| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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196 genes differentially expressed following the clioquinol-6461 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCB6 | ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) |
| ADGRB3 | adhesion G protein-coupled receptor B3 |
| ALDH1B1 | aldehyde dehydrogenase 1 family, member B1 |
| AMPD3 | adenosine monophosphate deaminase 3 |
| BCO1 | beta-carotene oxygenase 1 |
| BMP1 | bone morphogenetic protein 1 |
| C1ORF54 | chromosome 1 open reading frame 54 |
| CABP1 | calcium binding protein 1 |
| CASP1 | caspase 1, apoptosis-related cysteine peptidase |
| CCNG2 | cyclin G2 |
| CDKN2A | cyclin-dependent kinase inhibitor 2A |
| CFAP69 | cilia and flagella associated protein 69 |
| CHRNA6 | cholinergic receptor, nicotinic, alpha 6 (neuronal) |
| CMAHP | cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene |
| COL8A1 | collagen, type VIII, alpha 1 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
| DGCR2 | DiGeorge syndrome critical region gene 2 |
| DICER1 | dicer 1, ribonuclease type III |
| DIEXF | digestive organ expansion factor homolog (zebrafish) |
| DIO2 | deiodinase, iodothyronine, type II |
| DNASE1L3 | deoxyribonuclease I-like 3 |
| DPYS | dihydropyrimidinase |
| DYNC1LI2 | dynein, cytoplasmic 1, light intermediate chain 2 |
| EFS | embryonal Fyn-associated substrate |
| EMX1 | empty spiracles homeobox 1 |
| ESR1 | estrogen receptor 1 |
| EXOSC1 | exosome component 1 |
| FFAR2 | free fatty acid receptor 2 |
| FGD1 | FYVE, RhoGEF and PH domain containing 1 |
| FOXG1 | forkhead box G1 |
| GCGR | glucagon receptor |
| GLRA3 | glycine receptor, alpha 3 |
| GPR157 | G protein-coupled receptor 157 |
| HAO2 | hydroxyacid oxidase 2 (long chain) |
| HDAC7 | histone deacetylase 7 |
| HLF | hepatic leukemia factor |
| HNF4A | hepatocyte nuclear factor 4, alpha |
| IL1RN | interleukin 1 receptor antagonist |
| INHBA | inhibin, beta A |
| ITGB4 | integrin, beta 4 |
| KANK1 | KN motif and ankyrin repeat domains 1 |
| KCNH2 | potassium channel, voltage gated eag related subfamily H, member 2 |
| KRIT1 | KRIT1, ankyrin repeat containing |
| L3MBTL1 | l(3)mbt-like 1 (Drosophila) |
| LIMK1 | LIM domain kinase 1 |
| LOC100129648 | uncharacterized LOC100129648 |
| MAL | mal, T-cell differentiation protein |
| MECOM | MDS1 and EVI1 complex locus |
| MFAP5 | microfibrillar associated protein 5 |
| MT1E | metallothionein 1E |
| MT1F | metallothionein 1F |
| MT1G | metallothionein 1G |
| MT1H | metallothionein 1H |
| MT1HL1 | metallothionein 1H-like 1 |
| MT1X | metallothionein 1X |
| MT2A | metallothionein 2A |
| NDRG2 | NDRG family member 2 |
| NLE1 | notchless homolog 1 (Drosophila) |
| P2RY13 | purinergic receptor P2Y, G-protein coupled, 13 |
| PDE6B | phosphodiesterase 6B, cGMP-specific, rod, beta |
| PDGFB | platelet-derived growth factor beta polypeptide |
| PDPN | podoplanin |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) |
| PLCL2 | phospholipase C-like 2 |
| POFUT1 | protein O-fucosyltransferase 1 |
| POU4F2 | POU class 4 homeobox 2 |
| PPP1R37 | protein phosphatase 1, regulatory subunit 37 |
| PQLC2 | PQ loop repeat containing 2 |
| QSER1 | glutamine and serine rich 1 |
| RNF122 | ring finger protein 122 |
| SCAPER | S-phase cyclin A-associated protein in the ER |
| SCN2B | sodium channel, voltage gated, type II beta subunit |
| SEMA3F | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F |
| SEMA6D | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D |
| SGCE | sarcoglycan, epsilon |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 |
| SOS1 | son of sevenless homolog 1 (Drosophila) |
| STK17B | serine/threonine kinase 17b |
| TAPBP | TAP binding protein (tapasin) |
| TDRD12 | tudor domain containing 12 |
| TMEM53 | transmembrane protein 53 |
| TNFSF4 | tumor necrosis factor (ligand) superfamily, member 4 |
| TNK2 | tyrosine kinase, non-receptor, 2 |
| TREX1 | three prime repair exonuclease 1 |
| UBE2B | ubiquitin-conjugating enzyme E2B |
| ULBP2 | UL16 binding protein 2 |
| VIPR1 | vasoactive intestinal peptide receptor 1 |
| WSCD1 | WSC domain containing 1 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 |
| ZMAT4 | zinc finger, matrin-type 4 |
| ZNF137P | zinc finger protein 137, pseudogene |
| ZNF536 | zinc finger protein 536 |
| ZNF614 | zinc finger protein 614 |
| ZNF750 | zinc finger protein 750 |
| Symbol | Name |
|---|---|
| ADAM15 | ADAM metallopeptidase domain 15 |
| AFAP1 | actin filament associated protein 1 |
| AFF4 | AF4/FMR2 family, member 4 |
| AFG3L2 | AFG3-like AAA ATPase 2 |
| AHCTF1 | AT hook containing transcription factor 1 |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| ALOX15 | arachidonate 15-lipoxygenase |
| AP4M1 | adaptor-related protein complex 4, mu 1 subunit |
| B3GNT2 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 |
| BHLHB9 | basic helix-loop-helix domain containing, class B, 9 |
| C19ORF40 | chromosome 19 open reading frame 40 |
| C1ORF159 | chromosome 1 open reading frame 159 |
| C22ORF29 | chromosome 22 open reading frame 29 |
| C5AR2 | complement component 5a receptor 2 |
| CCDC132 | coiled-coil domain containing 132 |
| CEBPZ | CCAAT/enhancer binding protein (C/EBP), zeta |
| CENPJ | centromere protein J |
| CENPT | centromere protein T |
| CFD | complement factor D (adipsin) |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| CYP2J2 | cytochrome P450, family 2, subfamily J, polypeptide 2 |
| CYP2R1 | cytochrome P450, family 2, subfamily R, polypeptide 1 |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 |
| DNAJC28 | DnaJ (Hsp40) homolog, subfamily C, member 28 |
| DNM1 | dynamin 1 |
| EFNA3 | ephrin-A3 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 |
| FRK | fyn-related Src family tyrosine kinase |
| GABPA | GA binding protein transcription factor, alpha subunit 60kDa |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GID4 | GID complex subunit 4 |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GNL3LP1 | guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1 |
| GPATCH3 | G patch domain containing 3 |
| HIST1H1B | histone cluster 1, H1b |
| HOXB2 | homeobox B2 |
| HOXC5 | homeobox C5 |
| HSPA1L | heat shock 70kDa protein 1-like |
| HTR1E | 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled |
| IL12RB1 | interleukin 12 receptor, beta 1 |
| INO80D | INO80 complex subunit D |
| KLHL21 | kelch-like family member 21 |
| KLK5 | kallikrein-related peptidase 5 |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LOC729164 | hCG1732469 |
| LRP3 | low density lipoprotein receptor-related protein 3 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 |
| MBIP | MAP3K12 binding inhibitory protein 1 |
| MC1R | melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) |
| MCTP1 | multiple C2 domains, transmembrane 1 |
| NACA2 | nascent polypeptide-associated complex alpha subunit 2 |
| NPY5R | neuropeptide Y receptor Y5 |
| NUP62CL | nucleoporin 62kDa C-terminal like |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| OXTR | oxytocin receptor |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PANX1 | pannexin 1 |
| PCDHA9 | protocadherin alpha 9 |
| PMCHL1 | pro-melanin-concentrating hormone-like 1, pseudogene |
| PROL1 | proline rich, lacrimal 1 |
| RAB3A | RAB3A, member RAS oncogene family |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| RPS17P5 | ribosomal protein S17 pseudogene 5 |
| SCML2 | sex comb on midleg-like 2 (Drosophila) |
| SEC61A2 | Sec61 alpha 2 subunit (S. cerevisiae) |
| SECTM1 | secreted and transmembrane 1 |
| SFRP5 | secreted frizzled-related protein 5 |
| SIGLEC15 | sialic acid binding Ig-like lectin 15 |
| SIRAL2 | SIR2 antiphage like 2 |
| SLC12A9 | solute carrier family 12, member 9 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SNIP1 | Smad nuclear interacting protein 1 |
| SSFA2 | sperm specific antigen 2 |
| STARD5 | StAR-related lipid transfer (START) domain containing 5 |
| STON1 | stonin 1 |
| SUSD6 | sushi domain containing 6 |
| TCHH | trichohyalin |
| TMEM183A | transmembrane protein 183A |
| TOM1 | target of myb1 (chicken) |
| TRIP10 | thyroid hormone receptor interactor 10 |
| TTBK2 | tau tubulin kinase 2 |
| TTC33 | tetratricopeptide repeat domain 33 |
| TWF2 | twinfilin actin binding protein 2 |
| UBQLN4 | ubiquilin 4 |
| USP27X | ubiquitin specific peptidase 27, X-linked |
| VASH1 | vasohibin 1 |
| VEGFB | vascular endothelial growth factor B |
| XPNPEP3 | X-prolyl aminopeptidase 3, mitochondrial |
| ZNF189 | zinc finger protein 189 |
| ZNF204P | zinc finger protein 204, pseudogene |
| ZNF212 | zinc finger protein 212 |
| ZNF324 | zinc finger protein 324 |
| ZNF654 | zinc finger protein 654 |