clinical Gene Set

Dataset Phosphosite Textmining Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

177 proteins co-occuring with the biological term clinical in abstracts of publications describing phosphosites from the Phosphosite Textmining Biological Term Annotations dataset.

Symbol Name
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACACA acetyl-CoA carboxylase alpha
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT1S1 AKT1 substrate 1 (proline-rich)
APP amyloid beta (A4) precursor protein
AQP5 aquaporin 5
AR androgen receptor
ATF4 activating transcription factor 4
ATM ATM serine/threonine kinase
BAD BCL2-associated agonist of cell death
BCAR1 breast cancer anti-estrogen resistance 1
BCL2 B-cell CLL/lymphoma 2
BCR breakpoint cluster region
BRCA2 breast cancer 2, early onset
BTK Bruton agammaglobulinemia tyrosine kinase
CASR calcium-sensing receptor
CAV1 caveolin 1, caveolae protein, 22kDa
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCND1 cyclin D1
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD22 CD22 molecule
CDC25C cell division cycle 25C
CDCA5 cell division cycle associated 5
CDK1 cyclin-dependent kinase 1
CDK9 cyclin-dependent kinase 9
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CHEK1 checkpoint kinase 1
CHEK2 checkpoint kinase 2
CHUK conserved helix-loop-helix ubiquitous kinase
CREB1 cAMP responsive element binding protein 1
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like
CTTN cortactin
DCK deoxycytidine kinase
DOCK1 dedicator of cytokinesis 1
DPYSL2 dihydropyrimidinase-like 2
DSP desmoplakin
EEF2 eukaryotic translation elongation factor 2
EEF2K eukaryotic elongation factor 2 kinase
EGFR epidermal growth factor receptor
EIF4E eukaryotic translation initiation factor 4E
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
ENO1 enolase 1, (alpha)
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
EWSR1 EWS RNA-binding protein 1
FANCD2 Fanconi anemia, complementation group D2
FAS Fas cell surface death receptor
FGD1 FYVE, RhoGEF and PH domain containing 1
FLCN folliculin
FLT3 fms-related tyrosine kinase 3
FOXA2 forkhead box A2
FOXO1 forkhead box O1
GATA1 GATA binding protein 1 (globin transcription factor 1)
GCSAM germinal center-associated, signaling and motility
GPSM2 G-protein signaling modulator 2
GRIA1 glutamate receptor, ionotropic, AMPA 1
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B
GSK3A glycogen synthase kinase 3 alpha
GSK3B glycogen synthase kinase 3 beta
GSTP1 glutathione S-transferase pi 1
H2AFX H2A histone family, member X
HIST1H3A histone cluster 1, H3a
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSPB1 heat shock 27kDa protein 1
HSPB6 heat shock protein, alpha-crystallin-related, B6
IFNAR1 interferon (alpha, beta and omega) receptor 1
IGFBP1 insulin-like growth factor binding protein 1
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IRS1 insulin receptor substrate 1
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
JAK1 Janus kinase 1
JUN jun proto-oncogene
KAT7 K(lysine) acetyltransferase 7
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KCNK2 potassium channel, two pore domain subfamily K, member 2
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
LCN1 lipocalin 1
LIPE lipase, hormone-sensitive
LRRC4C leucine rich repeat containing 4C
LYN LYN proto-oncogene, Src family tyrosine kinase
MAP2K4 mitogen-activated protein kinase kinase 4
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MAPK9 mitogen-activated protein kinase 9
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MAPT microtubule-associated protein tau
MCL1 myeloid cell leukemia 1
MCM2 minichromosome maintenance complex component 2
MCU mitochondrial calcium uniporter
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MDM4 MDM4, p53 regulator
MET MET proto-oncogene, receptor tyrosine kinase
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MYBBP1A MYB binding protein (P160) 1a
NBN nibrin
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
OPRM1 opioid receptor, mu 1
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2
PDE10A phosphodiesterase 10A
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDPK1 3-phosphoinositide dependent protein kinase 1
PEAK1 pseudopodium-enriched atypical kinase 1
PGRMC1 progesterone receptor membrane component 1
PHB prohibitin
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PLCG1 phospholipase C, gamma 1
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
PPP1R12A protein phosphatase 1, regulatory subunit 12A
PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PRKCA protein kinase C, alpha
PRKCE protein kinase C, epsilon
PRKCZ protein kinase C, zeta
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PTEN phosphatase and tensin homolog
PTK2 protein tyrosine kinase 2
PTK2B protein tyrosine kinase 2 beta
PTTG1IP pituitary tumor-transforming 1 interacting protein
PXN paxillin
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RB1 retinoblastoma 1
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RET ret proto-oncogene
RORA RAR-related orphan receptor A
RPS6 ribosomal protein S6
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
RXRA retinoid X receptor, alpha
SGK1 serum/glucocorticoid regulated kinase 1
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SHOX short stature homeobox
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1
SMAD2 SMAD family member 2
SMAD3 SMAD family member 3
SMC1A structural maintenance of chromosomes 1A
SP1 Sp1 transcription factor
SPIN1 spindlin 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SREBF1 sterol regulatory element binding transcription factor 1
SSTR2 somatostatin receptor 2
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT2 signal transducer and activator of transcription 2, 113kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT4 signal transducer and activator of transcription 4
STAT5A signal transducer and activator of transcription 5A
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
SYK spleen tyrosine kinase
SYN1 synapsin I
TACSTD2 tumor-associated calcium signal transducer 2
TGFBR1 transforming growth factor, beta receptor 1
TNNI3 troponin I type 3 (cardiac)
TNNT2 troponin T type 2 (cardiac)
TP53 tumor protein p53
TRIM28 tripartite motif containing 28
TRIP6 thyroid hormone receptor interactor 6
TSC1 tuberous sclerosis 1
TSC2 tuberous sclerosis 2
TTC3 tetratricopeptide repeat domain 3
TWIST1 twist family bHLH transcription factor 1
VASP vasodilator-stimulated phosphoprotein
WWOX WW domain containing oxidoreductase
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa