cloperastine-2549 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the cloperastine-2549 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11
ADAM17 ADAM metallopeptidase domain 17
AHCYL2 adenosylhomocysteinase-like 2
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
ARHGAP1 Rho GTPase activating protein 1
ATP10B ATPase, class V, type 10B
BCL3 B-cell CLL/lymphoma 3
BTG2 BTG family, member 2
C20ORF195 chromosome 20 open reading frame 195
CASP10 caspase 10, apoptosis-related cysteine peptidase
CD6 CD6 molecule
CDC14B cell division cycle 14B
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CLIP4 CAP-GLY domain containing linker protein family, member 4
COL10A1 collagen, type X, alpha 1
CREBZF CREB/ATF bZIP transcription factor
CXCR6 chemokine (C-X-C motif) receptor 6
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
CYR61 cysteine-rich, angiogenic inducer, 61
DCAF13 DDB1 and CUL4 associated factor 13
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
EGFL7 EGF-like-domain, multiple 7
EMILIN2 elastin microfibril interfacer 2
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
FAM212B family with sequence similarity 212, member B
FCAR Fc fragment of IgA receptor
FGFR1 fibroblast growth factor receptor 1
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GNAT1 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1
GPC1 glypican 1
GRHL2 grainyhead-like 2 (Drosophila)
GSPT1 G1 to S phase transition 1
GSTA3 glutathione S-transferase alpha 3
GULP1 GULP, engulfment adaptor PTB domain containing 1
GYG2 glycogenin 2
HES1 hes family bHLH transcription factor 1
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
ICAM1 intercellular adhesion molecule 1
IQCA1 IQ motif containing with AAA domain 1
KHSRP KH-type splicing regulatory protein
KNG1 kininogen 1
LAD1 ladinin 1
LINC01587 long intergenic non-protein coding RNA 1587
LOC100287387 uncharacterized LOC100287387
MAP2K5 mitogen-activated protein kinase kinase 5
MAPK8 mitogen-activated protein kinase 8
MEFV Mediterranean fever
MMP13 matrix metallopeptidase 13
MTRF1L mitochondrial translational release factor 1-like
MYH14 myosin, heavy chain 14, non-muscle
MYL10 myosin, light chain 10, regulatory
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NOP14-AS1 NOP14 antisense RNA 1
NRCAM neuronal cell adhesion molecule
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PDE12 phosphodiesterase 12
PKD2L2 polycystic kidney disease 2-like 2
PMP2 peripheral myelin protein 2
POLDIP3 polymerase (DNA-directed), delta interacting protein 3
PPP1R2P9 protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 9
PRB1 proline-rich protein BstNI subfamily 1
PROL1 proline rich, lacrimal 1
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5
RBM34 RNA binding motif protein 34
REST RE1-silencing transcription factor
RIF1 replication timing regulatory factor 1
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila)
RTN2 reticulon 2
SCARB2 scavenger receptor class B, member 2
SERHL2 serine hydrolase-like 2
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
SLC35F6 solute carrier family 35, member F6
SMAD5 SMAD family member 5
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SNW1 SNW domain containing 1
SPAG11B sperm associated antigen 11B
SPRR2B small proline-rich protein 2B
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
SPTB spectrin, beta, erythrocytic
TBC1D30 TBC1 domain family, member 30
TBCD tubulin folding cofactor D
TLN2 talin 2
TMCC2 transmembrane and coiled-coil domain family 2
TMEM63A transmembrane protein 63A
TP53I3 tumor protein p53 inducible protein 3
TRBC1 T cell receptor beta constant 1
TRO trophinin
TTC30A tetratricopeptide repeat domain 30A
UPK3B uroplakin 3B
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
YY2 YY2 transcription factor
ZBTB20 zinc finger and BTB domain containing 20
ZFHX3 zinc finger homeobox 3
ZNF177 zinc finger protein 177
ZNF280B zinc finger protein 280B
ZNF750 zinc finger protein 750

decreased expression

Symbol Name
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ACYP1 acylphosphatase 1, erythrocyte (common) type
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
ANKFY1 ankyrin repeat and FYVE domain containing 1
ANKRD36 ankyrin repeat domain 36
ANXA3 annexin A3
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
ARMC6 armadillo repeat containing 6
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
BMP15 bone morphogenetic protein 15
C5ORF45 chromosome 5 open reading frame 45
C7ORF43 chromosome 7 open reading frame 43
CAPN15 calpain 15
CCNL2 cyclin L2
CD69 CD69 molecule
CDK20 cyclin-dependent kinase 20
CDR2L cerebellar degeneration-related protein 2-like
CENPT centromere protein T
CGREF1 cell growth regulator with EF-hand domain 1
CHMP6 charged multivesicular body protein 6
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal)
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CRYBB2P1 crystallin, beta B2 pseudogene 1
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
CYSLTR1 cysteinyl leukotriene receptor 1
DBR1 debranching RNA lariats 1
DSE dermatan sulfate epimerase
EXD3 exonuclease 3'-5' domain containing 3
FAM204A family with sequence similarity 204, member A
FBXW12 F-box and WD repeat domain containing 12
FEM1C fem-1 homolog c (C. elegans)
FJX1 four jointed box 1 (Drosophila)
GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4
HIST1H1T histone cluster 1, H1t
HIST1H2AJ histone cluster 1, H2aj
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
IGKV3-20 immunoglobulin kappa variable 3-20
IL12RB1 interleukin 12 receptor, beta 1
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
LRP5 low density lipoprotein receptor-related protein 5
MAGEF1 melanoma antigen family F1
MBTPS2 membrane-bound transcription factor peptidase, site 2
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial
METRN meteorin, glial cell differentiation regulator
METTL21B methyltransferase like 21B
MTHFSD methenyltetrahydrofolate synthetase domain containing
NAA16 N(alpha)-acetyltransferase 16, NatA auxiliary subunit
NBEAL2 neurobeachin-like 2
NCKAP1L NCK-associated protein 1-like
NCS1 neuronal calcium sensor 1
NOL12 nucleolar protein 12
NPFFR1 neuropeptide FF receptor 1
NPIPB3 nuclear pore complex interacting protein family, member B3
NT5DC3 5'-nucleotidase domain containing 3
PDGFD platelet derived growth factor D
PEX26 peroxisomal biogenesis factor 26
PIEZO1 piezo-type mechanosensitive ion channel component 1
PIGL phosphatidylinositol glycan anchor biosynthesis, class L
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma
PLTP phospholipid transfer protein
POLM polymerase (DNA directed), mu
POTEKP POTE ankyrin domain family, member K, pseudogene
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H
PRKRIP1 PRKR interacting protein 1 (IL11 inducible)
RAB13 RAB13, member RAS oncogene family
RFXAP regulatory factor X-associated protein
RPL23AP7 ribosomal protein L23a pseudogene 7
SERINC5 serine incorporator 5
SERPINI2 serpin peptidase inhibitor, clade I (pancpin), member 2
SH2D3C SH2 domain containing 3C
SIDT1 SID1 transmembrane family, member 1
SKI SKI proto-oncogene
SOX12 SRY (sex determining region Y)-box 12
STX1A syntaxin 1A (brain)
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TBXAS1 thromboxane A synthase 1 (platelet)
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TELO2 telomere maintenance 2
TERT telomerase reverse transcriptase
TET3 tet methylcytosine dioxygenase 3
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast)
TMEM158 transmembrane protein 158 (gene/pseudogene)
TNNT1 troponin T type 1 (skeletal, slow)
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
TRPV6 transient receptor potential cation channel, subfamily V, member 6
UBQLN4 ubiquilin 4
UPK3A uroplakin 3A
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
ZBTB25 zinc finger and BTB domain containing 25
ZDHHC14 zinc finger, DHHC-type containing 14
ZNF506 zinc finger protein 506
ZNF510 zinc finger protein 510
ZNF665 zinc finger protein 665
ZNF696 zinc finger protein 696
ZNF76 zinc finger protein 76
ZSCAN31 zinc finger and SCAN domain containing 31