clioquinol-6461 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the clioquinol-6461 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ADGRB3 adhesion G protein-coupled receptor B3
ALDH1B1 aldehyde dehydrogenase 1 family, member B1
AMPD3 adenosine monophosphate deaminase 3
BCO1 beta-carotene oxygenase 1
BMP1 bone morphogenetic protein 1
C1ORF54 chromosome 1 open reading frame 54
CABP1 calcium binding protein 1
CASP1 caspase 1, apoptosis-related cysteine peptidase
CCNG2 cyclin G2
CDKN2A cyclin-dependent kinase inhibitor 2A
CFAP69 cilia and flagella associated protein 69
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
CMAHP cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene
COL8A1 collagen, type VIII, alpha 1
CPED1 cadherin-like and PC-esterase domain containing 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DGCR2 DiGeorge syndrome critical region gene 2
DICER1 dicer 1, ribonuclease type III
DIEXF digestive organ expansion factor homolog (zebrafish)
DIO2 deiodinase, iodothyronine, type II
DNASE1L3 deoxyribonuclease I-like 3
DPYS dihydropyrimidinase
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2
EFS embryonal Fyn-associated substrate
EMX1 empty spiracles homeobox 1
ESR1 estrogen receptor 1
EXOSC1 exosome component 1
FFAR2 free fatty acid receptor 2
FGD1 FYVE, RhoGEF and PH domain containing 1
FOXG1 forkhead box G1
GCGR glucagon receptor
GLRA3 glycine receptor, alpha 3
GPR157 G protein-coupled receptor 157
HAO2 hydroxyacid oxidase 2 (long chain)
HDAC7 histone deacetylase 7
HLF hepatic leukemia factor
HNF4A hepatocyte nuclear factor 4, alpha
IL1RN interleukin 1 receptor antagonist
INHBA inhibin, beta A
ITGB4 integrin, beta 4
KANK1 KN motif and ankyrin repeat domains 1
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KRIT1 KRIT1, ankyrin repeat containing
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LIMK1 LIM domain kinase 1
LOC100129648 uncharacterized LOC100129648
MAL mal, T-cell differentiation protein
MECOM MDS1 and EVI1 complex locus
MFAP5 microfibrillar associated protein 5
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1G metallothionein 1G
MT1H metallothionein 1H
MT1HL1 metallothionein 1H-like 1
MT1X metallothionein 1X
MT2A metallothionein 2A
NDRG2 NDRG family member 2
NLE1 notchless homolog 1 (Drosophila)
P2RY13 purinergic receptor P2Y, G-protein coupled, 13
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PDGFB platelet-derived growth factor beta polypeptide
PDPN podoplanin
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PLCL2 phospholipase C-like 2
POFUT1 protein O-fucosyltransferase 1
POU4F2 POU class 4 homeobox 2
PPP1R37 protein phosphatase 1, regulatory subunit 37
PQLC2 PQ loop repeat containing 2
QSER1 glutamine and serine rich 1
RNF122 ring finger protein 122
SCAPER S-phase cyclin A-associated protein in the ER
SCN2B sodium channel, voltage gated, type II beta subunit
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
SEMA6D sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
SGCE sarcoglycan, epsilon
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SOS1 son of sevenless homolog 1 (Drosophila)
STK17B serine/threonine kinase 17b
TAPBP TAP binding protein (tapasin)
TDRD12 tudor domain containing 12
TMEM53 transmembrane protein 53
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4
TNK2 tyrosine kinase, non-receptor, 2
TREX1 three prime repair exonuclease 1
UBE2B ubiquitin-conjugating enzyme E2B
ULBP2 UL16 binding protein 2
VIPR1 vasoactive intestinal peptide receptor 1
WSCD1 WSC domain containing 1
ZFP36L2 ZFP36 ring finger protein-like 2
ZMAT4 zinc finger, matrin-type 4
ZNF137P zinc finger protein 137, pseudogene
ZNF536 zinc finger protein 536
ZNF614 zinc finger protein 614
ZNF750 zinc finger protein 750

decreased expression

Symbol Name
ADAM15 ADAM metallopeptidase domain 15
AFAP1 actin filament associated protein 1
AFF4 AF4/FMR2 family, member 4
AFG3L2 AFG3-like AAA ATPase 2
AHCTF1 AT hook containing transcription factor 1
ALG12 ALG12, alpha-1,6-mannosyltransferase
ALOX15 arachidonate 15-lipoxygenase
AP4M1 adaptor-related protein complex 4, mu 1 subunit
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
BHLHB9 basic helix-loop-helix domain containing, class B, 9
C19ORF40 chromosome 19 open reading frame 40
C1ORF159 chromosome 1 open reading frame 159
C22ORF29 chromosome 22 open reading frame 29
C5AR2 complement component 5a receptor 2
CCDC132 coiled-coil domain containing 132
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta
CENPJ centromere protein J
CENPT centromere protein T
CFD complement factor D (adipsin)
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DNM1 dynamin 1
EFNA3 ephrin-A3
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
FRK fyn-related Src family tyrosine kinase
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GBP2 guanylate binding protein 2, interferon-inducible
GID4 GID complex subunit 4
GLS2 glutaminase 2 (liver, mitochondrial)
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GPATCH3 G patch domain containing 3
HIST1H1B histone cluster 1, H1b
HOXB2 homeobox B2
HOXC5 homeobox C5
HSPA1L heat shock 70kDa protein 1-like
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IL12RB1 interleukin 12 receptor, beta 1
INO80D INO80 complex subunit D
KLHL21 kelch-like family member 21
KLK5 kallikrein-related peptidase 5
LIME1 Lck interacting transmembrane adaptor 1
LOC729164 hCG1732469
LRP3 low density lipoprotein receptor-related protein 3
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MBIP MAP3K12 binding inhibitory protein 1
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MCTP1 multiple C2 domains, transmembrane 1
NACA2 nascent polypeptide-associated complex alpha subunit 2
NPY5R neuropeptide Y receptor Y5
NUP62CL nucleoporin 62kDa C-terminal like
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
OXTR oxytocin receptor
PACS1 phosphofurin acidic cluster sorting protein 1
PAIP2B poly(A) binding protein interacting protein 2B
PANX1 pannexin 1
PCDHA9 protocadherin alpha 9
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene
PROL1 proline rich, lacrimal 1
RAB3A RAB3A, member RAS oncogene family
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RPL23AP32 ribosomal protein L23a pseudogene 32
RPS17P5 ribosomal protein S17 pseudogene 5
SCML2 sex comb on midleg-like 2 (Drosophila)
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SECTM1 secreted and transmembrane 1
SFRP5 secreted frizzled-related protein 5
SIGLEC15 sialic acid binding Ig-like lectin 15
SIRAL2 SIR2 antiphage like 2
SLC12A9 solute carrier family 12, member 9
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SNIP1 Smad nuclear interacting protein 1
SSFA2 sperm specific antigen 2
STARD5 StAR-related lipid transfer (START) domain containing 5
STON1 stonin 1
SUSD6 sushi domain containing 6
TCHH trichohyalin
TMEM183A transmembrane protein 183A
TOM1 target of myb1 (chicken)
TRIP10 thyroid hormone receptor interactor 10
TTBK2 tau tubulin kinase 2
TTC33 tetratricopeptide repeat domain 33
TWF2 twinfilin actin binding protein 2
UBQLN4 ubiquilin 4
USP27X ubiquitin specific peptidase 27, X-linked
VASH1 vasohibin 1
VEGFB vascular endothelial growth factor B
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
ZNF189 zinc finger protein 189
ZNF204P zinc finger protein 204, pseudogene
ZNF212 zinc finger protein 212
ZNF324 zinc finger protein 324
ZNF654 zinc finger protein 654