clopamide-3220 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the clopamide-3220 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ACE angiotensin I converting enzyme
ACRV1 acrosomal vesicle protein 1
AFAP1 actin filament associated protein 1
AKAP7 A kinase (PRKA) anchor protein 7
APOM apolipoprotein M
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10
CASP4 caspase 4, apoptosis-related cysteine peptidase
CDK14 cyclin-dependent kinase 14
CLIP2 CAP-GLY domain containing linker protein 2
CLTA clathrin, light chain A
COPZ2 coatomer protein complex, subunit zeta 2
CPQ carboxypeptidase Q
CXCR4 chemokine (C-X-C motif) receptor 4
CYHR1 cysteine/histidine-rich 1
DBP D site of albumin promoter (albumin D-box) binding protein
DRD2 dopamine receptor D2
DVL3 dishevelled segment polarity protein 3
EFNA3 ephrin-A3
EFNB3 ephrin-B3
EFR3B EFR3 homolog B (S. cerevisiae)
ELP6 elongator acetyltransferase complex subunit 6
EMC3 ER membrane protein complex subunit 3
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
ESRRA estrogen-related receptor alpha
FYB FYN binding protein
GEMIN7 gem (nuclear organelle) associated protein 7
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GREB1 growth regulation by estrogen in breast cancer 1
GRIP2 glutamate receptor interacting protein 2
HCRP1 hepatocellular carcinoma-related HCRP1
HOXA10 homeobox A10
HOXA4 homeobox A4
HSPB3 heat shock 27kDa protein 3
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
IL1RN interleukin 1 receptor antagonist
IL20RA interleukin 20 receptor, alpha
INPP5B inositol polyphosphate-5-phosphatase, 75kDa
INTS1 integrator complex subunit 1
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
LAMA4 laminin, alpha 4
LOXL3 lysyl oxidase-like 3
LTB4R leukotriene B4 receptor
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
METTL7A methyltransferase like 7A
NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2
NDUFAF5 NADH dehydrogenase (ubiquinone) complex I, assembly factor 5
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NF1 neurofibromin 1
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NOL10 nucleolar protein 10
NPTX1 neuronal pentraxin I
NR4A2 nuclear receptor subfamily 4, group A, member 2
NTN3 netrin 3
OCM2 oncomodulin 2
PAPOLA poly(A) polymerase alpha
PAX2 paired box 2
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PDE5A phosphodiesterase 5A, cGMP-specific
PLCD1 phospholipase C, delta 1
POU2F2 POU class 2 homeobox 2
PPP5C protein phosphatase 5, catalytic subunit
PRB4 proline-rich protein BstNI subfamily 4
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
RAB30 RAB30, member RAS oncogene family
RARA retinoic acid receptor, alpha
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
RSU1 Ras suppressor protein 1
RUNX1 runt-related transcription factor 1
SBF1 SET binding factor 1
SCUBE3 signal peptide, CUB domain, EGF-like 3
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SEMA4F sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F
SIRT5 sirtuin 5
SLAMF7 SLAM family member 7
SMAD3 SMAD family member 3
SMAD4 SMAD family member 4
SPRR1A small proline-rich protein 1A
SPTBN1 spectrin, beta, non-erythrocytic 1
TAGLN3 transgelin 3
TAPBP TAP binding protein (tapasin)
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TFF2 trefoil factor 2
THAP3 THAP domain containing, apoptosis associated protein 3
TLK1 tousled-like kinase 1
TMEM121 transmembrane protein 121
TMEM144 transmembrane protein 144
TMEM242 transmembrane protein 242
TMEM53 transmembrane protein 53
TUBA3C tubulin, alpha 3c
VWA5A von Willebrand factor A domain containing 5A
ZMIZ2 zinc finger, MIZ-type containing 2
ZNF226 zinc finger protein 226
ZNF280B zinc finger protein 280B
ZNF747 zinc finger protein 747

decreased expression

Symbol Name
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2
AIPL1 aryl hydrocarbon receptor interacting protein-like 1
C11ORF16 chromosome 11 open reading frame 16
C19ORF73 chromosome 19 open reading frame 73
C21ORF91 chromosome 21 open reading frame 91
C2ORF54 chromosome 2 open reading frame 54
CA5BP1 carbonic anhydrase VB pseudogene 1
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CAPN5 calpain 5
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CES1 carboxylesterase 1
CIDEB cell death-inducing DFFA-like effector b
CLCF1 cardiotrophin-like cytokine factor 1
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
CNR2 cannabinoid receptor 2 (macrophage)
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CTNNBIP1 catenin, beta interacting protein 1
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
DAGLA diacylglycerol lipase, alpha
DIXDC1 DIX domain containing 1
DPYS dihydropyrimidinase
DUSP13 dual specificity phosphatase 13
DYSF dysferlin
ERN2 endoplasmic reticulum to nucleus signaling 2
ETAA1 Ewing tumor-associated antigen 1
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
FKBP10 FK506 binding protein 10, 65 kDa
FLJ11710 uncharacterized protein FLJ11710
FRS2 fibroblast growth factor receptor substrate 2
FURIN furin (paired basic amino acid cleaving enzyme)
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GALK1 galactokinase 1
GLTSCR1 glioma tumor suppressor candidate region gene 1
GPR1 G protein-coupled receptor 1
GPR87 G protein-coupled receptor 87
HDAC11 histone deacetylase 11
HIST1H2AL histone cluster 1, H2al
HIST1H2BI histone cluster 1, H2bi
HIST1H4F histone cluster 1, H4f
HOXC5 homeobox C5
HOXC8 homeobox C8
HYI hydroxypyruvate isomerase (putative)
IDI2-AS1 IDI2 antisense RNA 1
IL15RA interleukin 15 receptor, alpha
INCENP inner centromere protein antigens 135/155kDa
IRF6 interferon regulatory factor 6
KCNMB4 potassium channel subfamily M regulatory beta subunit 4
KCNQ3 potassium channel, voltage gated KQT-like subfamily Q, member 3
KREMEN2 kringle containing transmembrane protein 2
LAX1 lymphocyte transmembrane adaptor 1
LDHB lactate dehydrogenase B
LIG4 ligase IV, DNA, ATP-dependent
LOC390998 ribosomal protein L10 pseudogene
LRRC23 leucine rich repeat containing 23
LRRC37A2 leucine rich repeat containing 37, member A2
LYZ lysozyme
LZTS3 leucine zipper, putative tumor suppressor family member 3
MBNL3 muscleblind-like splicing regulator 3
MED15 mediator complex subunit 15
MUC3A mucin 3A, cell surface associated
MVD mevalonate (diphospho) decarboxylase
NDE1 nudE neurodevelopment protein 1
NDRG4 NDRG family member 4
NIPAL2 NIPA-like domain containing 2
NR1H3 nuclear receptor subfamily 1, group H, member 3
PACS1 phosphofurin acidic cluster sorting protein 1
PALM paralemmin
PCDHB3 protocadherin beta 3
PCDHGB5 protocadherin gamma subfamily B, 5
PLEKHO2 pleckstrin homology domain containing, family O member 2
POLL polymerase (DNA directed), lambda
POMT2 protein-O-mannosyltransferase 2
PRPH peripherin
PTPN14 protein tyrosine phosphatase, non-receptor type 14
RAD54L2 RAD54-like 2 (S. cerevisiae)
RASA2 RAS p21 protein activator 2
REM1 RAS (RAD and GEM)-like GTP-binding 1
RNF122 ring finger protein 122
SAMD9 sterile alpha motif domain containing 9
SAYSD1 SAYSVFN motif domain containing 1
SCGB2A2 secretoglobin, family 2A, member 2
SECTM1 secreted and transmembrane 1
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SRPX sushi-repeat containing protein, X-linked
TFDP3 transcription factor Dp family, member 3
TRIM21 tripartite motif containing 21
UNC93B1 unc-93 homolog B1 (C. elegans)
USP27X ubiquitin specific peptidase 27, X-linked
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
XYLT2 xylosyltransferase II
ZIC3 Zic family member 3
ZNF134 zinc finger protein 134
ZNF480 zinc finger protein 480
ZNF696 zinc finger protein 696
ZSCAN26 zinc finger and SCAN domain containing 26