| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the clofazimine-3239 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCD1 | ATP-binding cassette, sub-family D (ALD), member 1 |
| ACAA2 | acetyl-CoA acyltransferase 2 |
| AGER | advanced glycosylation end product-specific receptor |
| AGMAT | agmatine ureohydrolase (agmatinase) |
| AKAP8L | A kinase (PRKA) anchor protein 8-like |
| ALDOB | aldolase B, fructose-bisphosphate |
| AMPD1 | adenosine monophosphate deaminase 1 |
| APAF1 | apoptotic peptidase activating factor 1 |
| APOE | apolipoprotein E |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 |
| ATAT1 | alpha tubulin acetyltransferase 1 |
| ATP2B2 | ATPase, Ca++ transporting, plasma membrane 2 |
| BCL2L10 | BCL2-like 10 (apoptosis facilitator) |
| BGLAP | bone gamma-carboxyglutamate (gla) protein |
| C3 | complement component 3 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase |
| CCPG1 | cell cycle progression 1 |
| CD58 | CD58 molecule |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 |
| DCN | decorin |
| DIO2 | deiodinase, iodothyronine, type II |
| DMP1 | dentin matrix acidic phosphoprotein 1 |
| DNAI2 | dynein, axonemal, intermediate chain 2 |
| DNAJB12 | DnaJ (Hsp40) homolog, subfamily B, member 12 |
| DNAJB5 | DnaJ (Hsp40) homolog, subfamily B, member 5 |
| DOCK9 | dedicator of cytokinesis 9 |
| EFR3B | EFR3 homolog B (S. cerevisiae) |
| ESR1 | estrogen receptor 1 |
| FAM13C | family with sequence similarity 13, member C |
| FCMR | Fc fragment of IgM receptor |
| FGFR1 | fibroblast growth factor receptor 1 |
| FH | fumarate hydratase |
| FRMD4A | FERM domain containing 4A |
| GABBR2 | gamma-aminobutyric acid (GABA) B receptor, 2 |
| GHRHR | growth hormone releasing hormone receptor |
| GK | glycerol kinase |
| GPR182 | G protein-coupled receptor 182 |
| GRM7 | glutamate receptor, metabotropic 7 |
| GSK3A | glycogen synthase kinase 3 alpha |
| HCRTR2 | hypocretin (orexin) receptor 2 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 |
| HIPK3 | homeodomain interacting protein kinase 3 |
| HIST1H2BO | histone cluster 1, H2bo |
| IHH | indian hedgehog |
| JMJD6 | jumonji domain containing 6 |
| KANSL3 | KAT8 regulatory NSL complex subunit 3 |
| KIR2DL1 | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1 |
| LARP7 | La ribonucleoprotein domain family, member 7 |
| LDLRAD4 | low density lipoprotein receptor class A domain containing 4 |
| LMNA | lamin A/C |
| LSP1 | lymphocyte-specific protein 1 |
| MAGEA5 | melanoma antigen family A5 |
| MAN2A2 | mannosidase, alpha, class 2A, member 2 |
| MAP2K7 | mitogen-activated protein kinase kinase 7 |
| MAPK10 | mitogen-activated protein kinase 10 |
| METTL7A | methyltransferase like 7A |
| MOGAT2 | monoacylglycerol O-acyltransferase 2 |
| MR1 | major histocompatibility complex, class I-related |
| MTA1 | metastasis associated 1 |
| MYL10 | myosin, light chain 10, regulatory |
| NELL2 | NEL-like 2 (chicken) |
| NFATC1 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 |
| NPPA | natriuretic peptide A |
| OAZ3 | ornithine decarboxylase antizyme 3 |
| OR1D2 | olfactory receptor, family 1, subfamily D, member 2 |
| OXCT2 | 3-oxoacid CoA transferase 2 |
| PLAG1 | pleiomorphic adenoma gene 1 |
| PLAGL1 | pleiomorphic adenoma gene-like 1 |
| POU2F2 | POU class 2 homeobox 2 |
| PPP1R14D | protein phosphatase 1, regulatory (inhibitor) subunit 14D |
| PRAMEF11 | PRAME family member 11 |
| PRSS2 | protease, serine, 2 (trypsin 2) |
| RAC2 | ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 |
| RHOBTB2 | Rho-related BTB domain containing 2 |
| RIMS3 | regulating synaptic membrane exocytosis 3 |
| RMND5A | required for meiotic nuclear division 5 homolog A (S. cerevisiae) |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 |
| SAMD4A | sterile alpha motif domain containing 4A |
| SCARA3 | scavenger receptor class A, member 3 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 |
| SIRT5 | sirtuin 5 |
| SIX3 | SIX homeobox 3 |
| SLC24A1 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 |
| SLCO2A1 | solute carrier organic anion transporter family, member 2A1 |
| SMAD6 | SMAD family member 6 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) |
| SOCS7 | suppressor of cytokine signaling 7 |
| SORBS1 | sorbin and SH3 domain containing 1 |
| TEX40 | testis expressed 40 |
| TGFB2 | transforming growth factor, beta 2 |
| THPO | thrombopoietin |
| TLK1 | tousled-like kinase 1 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 |
| WNT2B | wingless-type MMTV integration site family, member 2B |
| ZNF384 | zinc finger protein 384 |
| ZNF783 | zinc finger family member 783 |
| Symbol | Name |
|---|---|
| ABCA12 | ATP-binding cassette, sub-family A (ABC1), member 12 |
| ARHGAP4 | Rho GTPase activating protein 4 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) |
| BTF3P11 | basic transcription factor 3 pseudogene 11 |
| C14ORF105 | chromosome 14 open reading frame 105 |
| C1ORF54 | chromosome 1 open reading frame 54 |
| C2ORF54 | chromosome 2 open reading frame 54 |
| CACNA1H | calcium channel, voltage-dependent, T type, alpha 1H subunit |
| CAPG | capping protein (actin filament), gelsolin-like |
| CARD8 | caspase recruitment domain family, member 8 |
| CASP3 | caspase 3, apoptosis-related cysteine peptidase |
| CBR4 | carbonyl reductase 4 |
| CCBL1 | cysteine conjugate-beta lyase, cytoplasmic |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain |
| CES1 | carboxylesterase 1 |
| CFAP69 | cilia and flagella associated protein 69 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 |
| CLSTN2 | calsyntenin 2 |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| CNR2 | cannabinoid receptor 2 (macrophage) |
| CRYGC | crystallin, gamma C |
| CTNNBIP1 | catenin, beta interacting protein 1 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 |
| DYSF | dysferlin |
| DZANK1 | double zinc ribbon and ankyrin repeat domains 1 |
| EMID1 | EMI domain containing 1 |
| FADS2 | fatty acid desaturase 2 |
| FLT4 | fms-related tyrosine kinase 4 |
| FURIN | furin (paired basic amino acid cleaving enzyme) |
| GABRA2 | gamma-aminobutyric acid (GABA) A receptor, alpha 2 |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GAMT | guanidinoacetate N-methyltransferase |
| GEMIN8 | gem (nuclear organelle) associated protein 8 |
| GIF | gastric intrinsic factor (vitamin B synthesis) |
| GPC3 | glypican 3 |
| HIST1H2AL | histone cluster 1, H2al |
| HLA-DMA | major histocompatibility complex, class II, DM alpha |
| HMOX1 | heme oxygenase 1 |
| HNRNPA3P1 | heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 |
| HOXC5 | homeobox C5 |
| IFT140 | intraflagellar transport 140 |
| IL15RA | interleukin 15 receptor, alpha |
| IRAK4 | interleukin-1 receptor-associated kinase 4 |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KIF13B | kinesin family member 13B |
| KLF7 | Kruppel-like factor 7 (ubiquitous) |
| LAX1 | lymphocyte transmembrane adaptor 1 |
| LDHB | lactate dehydrogenase B |
| LHX6 | LIM homeobox 6 |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) |
| LOC100286895 | cell division cycle 27 homolog pseudogene |
| LYZ | lysozyme |
| MATK | megakaryocyte-associated tyrosine kinase |
| MLLT4-AS1 | MLLT4 antisense RNA 1 (head to head) |
| NIPAL2 | NIPA-like domain containing 2 |
| NLGN1 | neuroligin 1 |
| OLFML2A | olfactomedin-like 2A |
| PDGFRL | platelet-derived growth factor receptor-like |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| PMCH | pro-melanin-concentrating hormone |
| PROS1 | protein S (alpha) |
| QPCTL | glutaminyl-peptide cyclotransferase-like |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RAPSN | receptor-associated protein of the synapse |
| REM1 | RAS (RAD and GEM)-like GTP-binding 1 |
| RNF121 | ring finger protein 121 |
| RNF39 | ring finger protein 39 |
| RNPEPL1 | arginyl aminopeptidase (aminopeptidase B)-like 1 |
| RPS6KA4 | ribosomal protein S6 kinase, 90kDa, polypeptide 4 |
| SAMD9 | sterile alpha motif domain containing 9 |
| SECTM1 | secreted and transmembrane 1 |
| SLC22A18AS | solute carrier family 22 (organic cation transporter), member 18 antisense |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 |
| SNAPC2 | small nuclear RNA activating complex, polypeptide 2, 45kDa |
| SPIDR | scaffolding protein involved in DNA repair |
| STAB2 | stabilin 2 |
| STX1A | syntaxin 1A (brain) |
| TCTN1 | tectonic family member 1 |
| TDRD1 | tudor domain containing 1 |
| THNSL1 | threonine synthase-like 1 (S. cerevisiae) |
| TMEM212 | transmembrane protein 212 |
| TMEM254 | transmembrane protein 254 |
| TNS2 | tensin 2 |
| TRIM21 | tripartite motif containing 21 |
| TUT1 | terminal uridylyl transferase 1, U6 snRNA-specific |
| UNC93B1 | unc-93 homolog B1 (C. elegans) |
| UPK2 | uroplakin 2 |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| VPS39 | vacuolar protein sorting 39 homolog (S. cerevisiae) |
| WDR62 | WD repeat domain 62 |
| ZBTB48 | zinc finger and BTB domain containing 48 |
| ZBTB6 | zinc finger and BTB domain containing 6 |
| ZNF250 | zinc finger protein 250 |
| ZNF480 | zinc finger protein 480 |
| ZNF668 | zinc finger protein 668 |
| ZNF696 | zinc finger protein 696 |
