| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the clofazimine-5642 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCC9 | ATP-binding cassette, sub-family C (CFTR/MRP), member 9 |
| ACPP | acid phosphatase, prostate |
| ADAM12 | ADAM metallopeptidase domain 12 |
| AHI1 | Abelson helper integration site 1 |
| ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) |
| ANG | angiogenin, ribonuclease, RNase A family, 5 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 |
| ATF7IP | activating transcription factor 7 interacting protein |
| BMP8A | bone morphogenetic protein 8a |
| CA1 | carbonic anhydrase I |
| CAMSAP1 | calmodulin regulated spectrin-associated protein 1 |
| CARD14 | caspase recruitment domain family, member 14 |
| CDC42EP1 | CDC42 effector protein (Rho GTPase binding) 1 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CRHR2 | corticotropin releasing hormone receptor 2 |
| DFNB31 | deafness, autosomal recessive 31 |
| DGCR8 | DGCR8 microprocessor complex subunit |
| DOK2 | docking protein 2, 56kDa |
| DTX2 | deltex 2, E3 ubiquitin ligase |
| DVL3 | dishevelled segment polarity protein 3 |
| FCN2 | ficolin (collagen/fibrinogen domain containing lectin) 2 |
| GAS7 | growth arrest-specific 7 |
| GIMAP6 | GTPase, IMAP family member 6 |
| GPR153 | G protein-coupled receptor 153 |
| GRIA4 | glutamate receptor, ionotropic, AMPA 4 |
| GSPT1 | G1 to S phase transition 1 |
| HR | hair growth associated |
| IDUA | iduronidase, alpha-L- |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 |
| INPP4A | inositol polyphosphate-4-phosphatase, type I, 107kDa |
| KIR2DL1 | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1 |
| KRT20 | keratin 20, type I |
| LAMP1 | lysosomal-associated membrane protein 1 |
| LARP6 | La ribonucleoprotein domain family, member 6 |
| LGALS8 | lectin, galactoside-binding, soluble, 8 |
| LRCH4 | leucine-rich repeats and calponin homology (CH) domain containing 4 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 |
| MAOB | monoamine oxidase B |
| MAP4K2 | mitogen-activated protein kinase kinase kinase kinase 2 |
| MAPK10 | mitogen-activated protein kinase 10 |
| MBD3 | methyl-CpG binding domain protein 3 |
| MXD4 | MAX dimerization protein 4 |
| MYO1D | myosin ID |
| N4BP2L2 | NEDD4 binding protein 2-like 2 |
| N4BP3 | NEDD4 binding protein 3 |
| NAB2 | NGFI-A binding protein 2 (EGR1 binding protein 2) |
| NBL1 | neuroblastoma 1, DAN family BMP antagonist |
| NCR3 | natural cytotoxicity triggering receptor 3 |
| NDOR1 | NADPH dependent diflavin oxidoreductase 1 |
| NEK9 | NIMA-related kinase 9 |
| NOL12 | nucleolar protein 12 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| PALM | paralemmin |
| PBX2 | pre-B-cell leukemia homeobox 2 |
| PCDH12 | protocadherin 12 |
| PHF20L1 | PHD finger protein 20-like 1 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) |
| PLAU | plasminogen activator, urokinase |
| PLCD1 | phospholipase C, delta 1 |
| PLXDC1 | plexin domain containing 1 |
| POPDC3 | popeye domain containing 3 |
| PORCN | porcupine homolog (Drosophila) |
| PPARG | peroxisome proliferator-activated receptor gamma |
| PRDM1 | PR domain containing 1, with ZNF domain |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) |
| PYY | peptide YY |
| RAP1GAP | RAP1 GTPase activating protein |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 |
| RPL7 | ribosomal protein L7 |
| RPS6KA6 | ribosomal protein S6 kinase, 90kDa, polypeptide 6 |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SCUBE3 | signal peptide, CUB domain, EGF-like 3 |
| SDHD | succinate dehydrogenase complex, subunit D, integral membrane protein |
| SERPINI2 | serpin peptidase inhibitor, clade I (pancpin), member 2 |
| SLC10A1 | solute carrier family 10 (sodium/bile acid cotransporter), member 1 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SMG7-AS1 | SMG7 antisense RNA 1 |
| SMR3A | submaxillary gland androgen regulated protein 3A |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) |
| SSX1 | synovial sarcoma, X breakpoint 1 |
| STAC | SH3 and cysteine rich domain |
| STATH | statherin |
| STK11 | serine/threonine kinase 11 |
| TGFB2 | transforming growth factor, beta 2 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 |
| TK2 | thymidine kinase 2, mitochondrial |
| TLR2 | toll-like receptor 2 |
| TNC | tenascin C |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
| UBA7 | ubiquitin-like modifier activating enzyme 7 |
| VLDLR | very low density lipoprotein receptor |
| XAF1 | XIAP associated factor 1 |
| XPNPEP1 | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble |
| ZFP36L2 | ZFP36 ring finger protein-like 2 |
| ZMIZ2 | zinc finger, MIZ-type containing 2 |
| ZNF76 | zinc finger protein 76 |
| Symbol | Name |
|---|---|
| ADAP2 | ArfGAP with dual PH domains 2 |
| ADTRP | androgen-dependent TFPI-regulating protein |
| BET1L | Bet1 golgi vesicular membrane trafficking protein-like |
| BIRC7 | baculoviral IAP repeat containing 7 |
| C14ORF93 | chromosome 14 open reading frame 93 |
| C8ORF60 | chromosome 8 open reading frame 60 |
| CCDC121 | coiled-coil domain containing 121 |
| CCP110 | centriolar coiled coil protein 110kDa |
| CD82 | CD82 molecule |
| CFAP44 | cilia and flagella associated protein 44 |
| CIDEC | cell death-inducing DFFA-like effector c |
| CLGN | calmegin |
| CLIC2 | chloride intracellular channel 2 |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| COPG2IT1 | COPG2 imprinted transcript 1 (non-protein coding) |
| CRIP1 | cysteine-rich protein 1 (intestinal) |
| CTAGE1 | cutaneous T-cell lymphoma-associated antigen 1 |
| CTSF | cathepsin F |
| CXADR | coxsackie virus and adenovirus receptor |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| CYP4F11 | cytochrome P450, family 4, subfamily F, polypeptide 11 |
| DEAF1 | DEAF1 transcription factor |
| DIXDC1 | DIX domain containing 1 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| EFNA3 | ephrin-A3 |
| EIF5A2 | eukaryotic translation initiation factor 5A2 |
| EPHX2 | epoxide hydrolase 2, cytoplasmic |
| ETV6 | ets variant 6 |
| EXTL3 | exostosin-like glycosyltransferase 3 |
| FAM110B | family with sequence similarity 110, member B |
| FAM155A | family with sequence similarity 155, member A |
| GMPR | guanosine monophosphate reductase |
| GNA15 | guanine nucleotide binding protein (G protein), alpha 15 (Gq class) |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GPR27 | G protein-coupled receptor 27 |
| HAMP | hepcidin antimicrobial peptide |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 |
| HIST1H2BI | histone cluster 1, H2bi |
| HIST1H2BJ | histone cluster 1, H2bj |
| HMHB1 | histocompatibility (minor) HB-1 |
| HOXB2 | homeobox B2 |
| HOXC4 | homeobox C4 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 |
| HSPA1L | heat shock 70kDa protein 1-like |
| IGSF6 | immunoglobulin superfamily, member 6 |
| IQCC | IQ motif containing C |
| ISL1 | ISL LIM homeobox 1 |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KCNK12 | potassium channel, two pore domain subfamily K, member 12 |
| KCNN2 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 |
| LOC390998 | ribosomal protein L10 pseudogene |
| MRPL41 | mitochondrial ribosomal protein L41 |
| MTHFS | 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase) |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NLRX1 | NLR family member X1 |
| NME5 | NME/NM23 family member 5 |
| OR1D2 | olfactory receptor, family 1, subfamily D, member 2 |
| PARP12 | poly (ADP-ribose) polymerase family, member 12 |
| PCDHA5 | protocadherin alpha 5 |
| PDE12 | phosphodiesterase 12 |
| PDGFRL | platelet-derived growth factor receptor-like |
| POM121L2 | POM121 transmembrane nucleoporin-like 2 |
| PRAMEF11 | PRAME family member 11 |
| PRDM16 | PR domain containing 16 |
| PYCRL | pyrroline-5-carboxylate reductase-like |
| PYHIN1 | pyrin and HIN domain family, member 1 |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 |
| RNF121 | ring finger protein 121 |
| RRH | retinal pigment epithelium-derived rhodopsin homolog |
| SAG | S-antigen; retina and pineal gland (arrestin) |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SCML2 | sex comb on midleg-like 2 (Drosophila) |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SLC12A5 | solute carrier family 12 (potassium/chloride transporter), member 5 |
| SLC22A14 | solute carrier family 22, member 14 |
| SLC2A8 | solute carrier family 2 (facilitated glucose transporter), member 8 |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| SLC5A5 | solute carrier family 5 (sodium/iodide cotransporter), member 5 |
| SMARCD3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 |
| SULT4A1 | sulfotransferase family 4A, member 1 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TGFBR3 | transforming growth factor, beta receptor III |
| TRDMT1 | tRNA aspartic acid methyltransferase 1 |
| TXNIP | thioredoxin interacting protein |
| USP20 | ubiquitin specific peptidase 20 |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| YY2 | YY2 transcription factor |
| ZNF204P | zinc finger protein 204, pseudogene |
| ZNF226 | zinc finger protein 226 |
| ZNF286A | zinc finger protein 286A |
| ZNF350 | zinc finger protein 350 |
| ZNF480 | zinc finger protein 480 |
| ZNF484 | zinc finger protein 484 |
| ZNF573 | zinc finger protein 573 |
| ZNF701 | zinc finger protein 701 |
| ZNF747 | zinc finger protein 747 |
| ZNF750 | zinc finger protein 750 |
