clobetasol-6095 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the clobetasol-6095 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ANGPT4 angiopoietin 4
ARTN artemin
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2
BCL6 B-cell CLL/lymphoma 6
C10ORF10 chromosome 10 open reading frame 10
C1QTNF1 C1q and tumor necrosis factor related protein 1
CACNG2 calcium channel, voltage-dependent, gamma subunit 2
CCDC181 coiled-coil domain containing 181
CCDC87 coiled-coil domain containing 87
CCL23 chemokine (C-C motif) ligand 23
CCZ1 CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae)
CDC14A cell division cycle 14A
CDHR2 cadherin-related family member 2
CDRT1 CMT1A duplicated region transcript 1
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
CPEB1 cytoplasmic polyadenylation element binding protein 1
CT55 cancer/testis antigen 55
CTSZ cathepsin Z
DCN decorin
DGCR2 DiGeorge syndrome critical region gene 2
DHRS12 dehydrogenase/reductase (SDR family) member 12
DNM3 dynamin 3
EMP1 epithelial membrane protein 1
FAM124B family with sequence similarity 124B
FAM13A family with sequence similarity 13, member A
FKRP fukutin related protein
FLJ22184
FRZB frizzled-related protein
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
GPR15 G protein-coupled receptor 15
GRIA4 glutamate receptor, ionotropic, AMPA 4
GRK4 G protein-coupled receptor kinase 4
GRM1 glutamate receptor, metabotropic 1
HGFAC HGF activator
HIST1H4A histone cluster 1, H4a
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
IGF2-AS IGF2 antisense RNA
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
ITM2C integral membrane protein 2C
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KLHL25 kelch-like family member 25
LLGL1 lethal giant larvae homolog 1 (Drosophila)
LOXL2 lysyl oxidase-like 2
LY86 lymphocyte antigen 86
LY9 lymphocyte antigen 9
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAML3 mastermind-like 3 (Drosophila)
MAOA monoamine oxidase A
MAPK8 mitogen-activated protein kinase 8
MEF2D myocyte enhancer factor 2D
MYL10 myosin, light chain 10, regulatory
NCF2 neutrophil cytosolic factor 2
NPAS3 neuronal PAS domain protein 3
NPPA natriuretic peptide A
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PKNOX1 PBX/knotted 1 homeobox 1
PLA2G1B phospholipase A2, group IB (pancreas)
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PPP1R12B protein phosphatase 1, regulatory subunit 12B
PRB1 proline-rich protein BstNI subfamily 1
PROX1 prospero homeobox 1
PSCA prostate stem cell antigen
PSG11 pregnancy specific beta-1-glycoprotein 11
PTPN1 protein tyrosine phosphatase, non-receptor type 1
PTPRB protein tyrosine phosphatase, receptor type, B
RAMP2 receptor (G protein-coupled) activity modifying protein 2
RELN reelin
RNF122 ring finger protein 122
RPS4Y1 ribosomal protein S4, Y-linked 1
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6
S100A8 S100 calcium binding protein A8
SAMD9 sterile alpha motif domain containing 9
SEC14L2 SEC14-like 2 (S. cerevisiae)
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SHMT1 serine hydroxymethyltransferase 1 (soluble)
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SMAD6 SMAD family member 6
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SPINK5 serine peptidase inhibitor, Kazal type 5
SPTB spectrin, beta, erythrocytic
SRD5A2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
TCP11L1 t-complex 11, testis-specific-like 1
THAP3 THAP domain containing, apoptosis associated protein 3
THSD4 thrombospondin, type I, domain containing 4
TIAL1 TIA1 cytotoxic granule-associated RNA binding protein-like 1
TK2 thymidine kinase 2, mitochondrial
TLE4 transducin-like enhancer of split 4
TTC38 tetratricopeptide repeat domain 38
UTY ubiquitously transcribed tetratricopeptide repeat containing, Y-linked
VIPR1 vasoactive intestinal peptide receptor 1
XYLB xylulokinase homolog (H. influenzae)
YPEL1 yippee-like 1 (Drosophila)
ZFP64 ZFP64 zinc finger protein
ZNF155 zinc finger protein 155
ZNF442 zinc finger protein 442
ZSCAN32 zinc finger and SCAN domain containing 32

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
ADCY6 adenylate cyclase 6
ALPK1 alpha-kinase 1
ANP32A-IT1 ANP32A intronic transcript 1
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
BCAS1 breast carcinoma amplified sequence 1
BFSP1 beaded filament structural protein 1, filensin
C1QTNF3 C1q and tumor necrosis factor related protein 3
C2ORF27A chromosome 2 open reading frame 27A
CEMIP cell migration inducing protein, hyaluronan binding
CEP170B centrosomal protein 170B
CGREF1 cell growth regulator with EF-hand domain 1
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
CLCN5 chloride channel, voltage-sensitive 5
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
DENND5A DENN/MADD domain containing 5A
DSE dermatan sulfate epimerase
ELSPBP1 epididymal sperm binding protein 1
ERMAP erythroblast membrane-associated protein (Scianna blood group)
FAAH fatty acid amide hydrolase
FAM110B family with sequence similarity 110, member B
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
FMOD fibromodulin
GATA4 GATA binding protein 4
GRAMD1C GRAM domain containing 1C
GUSBP3 glucuronidase, beta pseudogene 3
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HOXA4 homeobox A4
HOXB2 homeobox B2
HOXC8 homeobox C8
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
IFI35 interferon-induced protein 35
IGFBP6 insulin-like growth factor binding protein 6
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
LIG4 ligase IV, DNA, ATP-dependent
LIN7A lin-7 homolog A (C. elegans)
LOXL3 lysyl oxidase-like 3
LTBP2 latent transforming growth factor beta binding protein 2
LZTS3 leucine zipper, putative tumor suppressor family member 3
MATK megakaryocyte-associated tyrosine kinase
MGC12488
NFE2L3 nuclear factor, erythroid 2-like 3
NME5 NME/NM23 family member 5
NOL10 nucleolar protein 10
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PCDHA6 protocadherin alpha 6
PCDHB3 protocadherin beta 3
PDE12 phosphodiesterase 12
PER3 period circadian clock 3
PLA2G15 phospholipase A2, group XV
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6
POLH polymerase (DNA directed), eta
POM121 POM121 transmembrane nucleoporin
PRMT7 protein arginine methyltransferase 7
PRPH peripherin
PRR4 proline rich 4 (lacrimal)
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAD54L2 RAD54-like 2 (S. cerevisiae)
RAPSN receptor-associated protein of the synapse
RFXAP regulatory factor X-associated protein
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RLN1 relaxin 1
RPL23AP32 ribosomal protein L23a pseudogene 32
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
S100A9 S100 calcium binding protein A9
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SEMA6D sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
SENP7 SUMO1/sentrin specific peptidase 7
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SLC12A8 solute carrier family 12, member 8
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SLPI secretory leukocyte peptidase inhibitor
SPAG7 sperm associated antigen 7
STEAP1 six transmembrane epithelial antigen of the prostate 1
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
TAOK1 TAO kinase 1
TICAM1 toll-like receptor adaptor molecule 1
TMEM158 transmembrane protein 158 (gene/pseudogene)
TMEM209 transmembrane protein 209
TMEM242 transmembrane protein 242
TMEM254 transmembrane protein 254
TMEM53 transmembrane protein 53
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TSC22D4 TSC22 domain family, member 4
TUBG2 tubulin, gamma 2
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
ZBTB22 zinc finger and BTB domain containing 22
ZCCHC24 zinc finger, CCHC domain containing 24
ZNF16 zinc finger protein 16
ZNF324 zinc finger protein 324
ZNF516 zinc finger protein 516
ZNF573 zinc finger protein 573
ZNF711 zinc finger protein 711