clioquinol-3084 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the clioquinol-3084 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAMDEC1 ADAM-like, decysin 1
ARL4C ADP-ribosylation factor-like 4C
ATF3 activating transcription factor 3
BIN1 bridging integrator 1
BIRC3 baculoviral IAP repeat containing 3
BLZF1 basic leucine zipper nuclear factor 1
C1QA complement component 1, q subcomponent, A chain
C20ORF27 chromosome 20 open reading frame 27
CD44 CD44 molecule (Indian blood group)
CDA cytidine deaminase
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CELSR3 cadherin, EGF LAG seven-pass G-type receptor 3
CLIP2 CAP-GLY domain containing linker protein 2
CPN2 carboxypeptidase N, polypeptide 2
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CREM cAMP responsive element modulator
CSRP2 cysteine and glycine-rich protein 2
CTSZ cathepsin Z
DDN dendrin
DLG4 discs, large homolog 4 (Drosophila)
DRD5 dopamine receptor D5
EDRF1 erythroid differentiation regulatory factor 1
ETV4 ets variant 4
FAM131A family with sequence similarity 131, member A
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
FLRT2 fibronectin leucine rich transmembrane protein 2
FLT1 fms-related tyrosine kinase 1
FOSL2 FOS-like antigen 2
FOXD2 forkhead box D2
FST follistatin
GEM GTP binding protein overexpressed in skeletal muscle
GOSR2 golgi SNAP receptor complex member 2
HCAR3 hydroxycarboxylic acid receptor 3
HOXD11 homeobox D11
HRH3 histamine receptor H3
ICAM1 intercellular adhesion molecule 1
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IGHMBP2 immunoglobulin mu binding protein 2
IGLL1 immunoglobulin lambda-like polypeptide 1
IL1B interleukin 1, beta
IL1R1 interleukin 1 receptor, type I
IL24 interleukin 24
INPP5J inositol polyphosphate-5-phosphatase J
KCNG1 potassium channel, voltage gated modifier subfamily G, member 1
KLHL36 kelch-like family member 36
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAOA monoamine oxidase A
MAPK11 mitogen-activated protein kinase 11
MMP1 matrix metallopeptidase 1
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1G metallothionein 1G
MT1H metallothionein 1H
MT1HL1 metallothionein 1H-like 1
MT1M metallothionein 1M
MT1X metallothionein 1X
MT2A metallothionein 2A
MTAP methylthioadenosine phosphorylase
MX1 MX dynamin-like GTPase 1
NR2F2 nuclear receptor subfamily 2, group F, member 2
NR4A3 nuclear receptor subfamily 4, group A, member 3
NRF1 nuclear respiratory factor 1
NRP1 neuropilin 1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
NUDCD3 NudC domain containing 3
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OASL 2'-5'-oligoadenylate synthetase-like
PCBP4 poly(rC) binding protein 4
PCLO piccolo presynaptic cytomatrix protein
PHLDA1 pleckstrin homology-like domain, family A, member 1
PRR7 proline rich 7 (synaptic)
PRX periaxin
PTGES prostaglandin E synthase
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RAB11FIP3 RAB11 family interacting protein 3 (class II)
RAD52 RAD52 homolog (S. cerevisiae)
RASAL1 RAS protein activator like 1 (GAP1 like)
RELN reelin
RUNX2 runt-related transcription factor 2
SAYSD1 SAYSVFN motif domain containing 1
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SH3BGR SH3 domain binding glutamate-rich protein
SHMT1 serine hydroxymethyltransferase 1 (soluble)
SIX3 SIX homeobox 3
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SNAP25 synaptosomal-associated protein, 25kDa
SYN3 synapsin III
TEX14 testis expressed 14
TEX15 testis expressed 15
THBS1 thrombospondin 1
TMEM176B transmembrane protein 176B
TMEM2 transmembrane protein 2
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TRIM3 tripartite motif containing 3
TSC22D1 TSC22 domain family, member 1
VGF VGF nerve growth factor inducible
ZXDB zinc finger, X-linked, duplicated B

decreased expression

Symbol Name
A1CF APOBEC1 complementation factor
AAAS achalasia, adrenocortical insufficiency, alacrimia
ACYP1 acylphosphatase 1, erythrocyte (common) type
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
AP4M1 adaptor-related protein complex 4, mu 1 subunit
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
BEND5 BEN domain containing 5
BTBD2 BTB (POZ) domain containing 2
C14ORF93 chromosome 14 open reading frame 93
C5ORF45 chromosome 5 open reading frame 45
C7ORF43 chromosome 7 open reading frame 43
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
CHST10 carbohydrate sulfotransferase 10
CLDN15 claudin 15
CTSO cathepsin O
DECR2 2,4-dienoyl CoA reductase 2, peroxisomal
DEXI Dexi homolog (mouse)
DNMBP dynamin binding protein
ELSPBP1 epididymal sperm binding protein 1
ENDOD1 endonuclease domain containing 1
F13A1 coagulation factor XIII, A1 polypeptide
FBXW4P1 F-box and WD repeat domain containing 4 pseudogene 1
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64)
FES FES proto-oncogene, tyrosine kinase
FGF9 fibroblast growth factor 9
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GAMT guanidinoacetate N-methyltransferase
GDAP1 ganglioside induced differentiation associated protein 1
GPR132 G protein-coupled receptor 132
GSDMD gasdermin D
GSTZ1 glutathione S-transferase zeta 1
GTF2A1 general transcription factor IIA, 1, 19/37kDa
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HAMP hepcidin antimicrobial peptide
HDHD3 haloacid dehalogenase-like hydrolase domain containing 3
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HMGA2 high mobility group AT-hook 2
HSPA4L heat shock 70kDa protein 4-like
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KIAA1107 KIAA1107
KIF20A kinesin family member 20A
KIF23 kinesin family member 23
LGR4 leucine-rich repeat containing G protein-coupled receptor 4
LINC00339 long intergenic non-protein coding RNA 339
LOC730101 uncharacterized LOC730101
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MBTD1 mbt domain containing 1
METTL8 methyltransferase like 8
MRPL28 mitochondrial ribosomal protein L28
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A
NCS1 neuronal calcium sensor 1
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PCDHGB5 protocadherin gamma subfamily B, 5
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PDGFRL platelet-derived growth factor receptor-like
PGP phosphoglycolate phosphatase
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PRF1 perforin 1 (pore forming protein)
PSG4 pregnancy specific beta-1-glycoprotein 4
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like
PYGB phosphorylase, glycogen; brain
QSER1 glutamine and serine rich 1
QTRT1 queuine tRNA-ribosyltransferase 1
RPL23AP32 ribosomal protein L23a pseudogene 32
RRAGB Ras-related GTP binding B
SCD5 stearoyl-CoA desaturase 5
SCGB2A2 secretoglobin, family 2A, member 2
SIL1 SIL1 nucleotide exchange factor
SIRT6 sirtuin 6
SLC15A3 solute carrier family 15 (oligopeptide transporter), member 3
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3
SOX12 SRY (sex determining region Y)-box 12
ST7L suppression of tumorigenicity 7 like
STX11 syntaxin 11
SURF2 surfeit 2
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila)
TEC tec protein tyrosine kinase
THBS3 thrombospondin 3
TIAM2 T-cell lymphoma invasion and metastasis 2
TIGD6 tigger transposable element derived 6
TMEM140 transmembrane protein 140
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TPM3 tropomyosin 3
TRIM45 tripartite motif containing 45
TSC22D4 TSC22 domain family, member 4
TTC23 tetratricopeptide repeat domain 23
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
UPK3A uroplakin 3A
VNN1 vanin 1
WASF3 WAS protein family, member 3
ZC2HC1A zinc finger, C2HC-type containing 1A
ZHX2 zinc fingers and homeoboxes 2
ZNF280B zinc finger protein 280B
ZNF552 zinc finger protein 552
ZNF696 zinc finger protein 696
ZNF862 zinc finger protein 862