clocortolone Gene Set
Genes
19 genes differentially expressed following the clocortolone small molecule perturbation from the LINCS L1000 CMAP Chemical Perturbation Consensus Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
DFFB
|
DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
|
5.40411
|
|
TRDN
|
triadin
|
4.20585
|
|
MYOT
|
myotilin
|
4.03966
|
|
CSRP3
|
cysteine and glycine-rich protein 3 (cardiac LIM protein)
|
3.96779
|
|
COQ8A
|
coenzyme Q8A
|
3.89742
|
|
MYH2
|
myosin, heavy chain 2, skeletal muscle, adult
|
3.86586
|
|
MYL2
|
myosin, light chain 2, regulatory, cardiac, slow
|
3.62968
|
|
CASQ1
|
calsequestrin 1 (fast-twitch, skeletal muscle)
|
3.62875
|
|
ACTA1
|
actin, alpha 1, skeletal muscle
|
3.44692
|
|
NEB
|
nebulin
|
3.26199
|
|
MYH7
|
myosin, heavy chain 7, cardiac muscle, beta
|
3.16541
|
|
SYNPO2L
|
synaptopodin 2-like
|
3.14204
|
|
PAQR5
|
progestin and adipoQ receptor family member V
|
3.13186
|
|
SIRT3
|
sirtuin 3
|
3.12663
|
|
KLHL41
|
kelch-like family member 41
|
3.09907
|
|
PPP1R3A
|
protein phosphatase 1, regulatory subunit 3A
|
3.03179
|
|
E2F2
|
E2F transcription factor 2
|
3.02071
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
STUB1
|
STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
|
-4.97026
|
|
CASP10
|
caspase 10, apoptosis-related cysteine peptidase
|
-4.45344
|
