| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the clioquinol-5258 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AKAP6 | A kinase (PRKA) anchor protein 6 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) |
| APOE | apolipoprotein E |
| ARL4C | ADP-ribosylation factor-like 4C |
| ASPH | aspartate beta-hydroxylase |
| ATF3 | activating transcription factor 3 |
| B4GALT6 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic |
| BGN | biglycan |
| CACNG1 | calcium channel, voltage-dependent, gamma subunit 1 |
| CAMSAP1 | calmodulin regulated spectrin-associated protein 1 |
| CCNJL | cyclin J-like |
| CD79B | CD79b molecule, immunoglobulin-associated beta |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CLGN | calmegin |
| COL13A1 | collagen, type XIII, alpha 1 |
| COL19A1 | collagen, type XIX, alpha 1 |
| COL1A1 | collagen, type I, alpha 1 |
| CRMP1 | collapsin response mediator protein 1 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DLX2 | distal-less homeobox 2 |
| DOCK10 | dedicator of cytokinesis 10 |
| ETV5 | ets variant 5 |
| FARP2 | FERM, RhoGEF and pleckstrin domain protein 2 |
| FBXO2 | F-box protein 2 |
| FCGR3B | Fc fragment of IgG, low affinity IIIb, receptor (CD16b) |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) |
| GAD2 | glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) |
| GALR3 | galanin receptor 3 |
| GNAT2 | guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 |
| GPR22 | G protein-coupled receptor 22 |
| HECW1 | HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 |
| HFE | hemochromatosis |
| HMOX1 | heme oxygenase 1 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IGL | immunoglobulin lambda locus |
| INHBE | inhibin, beta E |
| ITGA7 | integrin, alpha 7 |
| KANSL3 | KAT8 regulatory NSL complex subunit 3 |
| KIAA0485 | uncharacterized LOC57235 |
| KRT38 | keratin 38, type I |
| KRT85 | keratin 85, type II |
| LOC644450 | uncharacterized LOC644450 |
| LOXL3 | lysyl oxidase-like 3 |
| LTC4S | leukotriene C4 synthase |
| MAGEA5 | melanoma antigen family A5 |
| MAP2K5 | mitogen-activated protein kinase kinase 5 |
| MC2R | melanocortin 2 receptor (adrenocorticotropic hormone) |
| MCFD2 | multiple coagulation factor deficiency 2 |
| MT1E | metallothionein 1E |
| MT1F | metallothionein 1F |
| MT1G | metallothionein 1G |
| MT1H | metallothionein 1H |
| MT1HL1 | metallothionein 1H-like 1 |
| MT1X | metallothionein 1X |
| MT2A | metallothionein 2A |
| NAT6 | N-acetyltransferase 6 (GCN5-related) |
| NFATC1 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| OPLAH | 5-oxoprolinase (ATP-hydrolysing) |
| PCDH9 | protocadherin 9 |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) |
| PI4K2A | phosphatidylinositol 4-kinase type 2 alpha |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| PNPLA4 | patatin-like phospholipase domain containing 4 |
| PPFIBP2 | PTPRF interacting protein, binding protein 2 (liprin beta 2) |
| PRDM14 | PR domain containing 14 |
| RAB6B | RAB6B, member RAS oncogene family |
| RECQL5 | RecQ protein-like 5 |
| RNF125 | ring finger protein 125, E3 ubiquitin protein ligase |
| SCN10A | sodium channel, voltage gated, type X alpha subunit |
| SH3TC1 | SH3 domain and tetratricopeptide repeats 1 |
| SLC10A1 | solute carrier family 10 (sodium/bile acid cotransporter), member 1 |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| SLC43A3 | solute carrier family 43, member 3 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SRF | serum response factor (c-fos serum response element-binding transcription factor) |
| STMN3 | stathmin-like 3 |
| SWAP70 | SWAP switching B-cell complex 70kDa subunit |
| SYN2 | synapsin II |
| SYT11 | synaptotagmin XI |
| TAS2R4 | taste receptor, type 2, member 4 |
| TBC1D22A | TBC1 domain family, member 22A |
| TBX3 | T-box 3 |
| TJAP1 | tight junction associated protein 1 (peripheral) |
| TMPRSS15 | transmembrane protease, serine 15 |
| TRIM10 | tripartite motif containing 10 |
| TTLL7 | tubulin tyrosine ligase-like family member 7 |
| VAMP5 | vesicle-associated membrane protein 5 |
| VEGFA | vascular endothelial growth factor A |
| VLDLR | very low density lipoprotein receptor |
| ZFHX2 | zinc finger homeobox 2 |
| Symbol | Name |
|---|---|
| ACYP1 | acylphosphatase 1, erythrocyte (common) type |
| ADTRP | androgen-dependent TFPI-regulating protein |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 |
| ARRB1 | arrestin, beta 1 |
| BAG4 | BCL2-associated athanogene 4 |
| BMP4 | bone morphogenetic protein 4 |
| C19ORF40 | chromosome 19 open reading frame 40 |
| CCNE1 | cyclin E1 |
| CCNL2 | cyclin L2 |
| CCRN4L | CCR4 carbon catabolite repression 4-like (S. cerevisiae) |
| CD302 | CD302 molecule |
| CDK20 | cyclin-dependent kinase 20 |
| CENPO | centromere protein O |
| CENPT | centromere protein T |
| CLCF1 | cardiotrophin-like cytokine factor 1 |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CORO1A | coronin, actin binding protein, 1A |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DVL1 | dishevelled segment polarity protein 1 |
| EFCAB2 | EF-hand calcium binding domain 2 |
| FBXL6 | F-box and leucine-rich repeat protein 6 |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| GAN | gigaxonin |
| GATA4 | GATA binding protein 4 |
| GPR27 | G protein-coupled receptor 27 |
| GRAMD4 | GRAM domain containing 4 |
| HCFC2 | host cell factor C2 |
| HIST1H4F | histone cluster 1, H4f |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 |
| IFI27 | interferon, alpha-inducible protein 27 |
| IFT140 | intraflagellar transport 140 |
| KIAA0319L | KIAA0319-like |
| KIFC1 | kinesin family member C1 |
| KLHL28 | kelch-like family member 28 |
| KLK6 | kallikrein-related peptidase 6 |
| KREMEN2 | kringle containing transmembrane protein 2 |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LIN7A | lin-7 homolog A (C. elegans) |
| LINC00597 | long intergenic non-protein coding RNA 597 |
| LMNB1 | lamin B1 |
| LOC730101 | uncharacterized LOC730101 |
| MAP1S | microtubule-associated protein 1S |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| METTL16 | methyltransferase like 16 |
| MFAP2 | microfibrillar-associated protein 2 |
| MMP15 | matrix metallopeptidase 15 (membrane-inserted) |
| MTERF4 | mitochondrial transcription termination factor 4 |
| MVD | mevalonate (diphospho) decarboxylase |
| MXD3 | MAX dimerization protein 3 |
| MYO1F | myosin IF |
| NDE1 | nudE neurodevelopment protein 1 |
| NLRX1 | NLR family member X1 |
| NOS1AP | nitric oxide synthase 1 (neuronal) adaptor protein |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| NPY1R | neuropeptide Y receptor Y1 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) |
| OR2B6 | olfactory receptor, family 2, subfamily B, member 6 |
| OSGIN1 | oxidative stress induced growth inhibitor 1 |
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 |
| PCDHA5 | protocadherin alpha 5 |
| PCDHA6 | protocadherin alpha 6 |
| PCDHB13 | protocadherin beta 13 |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PDLIM2 | PDZ and LIM domain 2 (mystique) |
| PDZK1 | PDZ domain containing 1 |
| PDZRN3 | PDZ domain containing ring finger 3 |
| PGR | progesterone receptor |
| PLA2G4C | phospholipase A2, group IVC (cytosolic, calcium-independent) |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| PMCH | pro-melanin-concentrating hormone |
| PMP22 | peripheral myelin protein 22 |
| POLR3D | polymerase (RNA) III (DNA directed) polypeptide D, 44kDa |
| RAD51AP1 | RAD51 associated protein 1 |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| S100A9 | S100 calcium binding protein A9 |
| SETD1A | SET domain containing 1A |
| SLC12A6 | solute carrier family 12 (potassium/chloride transporter), member 6 |
| SLC39A1 | solute carrier family 39 (zinc transporter), member 1 |
| SLC46A3 | solute carrier family 46, member 3 |
| SNN | stannin |
| SNX15 | sorting nexin 15 |
| STK16 | serine/threonine kinase 16 |
| TIMM13 | translocase of inner mitochondrial membrane 13 homolog (yeast) |
| TM7SF3 | transmembrane 7 superfamily member 3 |
| TMUB2 | transmembrane and ubiquitin-like domain containing 2 |
| TNFSF18 | tumor necrosis factor (ligand) superfamily, member 18 |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 |
| TRAPPC2 | trafficking protein particle complex 2 |
| TRIM32 | tripartite motif containing 32 |
| TSPO | translocator protein (18kDa) |
| UBQLN4 | ubiquilin 4 |
| ZBTB33 | zinc finger and BTB domain containing 33 |
| ZNF41 | zinc finger protein 41 |
| ZNF669 | zinc finger protein 669 |
