clopamide-5402 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the clopamide-5402 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A2M alpha-2-macroglobulin
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ACTA1 actin, alpha 1, skeletal muscle
AFAP1 actin filament associated protein 1
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
AKR1C1 aldo-keto reductase family 1, member C1
ALDOB aldolase B, fructose-bisphosphate
ALOX15 arachidonate 15-lipoxygenase
ARNT aryl hydrocarbon receptor nuclear translocator
ARTN artemin
ASIC4 acid sensing (proton gated) ion channel family member 4
BHLHE40 basic helix-loop-helix family, member e40
C22ORF46 chromosome 22 open reading frame 46
C3 complement component 3
CAMK2G calcium/calmodulin-dependent protein kinase II gamma
CEP164 centrosomal protein 164kDa
CFAP70 cilia and flagella associated protein 70
CFLAR CASP8 and FADD-like apoptosis regulator
CLCN7 chloride channel, voltage-sensitive 7
CLDN17 claudin 17
CLPS colipase, pancreatic
COL11A2 collagen, type XI, alpha 2
CPEB3 cytoplasmic polyadenylation element binding protein 3
CTAGE1 cutaneous T-cell lymphoma-associated antigen 1
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP2W1 cytochrome P450, family 2, subfamily W, polypeptide 1
CYR61 cysteine-rich, angiogenic inducer, 61
DAPK2 death-associated protein kinase 2
DESI2 desumoylating isopeptidase 2
DMTN dematin actin binding protein
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM135A family with sequence similarity 135, member A
FANCA Fanconi anemia, complementation group A
FBXO11 F-box protein 11
FBXO41 F-box protein 41
FGD1 FYVE, RhoGEF and PH domain containing 1
FGF1 fibroblast growth factor 1 (acidic)
FGF3 fibroblast growth factor 3
GAS7 growth arrest-specific 7
GJA4 gap junction protein, alpha 4, 37kDa
GLRA1 glycine receptor, alpha 1
GM2A GM2 ganglioside activator
GPR137 G protein-coupled receptor 137
GRM3 glutamate receptor, metabotropic 3
HFE hemochromatosis
HGD homogentisate 1,2-dioxygenase
HIST1H4D histone cluster 1, H4d
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
IFNW1 interferon, omega 1
INHBA inhibin, beta A
IRF4 interferon regulatory factor 4
IRF5 interferon regulatory factor 5
ISG20L2 interferon stimulated exonuclease gene 20kDa-like 2
IVL involucrin
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
MEF2D myocyte enhancer factor 2D
MLXIP MLX interacting protein
MMP3 matrix metallopeptidase 3
MST1 macrophage stimulating 1
MYL4 myosin, light chain 4, alkali; atrial, embryonic
N4BP1 NEDD4 binding protein 1
NGDN neuroguidin, EIF4E binding protein
NIPSNAP3B nipsnap homolog 3B (C. elegans)
NKX2-5 NK2 homeobox 5
NOV nephroblastoma overexpressed
NR4A1 nuclear receptor subfamily 4, group A, member 1
NUP188 nucleoporin 188kDa
PAIP2B poly(A) binding protein interacting protein 2B
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PCSK6 proprotein convertase subtilisin/kexin type 6
PDE3B phosphodiesterase 3B, cGMP-inhibited
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
PML promyelocytic leukemia
POLL polymerase (DNA directed), lambda
PRMT2IP PRMT2 interacting protein
PTCH2 patched 2
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
PVR poliovirus receptor
RIMS3 regulating synaptic membrane exocytosis 3
SIK3 SIK family kinase 3
SIPA1 signal-induced proliferation-associated 1
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9
SNRK SNF related kinase
SOS2 son of sevenless homolog 2 (Drosophila)
SOX9 SRY (sex determining region Y)-box 9
SP1 Sp1 transcription factor
TBC1D22A TBC1 domain family, member 22A
TGFBR1 transforming growth factor, beta receptor 1
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
WAPAL wings apart-like homolog (Drosophila)
ZMYND11 zinc finger, MYND-type containing 11
ZNF287 zinc finger protein 287
ZNF473 zinc finger protein 473
ZNF76 zinc finger protein 76

decreased expression

Symbol Name
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
APLP1 amyloid beta (A4) precursor-like protein 1
APOD apolipoprotein D
ARMC4 armadillo repeat containing 4
ARMC6 armadillo repeat containing 6
BAG4 BCL2-associated athanogene 4
BBC3 BCL2 binding component 3
C11ORF80 chromosome 11 open reading frame 80
C17ORF70 chromosome 17 open reading frame 70
C1ORF159 chromosome 1 open reading frame 159
CAPN5 calpain 5
CD79B CD79b molecule, immunoglobulin-associated beta
CD8A CD8a molecule
CES3 carboxylesterase 3
CIC capicua transcriptional repressor
CLGN calmegin
CLSTN2 calsyntenin 2
CORT cortistatin
CPPED1 calcineurin-like phosphoesterase domain containing 1
CPTP ceramide-1-phosphate transfer protein
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CRY2 cryptochrome circadian clock 2
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DIXDC1 DIX domain containing 1
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
EHMT1 euchromatic histone-lysine N-methyltransferase 1
EPHX2 epoxide hydrolase 2, cytoplasmic
ETAA1 Ewing tumor-associated antigen 1
FAM155B family with sequence similarity 155, member B
FAM46C family with sequence similarity 46, member C
GLS2 glutaminase 2 (liver, mitochondrial)
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HDAC5 histone deacetylase 5
HLA-DMA major histocompatibility complex, class II, DM alpha
IFI27 interferon, alpha-inducible protein 27
IFI6 interferon, alpha-inducible protein 6
INPP5J inositol polyphosphate-5-phosphatase J
IRX4 iroquois homeobox 4
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
KLK5 kallikrein-related peptidase 5
LIN7A lin-7 homolog A (C. elegans)
LRP2 low density lipoprotein receptor-related protein 2
LRP3 low density lipoprotein receptor-related protein 3
LYPD1 LY6/PLAUR domain containing 1
MAP1S microtubule-associated protein 1S
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MAPKBP1 mitogen-activated protein kinase binding protein 1
MFAP2 microfibrillar-associated protein 2
MICALL2 MICAL-like 2
MTERF4 mitochondrial transcription termination factor 4
MUL1 mitochondrial E3 ubiquitin protein ligase 1
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NPFFR1 neuropeptide FF receptor 1
NPTX1 neuronal pentraxin I
NRGN neurogranin (protein kinase C substrate, RC3)
OLFML2A olfactomedin-like 2A
ONECUT2 one cut homeobox 2
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PACS1 phosphofurin acidic cluster sorting protein 1
PCSK7 proprotein convertase subtilisin/kexin type 7
PDE12 phosphodiesterase 12
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PGBD5 piggyBac transposable element derived 5
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
RAB11FIP5 RAB11 family interacting protein 5 (class I)
RAB3D RAB3D, member RAS oncogene family
RNF126P1 ring finger protein 126 pseudogene 1
RPGR retinitis pigmentosa GTPase regulator
RPL13P5 ribosomal protein L13 pseudogene 5
S100A9 S100 calcium binding protein A9
SAYSD1 SAYSVFN motif domain containing 1
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SETD1A SET domain containing 1A
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SP140L SP140 nuclear body protein-like
SPINK5 serine peptidase inhibitor, Kazal type 5
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STARD13 StAR-related lipid transfer (START) domain containing 13
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TCTN1 tectonic family member 1
TEP1 telomerase-associated protein 1
TESC tescalcin
TET3 tet methylcytosine dioxygenase 3
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TMEM120B transmembrane protein 120B
TMEM212 transmembrane protein 212
TRIM36 tripartite motif containing 36
TTLL1 tubulin tyrosine ligase-like family member 1
USP27X ubiquitin specific peptidase 27, X-linked
VGF VGF nerve growth factor inducible
WFDC2 WAP four-disulfide core domain 2
ZNF205 zinc finger protein 205
ZNF551 zinc finger protein 551