| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the clozapine-1654 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAM17 | ADAM metallopeptidase domain 17 |
| ADPRM | ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent |
| AK1 | adenylate kinase 1 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B |
| BTRC | beta-transducin repeat containing E3 ubiquitin protein ligase |
| C9ORF156 | chromosome 9 open reading frame 156 |
| CCDC121 | coiled-coil domain containing 121 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) |
| CDK3 | cyclin-dependent kinase 3 |
| CHKB | choline kinase beta |
| COPZ2 | coatomer protein complex, subunit zeta 2 |
| DSCR3 | Down syndrome critical region 3 |
| EDRF1 | erythroid differentiation regulatory factor 1 |
| EGFL7 | EGF-like-domain, multiple 7 |
| ENPEP | glutamyl aminopeptidase (aminopeptidase A) |
| ERAP1 | endoplasmic reticulum aminopeptidase 1 |
| EXOC7 | exocyst complex component 7 |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FAM174B | family with sequence similarity 174, member B |
| FAM46C | family with sequence similarity 46, member C |
| FILIP1L | filamin A interacting protein 1-like |
| FSCN1 | fascin actin-bundling protein 1 |
| GAMT | guanidinoacetate N-methyltransferase |
| GNL3L | guanine nucleotide binding protein-like 3 (nucleolar)-like |
| GPR1 | G protein-coupled receptor 1 |
| GSK3A | glycogen synthase kinase 3 alpha |
| GSPT1 | G1 to S phase transition 1 |
| HECW1 | HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 |
| HIP1 | huntingtin interacting protein 1 |
| HIST1H2AI | histone cluster 1, H2ai |
| HSDL2 | hydroxysteroid dehydrogenase like 2 |
| ICOSLG | inducible T-cell co-stimulator ligand |
| IFT38 | intraflagellar transport 38 |
| IL11 | interleukin 11 |
| IL4R | interleukin 4 receptor |
| INPP4A | inositol polyphosphate-4-phosphatase, type I, 107kDa |
| KAT6A | K(lysine) acetyltransferase 6A |
| KAZALD1 | Kazal-type serine peptidase inhibitor domain 1 |
| KIAA0040 | KIAA0040 |
| KRI1 | KRI1 homolog (S. cerevisiae) |
| LEPR | leptin receptor |
| LINC00339 | long intergenic non-protein coding RNA 339 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) |
| LUZP1 | leucine zipper protein 1 |
| LUZP4 | leucine zipper protein 4 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 |
| MARK4 | MAP/microtubule affinity-regulating kinase 4 |
| MEIS2 | Meis homeobox 2 |
| METTL5 | methyltransferase like 5 |
| MFHAS1 | malignant fibrous histiocytoma amplified sequence 1 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 |
| MMP2 | matrix metallopeptidase 2 |
| MSL3 | male-specific lethal 3 homolog (Drosophila) |
| NAB2 | NGFI-A binding protein 2 (EGR1 binding protein 2) |
| NEK1 | NIMA-related kinase 1 |
| NEK3 | NIMA-related kinase 3 |
| NOX1 | NADPH oxidase 1 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| NYNRIN | NYN domain and retroviral integrase containing |
| PCDHGB5 | protocadherin gamma subfamily B, 5 |
| PEX3 | peroxisomal biogenesis factor 3 |
| PIDD1 | p53-induced death domain protein 1 |
| PIM1 | Pim-1 proto-oncogene, serine/threonine kinase |
| PLD2 | phospholipase D2 |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 |
| PRR4 | proline rich 4 (lacrimal) |
| RAB2A | RAB2A, member RAS oncogene family |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RAD51B | RAD51 paralog B |
| RAP2B | RAP2B, member of RAS oncogene family |
| RBM19 | RNA binding motif protein 19 |
| RNF39 | ring finger protein 39 |
| RPL35A | ribosomal protein L35a |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| SEMA4G | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 |
| SLC27A5 | solute carrier family 27 (fatty acid transporter), member 5 |
| SMARCA2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 |
| SRPR | signal recognition particle receptor (docking protein) |
| SRSF8 | serine/arginine-rich splicing factor 8 |
| STRN3 | striatin, calmodulin binding protein 3 |
| TFG | TRK-fused gene |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 |
| TK2 | thymidine kinase 2, mitochondrial |
| TLR5 | toll-like receptor 5 |
| TNFAIP1 | tumor necrosis factor, alpha-induced protein 1 (endothelial) |
| TRIM25 | tripartite motif containing 25 |
| TSPAN9 | tetraspanin 9 |
| TTBK2 | tau tubulin kinase 2 |
| TWF1 | twinfilin actin binding protein 1 |
| VGF | VGF nerve growth factor inducible |
| XK | X-linked Kx blood group |
| ZCCHC24 | zinc finger, CCHC domain containing 24 |
| ZER1 | zyg-11 related, cell cycle regulator |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 |
| ZNF75D | zinc finger protein 75D |
| ZNF862 | zinc finger protein 862 |
| Symbol | Name |
|---|---|
| ABLIM3 | actin binding LIM protein family, member 3 |
| ACAD10 | acyl-CoA dehydrogenase family, member 10 |
| ACTR3B | ARP3 actin-related protein 3 homolog B (yeast) |
| ACVR2A | activin A receptor, type IIA |
| ADCY6 | adenylate cyclase 6 |
| ADGRE5 | adhesion G protein-coupled receptor E5 |
| APOD | apolipoprotein D |
| BATF | basic leucine zipper transcription factor, ATF-like |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| BCL2L2 | BCL2-like 2 |
| C11ORF80 | chromosome 11 open reading frame 80 |
| C1ORF56 | chromosome 1 open reading frame 56 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CAMTA2 | calmodulin binding transcription activator 2 |
| CASZ1 | castor zinc finger 1 |
| CCNO | cyclin O |
| CCNT1 | cyclin T1 |
| CCP110 | centriolar coiled coil protein 110kDa |
| CCT6B | chaperonin containing TCP1, subunit 6B (zeta 2) |
| CD302 | CD302 molecule |
| CDC73 | cell division cycle 73 |
| CDKL3 | cyclin-dependent kinase-like 3 |
| CGA | glycoprotein hormones, alpha polypeptide |
| CHPF | chondroitin polymerizing factor |
| CLDN15 | claudin 15 |
| CLEC16A | C-type lectin domain family 16, member A |
| COG4 | component of oligomeric golgi complex 4 |
| CORO1A | coronin, actin binding protein, 1A |
| CORO2A | coronin, actin binding protein, 2A |
| CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 |
| CTSK | cathepsin K |
| DENND4A | DENN/MADD domain containing 4A |
| DFFB | DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) |
| EFHD2 | EF-hand domain family, member D2 |
| EFNA3 | ephrin-A3 |
| ELOVL4 | ELOVL fatty acid elongase 4 |
| FBXO22 | F-box protein 22 |
| FLJ22184 | |
| FOXRED2 | FAD-dependent oxidoreductase domain containing 2 |
| FUT1 | fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GTF3C5 | general transcription factor IIIC, polypeptide 5, 63kDa |
| HGSNAT | heparan-alpha-glucosaminide N-acetyltransferase |
| HIST1H2AM | histone cluster 1, H2am |
| HMGCL | 3-hydroxymethyl-3-methylglutaryl-CoA lyase |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| IL15RA | interleukin 15 receptor, alpha |
| KCNF1 | potassium channel, voltage gated modifier subfamily F, member 1 |
| KCTD20 | potassium channel tetramerization domain containing 20 |
| LNPEP | leucyl/cystinyl aminopeptidase |
| LOC730101 | uncharacterized LOC730101 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MECR | mitochondrial trans-2-enoyl-CoA reductase |
| METTL16 | methyltransferase like 16 |
| MITF | microphthalmia-associated transcription factor |
| MUM1 | melanoma associated antigen (mutated) 1 |
| MYO1D | myosin ID |
| NABP2 | nucleic acid binding protein 2 |
| NCAM2 | neural cell adhesion molecule 2 |
| NFE2L3 | nuclear factor, erythroid 2-like 3 |
| NKAIN1 | Na+/K+ transporting ATPase interacting 1 |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| NRGN | neurogranin (protein kinase C substrate, RC3) |
| OTUD3 | OTU deubiquitinase 3 |
| PARG | poly (ADP-ribose) glycohydrolase |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLD3 | phospholipase D family, member 3 |
| PLEKHO1 | pleckstrin homology domain containing, family O member 1 |
| RABL3 | RAB, member of RAS oncogene family-like 3 |
| RECQL4 | RecQ protein-like 4 |
| RFTN1 | raftlin, lipid raft linker 1 |
| RNPEPL1 | arginyl aminopeptidase (aminopeptidase B)-like 1 |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SH2D4A | SH2 domain containing 4A |
| SIDT1 | SID1 transmembrane family, member 1 |
| SKA1 | spindle and kinetochore associated complex subunit 1 |
| SLC16A6 | solute carrier family 16, member 6 |
| SLC25A28 | solute carrier family 25 (mitochondrial iron transporter), member 28 |
| SLC2A4RG | SLC2A4 regulator |
| SLC2A8 | solute carrier family 2 (facilitated glucose transporter), member 8 |
| SMARCAL1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 |
| SNAPC2 | small nuclear RNA activating complex, polypeptide 2, 45kDa |
| SPAG4 | sperm associated antigen 4 |
| SPATA2L | spermatogenesis associated 2-like |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 |
| TCTN2 | tectonic family member 2 |
| THBS3 | thrombospondin 3 |
| TMEM177 | transmembrane protein 177 |
| TPRA1 | transmembrane protein, adipocyte asscociated 1 |
| TTC23 | tetratricopeptide repeat domain 23 |
| TUBG2 | tubulin, gamma 2 |
| UBQLN4 | ubiquilin 4 |
| ZAK | sterile alpha motif and leucine zipper containing kinase AZK |
| ZBTB48 | zinc finger and BTB domain containing 48 |
| ZC3H3 | zinc finger CCCH-type containing 3 |
| ZNF324 | zinc finger protein 324 |
| ZNF787 | zinc finger protein 787 |
| ZNHIT2 | zinc finger, HIT-type containing 2 |
