clopamide-6301 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the clopamide-6301 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABI2 abl-interactor 2
ADD2 adducin 2 (beta)
ANGEL2 angel homolog 2 (Drosophila)
AP1G2 adaptor-related protein complex 1, gamma 2 subunit
AP1M2 adaptor-related protein complex 1, mu 2 subunit
APOC4 apolipoprotein C-IV
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ATAT1 alpha tubulin acetyltransferase 1
ATXN2L ataxin 2-like
C19ORF40 chromosome 19 open reading frame 40
C1ORF95 chromosome 1 open reading frame 95
C1QTNF3 C1q and tumor necrosis factor related protein 3
CA5B carbonic anhydrase VB, mitochondrial
CCDC57 coiled-coil domain containing 57
CCDC88A coiled-coil domain containing 88A
CCL27 chemokine (C-C motif) ligand 27
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CENPT centromere protein T
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal)
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
COL16A1 collagen, type XVI, alpha 1
COL3A1 collagen, type III, alpha 1
COQ7 coenzyme Q7 homolog, ubiquinone (yeast)
CREB5 cAMP responsive element binding protein 5
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
CTNS cystinosin, lysosomal cystine transporter
DGKE diacylglycerol kinase, epsilon 64kDa
DMTN dematin actin binding protein
EFNA3 ephrin-A3
ELAVL3 ELAV like neuron-specific RNA binding protein 3
ETV6 ets variant 6
FAIM2 Fas apoptotic inhibitory molecule 2
FBXL7 F-box and leucine-rich repeat protein 7
FCMR Fc fragment of IgM receptor
FCN1 ficolin (collagen/fibrinogen domain containing) 1
GARNL3 GTPase activating Rap/RanGAP domain-like 3
GOLGA2 golgin A2
HOXB2 homeobox B2
IDS iduronate 2-sulfatase
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
IL22 interleukin 22
KIAA1107 KIAA1107
KRIT1 KRIT1, ankyrin repeat containing
KRT19P2 keratin 19 pseudogene 2
LMBR1L limb development membrane protein 1-like
LPCAT3 lysophosphatidylcholine acyltransferase 3
LTC4S leukotriene C4 synthase
MAP3K13 mitogen-activated protein kinase kinase kinase 13
MVK mevalonate kinase
MX1 MX dynamin-like GTPase 1
MYH14 myosin, heavy chain 14, non-muscle
MYL10 myosin, light chain 10, regulatory
N4BP2L1 NEDD4 binding protein 2-like 1
PARP3 poly (ADP-ribose) polymerase family, member 3
PDE4DIP phosphodiesterase 4D interacting protein
PEX11A peroxisomal biogenesis factor 11 alpha
PLXNA2 plexin A2
PNMA2 paraneoplastic Ma antigen 2
PRDM2 PR domain containing 2, with ZNF domain
PTCH1 patched 1
PTGDR2 prostaglandin D2 receptor 2
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2
PVR poliovirus receptor
RAB11B RAB11B, member RAS oncogene family
RAB3A RAB3A, member RAS oncogene family
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RBM19 RNA binding motif protein 19
RGS12 regulator of G-protein signaling 12
RTN2 reticulon 2
SCN11A sodium channel, voltage gated, type XI alpha subunit
SHMT1 serine hydroxymethyltransferase 1 (soluble)
SIX3 SIX homeobox 3
SKIL SKI-like proto-oncogene
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
SMPX small muscle protein, X-linked
STX2 syntaxin 2
TBCD tubulin folding cofactor D
TECPR2 tectonin beta-propeller repeat containing 2
TEP1 telomerase-associated protein 1
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TGFB1 transforming growth factor, beta 1
TIMELESS timeless circadian clock
TLDC1 TBC/LysM-associated domain containing 1
TMEM53 transmembrane protein 53
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TOX thymocyte selection-associated high mobility group box
TRAC T cell receptor alpha constant
TRIM14 tripartite motif containing 14
TRIM62 tripartite motif containing 62
UBTD1 ubiquitin domain containing 1
UNC93B1 unc-93 homolog B1 (C. elegans)
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast)
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae)
WAPAL wings apart-like homolog (Drosophila)
ZNF292 zinc finger protein 292

decreased expression

Symbol Name
ADGRA3 adhesion G protein-coupled receptor A3
AGBL5 ATP/GTP binding protein-like 5
ARHGAP12 Rho GTPase activating protein 12
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ARL15 ADP-ribosylation factor-like 15
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
BAG4 BCL2-associated athanogene 4
BAMBI BMP and activin membrane-bound inhibitor
BATF3 basic leucine zipper transcription factor, ATF-like 3
BPGM 2,3-bisphosphoglycerate mutase
BSPRY B-box and SPRY domain containing
C11ORF80 chromosome 11 open reading frame 80
C1RL complement component 1, r subcomponent-like
CAMK1 calcium/calmodulin-dependent protein kinase I
CDC37L1 cell division cycle 37-like 1
CHCHD3 coiled-coil-helix-coiled-coil-helix domain containing 3
CHKB choline kinase beta
CHPF chondroitin polymerizing factor
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
CIDEC cell death-inducing DFFA-like effector c
COG7 component of oligomeric golgi complex 7
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DCAF17 DDB1 and CUL4 associated factor 17
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57
EDEM2 ER degradation enhancer, mannosidase alpha-like 2
EN2 engrailed homeobox 2
ERCC2 excision repair cross-complementation group 2
EXOC2 exocyst complex component 2
F3 coagulation factor III (thromboplastin, tissue factor)
FANCC Fanconi anemia, complementation group C
FAT4 FAT atypical cadherin 4
FGGY FGGY carbohydrate kinase domain containing
FOXA1 forkhead box A1
GAL3ST4 galactose-3-O-sulfotransferase 4
GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1
GCHFR GTP cyclohydrolase I feedback regulator
GJC1 gap junction protein, gamma 1, 45kDa
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GSTT1 glutathione S-transferase theta 1
H2AFY2 H2A histone family, member Y2
HIST1H2AJ histone cluster 1, H2aj
IFT54 intraflagellar transport 54
IRF9 interferon regulatory factor 9
KIAA0513 KIAA0513
LONRF3 LON peptidase N-terminal domain and ring finger 3
LPAR6 lysophosphatidic acid receptor 6
MAGEF1 melanoma antigen family F1
MEIS1 Meis homeobox 1
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
MOXD1 monooxygenase, DBH-like 1
NDE1 nudE neurodevelopment protein 1
NDUFS7 NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase)
NR3C2 nuclear receptor subfamily 3, group C, member 2
ONECUT2 one cut homeobox 2
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PDE12 phosphodiesterase 12
PER3 period circadian clock 3
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PILRB paired immunoglobin-like type 2 receptor beta
PLCD1 phospholipase C, delta 1
PLEKHO2 pleckstrin homology domain containing, family O member 2
POR P450 (cytochrome) oxidoreductase
PRMT7 protein arginine methyltransferase 7
PSKH1 protein serine kinase H1
PTCD2 pentatricopeptide repeat domain 2
RANBP17 RAN binding protein 17
RASA2 RAS p21 protein activator 2
RNF2 ring finger protein 2
SCAMP4 secretory carrier membrane protein 4
SH2D4A SH2 domain containing 4A
SH3TC2 SH3 domain and tetratricopeptide repeats 2
SIX1 SIX homeobox 1
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SPATA2L spermatogenesis associated 2-like
SPEG SPEG complex locus
SREBF1 sterol regulatory element binding transcription factor 1
SREK1IP1 SREK1-interacting protein 1
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STBD1 starch binding domain 1
STEAP3 STEAP family member 3, metalloreductase
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
TAGLN3 transgelin 3
TEX40 testis expressed 40
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TLN1 talin 1
TPST2 tyrosylprotein sulfotransferase 2
USB1 U6 snRNA biogenesis 1
USP6NL USP6 N-terminal like
VASP vasodilator-stimulated phosphoprotein
XAB2 XPA binding protein 2
ZNF205 zinc finger protein 205
ZNF253 zinc finger protein 253
ZNF304 zinc finger protein 304
ZNF442 zinc finger protein 442
ZNF675 zinc finger protein 675
ZNF862 zinc finger protein 862