| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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196 genes differentially expressed following the clozapine-2644 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A1CF | APOBEC1 complementation factor |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
| ACAA2 | acetyl-CoA acyltransferase 2 |
| AGFG2 | ArfGAP with FG repeats 2 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 |
| ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B |
| BEND5 | BEN domain containing 5 |
| BIN1 | bridging integrator 1 |
| C10ORF95 | chromosome 10 open reading frame 95 |
| C1QL1 | complement component 1, q subcomponent-like 1 |
| C22ORF46 | chromosome 22 open reading frame 46 |
| CASP5 | caspase 5, apoptosis-related cysteine peptidase |
| CD300A | CD300a molecule |
| CD6 | CD6 molecule |
| CDHR2 | cadherin-related family member 2 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 |
| COL1A1 | collagen, type I, alpha 1 |
| COL4A1 | collagen, type IV, alpha 1 |
| CPNE7 | copine VII |
| CTDSPL | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like |
| CYP4F11 | cytochrome P450, family 4, subfamily F, polypeptide 11 |
| CYTH4 | cytohesin 4 |
| DMTN | dematin actin binding protein |
| DOK2 | docking protein 2, 56kDa |
| DUSP1 | dual specificity phosphatase 1 |
| ELL | elongation factor RNA polymerase II |
| ELL2 | elongation factor, RNA polymerase II, 2 |
| ELOVL5 | ELOVL fatty acid elongase 5 |
| FAM155A | family with sequence similarity 155, member A |
| FAM184A | family with sequence similarity 184, member A |
| FGF6 | fibroblast growth factor 6 |
| FH | fumarate hydratase |
| FLOT2 | flotillin 2 |
| FOXN2 | forkhead box N2 |
| FRMPD1 | FERM and PDZ domain containing 1 |
| GABRR2 | gamma-aminobutyric acid (GABA) A receptor, rho 2 |
| GNA14 | guanine nucleotide binding protein (G protein), alpha 14 |
| HES2 | hes family bHLH transcription factor 2 |
| HR | hair growth associated |
| IGLJ3 | immunoglobulin lambda joining 3 |
| INHBC | inhibin, beta C |
| INPP5B | inositol polyphosphate-5-phosphatase, 75kDa |
| IQSEC2 | IQ motif and Sec7 domain 2 |
| JUN | jun proto-oncogene |
| KLK7 | kallikrein-related peptidase 7 |
| KRT83 | keratin 83, type II |
| LAMA4 | laminin, alpha 4 |
| LLGL1 | lethal giant larvae homolog 1 (Drosophila) |
| LRRC48 | leucine rich repeat containing 48 |
| LSM4 | LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MARK4 | MAP/microtubule affinity-regulating kinase 4 |
| METTL7A | methyltransferase like 7A |
| MOCS1 | molybdenum cofactor synthesis 1 |
| NEB | nebulin |
| NOL12 | nucleolar protein 12 |
| NPTX1 | neuronal pentraxin I |
| NR2F6 | nuclear receptor subfamily 2, group F, member 6 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| ONECUT2 | one cut homeobox 2 |
| PARVB | parvin, beta |
| PAX8 | paired box 8 |
| PHF7 | PHD finger protein 7 |
| PIN1P1 | peptidylprolyl cis/trans isomerase, NIMA-interacting 1 pseudogene 1 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| POFUT1 | protein O-fucosyltransferase 1 |
| PPARD | peroxisome proliferator-activated receptor delta |
| PRB3 | proline-rich protein BstNI subfamily 3 |
| PRKCA | protein kinase C, alpha |
| PRKCE | protein kinase C, epsilon |
| PTGS1 | prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) |
| RABGAP1L | RAB GTPase activating protein 1-like |
| RNF43 | ring finger protein 43 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| RUNX1 | runt-related transcription factor 1 |
| SENP7 | SUMO1/sentrin specific peptidase 7 |
| SH2D1A | SH2 domain containing 1A |
| SLC11A1 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 |
| SLIT1 | slit homolog 1 (Drosophila) |
| SPAG8 | sperm associated antigen 8 |
| SPOCK2 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 |
| STMN3 | stathmin-like 3 |
| TAS2R9 | taste receptor, type 2, member 9 |
| TDRKH | tudor and KH domain containing |
| TGFB1 | transforming growth factor, beta 1 |
| TMCC2 | transmembrane and coiled-coil domain family 2 |
| TRAC | T cell receptor alpha constant |
| UBXN1 | UBX domain protein 1 |
| UGT2B15 | UDP glucuronosyltransferase 2 family, polypeptide B15 |
| VWA5A | von Willebrand factor A domain containing 5A |
| XYLB | xylulokinase homolog (H. influenzae) |
| ZFP37 | ZFP37 zinc finger protein |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF771 | zinc finger protein 771 |
| Symbol | Name |
|---|---|
| ADCY6 | adenylate cyclase 6 |
| ADORA2B | adenosine A2b receptor |
| ANKFY1 | ankyrin repeat and FYVE domain containing 1 |
| ANKRD40 | ankyrin repeat domain 40 |
| ARHGDIG | Rho GDP dissociation inhibitor (GDI) gamma |
| ARRB1 | arrestin, beta 1 |
| ATAD3A | ATPase family, AAA domain containing 3A |
| AXIN1 | axin 1 |
| B4GALT2 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 |
| BTBD2 | BTB (POZ) domain containing 2 |
| C11ORF30 | chromosome 11 open reading frame 30 |
| CBX7 | chromobox homolog 7 |
| CCDC85C | coiled-coil domain containing 85C |
| CD79B | CD79b molecule, immunoglobulin-associated beta |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHKB | choline kinase beta |
| CLASP1 | cytoplasmic linker associated protein 1 |
| CLCN5 | chloride channel, voltage-sensitive 5 |
| CLDN15 | claudin 15 |
| CLK1 | CDC-like kinase 1 |
| CTNNBIP1 | catenin, beta interacting protein 1 |
| CXORF56 | chromosome X open reading frame 56 |
| DNA2 | DNA replication helicase/nuclease 2 |
| EFNA3 | ephrin-A3 |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 |
| FBRS | fibrosin |
| FILIP1L | filamin A interacting protein 1-like |
| GID4 | GID complex subunit 4 |
| GLCE | glucuronic acid epimerase |
| GMEB1 | glucocorticoid modulatory element binding protein 1 |
| GRPR | gastrin-releasing peptide receptor |
| HOOK1 | hook microtubule-tethering protein 1 |
| HTR1E | 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled |
| KIF13B | kinesin family member 13B |
| KIFAP3 | kinesin-associated protein 3 |
| KLF3 | Kruppel-like factor 3 (basic) |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein |
| LIG4 | ligase IV, DNA, ATP-dependent |
| LINC00115 | long intergenic non-protein coding RNA 115 |
| LINC00339 | long intergenic non-protein coding RNA 339 |
| LRRC20 | leucine rich repeat containing 20 |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C |
| LYPD1 | LY6/PLAUR domain containing 1 |
| MANEA | mannosidase, endo-alpha |
| MAP1S | microtubule-associated protein 1S |
| MC1R | melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) |
| MED24 | mediator complex subunit 24 |
| MEIS1 | Meis homeobox 1 |
| MTRF1 | mitochondrial translational release factor 1 |
| MVD | mevalonate (diphospho) decarboxylase |
| NKX3-2 | NK3 homeobox 2 |
| NPFFR1 | neuropeptide FF receptor 1 |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| NUBPL | nucleotide binding protein-like |
| OLFML2A | olfactomedin-like 2A |
| PADI2 | peptidyl arginine deiminase, type II |
| PEX26 | peroxisomal biogenesis factor 26 |
| PHEX | phosphate regulating endopeptidase homolog, X-linked |
| PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) |
| PIP5K1C | phosphatidylinositol-4-phosphate 5-kinase, type I, gamma |
| PITPNM1 | phosphatidylinositol transfer protein, membrane-associated 1 |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| PMCH | pro-melanin-concentrating hormone |
| POLE | polymerase (DNA directed), epsilon, catalytic subunit |
| POLL | polymerase (DNA directed), lambda |
| PPIP5K1 | diphosphoinositol pentakisphosphate kinase 1 |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| RARS | arginyl-tRNA synthetase |
| RNASEL | ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) |
| RNF121 | ring finger protein 121 |
| RNF141 | ring finger protein 141 |
| RPAIN | RPA interacting protein |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 |
| SLC12A9 | solute carrier family 12, member 9 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 |
| SLC4A8 | solute carrier family 4, sodium bicarbonate cotransporter, member 8 |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
| SPG11 | spastic paraplegia 11 (autosomal recessive) |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| SSFA2 | sperm specific antigen 2 |
| STX1A | syntaxin 1A (brain) |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TCTN2 | tectonic family member 2 |
| TFB1M | transcription factor B1, mitochondrial |
| TICAM1 | toll-like receptor adaptor molecule 1 |
| TMEM180 | transmembrane protein 180 |
| TMEM62 | transmembrane protein 62 |
| TYW1 | tRNA-yW synthesizing protein 1 homolog (S. cerevisiae) |
| UBXN8 | UBX domain protein 8 |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZBTB25 | zinc finger and BTB domain containing 25 |
| ZMAT5 | zinc finger, matrin-type 5 |
| ZNF329 | zinc finger protein 329 |
| ZNF573 | zinc finger protein 573 |
| ZNF74 | zinc finger protein 74 |
| ZNF770 | zinc finger protein 770 |
| ZNRD1-AS1 | ZNRD1 antisense RNA 1 |