cloperastine-3710 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the cloperastine-3710 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ACAN aggrecan
ACE angiotensin I converting enzyme
ALK anaplastic lymphoma receptor tyrosine kinase
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2
ART1 ADP-ribosyltransferase 1
ATG10 autophagy related 10
AVPR1B arginine vasopressin receptor 1B
BAIAP3 BAI1-associated protein 3
BEGAIN brain-enriched guanylate kinase-associated
BMP7 bone morphogenetic protein 7
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
C1S complement component 1, s subcomponent
CAPN9 calpain 9
CASP4 caspase 4, apoptosis-related cysteine peptidase
CCL19 chemokine (C-C motif) ligand 19
CCNG2 cyclin G2
CD86 CD86 molecule
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CLDN1 claudin 1
CNTD2 cyclin N-terminal domain containing 2
CNTFR ciliary neurotrophic factor receptor
COL1A1 collagen, type I, alpha 1
COPE coatomer protein complex, subunit epsilon
CPZ carboxypeptidase Z
CSN2 casein beta
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
DAPK1 death-associated protein kinase 1
DDIT3 DNA-damage-inducible transcript 3
DKFZP434C153 DKFZP434C153 protein
EDN3 endothelin 3
EDRF1 erythroid differentiation regulatory factor 1
ENG endoglin
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
EVX1 even-skipped homeobox 1
F2 coagulation factor II (thrombin)
FBXO4 F-box protein 4
FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
GIMAP6 GTPase, IMAP family member 6
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3
GPR15 G protein-coupled receptor 15
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
IGFBP7 insulin-like growth factor binding protein 7
IL6 interleukin 6
INO80D INO80 complex subunit D
IRAK3 interleukin-1 receptor-associated kinase 3
IRF8 interferon regulatory factor 8
ITIH3 inter-alpha-trypsin inhibitor heavy chain 3
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KCNK2 potassium channel, two pore domain subfamily K, member 2
KLF3 Kruppel-like factor 3 (basic)
KLHL18 kelch-like family member 18
LGALS14 lectin, galactoside-binding, soluble, 14
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
LMNA lamin A/C
MATN1 matrilin 1, cartilage matrix protein
MEF2D myocyte enhancer factor 2D
MFAP3L microfibrillar-associated protein 3-like
MLXIPL MLX interacting protein-like
MPPE1 metallophosphoesterase 1
MPZ myelin protein zero
MVD mevalonate (diphospho) decarboxylase
N4BP2L2-IT2 N4BPL2 intronic transcript 2
NKAIN1 Na+/K+ transporting ATPase interacting 1
NLRP3 NLR family, pyrin domain containing 3
OR10J1 olfactory receptor, family 10, subfamily J, member 1
PAX4 paired box 4
PF4 platelet factor 4
PLA2G5 phospholipase A2, group V
PLAC4 placenta-specific 4
PSG1 pregnancy specific beta-1-glycoprotein 1
PSG4 pregnancy specific beta-1-glycoprotein 4
PTPRC protein tyrosine phosphatase, receptor type, C
PURA purine-rich element binding protein A
RAB6B RAB6B, member RAS oncogene family
RCE1 Ras converting CAAX endopeptidase 1
RNF39 ring finger protein 39
RPL18 ribosomal protein L18
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
SDF2L1 stromal cell-derived factor 2-like 1
SIGLEC8 sialic acid binding Ig-like lectin 8
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SOCS7 suppressor of cytokine signaling 7
STC2 stanniocalcin 2
SYT2 synaptotagmin II
TAOK2 TAO kinase 2
TCF20 transcription factor 20 (AR1)
TCP10L t-complex 10-like
TMEM50B transmembrane protein 50B
TRAV8-3 T cell receptor alpha variable 8-3
TRIB3 tribbles pseudokinase 3
TRIL TLR4 interactor with leucine-rich repeats
VCX2 variable charge, X-linked 2
WDR1 WD repeat domain 1
WDR59 WD repeat domain 59
ZIC3 Zic family member 3

decreased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ACTL6A actin-like 6A
ACYP1 acylphosphatase 1, erythrocyte (common) type
AHCTF1 AT hook containing transcription factor 1
ANP32A-IT1 ANP32A intronic transcript 1
APITD1 apoptosis-inducing, TAF9-like domain 1
ASUN asunder spermatogenesis regulator
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
C1ORF159 chromosome 1 open reading frame 159
C22ORF29 chromosome 22 open reading frame 29
C9ORF40 chromosome 9 open reading frame 40
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
CORO2A coronin, actin binding protein, 2A
CRY2 cryptochrome circadian clock 2
CUZD1 CUB and zona pellucida-like domains 1
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1
DNAAF2 dynein, axonemal, assembly factor 2
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
EPHX2 epoxide hydrolase 2, cytoplasmic
ERCC3 excision repair cross-complementation group 3
F2R coagulation factor II (thrombin) receptor
F8 coagulation factor VIII, procoagulant component
FAM50B family with sequence similarity 50, member B
FAM86C1 family with sequence similarity 86, member C1
FANCF Fanconi anemia, complementation group F
FBXL15 F-box and leucine-rich repeat protein 15
FBXL4 F-box and leucine-rich repeat protein 4
GBAS glioblastoma amplified sequence
GLT8D2 glycosyltransferase 8 domain containing 2
GPR1 G protein-coupled receptor 1
GPR4 G protein-coupled receptor 4
GRPR gastrin-releasing peptide receptor
GTF2F2 general transcription factor IIF, polypeptide 2, 30kDa
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
HAS2 hyaluronan synthase 2
HIST1H2AJ histone cluster 1, H2aj
HIST1H4C histone cluster 1, H4c
HOXB5 homeobox B5
HOXC5 homeobox C5
HSPA1A heat shock 70kDa protein 1A
IL33 interleukin 33
IREB2 iron-responsive element binding protein 2
ISOC1 isochorismatase domain containing 1
KIAA1107 KIAA1107
KIF16B kinesin family member 16B
KPTN kaptin (actin binding protein)
LBR lamin B receptor
LINC00341 long intergenic non-protein coding RNA 341
LYPD1 LY6/PLAUR domain containing 1
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast)
MAGEH1 melanoma antigen family H1
MANEA mannosidase, endo-alpha
MBTD1 mbt domain containing 1
MTERF4 mitochondrial transcription termination factor 4
MTG1 mitochondrial ribosome-associated GTPase 1
MTMR6 myotubularin related protein 6
MXD3 MAX dimerization protein 3
NABP2 nucleic acid binding protein 2
NHLRC2 NHL repeat containing 2
NOL6 nucleolar protein 6 (RNA-associated)
NOTCH1 notch 1
NUPL2 nucleoporin like 2
PARP16 poly (ADP-ribose) polymerase family, member 16
PARP3 poly (ADP-ribose) polymerase family, member 3
PCOLCE procollagen C-endopeptidase enhancer
PER3 period circadian clock 3
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PLEKHO1 pleckstrin homology domain containing, family O member 1
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
PPWD1 peptidylprolyl isomerase domain and WD repeat containing 1
PROS1 protein S (alpha)
QTRT1 queuine tRNA-ribosyltransferase 1
RARS arginyl-tRNA synthetase
REV1 REV1, polymerase (DNA directed)
RRN3 RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SCAI suppressor of cancer cell invasion
SCRN3 secernin 3
SEC14L2 SEC14-like 2 (S. cerevisiae)
SECISBP2 SECIS binding protein 2
SEPP1 selenoprotein P, plasma, 1
SLC31A1 solute carrier family 31 (copper transporter), member 1
SLITRK5 SLIT and NTRK-like family, member 5
SNX5 sorting nexin 5
SREK1IP1 SREK1-interacting protein 1
STK25 serine/threonine kinase 25
TCEAL1 transcription elongation factor A (SII)-like 1
TMEM209 transmembrane protein 209
TRIM66 tripartite motif containing 66
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
TTF2 transcription termination factor, RNA polymerase II
TUBGCP5 tubulin, gamma complex associated protein 5
USP27X ubiquitin specific peptidase 27, X-linked
ZNF286A zinc finger protein 286A
ZNF562 zinc finger protein 562
ZNF573 zinc finger protein 573