clomifene-6648 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the clomifene-6648 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM22 ADAM metallopeptidase domain 22
ADAM7 ADAM metallopeptidase domain 7
AKAP13 A kinase (PRKA) anchor protein 13
ALDOB aldolase B, fructose-bisphosphate
BAIAP3 BAI1-associated protein 3
C2CD2L C2CD2-like
C8A complement component 8, alpha polypeptide
CACFD1 calcium channel flower domain containing 1
CACNG1 calcium channel, voltage-dependent, gamma subunit 1
CADM4 cell adhesion molecule 4
CAMKV CaM kinase-like vesicle-associated
CAPN3 calpain 3, (p94)
CBS cystathionine-beta-synthase
CD247 CD247 molecule
CDKL1 cyclin-dependent kinase-like 1 (CDC2-related kinase)
CEACAM3 carcinoembryonic antigen-related cell adhesion molecule 3
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
CLMN calmin (calponin-like, transmembrane)
CSF1 colony stimulating factor 1 (macrophage)
CXCR6 chemokine (C-X-C motif) receptor 6
DCHS2 dachsous cadherin-related 2
DDN dendrin
DDX28 DEAD (Asp-Glu-Ala-Asp) box polypeptide 28
DOK4 docking protein 4
DUOX2 dual oxidase 2
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2
EPS15L1 epidermal growth factor receptor pathway substrate 15-like 1
FBXO40 F-box protein 40
FGB fibrinogen beta chain
FGF18 fibroblast growth factor 18
FOS FBJ murine osteosarcoma viral oncogene homolog
GIP gastric inhibitory polypeptide
GJC2 gap junction protein, gamma 2, 47kDa
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
GPM6A glycoprotein M6A
GPNMB glycoprotein (transmembrane) nmb
HAAO 3-hydroxyanthranilate 3,4-dioxygenase
HBB hemoglobin, beta
HOXC5 homeobox C5
ICA1 islet cell autoantigen 1, 69kDa
ICOSLG inducible T-cell co-stimulator ligand
IL1RN interleukin 1 receptor antagonist
JAG1 jagged 1
KEL Kell blood group, metallo-endopeptidase
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2
KIAA1045 KIAA1045
KIR2DL1 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1
KLHL22 kelch-like family member 22
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LILRA2 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
LMNA lamin A/C
LOX lysyl oxidase
LRRN3 leucine rich repeat neuronal 3
MAG myelin associated glycoprotein
MAGEA5 melanoma antigen family A5
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
MORN1 MORN repeat containing 1
MT1M metallothionein 1M
MTMR7 myotubularin related protein 7
MYH8 myosin, heavy chain 8, skeletal muscle, perinatal
NCOR2 nuclear receptor corepressor 2
NOX1 NADPH oxidase 1
PALM paralemmin
PARP8 poly (ADP-ribose) polymerase family, member 8
PBOV1 prostate and breast cancer overexpressed 1
PCDHB13 protocadherin beta 13
PDCD6 programmed cell death 6
PDE11A phosphodiesterase 11A
PDIA2 protein disulfide isomerase family A, member 2
PROZ protein Z, vitamin K-dependent plasma glycoprotein
PTPN11 protein tyrosine phosphatase, non-receptor type 11
RDH8 retinol dehydrogenase 8 (all-trans)
RREB1 ras responsive element binding protein 1
SCN11A sodium channel, voltage gated, type XI alpha subunit
SLC10A2 solute carrier family 10 (sodium/bile acid cotransporter), member 2
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9
SMAD6 SMAD family member 6
SPANXC SPANX family, member C
SPARCL1 SPARC-like 1 (hevin)
SPO11 SPO11 meiotic protein covalently bound to DSB
SRD5A2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
SSX3 synovial sarcoma, X breakpoint 3
STMN4 stathmin-like 4
SULT1E1 sulfotransferase family 1E, estrogen-preferring, member 1
TBL1Y transducin (beta)-like 1, Y-linked
TCEAL2 transcription elongation factor A (SII)-like 2
TEF thyrotrophic embryonic factor
TLX3 T-cell leukemia homeobox 3
TMEM74B transmembrane protein 74B
TNS4 tensin 4
TSC22D3 TSC22 domain family, member 3
TSGA10 testis specific, 10
UPK2 uroplakin 2
WNT16 wingless-type MMTV integration site family, member 16
ZCCHC14 zinc finger, CCHC domain containing 14
ZNF688 zinc finger protein 688

decreased expression

Symbol Name
AAAS achalasia, adrenocortical insufficiency, alacrimia
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ATAD5 ATPase family, AAA domain containing 5
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
BATF3 basic leucine zipper transcription factor, ATF-like 3
BTF3P12 basic transcription factor 3 pseudogene 12
C17ORF75 chromosome 17 open reading frame 75
CBX4 chromobox homolog 4
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CLCN5 chloride channel, voltage-sensitive 5
CLDN1 claudin 1
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
CNGA1 cyclic nucleotide gated channel alpha 1
CNIH3 cornichon family AMPA receptor auxiliary protein 3
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
DENND4A DENN/MADD domain containing 4A
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DSPP dentin sialophosphoprotein
E2F8 E2F transcription factor 8
EFNA3 ephrin-A3
EMP3 epithelial membrane protein 3
EN2 engrailed homeobox 2
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
FKBP5 FK506 binding protein 5
FSTL3 follistatin-like 3 (secreted glycoprotein)
GDAP1 ganglioside induced differentiation associated protein 1
GEMIN8 gem (nuclear organelle) associated protein 8
GINS4 GINS complex subunit 4 (Sld5 homolog)
GSTCD glutathione S-transferase, C-terminal domain containing
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HAUS6 HAUS augmin-like complex, subunit 6
HDAC11 histone deacetylase 11
HDAC7 histone deacetylase 7
HIST1H1E histone cluster 1, H1e
HIST2H2AA3 histone cluster 2, H2aa3
HMOX1 heme oxygenase 1
HOXC8 homeobox C8
INO80D INO80 complex subunit D
KIAA0895 KIAA0895
KPTN kaptin (actin binding protein)
KRT8P12 keratin 8 pseudogene 12
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LMNB1 lamin B1
LMO7 LIM domain 7
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
MBTD1 mbt domain containing 1
MCC mutated in colorectal cancers
MED31 mediator complex subunit 31
MFHAS1 malignant fibrous histiocytoma amplified sequence 1
MGC12488
NRTN neurturin
NXPH4 neurexophilin 4
OLFML3 olfactomedin-like 3
PACS1 phosphofurin acidic cluster sorting protein 1
PARD6A par-6 family cell polarity regulator alpha
PARM1 prostate androgen-regulated mucin-like protein 1
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLD2 phospholipase D2
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PLEKHO1 pleckstrin homology domain containing, family O member 1
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
PYCRL pyrroline-5-carboxylate reductase-like
RAB35 RAB35, member RAS oncogene family
RNF126P1 ring finger protein 126 pseudogene 1
SCGB2A2 secretoglobin, family 2A, member 2
SETD8 SET domain containing (lysine methyltransferase) 8
SETMAR SET domain and mariner transposase fusion gene
STARD3 StAR-related lipid transfer (START) domain containing 3
STON1 stonin 1
TENM1 teneurin transmembrane protein 1
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TINAGL1 tubulointerstitial nephritis antigen-like 1
TMEM156 transmembrane protein 156
TRIM58 tripartite motif containing 58
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TTC30A tetratricopeptide repeat domain 30A
TUBA3C tubulin, alpha 3c
UBIAD1 UbiA prenyltransferase domain containing 1
URGCP upregulator of cell proliferation
USP27X ubiquitin specific peptidase 27, X-linked
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZBTB39 zinc finger and BTB domain containing 39
ZNF205 zinc finger protein 205
ZNF230 zinc finger protein 230
ZNF34 zinc finger protein 34
ZNF510 zinc finger protein 510
ZNF528 zinc finger protein 528
ZNF671 zinc finger protein 671
ZNF768 zinc finger protein 768
ZNHIT2 zinc finger, HIT-type containing 2
ZW10 zw10 kinetochore protein