clindamycin-7172 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the clindamycin-7172 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
APOC1 apolipoprotein C-I
AQP3 aquaporin 3 (Gill blood group)
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
ARHGAP35 Rho GTPase activating protein 35
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
BAG4 BCL2-associated athanogene 4
BCL2L11 BCL2-like 11 (apoptosis facilitator)
CACFD1 calcium channel flower domain containing 1
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CADM3 cell adhesion molecule 3
CARD8 caspase recruitment domain family, member 8
CASP2 caspase 2, apoptosis-related cysteine peptidase
CASP3 caspase 3, apoptosis-related cysteine peptidase
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCDC134 coiled-coil domain containing 134
CCR7 chemokine (C-C motif) receptor 7
CD44 CD44 molecule (Indian blood group)
CD6 CD6 molecule
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CFLAR CASP8 and FADD-like apoptosis regulator
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CPNE7 copine VII
CRELD1 cysteine-rich with EGF-like domains 1
CRYGD crystallin, gamma D
CST6 cystatin E/M
CXCR4 chemokine (C-X-C motif) receptor 4
CYP2W1 cytochrome P450, family 2, subfamily W, polypeptide 1
DBN1 drebrin 1
DCTN1 dynactin 1
DENND4A DENN/MADD domain containing 4A
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DPYSL4 dihydropyrimidinase-like 4
EDRF1 erythroid differentiation regulatory factor 1
FANCE Fanconi anemia, complementation group E
FLT3LG fms-related tyrosine kinase 3 ligand
GBP1 guanylate binding protein 1, interferon-inducible
GLRX glutaredoxin (thioltransferase)
GRB10 growth factor receptor-bound protein 10
GSTTP1 glutathione S-transferase theta pseudogene 1
HFE hemochromatosis
HIST1H4F histone cluster 1, H4f
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HNF4A hepatocyte nuclear factor 4, alpha
IBA57 IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae)
IGHMBP2 immunoglobulin mu binding protein 2
IL1RN interleukin 1 receptor antagonist
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1
LEFTY2 left-right determination factor 2
LOC257152 uncharacterized LOC257152
LONRF3 LON peptidase N-terminal domain and ring finger 3
LY6G6C lymphocyte antigen 6 complex, locus G6C
MANEA mannosidase, endo-alpha
MAPK11 mitogen-activated protein kinase 11
MBD3 methyl-CpG binding domain protein 3
MBNL2 muscleblind-like splicing regulator 2
MEF2D myocyte enhancer factor 2D
MERTK MER proto-oncogene, tyrosine kinase
MIIP migration and invasion inhibitory protein
MPPE1 metallophosphoesterase 1
NNAT neuronatin
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
PACS1 phosphofurin acidic cluster sorting protein 1
PASK PAS domain containing serine/threonine kinase
PDE4A phosphodiesterase 4A, cAMP-specific
PHLDB1 pleckstrin homology-like domain, family B, member 1
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
POLL polymerase (DNA directed), lambda
PQBP1 polyglutamine binding protein 1
QKI QKI, KH domain containing, RNA binding
RCN1 reticulocalbin 1, EF-hand calcium binding domain
RGS12 regulator of G-protein signaling 12
RIN2 Ras and Rab interactor 2
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RPL7 ribosomal protein L7
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
RTEL1 regulator of telomere elongation helicase 1
SCARB1 scavenger receptor class B, member 1
SENP5 SUMO1/sentrin specific peptidase 5
SGSM3 small G protein signaling modulator 3
SKIL SKI-like proto-oncogene
SND1-IT1 SND1 intronic transcript 1
SNRK SNF related kinase
SPRR1A small proline-rich protein 1A
SRI sorcin
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila)
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TAS2R1 taste receptor, type 2, member 1
TGFB2 transforming growth factor, beta 2
THRA thyroid hormone receptor, alpha
TLE2 transducin-like enhancer of split 2
TRIM10 tripartite motif containing 10
TSGA10 testis specific, 10
UBOX5 U-box domain containing 5
VWA5A von Willebrand factor A domain containing 5A
WDR62 WD repeat domain 62
ZKSCAN3 zinc finger with KRAB and SCAN domains 3

decreased expression

Symbol Name
ABCB7 ATP-binding cassette, sub-family B (MDR/TAP), member 7
ABHD14A abhydrolase domain containing 14A
ABHD4 abhydrolase domain containing 4
AGBL5 ATP/GTP binding protein-like 5
AMBRA1 autophagy/beclin-1 regulator 1
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ARNTL2 aryl hydrocarbon receptor nuclear translocator-like 2
ATP13A2 ATPase type 13A2
BAHD1 bromo adjacent homology domain containing 1
BAK1 BCL2-antagonist/killer 1
C17ORF70 chromosome 17 open reading frame 70
CCDC88C coiled-coil domain containing 88C
CCDC94 coiled-coil domain containing 94
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
COPS7B COP9 signalosome subunit 7B
CTSK cathepsin K
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2
DSPP dentin sialophosphoprotein
DVL1 dishevelled segment polarity protein 1
FAM127B family with sequence similarity 127, member B
FBXL6 F-box and leucine-rich repeat protein 6
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FLVCR2 feline leukemia virus subgroup C cellular receptor family, member 2
FZD2 frizzled class receptor 2
FZD4 frizzled class receptor 4
GLCE glucuronic acid epimerase
GNA12 guanine nucleotide binding protein (G protein) alpha 12
GOLGA8B golgin A8 family, member B
GPATCH3 G patch domain containing 3
GPRC5C G protein-coupled receptor, class C, group 5, member C
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
LAMB1 laminin, beta 1
LOXL1 lysyl oxidase-like 1
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MAN2B1 mannosidase, alpha, class 2B, member 1
MAP1S microtubule-associated protein 1S
MAST3 microtubule associated serine/threonine kinase 3
METTL21B methyltransferase like 21B
MMP9 matrix metallopeptidase 9
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MUM1 melanoma associated antigen (mutated) 1
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
NECAB3 N-terminal EF-hand calcium binding protein 3
NUP62CL nucleoporin 62kDa C-terminal like
NUS1P3 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3
PARP16 poly (ADP-ribose) polymerase family, member 16
PCDHB3 protocadherin beta 3
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PDZRN3 PDZ domain containing ring finger 3
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PLD2 phospholipase D2
PLD3 phospholipase D family, member 3
PNPLA6 patatin-like phospholipase domain containing 6
PRKX protein kinase, X-linked
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAB4B RAB4B, member RAS oncogene family
RAB5B RAB5B, member RAS oncogene family
RAB8B RAB8B, member RAS oncogene family
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RNF25 ring finger protein 25
RNF31 ring finger protein 31
RNF41 ring finger protein 41, E3 ubiquitin protein ligase
RPL23AP7 ribosomal protein L23a pseudogene 7
SCN1B sodium channel, voltage gated, type I beta subunit
SETMAR SET domain and mariner transposase fusion gene
SIK1 salt-inducible kinase 1
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae)
SLC12A8 solute carrier family 12, member 8
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter)
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC26A6 solute carrier family 26 (anion exchanger), member 6
SOX3 SRY (sex determining region Y)-box 3
SPATA7 spermatogenesis associated 7
STK25 serine/threonine kinase 25
TESK1 testis-specific kinase 1
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast)
TLR5 toll-like receptor 5
TMC5 transmembrane channel-like 5
TP53BP1 tumor protein p53 binding protein 1
TRABD TraB domain containing
TRAF2 TNF receptor-associated factor 2
TRAIP TRAF interacting protein
TRIM25 tripartite motif containing 25
TRIM52 tripartite motif containing 52
TSPAN14 tetraspanin 14
TUBA3C tubulin, alpha 3c
URGCP upregulator of cell proliferation
VGF VGF nerve growth factor inducible
WDR19 WD repeat domain 19
WDR60 WD repeat domain 60
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZBTB48 zinc finger and BTB domain containing 48
ZBTB6 zinc finger and BTB domain containing 6
ZFP36 ZFP36 ring finger protein
ZNF354A zinc finger protein 354A
ZNF408 zinc finger protein 408
ZNF768 zinc finger protein 768