| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the clioquinol-5623 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| AMPD3 | adenosine monophosphate deaminase 3 |
| ANK1 | ankyrin 1, erythrocytic |
| APOBEC2 | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2 |
| ARNT | aryl hydrocarbon receptor nuclear translocator |
| ASIC3 | acid sensing (proton gated) ion channel 3 |
| ATF3 | activating transcription factor 3 |
| ATP10A | ATPase, class V, type 10A |
| BGN | biglycan |
| BIRC3 | baculoviral IAP repeat containing 3 |
| BRF1 | BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit |
| BTG2 | BTG family, member 2 |
| C11ORF16 | chromosome 11 open reading frame 16 |
| CARD14 | caspase recruitment domain family, member 14 |
| CCR7 | chemokine (C-C motif) receptor 7 |
| CD4 | CD4 molecule |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) |
| CHST5 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5 |
| CLCN7 | chloride channel, voltage-sensitive 7 |
| CLTC | clathrin, heavy chain (Hc) |
| CNTD2 | cyclin N-terminal domain containing 2 |
| CNTN1 | contactin 1 |
| CNTNAP1 | contactin associated protein 1 |
| COL16A1 | collagen, type XVI, alpha 1 |
| CRMP1 | collapsin response mediator protein 1 |
| CTSE | cathepsin E |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
| CYP27A1 | cytochrome P450, family 27, subfamily A, polypeptide 1 |
| DCTN1 | dynactin 1 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked |
| DLX2 | distal-less homeobox 2 |
| DRD2 | dopamine receptor D2 |
| EDNRA | endothelin receptor type A |
| EGR1 | early growth response 1 |
| EVA1B | eva-1 homolog B (C. elegans) |
| FABP6 | fatty acid binding protein 6, ileal |
| FBLN1 | fibulin 1 |
| FEZ1 | fasciculation and elongation protein zeta 1 (zygin I) |
| FGF13 | fibroblast growth factor 13 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B |
| FOXN3 | forkhead box N3 |
| FRMD4B | FERM domain containing 4B |
| GABBR1 | gamma-aminobutyric acid (GABA) B receptor, 1 |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| GGT1 | gamma-glutamyltransferase 1 |
| HIST1H4H | histone cluster 1, H4h |
| HMOX1 | heme oxygenase 1 |
| IFFO1 | intermediate filament family orphan 1 |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| IL2RG | interleukin 2 receptor, gamma |
| INHBE | inhibin, beta E |
| KERA | keratocan |
| KIF21B | kinesin family member 21B |
| LIF | leukemia inhibitory factor |
| LINC00312 | long intergenic non-protein coding RNA 312 |
| LOC729164 | hCG1732469 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MT1E | metallothionein 1E |
| MT1F | metallothionein 1F |
| MT1G | metallothionein 1G |
| MT1H | metallothionein 1H |
| MT1HL1 | metallothionein 1H-like 1 |
| MT1X | metallothionein 1X |
| MT2A | metallothionein 2A |
| MTMR8 | myotubularin related protein 8 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase |
| NEK9 | NIMA-related kinase 9 |
| NKX2-5 | NK2 homeobox 5 |
| NOVA2 | neuro-oncological ventral antigen 2 |
| NPY6R | neuropeptide Y receptor Y6 (pseudogene) |
| NTM | neurotrimin |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| OASL | 2'-5'-oligoadenylate synthetase-like |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PLCL2 | phospholipase C-like 2 |
| PLD1 | phospholipase D1, phosphatidylcholine-specific |
| PLXNB1 | plexin B1 |
| PPARD | peroxisome proliferator-activated receptor delta |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| RND1 | Rho family GTPase 1 |
| RORC | RAR-related orphan receptor C |
| RRN3P1 | RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1 |
| SLC11A1 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 |
| SLC43A3 | solute carrier family 43, member 3 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SP100 | SP100 nuclear antigen |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 |
| TAC3 | tachykinin 3 |
| TBC1D22B | TBC1 domain family, member 22B |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TOM1 | target of myb1 (chicken) |
| WSCD1 | WSC domain containing 1 |
| ZNF419 | zinc finger protein 419 |
| ZNF639 | zinc finger protein 639 |
| Symbol | Name |
|---|---|
| A1CF | APOBEC1 complementation factor |
| ABLIM3 | actin binding LIM protein family, member 3 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 |
| ALPK1 | alpha-kinase 1 |
| ALS2CL | ALS2 C-terminal like |
| AMT | aminomethyltransferase |
| BHLHE41 | basic helix-loop-helix family, member e41 |
| BMP4 | bone morphogenetic protein 4 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 |
| C14ORF79 | chromosome 14 open reading frame 79 |
| CCDC134 | coiled-coil domain containing 134 |
| CD82 | CD82 molecule |
| CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) |
| CES3 | carboxylesterase 3 |
| CLEC4E | C-type lectin domain family 4, member E |
| CORT | cortistatin |
| CRIP1 | cysteine-rich protein 1 (intestinal) |
| CRY2 | cryptochrome circadian clock 2 |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| DGKE | diacylglycerol kinase, epsilon 64kDa |
| DNAJC28 | DnaJ (Hsp40) homolog, subfamily C, member 28 |
| DSPP | dentin sialophosphoprotein |
| EFNA3 | ephrin-A3 |
| ELOVL4 | ELOVL fatty acid elongase 4 |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| EVPL | envoplakin |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FBXO5 | F-box protein 5 |
| FFAR2 | free fatty acid receptor 2 |
| FRK | fyn-related Src family tyrosine kinase |
| FRS2 | fibroblast growth factor receptor substrate 2 |
| GALK1 | galactokinase 1 |
| GFI1 | growth factor independent 1 transcription repressor |
| GRB7 | growth factor receptor-bound protein 7 |
| GRPR | gastrin-releasing peptide receptor |
| HDAC11 | histone deacetylase 11 |
| IL12RB1 | interleukin 12 receptor, beta 1 |
| IRAK4 | interleukin-1 receptor-associated kinase 4 |
| KIAA0319L | KIAA0319-like |
| KIAA0355 | KIAA0355 |
| KLF2 | Kruppel-like factor 2 |
| LINC00597 | long intergenic non-protein coding RNA 597 |
| LYPD1 | LY6/PLAUR domain containing 1 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase |
| METTL2B | methyltransferase like 2B |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 |
| MLYCD | malonyl-CoA decarboxylase |
| MORC3 | MORC family CW-type zinc finger 3 |
| MRPL41 | mitochondrial ribosomal protein L41 |
| MTHFD2L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like |
| MXD3 | MAX dimerization protein 3 |
| NME5 | NME/NM23 family member 5 |
| NPY5R | neuropeptide Y receptor Y5 |
| NUP62CL | nucleoporin 62kDa C-terminal like |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PC | pyruvate carboxylase |
| PCSK1N | proprotein convertase subtilisin/kexin type 1 inhibitor |
| PDE6B | phosphodiesterase 6B, cGMP-specific, rod, beta |
| PDE6C | phosphodiesterase 6C, cGMP-specific, cone, alpha prime |
| PDK1 | pyruvate dehydrogenase kinase, isozyme 1 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| PMCH | pro-melanin-concentrating hormone |
| PODXL2 | podocalyxin-like 2 |
| POM121L2 | POM121 transmembrane nucleoporin-like 2 |
| PVRL3 | poliovirus receptor-related 3 |
| PYCRL | pyrroline-5-carboxylate reductase-like |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| RAB3D | RAB3D, member RAS oncogene family |
| RFXAP | regulatory factor X-associated protein |
| RGS2 | regulator of G-protein signaling 2 |
| RP2 | retinitis pigmentosa 2 (X-linked recessive) |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 |
| SGCE | sarcoglycan, epsilon |
| SLC2A8 | solute carrier family 2 (facilitated glucose transporter), member 8 |
| SLC47A1 | solute carrier family 47 (multidrug and toxin extrusion), member 1 |
| STARD5 | StAR-related lipid transfer (START) domain containing 5 |
| TCHH | trichohyalin |
| TEP1 | telomerase-associated protein 1 |
| TGFBR1 | transforming growth factor, beta receptor 1 |
| TMEM254 | transmembrane protein 254 |
| TRIM36 | tripartite motif containing 36 |
| TRPC5 | transient receptor potential cation channel, subfamily C, member 5 |
| TTLL1 | tubulin tyrosine ligase-like family member 1 |
| TUBA3C | tubulin, alpha 3c |
| TWSG1 | twisted gastrulation BMP signaling modulator 1 |
| UBTD1 | ubiquitin domain containing 1 |
| UNC119 | unc-119 homolog (C. elegans) |
| VAX2 | ventral anterior homeobox 2 |
| XAB2 | XPA binding protein 2 |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZKSCAN3 | zinc finger with KRAB and SCAN domains 3 |
| ZNF141 | zinc finger protein 141 |
| ZNF204P | zinc finger protein 204, pseudogene |
| ZNF350 | zinc finger protein 350 |
| ZNF551 | zinc finger protein 551 |
| ZNF804A | zinc finger protein 804A |
