Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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198 genes differentially expressed following the clozapine-1009 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
ACVR1B | activin A receptor, type IB |
ALOX15 | arachidonate 15-lipoxygenase |
ALS2CL | ALS2 C-terminal like |
ARHGAP33 | Rho GTPase activating protein 33 |
ARHGEF11 | Rho guanine nucleotide exchange factor (GEF) 11 |
ARRB1 | arrestin, beta 1 |
B3GNT3 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 |
BCL6 | B-cell CLL/lymphoma 6 |
BICD1 | bicaudal D homolog 1 (Drosophila) |
BMP2K | BMP2 inducible kinase |
BMP5 | bone morphogenetic protein 5 |
CD6 | CD6 molecule |
CLUHP3 | clustered mitochondria (cluA/CLU1) homolog pseudogene 3 |
CNGA1 | cyclic nucleotide gated channel alpha 1 |
CNKSR1 | connector enhancer of kinase suppressor of Ras 1 |
CUL9 | cullin 9 |
CYP1A2 | cytochrome P450, family 1, subfamily A, polypeptide 2 |
DIMT1 | DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae) |
DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
DOHH | deoxyhypusine hydroxylase/monooxygenase |
DTX2P1-UPK3BP1-PMS2P11 | DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene |
ETNK2 | ethanolamine kinase 2 |
F11R | F11 receptor |
FADS3 | fatty acid desaturase 3 |
FAM214B | family with sequence similarity 214, member B |
FGD1 | FYVE, RhoGEF and PH domain containing 1 |
GABBR2 | gamma-aminobutyric acid (GABA) B receptor, 2 |
GBP2 | guanylate binding protein 2, interferon-inducible |
GJA9 | gap junction protein, alpha 9, 59kDa |
GNAT2 | guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 |
GPC4 | glypican 4 |
HIST1H2BC | histone cluster 1, H2bc |
HMGN5 | high mobility group nucleosome binding domain 5 |
HOXC10 | homeobox C10 |
HRASLS2 | HRAS-like suppressor 2 |
IFT140 | intraflagellar transport 140 |
JAG1 | jagged 1 |
JAK2 | Janus kinase 2 |
JMJD6 | jumonji domain containing 6 |
KBTBD11 | kelch repeat and BTB (POZ) domain containing 11 |
KDELR3 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 |
LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 |
LUZP1 | leucine zipper protein 1 |
LYRM9 | LYR motif containing 9 |
MAN2C1 | mannosidase, alpha, class 2C, member 1 |
MGC12488 | |
MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 |
MSR1 | macrophage scavenger receptor 1 |
NME5 | NME/NM23 family member 5 |
NUP214 | nucleoporin 214kDa |
OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
PADI1 | peptidyl arginine deiminase, type I |
PDE12 | phosphodiesterase 12 |
PDE4DIP | phosphodiesterase 4D interacting protein |
PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
PLSCR3 | phospholipid scramblase 3 |
PNMAL1 | paraneoplastic Ma antigen family-like 1 |
PPARD | peroxisome proliferator-activated receptor delta |
PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) |
PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
PTCRA | pre T-cell antigen receptor alpha |
PTK6 | protein tyrosine kinase 6 |
RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
RAB40AL | RAB40A, member RAS oncogene family-like |
RAD51B | RAD51 paralog B |
RAD51D | RAD51 paralog D |
RCHY1 | ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase |
RDH11 | retinol dehydrogenase 11 (all-trans/9-cis/11-cis) |
RIMS3 | regulating synaptic membrane exocytosis 3 |
RPS6KA4 | ribosomal protein S6 kinase, 90kDa, polypeptide 4 |
RSPH14 | radial spoke head 14 homolog (Chlamydomonas) |
SAPCD1 | suppressor APC domain containing 1 |
SEMA4G | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G |
SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 |
SFTPB | surfactant protein B |
SGSM2 | small G protein signaling modulator 2 |
SH3BP2 | SH3-domain binding protein 2 |
SIDT2 | SID1 transmembrane family, member 2 |
SLC25A21 | solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 |
SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
SLC4A8 | solute carrier family 4, sodium bicarbonate cotransporter, member 8 |
SOAT2 | sterol O-acyltransferase 2 |
STC1 | stanniocalcin 1 |
STMN3 | stathmin-like 3 |
SUGP1 | SURP and G patch domain containing 1 |
TAF9B | TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa |
TARP | TCR gamma alternate reading frame protein |
TCP11L1 | t-complex 11, testis-specific-like 1 |
THNSL2 | threonine synthase-like 2 (S. cerevisiae) |
TRPC1 | transient receptor potential cation channel, subfamily C, member 1 |
TSPYL2 | TSPY-like 2 |
TTC28 | tetratricopeptide repeat domain 28 |
TTLL3 | tubulin tyrosine ligase-like family member 3 |
VEGFA | vascular endothelial growth factor A |
WDR25 | WD repeat domain 25 |
ZFP36L2 | ZFP36 ring finger protein-like 2 |
ZHX3 | zinc fingers and homeoboxes 3 |
ZNF589 | zinc finger protein 589 |
ZNF76 | zinc finger protein 76 |
ZNF862 | zinc finger protein 862 |
Symbol | Name |
---|---|
ACSL4 | acyl-CoA synthetase long-chain family member 4 |
ALOX12P2 | arachidonate 12-lipoxygenase pseudogene 2 |
ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta |
ARID3B | AT rich interactive domain 3B (BRIGHT-like) |
BAHD1 | bromo adjacent homology domain containing 1 |
BBS7 | Bardet-Biedl syndrome 7 |
BMP4 | bone morphogenetic protein 4 |
C11ORF73 | chromosome 11 open reading frame 73 |
C11ORF95 | chromosome 11 open reading frame 95 |
C21ORF91 | chromosome 21 open reading frame 91 |
C7ORF43 | chromosome 7 open reading frame 43 |
CAPG | capping protein (actin filament), gelsolin-like |
CAPN15 | calpain 15 |
CD302 | CD302 molecule |
CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
CORO2A | coronin, actin binding protein, 2A |
CRABP1 | cellular retinoic acid binding protein 1 |
CRYBB2P1 | crystallin, beta B2 pseudogene 1 |
CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 |
CUEDC1 | CUE domain containing 1 |
CWC25 | CWC25 spliceosome-associated protein homolog (S. cerevisiae) |
CYP20A1 | cytochrome P450, family 20, subfamily A, polypeptide 1 |
DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 |
DGKE | diacylglycerol kinase, epsilon 64kDa |
DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 |
EIF5A2 | eukaryotic translation initiation factor 5A2 |
FBXL6 | F-box and leucine-rich repeat protein 6 |
FKBP8 | FK506 binding protein 8, 38kDa |
FOXRED2 | FAD-dependent oxidoreductase domain containing 2 |
FUZ | fuzzy planar cell polarity protein |
GALK1 | galactokinase 1 |
GCHFR | GTP cyclohydrolase I feedback regulator |
GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 |
GDAP1 | ganglioside induced differentiation associated protein 1 |
GNB1L | guanine nucleotide binding protein (G protein), beta polypeptide 1-like |
GUSBP3 | glucuronidase, beta pseudogene 3 |
HEY2 | hes-related family bHLH transcription factor with YRPW motif 2 |
HOOK1 | hook microtubule-tethering protein 1 |
HYI | hydroxypyruvate isomerase (putative) |
IRF7 | interferon regulatory factor 7 |
ITPKB | inositol-trisphosphate 3-kinase B |
ITPKC | inositol-trisphosphate 3-kinase C |
LCP1 | lymphocyte cytosolic protein 1 (L-plastin) |
LOC202181 | SUMO-interacting motifs containing 1 pseudogene |
LRRC61 | leucine rich repeat containing 61 |
LYPLA2P1 | lysophospholipase II pseudogene 1 |
MAGOHB | mago-nashi homolog B (Drosophila) |
MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase |
MAP3K6 | mitogen-activated protein kinase kinase kinase 6 |
MDM4 | MDM4, p53 regulator |
MFSD11 | major facilitator superfamily domain containing 11 |
MMACHC | methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria |
MT1H | metallothionein 1H |
MTG1 | mitochondrial ribosome-associated GTPase 1 |
MTMR12 | myotubularin related protein 12 |
MVD | mevalonate (diphospho) decarboxylase |
MXD3 | MAX dimerization protein 3 |
MYBBP1A | MYB binding protein (P160) 1a |
NDE1 | nudE neurodevelopment protein 1 |
NRGN | neurogranin (protein kinase C substrate, RC3) |
NUS1P3 | nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3 |
PAQR3 | progestin and adipoQ receptor family member III |
PDZRN3 | PDZ domain containing ring finger 3 |
PIBF1 | progesterone immunomodulatory binding factor 1 |
PIM1 | Pim-1 proto-oncogene, serine/threonine kinase |
PNPLA6 | patatin-like phospholipase domain containing 6 |
PPM1E | protein phosphatase, Mg2+/Mn2+ dependent, 1E |
PSTPIP2 | proline-serine-threonine phosphatase interacting protein 2 |
RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 |
RFTN1 | raftlin, lipid raft linker 1 |
RNF2 | ring finger protein 2 |
RPAP2 | RNA polymerase II associated protein 2 |
RPH3AL | rabphilin 3A-like (without C2 domains) |
SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 |
SNORA21 | small nucleolar RNA, H/ACA box 21 |
SPRYD7 | SPRY domain containing 7 |
STBD1 | starch binding domain 1 |
STK25 | serine/threonine kinase 25 |
STRN | striatin, calmodulin binding protein |
SYT17 | synaptotagmin XVII |
TAF4B | TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa |
TARS2 | threonyl-tRNA synthetase 2, mitochondrial (putative) |
TEX264 | testis expressed 264 |
TMA16 | translation machinery associated 16 homolog (S. cerevisiae) |
TMOD3 | tropomodulin 3 (ubiquitous) |
TMUB2 | transmembrane and ubiquitin-like domain containing 2 |
TNS2 | tensin 2 |
TRAIP | TRAF interacting protein |
TSPAN1 | tetraspanin 1 |
UBQLN4 | ubiquilin 4 |
ULBP2 | UL16 binding protein 2 |
USP6NL | USP6 N-terminal like |
VEGFC | vascular endothelial growth factor C |
WDR4 | WD repeat domain 4 |
XYLT2 | xylosyltransferase II |
ZFAND3 | zinc finger, AN1-type domain 3 |
ZNF668 | zinc finger protein 668 |
ZNRD1-AS1 | ZNRD1 antisense RNA 1 |