| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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194 genes differentially expressed following the clozapine-1229 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
| ACVR2B | activin A receptor, type IIB |
| AKAP7 | A kinase (PRKA) anchor protein 7 |
| AMDHD2 | amidohydrolase domain containing 2 |
| ARHGDIA | Rho GDP dissociation inhibitor (GDI) alpha |
| ARHGEF9 | Cdc42 guanine nucleotide exchange factor (GEF) 9 |
| ATAD5 | ATPase family, AAA domain containing 5 |
| B4GALT7 | xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7 |
| BBC3 | BCL2 binding component 3 |
| C10ORF10 | chromosome 10 open reading frame 10 |
| CA5BP1 | carbonic anhydrase VB pseudogene 1 |
| CARTPT | CART prepropeptide |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
| CEP250 | centrosomal protein 250kDa |
| CLEC4E | C-type lectin domain family 4, member E |
| CYP20A1 | cytochrome P450, family 20, subfamily A, polypeptide 1 |
| DLK2 | delta-like 2 homolog (Drosophila) |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| EDRF1 | erythroid differentiation regulatory factor 1 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 |
| EML3 | echinoderm microtubule associated protein like 3 |
| EPHA1 | EPH receptor A1 |
| FADS3 | fatty acid desaturase 3 |
| FCMR | Fc fragment of IgM receptor |
| FUT6 | fucosyltransferase 6 (alpha (1,3) fucosyltransferase) |
| GHRHR | growth hormone releasing hormone receptor |
| GJA4 | gap junction protein, alpha 4, 37kDa |
| GNAZ | guanine nucleotide binding protein (G protein), alpha z polypeptide |
| GRTP1 | growth hormone regulated TBC protein 1 |
| GSK3A | glycogen synthase kinase 3 alpha |
| HPS1 | Hermansky-Pudlak syndrome 1 |
| KAZALD1 | Kazal-type serine peptidase inhibitor domain 1 |
| KIR2DL5A | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A |
| KRT24 | keratin 24, type I |
| KYNU | kynureninase |
| LAMA4 | laminin, alpha 4 |
| LPCAT3 | lysophosphatidylcholine acyltransferase 3 |
| LRFN3 | leucine rich repeat and fibronectin type III domain containing 3 |
| LYZ | lysozyme |
| MDFI | MyoD family inhibitor |
| MEFV | Mediterranean fever |
| METTL5 | methyltransferase like 5 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) |
| NDE1 | nudE neurodevelopment protein 1 |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NOS1 | nitric oxide synthase 1 (neuronal) |
| NPAS2 | neuronal PAS domain protein 2 |
| PAFAH2 | platelet-activating factor acetylhydrolase 2, 40kDa |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PDIA2 | protein disulfide isomerase family A, member 2 |
| PER3 | period circadian clock 3 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLCH1 | phospholipase C, eta 1 |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PLEKHO1 | pleckstrin homology domain containing, family O member 1 |
| PMS2P3 | postmeiotic segregation increased 2 pseudogene 3 |
| PPP1R7 | protein phosphatase 1, regulatory subunit 7 |
| PTAFR | platelet-activating factor receptor |
| PTPN18 | protein tyrosine phosphatase, non-receptor type 18 (brain-derived) |
| RAB11FIP3 | RAB11 family interacting protein 3 (class II) |
| RGS4 | regulator of G-protein signaling 4 |
| RHOBTB2 | Rho-related BTB domain containing 2 |
| RPLP2 | ribosomal protein, large, P2 |
| RTEL1 | regulator of telomere elongation helicase 1 |
| SFTPB | surfactant protein B |
| SHMT1 | serine hydroxymethyltransferase 1 (soluble) |
| SIX1 | SIX homeobox 1 |
| SLC12A4 | solute carrier family 12 (potassium/chloride transporter), member 4 |
| SLC4A3 | solute carrier family 4 (anion exchanger), member 3 |
| SLN | sarcolipin |
| SMARCA2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 |
| SMG5 | SMG5 nonsense mediated mRNA decay factor |
| SOD3 | superoxide dismutase 3, extracellular |
| SPTB | spectrin, beta, erythrocytic |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 |
| SSX1 | synovial sarcoma, X breakpoint 1 |
| SUPT20H | suppressor of Ty 20 homolog (S. cerevisiae) |
| SYNGR4 | synaptogyrin 4 |
| TADA2A | transcriptional adaptor 2A |
| TBL2 | transducin (beta)-like 2 |
| TJAP1 | tight junction associated protein 1 (peripheral) |
| TLE2 | transducin-like enhancer of split 2 |
| TMEM209 | transmembrane protein 209 |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
| TP53I11 | tumor protein p53 inducible protein 11 |
| TRABD | TraB domain containing |
| TRIM25 | tripartite motif containing 25 |
| TRPM4 | transient receptor potential cation channel, subfamily M, member 4 |
| USB1 | U6 snRNA biogenesis 1 |
| WIPI2 | WD repeat domain, phosphoinositide interacting 2 |
| ZBTB6 | zinc finger and BTB domain containing 6 |
| ZNF197 | zinc finger protein 197 |
| ZNF606 | zinc finger protein 606 |
| ZNF74 | zinc finger protein 74 |
| ZNF862 | zinc finger protein 862 |
| Symbol | Name |
|---|---|
| ABHD8 | abhydrolase domain containing 8 |
| ACAD10 | acyl-CoA dehydrogenase family, member 10 |
| ACBD4 | acyl-CoA binding domain containing 4 |
| AEN | apoptosis enhancing nuclease |
| ALPK1 | alpha-kinase 1 |
| ANKEF1 | ankyrin repeat and EF-hand domain containing 1 |
| APLP1 | amyloid beta (A4) precursor-like protein 1 |
| ARRB2 | arrestin, beta 2 |
| ARSJ | arylsulfatase family, member J |
| ASB7 | ankyrin repeat and SOCS box containing 7 |
| BAG4 | BCL2-associated athanogene 4 |
| BCL9 | B-cell CLL/lymphoma 9 |
| BCOR | BCL6 corepressor |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 |
| BRIX1 | BRX1, biogenesis of ribosomes |
| C4ORF19 | chromosome 4 open reading frame 19 |
| CCBL1 | cysteine conjugate-beta lyase, cytoplasmic |
| CCP110 | centriolar coiled coil protein 110kDa |
| CDC37L1 | cell division cycle 37-like 1 |
| CHML | choroideremia-like (Rab escort protein 2) |
| CLCN5 | chloride channel, voltage-sensitive 5 |
| CNTNAP3B | contactin associated protein-like 3B |
| CTSF | cathepsin F |
| DCAF13 | DDB1 and CUL4 associated factor 13 |
| DEPTOR | DEP domain containing MTOR-interacting protein |
| DLEU2 | deleted in lymphocytic leukemia 2 (non-protein coding) |
| DMTN | dematin actin binding protein |
| EML4 | echinoderm microtubule associated protein like 4 |
| EYA4 | EYA transcriptional coactivator and phosphatase 4 |
| FBXL6 | F-box and leucine-rich repeat protein 6 |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FUZ | fuzzy planar cell polarity protein |
| GID4 | GID complex subunit 4 |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GRAMD1C | GRAM domain containing 1C |
| HDAC5 | histone deacetylase 5 |
| HSPA4L | heat shock 70kDa protein 4-like |
| IKZF5 | IKAROS family zinc finger 5 (Pegasus) |
| IREB2 | iron-responsive element binding protein 2 |
| KDM5C | lysine (K)-specific demethylase 5C |
| LPAR3 | lysophosphatidic acid receptor 3 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 |
| LYPD1 | LY6/PLAUR domain containing 1 |
| MAFG | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G |
| MAGEA6 | melanoma antigen family A6 |
| MAGEH1 | melanoma antigen family H1 |
| MAP6D1 | MAP6 domain containing 1 |
| METTL8 | methyltransferase like 8 |
| MFSD6 | major facilitator superfamily domain containing 6 |
| MRPL44 | mitochondrial ribosomal protein L44 |
| MUM1 | melanoma associated antigen (mutated) 1 |
| MYLIP | myosin regulatory light chain interacting protein |
| NDUFS1 | NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) |
| NOL12 | nucleolar protein 12 |
| NOTCH1 | notch 1 |
| NRSN2 | neurensin 2 |
| NYNRIN | NYN domain and retroviral integrase containing |
| OSMR | oncostatin M receptor |
| PARP3 | poly (ADP-ribose) polymerase family, member 3 |
| PCYT2 | phosphate cytidylyltransferase 2, ethanolamine |
| PEX26 | peroxisomal biogenesis factor 26 |
| PGM1 | phosphoglucomutase 1 |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta |
| PLCG2 | phospholipase C, gamma 2 (phosphatidylinositol-specific) |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor |
| PRR14L | proline rich 14-like |
| PSKH1 | protein serine kinase H1 |
| PTGFR | prostaglandin F receptor (FP) |
| RARS | arginyl-tRNA synthetase |
| RBBP5 | retinoblastoma binding protein 5 |
| SCYL2 | SCY1-like 2 (S. cerevisiae) |
| SEC61A2 | Sec61 alpha 2 subunit (S. cerevisiae) |
| SLC19A2 | solute carrier family 19 (thiamine transporter), member 2 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 |
| SNPH | syntaphilin |
| SPATA7 | spermatogenesis associated 7 |
| SPEG | SPEG complex locus |
| SPIDR | scaffolding protein involved in DNA repair |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) |
| SYTL2 | synaptotagmin-like 2 |
| TGS1 | trimethylguanosine synthase 1 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 |
| TMEM104 | transmembrane protein 104 |
| TMEM177 | transmembrane protein 177 |
| TRAIP | TRAF interacting protein |
| TSPAN8 | tetraspanin 8 |
| VCPIP1 | valosin containing protein (p97)/p47 complex interacting protein 1 |
| ZHX2 | zinc fingers and homeoboxes 2 |
| ZMYM3 | zinc finger, MYM-type 3 |
| ZNF177 | zinc finger protein 177 |
| ZNF230 | zinc finger protein 230 |
| ZNF253 | zinc finger protein 253 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF574 | zinc finger protein 574 |
| ZNF623 | zinc finger protein 623 |
| ZNF667 | zinc finger protein 667 |
| ZSCAN5A | zinc finger and SCAN domain containing 5A |
