clonidine-3172 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

193 genes differentially expressed following the clonidine-3172 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A1CF APOBEC1 complementation factor
ACTA1 actin, alpha 1, skeletal muscle
AGPS alkylglycerone phosphate synthase
ALOXE3 arachidonate lipoxygenase 3
AP4E1 adaptor-related protein complex 4, epsilon 1 subunit
ARL3 ADP-ribosylation factor-like 3
ARNT aryl hydrocarbon receptor nuclear translocator
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ASB1 ankyrin repeat and SOCS box containing 1
B4GALT6 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6
BCL2L1 BCL2-like 1
BDKRB2 bradykinin receptor B2
BMP2 bone morphogenetic protein 2
CASP8 caspase 8, apoptosis-related cysteine peptidase
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCDC102B coiled-coil domain containing 102B
CCDC57 coiled-coil domain containing 57
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CELF2 CUGBP, Elav-like family member 2
CEP250 centrosomal protein 250kDa
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CPED1 cadherin-like and PC-esterase domain containing 1
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CYP4F8 cytochrome P450, family 4, subfamily F, polypeptide 8
DCBLD2 discoidin, CUB and LCCL domain containing 2
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
EBF2 early B-cell factor 2
ERC2-IT1 ERC2 intronic transcript 1
ETV1 ets variant 1
FBXO21 F-box protein 21
FGFR1 fibroblast growth factor receptor 1
FGFR2 fibroblast growth factor receptor 2
FLT1 fms-related tyrosine kinase 1
FSCN1 fascin actin-bundling protein 1
GNG13 guanine nucleotide binding protein (G protein), gamma 13
GPM6A glycoprotein M6A
GPR68 G protein-coupled receptor 68
GRIP2 glutamate receptor interacting protein 2
GSTA3 glutathione S-transferase alpha 3
HAAO 3-hydroxyanthranilate 3,4-dioxygenase
HEY2 hes-related family bHLH transcription factor with YRPW motif 2
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HOXA10 homeobox A10
IGFBP7 insulin-like growth factor binding protein 7
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
KDR kinase insert domain receptor
KIAA0040 KIAA0040
LCT lactase
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LPCAT4 lysophosphatidylcholine acyltransferase 4
MAST2 microtubule associated serine/threonine kinase 2
MCTP1 multiple C2 domains, transmembrane 1
MEG3 maternally expressed 3 (non-protein coding)
MGAM maltase-glucoamylase
MOB3B MOB kinase activator 3B
MRC2 mannose receptor, C type 2
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MYT1L myelin transcription factor 1-like
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NIPAL3 NIPA-like domain containing 3
NMBR neuromedin B receptor
NMT1 N-myristoyltransferase 1
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NPR1 natriuretic peptide receptor 1
NRAP nebulin-related anchoring protein
OBSL1 obscurin-like 1
OLIG2 oligodendrocyte lineage transcription factor 2
OR2B6 olfactory receptor, family 2, subfamily B, member 6
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
OSMR oncostatin M receptor
PAX5 paired box 5
PDE4DIP phosphodiesterase 4D interacting protein
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha
PVRL1 poliovirus receptor-related 1 (herpesvirus entry mediator C)
RAB6A RAB6A, member RAS oncogene family
SATB2 SATB homeobox 2
SERPINA2 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 2 (gene/pseudogene)
SLC25A42 solute carrier family 25, member 42
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
SOX30 SRY (sex determining region Y)-box 30
SPTA1 spectrin, alpha, erythrocytic 1
TDRKH tudor and KH domain containing
TEP1 telomerase-associated protein 1
THBD thrombomodulin
TRIM36 tripartite motif containing 36
TRPM2 transient receptor potential cation channel, subfamily M, member 2
TTLL5 tubulin tyrosine ligase-like family member 5
VAV2 vav 2 guanine nucleotide exchange factor
WDR4 WD repeat domain 4
WIPF1 WAS/WASL interacting protein family, member 1
WSB1 WD repeat and SOCS box containing 1
YIPF4 Yip1 domain family, member 4
ZIC3 Zic family member 3
ZNF358 zinc finger protein 358

decreased expression

Symbol Name
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ADGRG2 adhesion G protein-coupled receptor G2
ADRA2C adrenoceptor alpha 2C
ALG12 ALG12, alpha-1,6-mannosyltransferase
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
ASPHD1 aspartate beta-hydroxylase domain containing 1
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
CDKL3 cyclin-dependent kinase-like 3
CLCF1 cardiotrophin-like cytokine factor 1
CNGB3 cyclic nucleotide gated channel beta 3
CRY2 cryptochrome circadian clock 2
CRYBB2P1 crystallin, beta B2 pseudogene 1
CST6 cystatin E/M
DMTN dematin actin binding protein
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
EFNA3 ephrin-A3
EMID1 EMI domain containing 1
ERO1L ERO1-like (S. cerevisiae)
FGF4 fibroblast growth factor 4
FGL1 fibrinogen-like 1
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GMPR guanosine monophosphate reductase
GPATCH3 G patch domain containing 3
GPX1 glutathione peroxidase 1
GPX2 glutathione peroxidase 2
HIST1H1E histone cluster 1, H1e
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HMOX1 heme oxygenase 1
HOXC8 homeobox C8
IPO8 importin 8
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KDM8 lysine (K)-specific demethylase 8
KIAA0754 KIAA0754
KIAA1456 KIAA1456
KIF13B kinesin family member 13B
KRT83 keratin 83, type II
LATS1 large tumor suppressor kinase 1
LDHB lactate dehydrogenase B
LHFPL2 lipoma HMGIC fusion partner-like 2
LHX1 LIM homeobox 1
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
LOC729164 hCG1732469
LYZ lysozyme
MAP1S microtubule-associated protein 1S
MAST3 microtubule associated serine/threonine kinase 3
MEIS2 Meis homeobox 2
MFSD12 major facilitator superfamily domain containing 12
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MPO myeloperoxidase
MSI1 musashi RNA-binding protein 1
MUC3A mucin 3A, cell surface associated
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NNAT neuronatin
NRSN2 neurensin 2
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
OBFC1 oligonucleotide/oligosaccharide-binding fold containing 1
PCBP4 poly(rC) binding protein 4
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
PRSS22 protease, serine, 22
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
RAD54L2 RAD54-like 2 (S. cerevisiae)
RASL11B RAS-like, family 11, member B
RELN reelin
RNF123 ring finger protein 123
SCAMP5 secretory carrier membrane protein 5
SCGB2A2 secretoglobin, family 2A, member 2
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC44A1 solute carrier family 44 (choline transporter), member 1
SND1-IT1 SND1 intronic transcript 1
SRD5A3 steroid 5 alpha-reductase 3
SRGN serglycin
STAG3 stromal antigen 3
STK16 serine/threonine kinase 16
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
TESC tescalcin
TET3 tet methylcytosine dioxygenase 3
TIGD6 tigger transposable element derived 6
TMEM120B transmembrane protein 120B
TMEM180 transmembrane protein 180
TOM1 target of myb1 (chicken)
TUBA3C tubulin, alpha 3c
UPK3B uroplakin 3B
USP27X ubiquitin specific peptidase 27, X-linked
ZNF227 zinc finger protein 227
ZNF324 zinc finger protein 324
ZNF365 zinc finger protein 365
ZNF696 zinc finger protein 696