| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the clofazimine-4682 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAM11 | ADAM metallopeptidase domain 11 |
| ADGRG1 | adhesion G protein-coupled receptor G1 |
| ADRA1A | adrenoceptor alpha 1A |
| AIF1 | allograft inflammatory factor 1 |
| AKAP17A | A kinase (PRKA) anchor protein 17A |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 |
| ASPHD1 | aspartate beta-hydroxylase domain containing 1 |
| ATP10B | ATPase, class V, type 10B |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 |
| ATXN2L | ataxin 2-like |
| B9D1 | B9 protein domain 1 |
| BBC3 | BCL2 binding component 3 |
| BMP7 | bone morphogenetic protein 7 |
| C10ORF10 | chromosome 10 open reading frame 10 |
| C2ORF27A | chromosome 2 open reading frame 27A |
| C4BPA | complement component 4 binding protein, alpha |
| C9ORF9 | chromosome 9 open reading frame 9 |
| CA5B | carbonic anhydrase VB, mitochondrial |
| CACYBP | calcyclin binding protein |
| CCNG2 | cyclin G2 |
| CD53 | CD53 molecule |
| CD79B | CD79b molecule, immunoglobulin-associated beta |
| CDH15 | cadherin 15, type 1, M-cadherin (myotubule) |
| CDK13 | cyclin-dependent kinase 13 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CRELD1 | cysteine-rich with EGF-like domains 1 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 |
| DBNDD1 | dysbindin (dystrobrevin binding protein 1) domain containing 1 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DENND3 | DENN/MADD domain containing 3 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 |
| DOCK10 | dedicator of cytokinesis 10 |
| EGFL7 | EGF-like-domain, multiple 7 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 |
| EPHA1 | EPH receptor A1 |
| EPS8L1 | EPS8-like 1 |
| FLJ42627 | uncharacterized LOC645644 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) |
| GAB1 | GRB2-associated binding protein 1 |
| GGA3 | golgi-associated, gamma adaptin ear containing, ARF binding protein 3 |
| GP5 | glycoprotein V (platelet) |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HTR7 | 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled |
| IFFO1 | intermediate filament family orphan 1 |
| IFT27 | intraflagellar transport 27 |
| IRF5 | interferon regulatory factor 5 |
| KCTD13 | potassium channel tetramerization domain containing 13 |
| KDM6B | lysine (K)-specific demethylase 6B |
| KLF4 | Kruppel-like factor 4 (gut) |
| LGALS14 | lectin, galactoside-binding, soluble, 14 |
| LIMD2 | LIM domain containing 2 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 |
| MAP1B | microtubule-associated protein 1B |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MOCS1 | molybdenum cofactor synthesis 1 |
| MVD | mevalonate (diphospho) decarboxylase |
| NEB | nebulin |
| NF1 | neurofibromin 1 |
| NPC1 | Niemann-Pick disease, type C1 |
| PAX2 | paired box 2 |
| PCYT1A | phosphate cytidylyltransferase 1, choline, alpha |
| PDE2A | phosphodiesterase 2A, cGMP-stimulated |
| PER1 | period circadian clock 1 |
| PITX1 | paired-like homeodomain 1 |
| PLXNB3 | plexin B3 |
| POU6F1 | POU class 6 homeobox 1 |
| PREX2 | phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 |
| PRKCA | protein kinase C, alpha |
| PRPH | peripherin |
| PTBP3 | polypyrimidine tract binding protein 3 |
| PVR | poliovirus receptor |
| RAD51D | RAD51 paralog D |
| RB1 | retinoblastoma 1 |
| RNASE4 | ribonuclease, RNase A family, 4 |
| RNF6 | ring finger protein (C3H2C3 type) 6 |
| RPS14 | ribosomal protein S14 |
| RUNX1 | runt-related transcription factor 1 |
| SDF2L1 | stromal cell-derived factor 2-like 1 |
| SERHL2 | serine hydrolase-like 2 |
| SETX | senataxin |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SMAD3 | SMAD family member 3 |
| ST3GAL2 | ST3 beta-galactoside alpha-2,3-sialyltransferase 2 |
| TBX1 | T-box 1 |
| TFEB | transcription factor EB |
| TGFA | transforming growth factor, alpha |
| THOC5 | THO complex 5 |
| TPP1 | tripeptidyl peptidase I |
| UST | uronyl-2-sulfotransferase |
| VASH1 | vasohibin 1 |
| WHSC1 | Wolf-Hirschhorn syndrome candidate 1 |
| WT1-AS | WT1 antisense RNA |
| ZFP36L1 | ZFP36 ring finger protein-like 1 |
| ZNF165 | zinc finger protein 165 |
| ZNF391 | zinc finger protein 391 |
| ZNF821 | zinc finger protein 821 |
| Symbol | Name |
|---|---|
| ABCG2 | ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) |
| ADAM23 | ADAM metallopeptidase domain 23 |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| ATP1A3 | ATPase, Na+/K+ transporting, alpha 3 polypeptide |
| C1ORF105 | chromosome 1 open reading frame 105 |
| C7ORF69 | chromosome 7 open reading frame 69 |
| CAPN5 | calpain 5 |
| CCDC132 | coiled-coil domain containing 132 |
| CD101 | CD101 molecule |
| CD79A | CD79a molecule, immunoglobulin-associated alpha |
| CELA2A | chymotrypsin-like elastase family, member 2A |
| CGREF1 | cell growth regulator with EF-hand domain 1 |
| CHRDL1 | chordin-like 1 |
| CIDEB | cell death-inducing DFFA-like effector b |
| CISH | cytokine inducible SH2-containing protein |
| COL4A3BP | collagen, type IV, alpha 3 (Goodpasture antigen) binding protein |
| COLGALT2 | collagen beta(1-O)galactosyltransferase 2 |
| CRYGC | crystallin, gamma C |
| CSRNP3 | cysteine-serine-rich nuclear protein 3 |
| CYP2J2 | cytochrome P450, family 2, subfamily J, polypeptide 2 |
| CYSLTR1 | cysteinyl leukotriene receptor 1 |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 |
| EYA4 | EYA transcriptional coactivator and phosphatase 4 |
| FAM13C | family with sequence similarity 13, member C |
| FAM186A | family with sequence similarity 186, member A |
| FAM212B | family with sequence similarity 212, member B |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FOXN2 | forkhead box N2 |
| GIF | gastric intrinsic factor (vitamin B synthesis) |
| GMPR | guanosine monophosphate reductase |
| GNG3 | guanine nucleotide binding protein (G protein), gamma 3 |
| GSTCD | glutathione S-transferase, C-terminal domain containing |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| GUCY1A2 | guanylate cyclase 1, soluble, alpha 2 |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H3I | histone cluster 1, H3i |
| HIST1H4C | histone cluster 1, H4c |
| HMOX1 | heme oxygenase 1 |
| HOXC10 | homeobox C10 |
| HSD17B8 | hydroxysteroid (17-beta) dehydrogenase 8 |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| IFT140 | intraflagellar transport 140 |
| IGKV3-20 | immunoglobulin kappa variable 3-20 |
| ITGA10 | integrin, alpha 10 |
| KIAA1456 | KIAA1456 |
| KIFC1 | kinesin family member C1 |
| KRT20 | keratin 20, type I |
| KRT31 | keratin 31, type I |
| LIG4 | ligase IV, DNA, ATP-dependent |
| LOC257152 | uncharacterized LOC257152 |
| LPAR4 | lysophosphatidic acid receptor 4 |
| LRRK1 | leucine-rich repeat kinase 1 |
| LYPD3 | LY6/PLAUR domain containing 3 |
| MC1R | melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| MRPL41 | mitochondrial ribosomal protein L41 |
| MUC3A | mucin 3A, cell surface associated |
| NABP1 | nucleic acid binding protein 1 |
| NCS1 | neuronal calcium sensor 1 |
| NDP | Norrie disease (pseudoglioma) |
| NEUROD1 | neuronal differentiation 1 |
| NME5 | NME/NM23 family member 5 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 |
| NUP62CL | nucleoporin 62kDa C-terminal like |
| OCA2 | oculocutaneous albinism II |
| OLFM4 | olfactomedin 4 |
| OR1G1 | olfactory receptor, family 1, subfamily G, member 1 |
| PDE11A | phosphodiesterase 11A |
| PDE6B | phosphodiesterase 6B, cGMP-specific, rod, beta |
| PDE6C | phosphodiesterase 6C, cGMP-specific, cone, alpha prime |
| PMCHL1 | pro-melanin-concentrating hormone-like 1, pseudogene |
| PRB3 | proline-rich protein BstNI subfamily 3 |
| QPCTL | glutaminyl-peptide cyclotransferase-like |
| RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 |
| RARS | arginyl-tRNA synthetase |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 |
| RIBC2 | RIB43A domain with coiled-coils 2 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RPRM | reprimo, TP53 dependent G2 arrest mediator candidate |
| SCD5 | stearoyl-CoA desaturase 5 |
| SCG2 | secretogranin II |
| SFTPA2 | surfactant protein A2 |
| SGK2 | serum/glucocorticoid regulated kinase 2 |
| SH2D2A | SH2 domain containing 2A |
| SLC17A2 | solute carrier family 17, member 2 |
| SLC18A2 | solute carrier family 18 (vesicular monoamine transporter), member 2 |
| SLC9A3 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 |
| SNORA21 | small nucleolar RNA, H/ACA box 21 |
| SPTBN2 | spectrin, beta, non-erythrocytic 2 |
| STEAP4 | STEAP family member 4 |
| TMEM212 | transmembrane protein 212 |
| TXNIP | thioredoxin interacting protein |
| VSIG10 | V-set and immunoglobulin domain containing 10 |
| WDR62 | WD repeat domain 62 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF480 | zinc finger protein 480 |
| ZNF76 | zinc finger protein 76 |
| ZNF770 | zinc finger protein 770 |
