| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
| Downloads & Tools |
197 genes differentially expressed following the clozapine-1170 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACOX1 | acyl-CoA oxidase 1, palmitoyl |
| ADARB1 | adenosine deaminase, RNA-specific, B1 |
| ALS2CL | ALS2 C-terminal like |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 |
| APP | amyloid beta (A4) precursor protein |
| AREG | amphiregulin |
| ARHGAP1 | Rho GTPase activating protein 1 |
| ARL2BP | ADP-ribosylation factor-like 2 binding protein |
| ARMC6 | armadillo repeat containing 6 |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| ATP6V0A1 | ATPase, H+ transporting, lysosomal V0 subunit a1 |
| BTG2 | BTG family, member 2 |
| C1ORF56 | chromosome 1 open reading frame 56 |
| CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
| CD79B | CD79b molecule, immunoglobulin-associated beta |
| CEP290 | centrosomal protein 290kDa |
| CLCN5 | chloride channel, voltage-sensitive 5 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog |
| CTSB | cathepsin B |
| CYP1A2 | cytochrome P450, family 1, subfamily A, polypeptide 2 |
| DGKA | diacylglycerol kinase, alpha 80kDa |
| DKFZP434L187 | uncharacterized LOC26082 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
| ELL | elongation factor RNA polymerase II |
| EPHA4 | EPH receptor A4 |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) |
| ERAP2 | endoplasmic reticulum aminopeptidase 2 |
| EYA3 | EYA transcriptional coactivator and phosphatase 3 |
| FH | fumarate hydratase |
| FLI1 | Fli-1 proto-oncogene, ETS transcription factor |
| GDPD3 | glycerophosphodiester phosphodiesterase domain containing 3 |
| GLYR1 | glyoxylate reductase 1 homolog (Arabidopsis) |
| GTF3C2 | general transcription factor IIIC, polypeptide 2, beta 110kDa |
| HSDL2 | hydroxysteroid dehydrogenase like 2 |
| IKBKB | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta |
| IL1RN | interleukin 1 receptor antagonist |
| IL24 | interleukin 24 |
| INO80B | INO80 complex subunit B |
| IQSEC2 | IQ motif and Sec7 domain 2 |
| KIAA0753 | KIAA0753 |
| KIAA1109 | KIAA1109 |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LILRB4 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4 |
| MAN1C1 | mannosidase, alpha, class 1C, member 1 |
| MAP2K4 | mitogen-activated protein kinase kinase 4 |
| MAP2K5 | mitogen-activated protein kinase kinase 5 |
| MCL1 | myeloid cell leukemia 1 |
| MCOLN1 | mucolipin 1 |
| MFSD11 | major facilitator superfamily domain containing 11 |
| MSRB2 | methionine sulfoxide reductase B2 |
| MYO1B | myosin IB |
| NDST1 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 |
| NINJ2 | ninjurin 2 |
| NLK | nemo-like kinase |
| NOL3 | nucleolar protein 3 (apoptosis repressor with CARD domain) |
| NOP16 | NOP16 nucleolar protein |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 |
| OSGEPL1 | O-sialoglycoprotein endopeptidase-like 1 |
| PAM | peptidylglycine alpha-amidating monooxygenase |
| PDIA2 | protein disulfide isomerase family A, member 2 |
| POLR2D | polymerase (RNA) II (DNA directed) polypeptide D |
| PSEN1 | presenilin 1 |
| PSEN2 | presenilin 2 |
| PTAFR | platelet-activating factor receptor |
| PTBP3 | polypyrimidine tract binding protein 3 |
| PTGER4 | prostaglandin E receptor 4 (subtype EP4) |
| RDH11 | retinol dehydrogenase 11 (all-trans/9-cis/11-cis) |
| REEP4 | receptor accessory protein 4 |
| RGS14 | regulator of G-protein signaling 14 |
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 |
| RUNX1 | runt-related transcription factor 1 |
| SEC24D | SEC24 family member D |
| SH3GL1 | SH3-domain GRB2-like 1 |
| SHB | Src homology 2 domain containing adaptor protein B |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 |
| SNAPC5 | small nuclear RNA activating complex, polypeptide 5, 19kDa |
| SOAT1 | sterol O-acyltransferase 1 |
| SOX12 | SRY (sex determining region Y)-box 12 |
| SRPK3 | SRSF protein kinase 3 |
| SRSF7 | serine/arginine-rich splicing factor 7 |
| STAM2 | signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 |
| STARD3 | StAR-related lipid transfer (START) domain containing 3 |
| STK17A | serine/threonine kinase 17a |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) |
| TNNT1 | troponin T type 1 (skeletal, slow) |
| TNS1 | tensin 1 |
| TRA | T cell receptor alpha locus |
| TRAF1 | TNF receptor-associated factor 1 |
| TULP3 | tubby like protein 3 |
| UBOX5 | U-box domain containing 5 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) |
| WAPAL | wings apart-like homolog (Drosophila) |
| WDR33 | WD repeat domain 33 |
| ZBTB43 | zinc finger and BTB domain containing 43 |
| ZNF224 | zinc finger protein 224 |
| ZNF552 | zinc finger protein 552 |
| Symbol | Name |
|---|---|
| ACAD10 | acyl-CoA dehydrogenase family, member 10 |
| APOBR | apolipoprotein B receptor |
| ARFGAP1 | ADP-ribosylation factor GTPase activating protein 1 |
| ASPN | asporin |
| ATAD2B | ATPase family, AAA domain containing 2B |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 |
| ATXN2 | ataxin 2 |
| BAHD1 | bromo adjacent homology domain containing 1 |
| BAK1 | BCL2-antagonist/killer 1 |
| BRPF1 | bromodomain and PHD finger containing, 1 |
| C1ORF106 | chromosome 1 open reading frame 106 |
| C1ORF21 | chromosome 1 open reading frame 21 |
| C22ORF29 | chromosome 22 open reading frame 29 |
| C8ORF44 | chromosome 8 open reading frame 44 |
| CCDC109B | coiled-coil domain containing 109B |
| CCNJ | cyclin J |
| CD1D | CD1d molecule |
| CDKN2D | cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) |
| CEP97 | centrosomal protein 97kDa |
| CFAP44 | cilia and flagella associated protein 44 |
| CHMP1A | charged multivesicular body protein 1A |
| CLEC4E | C-type lectin domain family 4, member E |
| CLSPN | claspin |
| COG4 | component of oligomeric golgi complex 4 |
| CRIP1 | cysteine-rich protein 1 (intestinal) |
| CTNNBIP1 | catenin, beta interacting protein 1 |
| CYSLTR1 | cysteinyl leukotriene receptor 1 |
| DECR2 | 2,4-dienoyl CoA reductase 2, peroxisomal |
| DOLK | dolichol kinase |
| DYM | dymeclin |
| ERCC6L | excision repair cross-complementation group 6-like |
| FAM204A | family with sequence similarity 204, member A |
| FAM53B | family with sequence similarity 53, member B |
| FPGS | folylpolyglutamate synthase |
| GLTSCR1 | glioma tumor suppressor candidate region gene 1 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 |
| GPR22 | G protein-coupled receptor 22 |
| GPR65 | G protein-coupled receptor 65 |
| GTF2H3 | general transcription factor IIH, polypeptide 3, 34kDa |
| HDAC5 | histone deacetylase 5 |
| HELZ | helicase with zinc finger |
| HHLA3 | HERV-H LTR-associating 3 |
| IL4R | interleukin 4 receptor |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) |
| ITGAX | integrin, alpha X (complement component 3 receptor 4 subunit) |
| KIAA0556 | KIAA0556 |
| KLHL21 | kelch-like family member 21 |
| LIMD2 | LIM domain containing 2 |
| LRRC42 | leucine rich repeat containing 42 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 |
| MKL2 | MKL/myocardin-like 2 |
| MPC1 | mitochondrial pyruvate carrier 1 |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| MYL5 | myosin, light chain 5, regulatory |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| PGM1 | phosphoglucomutase 1 |
| PGPEP1 | pyroglutamyl-peptidase I |
| PLA2G15 | phospholipase A2, group XV |
| PLIN3 | perilipin 3 |
| PNOC | prepronociceptin |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha |
| RECQL4 | RecQ protein-like 4 |
| RFC4 | replication factor C (activator 1) 4, 37kDa |
| RGS19 | regulator of G-protein signaling 19 |
| SALL2 | spalt-like transcription factor 2 |
| SAMD9 | sterile alpha motif domain containing 9 |
| SCRN3 | secernin 3 |
| SETD6 | SET domain containing 6 |
| SGTA | small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha |
| SIPA1 | signal-induced proliferation-associated 1 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 |
| SMAD7 | SMAD family member 7 |
| STX17 | syntaxin 17 |
| TBX19 | T-box 19 |
| TERT | telomerase reverse transcriptase |
| THOC1 | THO complex 1 |
| TM7SF3 | transmembrane 7 superfamily member 3 |
| TMA7 | translation machinery associated 7 homolog (S. cerevisiae) |
| TMEM127 | transmembrane protein 127 |
| TNFSF13 | tumor necrosis factor (ligand) superfamily, member 13 |
| TNRC6B | trinucleotide repeat containing 6B |
| TOR3A | torsin family 3, member A |
| TPCN1 | two pore segment channel 1 |
| TRIM45 | tripartite motif containing 45 |
| TRPV2 | transient receptor potential cation channel, subfamily V, member 2 |
| TSPAN13 | tetraspanin 13 |
| TSPYL2 | TSPY-like 2 |
| TUBGCP5 | tubulin, gamma complex associated protein 5 |
| UBXN6 | UBX domain protein 6 |
| URM1 | ubiquitin related modifier 1 |
| VANGL1 | VANGL planar cell polarity protein 1 |
| VILL | villin-like |
| WT1-AS | WT1 antisense RNA |
| ZNF580 | zinc finger protein 580 |
| ZNF665 | zinc finger protein 665 |
| ZNF7 | zinc finger protein 7 |
| ZNF74 | zinc finger protein 74 |
| ZNF816 | zinc finger protein 816 |
