG3 small nucleolar RNA host gene 3
SPAG4 sperm associated antigen 4
STAG3 stromal antigen 3
STEAP4 STEAP family member 4
SUOX sulfite oxidase
TNK1 tyrosine kinase, non-receptor, 1
TNNI3 troponin I type 3 (cardiac)
TNS2 tensin 2
TOR4A torsin family 4, member A
TRAPPC6A trafficking protein particle complex 6A
UNKL unkempt family zinc finger-like
USP27X ubiquitin specific peptidase 27, X-linked
USP32 ubiquitin specific peptidase 32
WDR37 WD repeat domain 37
WDR76 WD repeat domain 76
XAB2 XPA binding protein 2
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZNF273 zinc finger protein 273
ZNF426 zinc finger protein 426
ZNF430 zinc finger protein 430
ZNF652 zinc finger protein 652
ZNF767P zinc finger family member 767, pseudogene
ZNF84 zinc finger protein 84
ZNF91 zinc finger protein 91