clofibrate-444 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the clofibrate-444 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AK1 adenylate kinase 1
AKAP8L A kinase (PRKA) anchor protein 8-like
ALAD aminolevulinate dehydratase
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ASCL1 achaete-scute family bHLH transcription factor 1
ATF6 activating transcription factor 6
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1
AVL9 AVL9 homolog (S. cerevisiase)
BAHD1 bromo adjacent homology domain containing 1
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase)
BRCA1 breast cancer 1, early onset
BTBD2 BTB (POZ) domain containing 2
C14ORF1 chromosome 14 open reading frame 1
CAMK2G calcium/calmodulin-dependent protein kinase II gamma
CCDC85C coiled-coil domain containing 85C
CD5 CD5 molecule
CDC42EP2 CDC42 effector protein (Rho GTPase binding) 2
CDH15 cadherin 15, type 1, M-cadherin (myotubule)
CEP192 centrosomal protein 192kDa
CEP85 centrosomal protein 85kDa
CHAF1B chromatin assembly factor 1, subunit B (p60)
COX16 COX16 cytochrome c oxidase assembly homolog (S. cerevisiae)
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38
DIEXF digestive organ expansion factor homolog (zebrafish)
DNASE1L1 deoxyribonuclease I-like 1
ELMO2 engulfment and cell motility 2
EPS8L1 EPS8-like 1
EPX eosinophil peroxidase
ESR1 estrogen receptor 1
FANCF Fanconi anemia, complementation group F
FASTKD5 FAST kinase domains 5
FCHSD2 FCH and double SH3 domains 2
FOLR1 folate receptor 1 (adult)
GADD45B growth arrest and DNA-damage-inducible, beta
GLTSCR1 glioma tumor suppressor candidate region gene 1
GMEB2 glucocorticoid modulatory element binding protein 2
GOSR2 golgi SNAP receptor complex member 2
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GRPR gastrin-releasing peptide receptor
GSK3A glycogen synthase kinase 3 alpha
HBB hemoglobin, beta
HIST1H1C histone cluster 1, H1c
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa
HUS1 HUS1 checkpoint homolog (S. pombe)
ICA1 islet cell autoantigen 1, 69kDa
ICAM1 intercellular adhesion molecule 1
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
LBP lipopolysaccharide binding protein
LENEP lens epithelial protein
LMBR1L limb development membrane protein 1-like
MASP2 mannan-binding lectin serine peptidase 2
MBD3 methyl-CpG binding domain protein 3
NDRG4 NDRG family member 4
NKIRAS2 NFKB inhibitor interacting Ras-like 2
NOD1 nucleotide-binding oligomerization domain containing 1
NTRK3 neurotrophic tyrosine kinase, receptor, type 3
PARVA parvin, alpha
PHEX phosphate regulating endopeptidase homolog, X-linked
PKNOX2 PBX/knotted 1 homeobox 2
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit
POM121L2 POM121 transmembrane nucleoporin-like 2
POT1 protection of telomeres 1
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
RALGAPA1 Ral GTPase activating protein, alpha subunit 1 (catalytic)
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RBM5 RNA binding motif protein 5
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RPLP2 ribosomal protein, large, P2
RPS11 ribosomal protein S11
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
SH3GL3 SH3-domain GRB2-like 3
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter)
SLC38A7 solute carrier family 38, member 7
SLC45A2 solute carrier family 45, member 2
SLC6A13 solute carrier family 6 (neurotransmitter transporter), member 13
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SNORA21 small nucleolar RNA, H/ACA box 21
TBC1D16 TBC1 domain family, member 16
TCOF1 Treacher Collins-Franceschetti syndrome 1
TCTN1 tectonic family member 1
THOC1 THO complex 1
TRIM23 tripartite motif containing 23
TRMT1 tRNA methyltransferase 1 homolog (S. cerevisiae)
TTLL4 tubulin tyrosine ligase-like family member 4
USF2 upstream transcription factor 2, c-fos interacting
UTY ubiquitously transcribed tetratricopeptide repeat containing, Y-linked
WIZ widely interspaced zinc finger motifs
WTAP Wilms tumor 1 associated protein
YIPF2 Yip1 domain family, member 2
YLPM1 YLP motif containing 1
ZBTB40 zinc finger and BTB domain containing 40
ZNF219 zinc finger protein 219

decreased expression

Symbol Name
A4GNT alpha-1,4-N-acetylglucosaminyltransferase
ABLIM3 actin binding LIM protein family, member 3
ADAM30 ADAM metallopeptidase domain 30
AGPS alkylglycerone phosphate synthase
ALPK1 alpha-kinase 1
ANXA2P1 annexin A2 pseudogene 1
ARRB1 arrestin, beta 1
ASGR2 asialoglycoprotein receptor 2
ATG10 autophagy related 10
BHMT betaine--homocysteine S-methyltransferase
BIRC7 baculoviral IAP repeat containing 7
C16ORF59 chromosome 16 open reading frame 59
C5 complement component 5
C6 complement component 6
CCDC94 coiled-coil domain containing 94
CD177 CD177 molecule
CDH22 cadherin 22, type 2
CEP70 centrosomal protein 70kDa
CNPY3 canopy FGF signaling regulator 3
COL6A3 collagen, type VI, alpha 3
CORO7 coronin 7
CRYAB crystallin, alpha B
CXORF21 chromosome X open reading frame 21
CYB5R2 cytochrome b5 reductase 2
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DCPS decapping enzyme, scavenger
EGR2 early growth response 2
FGFBP1 fibroblast growth factor binding protein 1
FLCN folliculin
FSHB follicle stimulating hormone, beta polypeptide
FXYD5 FXYD domain containing ion transport regulator 5
GCKR glucokinase (hexokinase 4) regulator
GLDC glycine dehydrogenase (decarboxylating)
GMPPB GDP-mannose pyrophosphorylase B
GPC3 glypican 3
GPR176 G protein-coupled receptor 176
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HIST1H4J histone cluster 1, H4j
HPGDS hematopoietic prostaglandin D synthase
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IRS4 insulin receptor substrate 4
JAM2 junctional adhesion molecule 2
JRKL JRK-like
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
KCNJ14 potassium channel, inwardly rectifying subfamily J, member 14
KLHL3 kelch-like family member 3
LGALS13 lectin, galactoside-binding, soluble, 13
LOC257152 uncharacterized LOC257152
LOC729164 hCG1732469
MARC1 mitochondrial amidoxime reducing component 1
MEIS1 Meis homeobox 1
MRPL35 mitochondrial ribosomal protein L35
MTMR10 myotubularin related protein 10
MYL5 myosin, light chain 5, regulatory
NAA11 N(alpha)-acetyltransferase 11, NatA catalytic subunit
NAT9 N-acetyltransferase 9 (GCN5-related, putative)
NCALD neurocalcin delta
NDUFS7 NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase)
NIPAL2 NIPA-like domain containing 2
NOS2 nitric oxide synthase 2, inducible
NRSN2 neurensin 2
NUDT2 nudix (nucleoside diphosphate linked moiety X)-type motif 2
NUPL2 nucleoporin like 2
OR10J1 olfactory receptor, family 10, subfamily J, member 1
OR2S2 olfactory receptor, family 2, subfamily S, member 2 (gene/pseudogene)
OR5I1 olfactory receptor, family 5, subfamily I, member 1
OSGIN1 oxidative stress induced growth inhibitor 1
PICK1 protein interacting with PRKCA 1
PLEK2 pleckstrin 2
PODNL1 podocan-like 1
POP1 processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae)
PRODH proline dehydrogenase (oxidase) 1
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2
PVRIG poliovirus receptor related immunoglobulin domain containing
RGP1 RGP1 retrograde golgi transport homolog (S. cerevisiae)
S1PR4 sphingosine-1-phosphate receptor 4
SEC14L5 SEC14-like 5 (S. cerevisiae)
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SH2D2A SH2 domain containing 2A
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
SMO smoothened, frizzled class receptor
SOD3 superoxide dismutase 3, extracellular
SOX21 SRY (sex determining region Y)-box 21
SPP2 secreted phosphoprotein 2, 24kDa
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
STMN4 stathmin-like 4
TAAR2 trace amine associated receptor 2
TEX13B testis expressed 13B
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TMPRSS5 transmembrane protease, serine 5
TMSB15A thymosin beta 15a
TMSB4Y thymosin beta 4, Y-linked
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
UCP1 uncoupling protein 1 (mitochondrial, proton carrier)
VIM vimentin
ZNF74 zinc finger protein 74