closed Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

117 genes co-occuring with the biological term closed in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8
ACTN3 actinin, alpha 3 (gene/pseudogene)
ADA adenosine deaminase
ADORA1 adenosine A1 receptor
ADORA2A adenosine A2a receptor
AHCY adenosylhomocysteinase
ANO2 anoctamin 2, calcium activated chloride channel
ASIP agouti signaling protein
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BACE1 beta-site APP-cleaving enzyme 1
BAIAP2 BAI1-associated protein 2
BCAR1 breast cancer anti-estrogen resistance 1
BIRC2 baculoviral IAP repeat containing 2
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B
C3AR1 complement component 3a receptor 1
CAB39 calcium binding protein 39
CACNA1E calcium channel, voltage-dependent, R type, alpha 1E subunit
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CADPS Ca++-dependent secretion activator
CDC42 cell division cycle 42
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CHMP4A charged multivesicular body protein 4A
CSK c-src tyrosine kinase
CXCL12 chemokine (C-X-C motif) ligand 12
DCK deoxycytidine kinase
DCPS decapping enzyme, scavenger
DDX19B DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B
DMD dystrophin
ELN elastin
EPHB4 EPH receptor B4
ERAP1 endoplasmic reticulum aminopeptidase 1
ESR1 estrogen receptor 1
F10 coagulation factor X
FDPS farnesyl diphosphate synthase
FLT3 fms-related tyrosine kinase 3
FNBP1L formin binding protein 1-like
GCK glucokinase (hexokinase 4)
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GJA1 gap junction protein, alpha 1, 43kDa
GJB2 gap junction protein, beta 2, 26kDa
GLI1 GLI family zinc finger 1
GLRA1 glycine receptor, alpha 1
GPC3 glypican 3
GRIA1 glutamate receptor, ionotropic, AMPA 1
GRIK2 glutamate receptor, ionotropic, kainate 2
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSPA4 heat shock 70kDa protein 4
IFNAR1 interferon (alpha, beta and omega) receptor 1
IFNAR2 interferon (alpha, beta and omega) receptor 2
IGF1 insulin-like growth factor 1 (somatomedin C)
IL2 interleukin 2
IRAK1 interleukin-1 receptor-associated kinase 1
IRF7 interferon regulatory factor 7
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
KCNA2 potassium channel, voltage gated shaker related subfamily A, member 2
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KCNH5 potassium channel, voltage gated eag related subfamily H, member 5
KCNJ1 potassium channel, inwardly rectifying subfamily J, member 1
KCNJ11 potassium channel, inwardly rectifying subfamily J, member 11
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1
KPNA1 karyopherin alpha 1 (importin alpha 5)
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast)
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast)
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MYC v-myc avian myelocytomatosis viral oncogene homolog
NF2 neurofibromin 2 (merlin)
NLRC5 NLR family, CARD domain containing 5
NLRP3 NLR family, pyrin domain containing 3
NOS1 nitric oxide synthase 1 (neuronal)
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
NT5E 5'-nucleotidase, ecto (CD73)
NUP50 nucleoporin 50kDa
PCNA proliferating cell nuclear antigen
PDCD6IP programmed cell death 6 interacting protein
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PLA2R1 phospholipase A2 receptor 1, 180kDa
PLG plasminogen
POLM polymerase (DNA directed), mu
PRKCA protein kinase C, alpha
PTPN11 protein tyrosine phosphatase, non-receptor type 11
RAD23A RAD23 homolog A (S. cerevisiae)
RARB retinoic acid receptor, beta
RARG retinoic acid receptor, gamma
RNF20 ring finger protein 20, E3 ubiquitin protein ligase
RYR2 ryanodine receptor 2 (cardiac)
S100A16 S100 calcium binding protein A16
S100B S100 calcium binding protein B
SCN5A sodium channel, voltage gated, type V alpha subunit
SH2D3C SH2 domain containing 3C
SLC18A3 solute carrier family 18 (vesicular acetylcholine transporter), member 3
SPTA1 spectrin, alpha, erythrocytic 1
STIM1 stromal interaction molecule 1
STK11 serine/threonine kinase 11
STRADA STE20-related kinase adaptor alpha
STX1A syntaxin 1A (brain)
SUFU suppressor of fused homolog (Drosophila)
TERF1 telomeric repeat binding factor (NIMA-interacting) 1
TES testin LIM domain protein
TF transferrin
TGM2 transglutaminase 2
TMEM173 transmembrane protein 173
TMEM18 transmembrane protein 18
TNNC1 troponin C type 1 (slow)
TOP1 topoisomerase (DNA) I
TP53 tumor protein p53
TPM2 tropomyosin 2 (beta)
TRPV1 transient receptor potential cation channel, subfamily V, member 1
UBE2D3 ubiquitin-conjugating enzyme E2D 3
UBE2N ubiquitin-conjugating enzyme E2N
UPP1 uridine phosphorylase 1
VAMP7 vesicle-associated membrane protein 7
VCL vinculin