clonidine-6814 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the clonidine-6814 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM23 ADAM metallopeptidase domain 23
ADCK2 aarF domain containing kinase 2
ADGRA2 adhesion G protein-coupled receptor A2
ADGRD2 adhesion G protein-coupled receptor D2
ARTN artemin
ATN1 atrophin 1
BIN1 bridging integrator 1
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
BST2 bone marrow stromal cell antigen 2
C19ORF66 chromosome 19 open reading frame 66
C1ORF54 chromosome 1 open reading frame 54
C7ORF69 chromosome 7 open reading frame 69
CAPN5 calpain 5
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CLEC2D C-type lectin domain family 2, member D
CLIP2 CAP-GLY domain containing linker protein 2
CNN1 calponin 1, basic, smooth muscle
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
DKK3 dickkopf WNT signaling pathway inhibitor 3
DLGAP4 discs, large (Drosophila) homolog-associated protein 4
DMP1 dentin matrix acidic phosphoprotein 1
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DOK4 docking protein 4
ELAVL3 ELAV like neuron-specific RNA binding protein 3
EPHB2 EPH receptor B2
FAM50B family with sequence similarity 50, member B
GAD1 glutamate decarboxylase 1 (brain, 67kDa)
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GRM1 glutamate receptor, metabotropic 1
GSAP gamma-secretase activating protein
HAAO 3-hydroxyanthranilate 3,4-dioxygenase
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HIPK2 homeodomain interacting protein kinase 2
IFI27 interferon, alpha-inducible protein 27
IFI6 interferon, alpha-inducible protein 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFITM1 interferon induced transmembrane protein 1
IGHM immunoglobulin heavy constant mu
IRF9 interferon regulatory factor 9
ISG15 ISG15 ubiquitin-like modifier
ISG20 interferon stimulated exonuclease gene 20kDa
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITM2C integral membrane protein 2C
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KHK ketohexokinase (fructokinase)
LAPTM5 lysosomal protein transmembrane 5
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LMO2 LIM domain only 2 (rhombotin-like 1)
LTBP4 latent transforming growth factor beta binding protein 4
MAPK7 mitogen-activated protein kinase 7
MBNL2 muscleblind-like splicing regulator 2
MMP16 matrix metallopeptidase 16 (membrane-inserted)
MNDA myeloid cell nuclear differentiation antigen
MYH14 myosin, heavy chain 14, non-muscle
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NOP16 NOP16 nucleolar protein
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
PCDH1 protocadherin 1
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PLAT plasminogen activator, tissue
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PTPRJ protein tyrosine phosphatase, receptor type, J
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
RAD52 RAD52 homolog (S. cerevisiae)
RARA retinoic acid receptor, alpha
RB1 retinoblastoma 1
RBP4 retinol binding protein 4, plasma
RCHY1 ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase
RIMS3 regulating synaptic membrane exocytosis 3
RND1 Rho family GTPase 1
RPH3A rabphilin 3A
RPS3A ribosomal protein S3A
RRN3P1 RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SIX3 SIX homeobox 3
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SOX9 SRY (sex determining region Y)-box 9
SP110 SP110 nuclear body protein
SRC SRC proto-oncogene, non-receptor tyrosine kinase
TAL1 T-cell acute lymphocytic leukemia 1
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TBR1 T-box, brain, 1
TCP11L1 t-complex 11, testis-specific-like 1
TLE2 transducin-like enhancer of split 2
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TONSL tonsoku-like, DNA repair protein
TRD T cell receptor delta locus
TRIM21 tripartite motif containing 21
TRIM31 tripartite motif containing 31
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
USP22 ubiquitin specific peptidase 22
VIPR2 vasoactive intestinal peptide receptor 2
WDR33 WD repeat domain 33
ZBTB7A zinc finger and BTB domain containing 7A
ZNF134 zinc finger protein 134
ZNF440 zinc finger protein 440

decreased expression

Symbol Name
ACP2 acid phosphatase 2, lysosomal
ADAM15 ADAM metallopeptidase domain 15
ADAP2 ArfGAP with dual PH domains 2
ADGRG2 adhesion G protein-coupled receptor G2
AKAP12 A kinase (PRKA) anchor protein 12
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma
ASPHD1 aspartate beta-hydroxylase domain containing 1
AUTS2 autism susceptibility candidate 2
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BAHD1 bromo adjacent homology domain containing 1
BATF basic leucine zipper transcription factor, ATF-like
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
C16ORF45 chromosome 16 open reading frame 45
C17ORF80 chromosome 17 open reading frame 80
C19ORF73 chromosome 19 open reading frame 73
C1ORF105 chromosome 1 open reading frame 105
CAMK1 calcium/calmodulin-dependent protein kinase I
CAMK1D calcium/calmodulin-dependent protein kinase ID
CCDC186 coiled-coil domain containing 186
CD82 CD82 molecule
CDKL3 cyclin-dependent kinase-like 3
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CIR1 corepressor interacting with RBPJ, 1
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
CSF1R colony stimulating factor 1 receptor
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EFNA3 ephrin-A3
EIF5A2 eukaryotic translation initiation factor 5A2
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM46C family with sequence similarity 46, member C
FILIP1L filamin A interacting protein 1-like
FMOD fibromodulin
GCHFR GTP cyclohydrolase I feedback regulator
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GPX2 glutathione peroxidase 2
GSTCD glutathione S-transferase, C-terminal domain containing
GSTTP1 glutathione S-transferase theta pseudogene 1
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HIST1H1D histone cluster 1, H1d
HIST1H2AJ histone cluster 1, H2aj
HOXC8 homeobox C8
HYI hydroxypyruvate isomerase (putative)
IL20RA interleukin 20 receptor, alpha
KBTBD11 kelch repeat and BTB (POZ) domain containing 11
KRT15 keratin 15, type I
LMNB1 lamin B1
LRRC61 leucine rich repeat containing 61
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MED15 mediator complex subunit 15
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MTCP1 mature T-cell proliferation 1
MUL1 mitochondrial E3 ubiquitin protein ligase 1
NCALD neurocalcin delta
NEK11 NIMA-related kinase 11
NOL10 nucleolar protein 10
NT5DC3 5'-nucleotidase domain containing 3
NXPE3 neurexophilin and PC-esterase domain family, member 3
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
OVGP1 oviductal glycoprotein 1, 120kDa
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PCDHB3 protocadherin beta 3
PCSK7 proprotein convertase subtilisin/kexin type 7
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PHC1 polyhomeotic homolog 1 (Drosophila)
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLD3 phospholipase D family, member 3
PLEKHO2 pleckstrin homology domain containing, family O member 2
PODNL1 podocan-like 1
POLH polymerase (DNA directed), eta
POMT2 protein-O-mannosyltransferase 2
PP14571 uncharacterized LOC100130449
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PRPH peripherin
PRR4 proline rich 4 (lacrimal)
PSG4 pregnancy specific beta-1-glycoprotein 4
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
SCRN3 secernin 3
SLC12A9 solute carrier family 12, member 9
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
SPATA2L spermatogenesis associated 2-like
ST5 suppression of tumorigenicity 5
STK16 serine/threonine kinase 16
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TESK1 testis-specific kinase 1
THNSL2 threonine synthase-like 2 (S. cerevisiae)
TMEM212 transmembrane protein 212
TRMT13 tRNA methyltransferase 13 homolog (S. cerevisiae)
TTBK2 tau tubulin kinase 2
TUBA3C tubulin, alpha 3c
UPP1 uridine phosphorylase 1
WFDC2 WAP four-disulfide core domain 2
ZNF286A zinc finger protein 286A
ZNF34 zinc finger protein 34
ZNF37BP zinc finger protein 37B, pseudogene
ZNF552 zinc finger protein 552