| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the clofazimine-5277 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACAA2 | acetyl-CoA acyltransferase 2 |
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| AIRE | autoimmune regulator |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| APOE | apolipoprotein E |
| ARID4B | AT rich interactive domain 4B (RBP1-like) |
| ARVCF | armadillo repeat gene deleted in velocardiofacial syndrome |
| ATAT1 | alpha tubulin acetyltransferase 1 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic |
| C18ORF25 | chromosome 18 open reading frame 25 |
| C19ORF66 | chromosome 19 open reading frame 66 |
| CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase |
| CCL27 | chemokine (C-C motif) ligand 27 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHRNE | cholinergic receptor, nicotinic, epsilon (muscle) |
| CHST5 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5 |
| CLDN11 | claudin 11 |
| CNTN1 | contactin 1 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DEFA4 | defensin, alpha 4, corticostatin |
| DMP1 | dentin matrix acidic phosphoprotein 1 |
| DOK2 | docking protein 2, 56kDa |
| DPF1 | D4, zinc and double PHD fingers family 1 |
| DRICH1 | aspartate-rich 1 |
| EFR3B | EFR3 homolog B (S. cerevisiae) |
| EHBP1L1 | EH domain binding protein 1-like 1 |
| EPX | eosinophil peroxidase |
| ETV5 | ets variant 5 |
| EVI5 | ecotropic viral integration site 5 |
| FOXG1 | forkhead box G1 |
| FRMD4B | FERM domain containing 4B |
| FYN | FYN proto-oncogene, Src family tyrosine kinase |
| GM2A | GM2 ganglioside activator |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A |
| HNF1B | HNF1 homeobox B |
| HOXC13 | homeobox C13 |
| INHBE | inhibin, beta E |
| IRS2 | insulin receptor substrate 2 |
| ITGB5 | integrin, beta 5 |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 |
| KCNQ2 | potassium channel, voltage gated KQT-like subfamily Q, member 2 |
| KIR2DS4 | killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 4 |
| KRT83 | keratin 83, type II |
| LAIR1 | leukocyte-associated immunoglobulin-like receptor 1 |
| LINC00260 | long intergenic non-protein coding RNA 260 |
| LLPH | LLP homolog, long-term synaptic facilitation (Aplysia) |
| LRCH4 | leucine-rich repeats and calponin homology (CH) domain containing 4 |
| LUZP4 | leucine zipper protein 4 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAML3 | mastermind-like 3 (Drosophila) |
| MAN1A2 | mannosidase, alpha, class 1A, member 2 |
| MEF2D | myocyte enhancer factor 2D |
| MIIP | migration and invasion inhibitory protein |
| MPZL1 | myelin protein zero-like 1 |
| MSR1 | macrophage scavenger receptor 1 |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa |
| PAX5 | paired box 5 |
| PLAC4 | placenta-specific 4 |
| PRDX2 | peroxiredoxin 2 |
| PSG4 | pregnancy specific beta-1-glycoprotein 4 |
| RAB6A | RAB6A, member RAS oncogene family |
| RGS12 | regulator of G-protein signaling 12 |
| RHBG | Rh family, B glycoprotein (gene/pseudogene) |
| RIC3 | RIC3 acetylcholine receptor chaperone |
| RND2 | Rho family GTPase 2 |
| RPL35A | ribosomal protein L35a |
| RUNX1 | runt-related transcription factor 1 |
| SBF1 | SET binding factor 1 |
| SCN11A | sodium channel, voltage gated, type XI alpha subunit |
| SHOX2 | short stature homeobox 2 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 |
| SLC43A1 | solute carrier family 43 (amino acid system L transporter), member 1 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SNPH | syntaphilin |
| SPTB | spectrin, beta, erythrocytic |
| ST8SIA3 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 |
| SWAP70 | SWAP switching B-cell complex 70kDa subunit |
| TBC1D22A | TBC1 domain family, member 22A |
| TBC1D22B | TBC1 domain family, member 22B |
| TBX3 | T-box 3 |
| TBX5 | T-box 5 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) |
| TEF | thyrotrophic embryonic factor |
| TNPO2 | transportin 2 |
| TREM2 | triggering receptor expressed on myeloid cells 2 |
| TRIM29 | tripartite motif containing 29 |
| UBE3A | ubiquitin protein ligase E3A |
| VEGFB | vascular endothelial growth factor B |
| VN1R1 | vomeronasal 1 receptor 1 |
| WNT1 | wingless-type MMTV integration site family, member 1 |
| WNT8B | wingless-type MMTV integration site family, member 8B |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZXDB | zinc finger, X-linked, duplicated B |
| Symbol | Name |
|---|---|
| ALOX15 | arachidonate 15-lipoxygenase |
| ARC | activity-regulated cytoskeleton-associated protein |
| ARHGEF10L | Rho guanine nucleotide exchange factor (GEF) 10-like |
| ARMC4 | armadillo repeat containing 4 |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| ATG2A | autophagy related 2A |
| C2ORF27A | chromosome 2 open reading frame 27A |
| CCBL1 | cysteine conjugate-beta lyase, cytoplasmic |
| CCDC85C | coiled-coil domain containing 85C |
| CHRM3 | cholinergic receptor, muscarinic 3 |
| CLDN15 | claudin 15 |
| CLUHP3 | clustered mitochondria (cluA/CLU1) homolog pseudogene 3 |
| CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 |
| CRABP1 | cellular retinoic acid binding protein 1 |
| CUL9 | cullin 9 |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DMTN | dematin actin binding protein |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| DOK1 | docking protein 1, 62kDa (downstream of tyrosine kinase 1) |
| ECHDC3 | enoyl CoA hydratase domain containing 3 |
| EPHX2 | epoxide hydrolase 2, cytoplasmic |
| ERCC6 | excision repair cross-complementation group 6 |
| FBXL6 | F-box and leucine-rich repeat protein 6 |
| FGF23 | fibroblast growth factor 23 |
| FLJ22184 | |
| GAS2 | growth arrest-specific 2 |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GNAZ | guanine nucleotide binding protein (G protein), alpha z polypeptide |
| GPR19 | G protein-coupled receptor 19 |
| GPR85 | G protein-coupled receptor 85 |
| GTF2H4 | general transcription factor IIH, polypeptide 4, 52kDa |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HDAC11 | histone deacetylase 11 |
| HIST1H2BC | histone cluster 1, H2bc |
| HIST1H2BO | histone cluster 1, H2bo |
| HOXA4 | homeobox A4 |
| HSD17B14 | hydroxysteroid (17-beta) dehydrogenase 14 |
| KIAA0319L | KIAA0319-like |
| KIF5A | kinesin family member 5A |
| KLF7 | Kruppel-like factor 7 (ubiquitous) |
| KLHL25 | kelch-like family member 25 |
| LIN7A | lin-7 homolog A (C. elegans) |
| LMO2 | LIM domain only 2 (rhombotin-like 1) |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MAPKBP1 | mitogen-activated protein kinase binding protein 1 |
| MEFV | Mediterranean fever |
| MLYCD | malonyl-CoA decarboxylase |
| MMP3 | matrix metallopeptidase 3 |
| MPP3 | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) |
| MTCP1 | mature T-cell proliferation 1 |
| MYOZ3 | myozenin 3 |
| NME5 | NME/NM23 family member 5 |
| NOS1AP | nitric oxide synthase 1 (neuronal) adaptor protein |
| NUDT18 | nudix (nucleoside diphosphate linked moiety X)-type motif 18 |
| PCDHB13 | protocadherin beta 13 |
| PDE8B | phosphodiesterase 8B |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PLA2G3 | phospholipase A2, group III |
| PLEKHA2 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 |
| POM121 | POM121 transmembrane nucleoporin |
| PPP1R9A | protein phosphatase 1, regulatory subunit 9A |
| PRODH | proline dehydrogenase (oxidase) 1 |
| PRSS53 | protease, serine, 53 |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RAI2 | retinoic acid induced 2 |
| RASSF2 | Ras association (RalGDS/AF-6) domain family member 2 |
| RPAP1 | RNA polymerase II associated protein 1 |
| RPGRIP1L | RPGRIP1-like |
| S100A7 | S100 calcium binding protein A7 |
| SAMD9 | sterile alpha motif domain containing 9 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 |
| SIX1 | SIX homeobox 1 |
| SLC22A18AS | solute carrier family 22 (organic cation transporter), member 18 antisense |
| SLC9A5 | solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| SRPX | sushi-repeat containing protein, X-linked |
| SSBP3 | single stranded DNA binding protein 3 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 |
| STIM1 | stromal interaction molecule 1 |
| SYNGR3 | synaptogyrin 3 |
| TAOK1 | TAO kinase 1 |
| TARP | TCR gamma alternate reading frame protein |
| TBC1D19 | TBC1 domain family, member 19 |
| THNSL1 | threonine synthase-like 1 (S. cerevisiae) |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) |
| TWISTNB | TWIST neighbor |
| TXNIP | thioredoxin interacting protein |
| TYRP1 | tyrosinase-related protein 1 |
| VAV1 | vav 1 guanine nucleotide exchange factor |
| YY2 | YY2 transcription factor |
| ZDHHC11 | zinc finger, DHHC-type containing 11 |
| ZFHX4 | zinc finger homeobox 4 |
| ZMAT5 | zinc finger, matrin-type 5 |
| ZNF204P | zinc finger protein 204, pseudogene |
| ZNF23 | zinc finger protein 23 |
| ZNF324 | zinc finger protein 324 |
| ZNF862 | zinc finger protein 862 |
