clotrimazole-6207 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the clotrimazole-6207 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AEN apoptosis enhancing nuclease
AP2A2 adaptor-related protein complex 2, alpha 2 subunit
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
ARC activity-regulated cytoskeleton-associated protein
ASNS asparagine synthetase (glutamine-hydrolyzing)
ATF3 activating transcription factor 3
ATF7IP2 activating transcription factor 7 interacting protein 2
ATM ATM serine/threonine kinase
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide
B9D1 B9 protein domain 1
BTN2A1 butyrophilin, subfamily 2, member A1
C22ORF46 chromosome 22 open reading frame 46
C7ORF43 chromosome 7 open reading frame 43
CACNB3 calcium channel, voltage-dependent, beta 3 subunit
CASP5 caspase 5, apoptosis-related cysteine peptidase
CCL13 chemokine (C-C motif) ligand 13
CCPG1 cell cycle progression 1
CD52 CD52 molecule
CFLAR CASP8 and FADD-like apoptosis regulator
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHKB choline kinase beta
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5
CIITA class II, major histocompatibility complex, transactivator
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DHRS2 dehydrogenase/reductase (SDR family) member 2
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DPYS dihydropyrimidinase
DUSP1 dual specificity phosphatase 1
DUSP4 dual specificity phosphatase 4
DYNC2LI1 dynein, cytoplasmic 2, light intermediate chain 1
EGR1 early growth response 1
EML3 echinoderm microtubule associated protein like 3
EPHA2 EPH receptor A2
FGFR2 fibroblast growth factor receptor 2
FLI1 Fli-1 proto-oncogene, ETS transcription factor
FLJ11292
GADD45A growth arrest and DNA-damage-inducible, alpha
GADD45G growth arrest and DNA-damage-inducible, gamma
GAMT guanidinoacetate N-methyltransferase
GGPS1 geranylgeranyl diphosphate synthase 1
GLTSCR1 glioma tumor suppressor candidate region gene 1
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HMOX1 heme oxygenase 1
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFT54 intraflagellar transport 54
IGHD immunoglobulin heavy constant delta
IL23A interleukin 23, alpha subunit p19
INHBE inhibin, beta E
IRF6 interferon regulatory factor 6
JRK Jrk homolog (mouse)
KCNH6 potassium channel, voltage gated eag related subfamily H, member 6
LDB1 LIM domain binding 1
LOC399491
LPAR4 lysophosphatidic acid receptor 4
LRRC41 leucine rich repeat containing 41
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MED13L mediator complex subunit 13-like
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTMR3 myotubularin related protein 3
MUL1 mitochondrial E3 ubiquitin protein ligase 1
N4BP2L2 NEDD4 binding protein 2-like 2
NR4A1 nuclear receptor subfamily 4, group A, member 1
NR4A2 nuclear receptor subfamily 4, group A, member 2
NUPR1 nuclear protein, transcriptional regulator, 1
OCA2 oculocutaneous albinism II
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
POMT2 protein-O-mannosyltransferase 2
RASAL1 RAS protein activator like 1 (GAP1 like)
RNF19B ring finger protein 19B
RPGR retinitis pigmentosa GTPase regulator
RTN2 reticulon 2
SCN10A sodium channel, voltage gated, type X alpha subunit
SEC63 SEC63 homolog (S. cerevisiae)
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
SH2B3 SH2B adaptor protein 3
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SNAPC5 small nuclear RNA activating complex, polypeptide 5, 19kDa
SPAG8 sperm associated antigen 8
SPATA1 spermatogenesis associated 1
SPINK5 serine peptidase inhibitor, Kazal type 5
SUGP1 SURP and G patch domain containing 1
SYNGR1 synaptogyrin 1
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TPMT thiopurine S-methyltransferase
TRIM2 tripartite motif containing 2
TRPC5 transient receptor potential cation channel, subfamily C, member 5
VEGFA vascular endothelial growth factor A
VLDLR very low density lipoprotein receptor
WIPI1 WD repeat domain, phosphoinositide interacting 1
ZNF350 zinc finger protein 350
ZNF592 zinc finger protein 592
ZNF701 zinc finger protein 701

decreased expression

Symbol Name
ACVR2A activin A receptor, type IIA
AMDHD2 amidohydrolase domain containing 2
AXIN1 axin 1
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
BCCIP BRCA2 and CDKN1A interacting protein
BRD9 bromodomain containing 9
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3
C10ORF88 chromosome 10 open reading frame 88
C2ORF44 chromosome 2 open reading frame 44
C5ORF45 chromosome 5 open reading frame 45
CAPG capping protein (actin filament), gelsolin-like
CCNE2 cyclin E2
CENPI centromere protein I
CLP1 cleavage and polyadenylation factor I subunit 1
CPNE1 copine I
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
EGLN3 egl-9 family hypoxia-inducible factor 3
EIF5A2 eukaryotic translation initiation factor 5A2
ERCC5 excision repair cross-complementation group 5
ERCC6L excision repair cross-complementation group 6-like
FAM114A2 family with sequence similarity 114, member A2
FAM160B2 family with sequence similarity 160, member B2
FBXL4 F-box and leucine-rich repeat protein 4
FOXRED2 FAD-dependent oxidoreductase domain containing 2
FZD3 frizzled class receptor 3
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GDAP1 ganglioside induced differentiation associated protein 1
GHR growth hormone receptor
GJA1 gap junction protein, alpha 1, 43kDa
GLB1L2 galactosidase, beta 1-like 2
GMCL1 germ cell-less, spermatogenesis associated 1
GMEB1 glucocorticoid modulatory element binding protein 1
GPR19 G protein-coupled receptor 19
H2AFY2 H2A histone family, member Y2
HAUS6 HAUS augmin-like complex, subunit 6
HMHA1 histocompatibility (minor) HA-1
HPS6 Hermansky-Pudlak syndrome 6
HSPA2 heat shock 70kDa protein 2
IFT81 intraflagellar transport 81
INO80D INO80 complex subunit D
INPPL1 inositol polyphosphate phosphatase-like 1
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KIF3A kinesin family member 3A
LMNB1 lamin B1
LRRC49 leucine rich repeat containing 49
LYPD1 LY6/PLAUR domain containing 1
MAMLD1 mastermind-like domain containing 1
MAPK12 mitogen-activated protein kinase 12
MCOLN3 mucolipin 3
MCRS1 microspherule protein 1
MORC3 MORC family CW-type zinc finger 3
MRPL44 mitochondrial ribosomal protein L44
NES nestin
NPL N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)
NPM3 nucleophosmin/nucleoplasmin 3
OLFML3 olfactomedin-like 3
ORC1 origin recognition complex, subunit 1
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1
PLEK2 pleckstrin 2
POMZP3 POM121 and ZP3 fusion
PPP6R2 protein phosphatase 6, regulatory subunit 2
PRMT7 protein arginine methyltransferase 7
PSKH1 protein serine kinase H1
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAB4B RAB4B, member RAS oncogene family
RFWD3 ring finger and WD repeat domain 3
RGS19 regulator of G-protein signaling 19
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RINT1 RAD50 interactor 1
RLF rearranged L-myc fusion
RPL23AP7 ribosomal protein L23a pseudogene 7
SETD8 SET domain containing (lysine methyltransferase) 8
SIRT2 sirtuin 2
SLC27A6 solute carrier family 27 (fatty acid transporter), member 6
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SNIP1 Smad nuclear interacting protein 1
SSFA2 sperm specific antigen 2
STARD13 StAR-related lipid transfer (START) domain containing 13
STBD1 starch binding domain 1
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TNNT1 troponin T type 1 (skeletal, slow)
TPST2 tyrosylprotein sulfotransferase 2
TSPAN1 tetraspanin 1
TTC26 tetratricopeptide repeat domain 26
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast)
VAV1 vav 1 guanine nucleotide exchange factor
VSIG10 V-set and immunoglobulin domain containing 10
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
XYLT2 xylosyltransferase II
ZBTB38 zinc finger and BTB domain containing 38
ZC3H12A zinc finger CCCH-type containing 12A
ZFYVE16 zinc finger, FYVE domain containing 16
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF143 zinc finger protein 143
ZNF276 zinc finger protein 276
ZNF668 zinc finger protein 668
ZNF675 zinc finger protein 675