clomipramine-4487 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

195 genes differentially expressed following the clomipramine-4487 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2
AKR1C4 aldo-keto reductase family 1, member C4
ALDH6A1 aldehyde dehydrogenase 6 family, member A1
ALOX15B arachidonate 15-lipoxygenase, type B
ALOX5 arachidonate 5-lipoxygenase
ALPK1 alpha-kinase 1
APOC4 apolipoprotein C-IV
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
BIRC3 baculoviral IAP repeat containing 3
BTF3P11 basic transcription factor 3 pseudogene 11
C1ORF116 chromosome 1 open reading frame 116
C1QB complement component 1, q subcomponent, B chain
C20ORF195 chromosome 20 open reading frame 195
C7ORF69 chromosome 7 open reading frame 69
CCL5 chemokine (C-C motif) ligand 5
CD6 CD6 molecule
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7
CSHL1 chorionic somatomammotropin hormone-like 1
CXCL8 chemokine (C-X-C motif) ligand 8
CXORF21 chromosome X open reading frame 21
CYR61 cysteine-rich, angiogenic inducer, 61
DCN decorin
DDIT3 DNA-damage-inducible transcript 3
DENND3 DENN/MADD domain containing 3
EDNRA endothelin receptor type A
FASN fatty acid synthase
FBXO40 F-box protein 40
FGB fibrinogen beta chain
FGFR2 fibroblast growth factor receptor 2
FLJ11292
FLJ21369 uncharacterized protein FLJ21369
FYB FYN binding protein
GJA8 gap junction protein, alpha 8, 50kDa
GRM8 glutamate receptor, metabotropic 8
HDAC9 histone deacetylase 9
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
ICAM1 intercellular adhesion molecule 1
IFITM1 interferon induced transmembrane protein 1
IGHA1 immunoglobulin heavy constant alpha 1
IL1RN interleukin 1 receptor antagonist
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
KCNJ1 potassium channel, inwardly rectifying subfamily J, member 1
KLF13 Kruppel-like factor 13
KRT19P2 keratin 19 pseudogene 2
KRT34 keratin 34, type I
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
MMP13 matrix metallopeptidase 13
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MRAS muscle RAS oncogene homolog
MYT1 myelin transcription factor 1
NAG18 NAG18 mRNA
NPR1 natriuretic peptide receptor 1
NR4A2 nuclear receptor subfamily 4, group A, member 2
PCYT1B phosphate cytidylyltransferase 1, choline, beta
PDE12 phosphodiesterase 12
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PDE7B phosphodiesterase 7B
PKD2L2 polycystic kidney disease 2-like 2
PLIN2 perilipin 2
PTGER3 prostaglandin E receptor 3 (subtype EP3)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPRR protein tyrosine phosphatase, receptor type, R
PTX3 pentraxin 3, long
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RBPMS RNA binding protein with multiple splicing
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RNF126P1 ring finger protein 126 pseudogene 1
RPLP2 ribosomal protein, large, P2
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SFTPB surfactant protein B
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
SIGLEC8 sialic acid binding Ig-like lectin 8
SLC16A6 solute carrier family 16, member 6
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SNCG synuclein, gamma (breast cancer-specific protein 1)
SP100 SP100 nuclear antigen
SPAG8 sperm associated antigen 8
SPATA1 spermatogenesis associated 1
SPRR1A small proline-rich protein 1A
SSX1 synovial sarcoma, X breakpoint 1
ST3GAL6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6
TBX6 T-box 6
TCP11L1 t-complex 11, testis-specific-like 1
TGFB2 transforming growth factor, beta 2
TMEM246 transmembrane protein 246
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TRPC4 transient receptor potential cation channel, subfamily C, member 4
VNN1 vanin 1
ZNF440 zinc finger protein 440
ZXDB zinc finger, X-linked, duplicated B
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1

decreased expression

Symbol Name
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
ANAPC1 anaphase promoting complex subunit 1
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3
BANP BTG3 associated nuclear protein
BEX1 brain expressed, X-linked 1
C14ORF93 chromosome 14 open reading frame 93
C7ORF43 chromosome 7 open reading frame 43
CAMTA2 calmodulin binding transcription activator 2
CAND2 cullin-associated and neddylation-dissociated 2 (putative)
CBR3 carbonyl reductase 3
CCNO cyclin O
CCP110 centriolar coiled coil protein 110kDa
CEP295 centrosomal protein 295kDa
CFAP44 cilia and flagella associated protein 44
CLIC3 chloride intracellular channel 3
CPEB1 cytoplasmic polyadenylation element binding protein 1
CRY2 cryptochrome circadian clock 2
CSTF3 cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
DNAJB14 DnaJ (Hsp40) homolog, subfamily B, member 14
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24
E2F8 E2F transcription factor 8
EDIL3 EGF-like repeats and discoidin I-like domains 3
F2RL1 coagulation factor II (thrombin) receptor-like 1
FAM172A family with sequence similarity 172, member A
FBXL7 F-box and leucine-rich repeat protein 7
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FZD3 frizzled class receptor 3
GLDC glycine dehydrogenase (decarboxylating)
GSTCD glutathione S-transferase, C-terminal domain containing
GUSBP3 glucuronidase, beta pseudogene 3
HIRA histone cell cycle regulator
HIST1H1D histone cluster 1, H1d
HIST1H4C histone cluster 1, H4c
HLX H2.0-like homeobox
HMGB3 high mobility group box 3
HOXB13 homeobox B13
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IFI44L interferon-induced protein 44-like
IFI6 interferon, alpha-inducible protein 6
IL33 interleukin 33
IMPACT impact RWD domain protein
INCENP inner centromere protein antigens 135/155kDa
KIAA0753 KIAA0753
KIRREL kin of IRRE like (Drosophila)
LGR4 leucine-rich repeat containing G protein-coupled receptor 4
LOC730101 uncharacterized LOC730101
LPAR6 lysophosphatidic acid receptor 6
LRRC37A4P leucine rich repeat containing 37, member A4, pseudogene
MAGEA6 melanoma antigen family A6
MAST3 microtubule associated serine/threonine kinase 3
MED9 mediator complex subunit 9
NDP Norrie disease (pseudoglioma)
NDRG4 NDRG family member 4
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NMB neuromedin B
NMRK1 nicotinamide riboside kinase 1
NOD1 nucleotide-binding oligomerization domain containing 1
ORC1 origin recognition complex, subunit 1
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PALMD palmdelphin
PER3 period circadian clock 3
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
POLA2 polymerase (DNA directed), alpha 2, accessory subunit
PTGFR prostaglandin F receptor (FP)
QDPR quinoid dihydropteridine reductase
RABL6 RAB, member RAS oncogene family-like 6
RBL1 retinoblastoma-like 1
RNF121 ring finger protein 121
RPL23AP32 ribosomal protein L23a pseudogene 32
RRAGB Ras-related GTP binding B
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SECISBP2 SECIS binding protein 2
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1
SF3A3 splicing factor 3a, subunit 3, 60kDa
SH2D4A SH2 domain containing 4A
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC9A7 solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7
SP140L SP140 nuclear body protein-like
TAOK1 TAO kinase 1
TBCCD1 TBCC domain containing 1
TBXAS1 thromboxane A synthase 1 (platelet)
TENM4 teneurin transmembrane protein 4
TMCC2 transmembrane and coiled-coil domain family 2
TMEM242 transmembrane protein 242
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
TUBA1A tubulin, alpha 1a
WDR4 WD repeat domain 4
WDR76 WD repeat domain 76
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
ZKSCAN4 zinc finger with KRAB and SCAN domains 4
ZNF573 zinc finger protein 573
ZNF671 zinc finger protein 671
ZNF675 zinc finger protein 675