cloxacillin-2289 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the cloxacillin-2289 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM12 ADAM metallopeptidase domain 12
ADAM29 ADAM metallopeptidase domain 29
ADCK2 aarF domain containing kinase 2
AKT2 v-akt murine thymoma viral oncogene homolog 2
AQP1 aquaporin 1 (Colton blood group)
ARNT aryl hydrocarbon receptor nuclear translocator
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
BAZ2A bromodomain adjacent to zinc finger domain, 2A
C10ORF95 chromosome 10 open reading frame 95
C19ORF57 chromosome 19 open reading frame 57
CA9 carbonic anhydrase IX
CABP2 calcium binding protein 2
CADM4 cell adhesion molecule 4
CASP10 caspase 10, apoptosis-related cysteine peptidase
CASP2 caspase 2, apoptosis-related cysteine peptidase
CD248 CD248 molecule, endosialin
CD47 CD47 molecule
CD79B CD79b molecule, immunoglobulin-associated beta
CDRT1 CMT1A duplicated region transcript 1
CEL carboxyl ester lipase
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CIDEC cell death-inducing DFFA-like effector c
CLCA2 chloride channel accessory 2
CLEC4E C-type lectin domain family 4, member E
CLTC clathrin, heavy chain (Hc)
COBLL1 cordon-bleu WH2 repeat protein-like 1
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1
DAPK3 death-associated protein kinase 3
DNASE1L3 deoxyribonuclease I-like 3
DPF3 D4, zinc and double PHD fingers, family 3
DTNB dystrobrevin, beta
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2
F2RL3 coagulation factor II (thrombin) receptor-like 3
FOXP3 forkhead box P3
GADD45GIP1 growth arrest and DNA-damage-inducible, gamma interacting protein 1
GPER1 G protein-coupled estrogen receptor 1
GSK3A glycogen synthase kinase 3 alpha
GTDC1 glycosyltransferase-like domain containing 1
GYPB glycophorin B (MNS blood group)
HAAO 3-hydroxyanthranilate 3,4-dioxygenase
HCFC1 host cell factor C1
HIST1H1D histone cluster 1, H1d
HTR6 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
IFNA16 interferon, alpha 16
IL11RA interleukin 11 receptor, alpha
ING4 inhibitor of growth family, member 4
KCNH6 potassium channel, voltage gated eag related subfamily H, member 6
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KLF13 Kruppel-like factor 13
LINC00652 long intergenic non-protein coding RNA 652
LRRC6 leucine rich repeat containing 6
LYZL6 lysozyme-like 6
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP3 matrix metallopeptidase 3
MMP8 matrix metallopeptidase 8
MUC3B mucin 3B, cell surface associated
MVB12B multivesicular body subunit 12B
NNAT neuronatin
OR2B6 olfactory receptor, family 2, subfamily B, member 6
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
PIPOX pipecolic acid oxidase
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene
POU4F1 POU class 4 homeobox 1
PQLC2 PQ loop repeat containing 2
PRODH2 proline dehydrogenase (oxidase) 2
PTPN21 protein tyrosine phosphatase, non-receptor type 21
PTPRJ protein tyrosine phosphatase, receptor type, J
REC8 REC8 meiotic recombination protein
RUNX1 runt-related transcription factor 1
SAFB scaffold attachment factor B
SH3GL3 SH3-domain GRB2-like 3
SHOX2 short stature homeobox 2
SIRPB1 signal-regulatory protein beta 1
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SRP72 signal recognition particle 72kDa
STEAP4 STEAP family member 4
TBX5 T-box 5
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TLDC1 TBC/LysM-associated domain containing 1
TMEFF1 transmembrane protein with EGF-like and two follistatin-like domains 1
TMEM209 transmembrane protein 209
TMEM63A transmembrane protein 63A
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TP53I11 tumor protein p53 inducible protein 11
TSC22D2 TSC22 domain family, member 2
TUBA3C tubulin, alpha 3c
USP2 ubiquitin specific peptidase 2
WNT10B wingless-type MMTV integration site family, member 10B
WNT16 wingless-type MMTV integration site family, member 16
ZFP64 ZFP64 zinc finger protein
ZNF197 zinc finger protein 197
ZNF235 zinc finger protein 235
ZNF286A zinc finger protein 286A
ZNF3 zinc finger protein 3
ZNF44 zinc finger protein 44
ZNF518A zinc finger protein 518A

decreased expression

Symbol Name
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12
ADAMTS20 ADAM metallopeptidase with thrombospondin type 1 motif, 20
AHSP alpha hemoglobin stabilizing protein
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ANKFY1 ankyrin repeat and FYVE domain containing 1
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ATF7IP2 activating transcription factor 7 interacting protein 2
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
BMP4 bone morphogenetic protein 4
C11ORF21 chromosome 11 open reading frame 21
C3 complement component 3
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCDC71 coiled-coil domain containing 71
CCP110 centriolar coiled coil protein 110kDa
CFAP45 cilia and flagella associated protein 45
CHRM3 cholinergic receptor, muscarinic 3
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
CNGB3 cyclic nucleotide gated channel beta 3
CNTN1 contactin 1
CRELD1 cysteine-rich with EGF-like domains 1
CST6 cystatin E/M
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1
DDIT3 DNA-damage-inducible transcript 3
DPY19L1P1 DPY19L1 pseudogene 1
DSCAM Down syndrome cell adhesion molecule
ELP6 elongator acetyltransferase complex subunit 6
ELSPBP1 epididymal sperm binding protein 1
EMCN endomucin
ERCC4 excision repair cross-complementation group 4
EXOC6B exocyst complex component 6B
FAM76A family with sequence similarity 76, member A
FLJ11710 uncharacterized protein FLJ11710
FLT4 fms-related tyrosine kinase 4
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GFI1 growth factor independent 1 transcription repressor
GLRA1 glycine receptor, alpha 1
GNG13 guanine nucleotide binding protein (G protein), gamma 13
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GPR143 G protein-coupled receptor 143
GSTCD glutathione S-transferase, C-terminal domain containing
GUSBP3 glucuronidase, beta pseudogene 3
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HIST1H2AI histone cluster 1, H2ai
HIST1H2BO histone cluster 1, H2bo
HIST1H3B histone cluster 1, H3b
HMOX1 heme oxygenase 1
IPO8 importin 8
JPH3 junctophilin 3
KCTD17 potassium channel tetramerization domain containing 17
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1
MALL mal, T-cell differentiation protein-like
MLLT4-AS1 MLLT4 antisense RNA 1 (head to head)
MYF5 myogenic factor 5
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
OVGP1 oviductal glycoprotein 1, 120kDa
P2RY4 pyrimidinergic receptor P2Y, G-protein coupled, 4
PAIP2B poly(A) binding protein interacting protein 2B
PARP16 poly (ADP-ribose) polymerase family, member 16
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PLXNA3 plexin A3
POMT2 protein-O-mannosyltransferase 2
PPP1R9A protein phosphatase 1, regulatory subunit 9A
PPT2 palmitoyl-protein thioesterase 2
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
QSER1 glutamine and serine rich 1
RNF2 ring finger protein 2
RNF39 ring finger protein 39
RNF43 ring finger protein 43
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
SAYSD1 SAYSVFN motif domain containing 1
SCGB2A2 secretoglobin, family 2A, member 2
SCN1B sodium channel, voltage gated, type I beta subunit
SCRN3 secernin 3
SGCE sarcoglycan, epsilon
SIPA1 signal-induced proliferation-associated 1
SLC44A1 solute carrier family 44 (choline transporter), member 1
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SPTBN2 spectrin, beta, non-erythrocytic 2
TBC1D17 TBC1 domain family, member 17
TBKBP1 TBK1 binding protein 1
THNSL2 threonine synthase-like 2 (S. cerevisiae)
THRAP3 thyroid hormone receptor associated protein 3
TMLHE trimethyllysine hydroxylase, epsilon
TPCN1 two pore segment channel 1
TRMT44 tRNA methyltransferase 44 homolog (S. cerevisiae)
TSNAXIP1 translin-associated factor X interacting protein 1
VPS9D1 VPS9 domain containing 1
WLS wntless Wnt ligand secretion mediator
XDH xanthine dehydrogenase
YY2 YY2 transcription factor
ZFHX2 zinc finger homeobox 2
ZIM2 zinc finger, imprinted 2
ZNF219 zinc finger protein 219
ZNF665 zinc finger protein 665
ZNF747 zinc finger protein 747
ZNF862 zinc finger protein 862