cloxacillin-1443 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the cloxacillin-1443 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACRV1 acrosomal vesicle protein 1
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
AP3S2 adaptor-related protein complex 3, sigma 2 subunit
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ASTE1 asteroid homolog 1 (Drosophila)
ATAD2B ATPase family, AAA domain containing 2B
BAD BCL2-associated agonist of cell death
BLVRA biliverdin reductase A
BTG2 BTG family, member 2
C19ORF66 chromosome 19 open reading frame 66
C21ORF91 chromosome 21 open reading frame 91
CANT1 calcium activated nucleotidase 1
CCDC71 coiled-coil domain containing 71
CREM cAMP responsive element modulator
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like
CTNND1 catenin (cadherin-associated protein), delta 1
CXCR3 chemokine (C-X-C motif) receptor 3
CYB561 cytochrome b561
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11
DUS2 dihydrouridine synthase 2
DUSP3 dual specificity phosphatase 3
ELMO2 engulfment and cell motility 2
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
ERN2 endoplasmic reticulum to nucleus signaling 2
ETNK1 ethanolamine kinase 1
FBXO42 F-box protein 42
FCGRT Fc fragment of IgG, receptor, transporter, alpha
FMOD fibromodulin
G0S2 G0/G1 switch 2
G6PC3 glucose 6 phosphatase, catalytic, 3
GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1
GLOD4 glyoxalase domain containing 4
GML glycosylphosphatidylinositol anchored molecule like
GPRIN2 G protein regulated inducer of neurite outgrowth 2
IDS iduronate 2-sulfatase
IL27RA interleukin 27 receptor, alpha
INHBC inhibin, beta C
IRF4 interferon regulatory factor 4
ITSN2 intersectin 2
KATNB1 katanin p80 (WD repeat containing) subunit B 1
KCTD2 potassium channel tetramerization domain containing 2
KIAA1045 KIAA1045
KRT75 keratin 75, type II
LBP lipopolysaccharide binding protein
LDOC1 leucine zipper, down-regulated in cancer 1
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
LINC00574 long intergenic non-protein coding RNA 574
LMO3 LIM domain only 3 (rhombotin-like 2)
MAML3 mastermind-like 3 (Drosophila)
MAN1B1 mannosidase, alpha, class 1B, member 1
MAPK10 mitogen-activated protein kinase 10
MECP2 methyl CpG binding protein 2
MED16 mediator complex subunit 16
MINK1 misshapen-like kinase 1
MPPE1 metallophosphoesterase 1
NDNF neuron-derived neurotrophic factor
NOP16 NOP16 nucleolar protein
NOTCH1 notch 1
NR4A1 nuclear receptor subfamily 4, group A, member 1
OR2S2 olfactory receptor, family 2, subfamily S, member 2 (gene/pseudogene)
PADI1 peptidyl arginine deiminase, type I
PCSK6 proprotein convertase subtilisin/kexin type 6
PDLIM7 PDZ and LIM domain 7 (enigma)
PHLPP2 PH domain and leucine rich repeat protein phosphatase 2
POLR2F polymerase (RNA) II (DNA directed) polypeptide F
PPP1R12A protein phosphatase 1, regulatory subunit 12A
PPP2R2B protein phosphatase 2, regulatory subunit B, beta
PRY PTPN13-like, Y-linked
PTK2 protein tyrosine kinase 2
RHOH ras homolog family member H
RPA4 replication protein A4, 30kDa
RPAP2 RNA polymerase II associated protein 2
RPL10 ribosomal protein L10
RTF1 Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
S1PR4 sphingosine-1-phosphate receptor 4
SIGLEC5 sialic acid binding Ig-like lectin 5
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
SMIM8 small integral membrane protein 8
SPON1 spondin 1, extracellular matrix protein
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
SRR serine racemase
SRSF8 serine/arginine-rich splicing factor 8
ST5 suppression of tumorigenicity 5
STAM2 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
STK38L serine/threonine kinase 38 like
TFCP2L1 transcription factor CP2-like 1
TLE2 transducin-like enhancer of split 2
TMPRSS5 transmembrane protease, serine 5
TPSG1 tryptase gamma 1
TTC26 tetratricopeptide repeat domain 26
TTC3 tetratricopeptide repeat domain 3
TUBB3 tubulin, beta 3 class III
WHSC1L1 Wolf-Hirschhorn syndrome candidate 1-like 1
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
ZC3HAV1 zinc finger CCCH-type, antiviral 1
ZNF280D zinc finger protein 280D
ZNF318 zinc finger protein 318

decreased expression

Symbol Name
ANKRD28 ankyrin repeat domain 28
ANKRD36B ankyrin repeat domain 36B
ARGLU1 arginine and glutamate rich 1
ATAT1 alpha tubulin acetyltransferase 1
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
ATXN2 ataxin 2
BCL10 B-cell CLL/lymphoma 10
C1ORF27 chromosome 1 open reading frame 27
C3AR1 complement component 3a receptor 1
CALCOCO1 calcium binding and coiled-coil domain 1
CBLL1 Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase
CBR1 carbonyl reductase 1
CD248 CD248 molecule, endosialin
CER1 cerberus 1, DAN family BMP antagonist
CFAP74 cilia and flagella associated protein 74
CLDN15 claudin 15
CLTCL1 clathrin, heavy chain-like 1
COL4A3BP collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
CRIPT cysteine-rich PDZ-binding protein
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DAZAP1 DAZ associated protein 1
DPH2 DPH2 homolog (S. cerevisiae)
EGLN2 egl-9 family hypoxia-inducible factor 2
ENAH enabled homolog (Drosophila)
ERF Ets2 repressor factor
EXOSC9 exosome component 9
FOS FBJ murine osteosarcoma viral oncogene homolog
GALNT11 polypeptide N-acetylgalactosaminyltransferase 11
GALR3 galanin receptor 3
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C
GIMAP6 GTPase, IMAP family member 6
GIN1 gypsy retrotransposon integrase 1
GTF2H4 general transcription factor IIH, polypeptide 4, 52kDa
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
GUSBP3 glucuronidase, beta pseudogene 3
HAAO 3-hydroxyanthranilate 3,4-dioxygenase
HIRA histone cell cycle regulator
HIST1H1C histone cluster 1, H1c
HMGB3P1 high mobility group box 3 pseudogene 1
HS1BP3 HCLS1 binding protein 3
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IGKV1D-13 immunoglobulin kappa variable 1D-13
INPPL1 inositol polyphosphate phosphatase-like 1
JUNB jun B proto-oncogene
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KIAA1598
KIFC1 kinesin family member C1
KLHL21 kelch-like family member 21
MAGOHB mago-nashi homolog B (Drosophila)
MED22 mediator complex subunit 22
MED9 mediator complex subunit 9
MITF microphthalmia-associated transcription factor
MOB3B MOB kinase activator 3B
MORC3 MORC family CW-type zinc finger 3
MPC1 mitochondrial pyruvate carrier 1
NRGN neurogranin (protein kinase C substrate, RC3)
NRN1 neuritin 1
NUPL1 nucleoporin like 1
NXPH3 neurexophilin 3
PAK1IP1 PAK1 interacting protein 1
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1
PJA1 praja ring finger 1, E3 ubiquitin protein ligase
PLA2G12A phospholipase A2, group XIIA
PTBP2 polypyrimidine tract binding protein 2
QPRT quinolinate phosphoribosyltransferase
RAB4B RAB4B, member RAS oncogene family
RABEPK Rab9 effector protein with kelch motifs
RBM22 RNA binding motif protein 22
RECQL4 RecQ protein-like 4
RFPL3 ret finger protein-like 3
RGP1 RGP1 retrograde golgi transport homolog (S. cerevisiae)
RP2 retinitis pigmentosa 2 (X-linked recessive)
RPS4Y1 ribosomal protein S4, Y-linked 1
RSF1 remodeling and spacing factor 1
SETD8 SET domain containing (lysine methyltransferase) 8
SH3GL1 SH3-domain GRB2-like 1
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7
SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22
SPI1 Spi-1 proto-oncogene
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TMEM134 transmembrane protein 134
TMEM184C transmembrane protein 184C
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRIM52 tripartite motif containing 52
TSEN2 TSEN2 tRNA splicing endonuclease subunit
UBE2O ubiquitin-conjugating enzyme E2O
UPF3B UPF3 regulator of nonsense transcripts homolog B (yeast)
WDR41 WD repeat domain 41
WDR91 WD repeat domain 91
ZBTB48 zinc finger and BTB domain containing 48
ZNF107 zinc finger protein 107
ZNF140 zinc finger protein 140
ZNF175 zinc finger protein 175
ZNF184 zinc finger protein 184
ZNF189 zinc finger protein 189
ZNF606 zinc finger protein 606
ZNF652 zinc finger protein 652
ZSCAN9 zinc finger and SCAN domain containing 9