| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
| Downloads & Tools |
197 genes differentially expressed following the clozapine-4453 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACO2 | aconitase 2, mitochondrial |
| ADAM28 | ADAM metallopeptidase domain 28 |
| ADGRL3 | adhesion G protein-coupled receptor L3 |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide |
| AHSG | alpha-2-HS-glycoprotein |
| ANGPTL2 | angiopoietin-like 2 |
| ARSA | arylsulfatase A |
| ARVCF | armadillo repeat gene deleted in velocardiofacial syndrome |
| ATHL1 | ATH1, acid trehalase-like 1 (yeast) |
| ATN1 | atrophin 1 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A |
| BHLHB9 | basic helix-loop-helix domain containing, class B, 9 |
| CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
| CADM3 | cell adhesion molecule 3 |
| CALB2 | calbindin 2 |
| CAMKV | CaM kinase-like vesicle-associated |
| CCL27 | chemokine (C-C motif) ligand 27 |
| CD52 | CD52 molecule |
| CD6 | CD6 molecule |
| CELSR3 | cadherin, EGF LAG seven-pass G-type receptor 3 |
| CLCA1 | chloride channel accessory 1 |
| CLCN7 | chloride channel, voltage-sensitive 7 |
| CMAHP | cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene |
| CTLA4 | cytotoxic T-lymphocyte-associated protein 4 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| CYP2J2 | cytochrome P450, family 2, subfamily J, polypeptide 2 |
| DDR1-AS1 | DDR1 antisense RNA 1 (head to head) |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked |
| DGKE | diacylglycerol kinase, epsilon 64kDa |
| DOK2 | docking protein 2, 56kDa |
| EDN1 | endothelin 1 |
| EIF3F | eukaryotic translation initiation factor 3, subunit F |
| ESR1 | estrogen receptor 1 |
| FAIM2 | Fas apoptotic inhibitory molecule 2 |
| FCAR | Fc fragment of IgA receptor |
| FGF6 | fibroblast growth factor 6 |
| FUT7 | fucosyltransferase 7 (alpha (1,3) fucosyltransferase) |
| GABRG3 | gamma-aminobutyric acid (GABA) A receptor, gamma 3 |
| GAD2 | glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GRM8 | glutamate receptor, metabotropic 8 |
| GSTTP1 | glutathione S-transferase theta pseudogene 1 |
| HAMP | hepcidin antimicrobial peptide |
| HAO2 | hydroxyacid oxidase 2 (long chain) |
| HGF | hepatocyte growth factor (hepapoietin A; scatter factor) |
| HIST1H3F | histone cluster 1, H3f |
| HNF4A | hepatocyte nuclear factor 4, alpha |
| HPCA | hippocalcin |
| IL12B | interleukin 12B |
| IRF4 | interferon regulatory factor 4 |
| ITGB8 | integrin, beta 8 |
| KHK | ketohexokinase (fructokinase) |
| KLF13 | Kruppel-like factor 13 |
| KLK12 | kallikrein-related peptidase 12 |
| LAX1 | lymphocyte transmembrane adaptor 1 |
| LCP2 | lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) |
| LILRB2 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 |
| LRP4 | low density lipoprotein receptor-related protein 4 |
| MAP2K7 | mitogen-activated protein kinase kinase 7 |
| MAP7D3 | MAP7 domain containing 3 |
| MED25 | mediator complex subunit 25 |
| MRC2 | mannose receptor, C type 2 |
| MS4A12 | membrane-spanning 4-domains, subfamily A, member 12 |
| MSLN | mesothelin |
| NCAPH2 | non-SMC condensin II complex, subunit H2 |
| NPY6R | neuropeptide Y receptor Y6 (pseudogene) |
| NRG1 | neuregulin 1 |
| ONECUT2 | one cut homeobox 2 |
| OR10J1 | olfactory receptor, family 10, subfamily J, member 1 |
| PAGE4 | P antigen family, member 4 (prostate associated) |
| PAX5 | paired box 5 |
| PCDH12 | protocadherin 12 |
| PGLYRP4 | peptidoglycan recognition protein 4 |
| PHOX2A | paired-like homeobox 2a |
| PIAS2 | protein inhibitor of activated STAT, 2 |
| PIGR | polymeric immunoglobulin receptor |
| PPP2R2B | protein phosphatase 2, regulatory subunit B, beta |
| PTPRCAP | protein tyrosine phosphatase, receptor type, C-associated protein |
| PYY | peptide YY |
| RGCC | regulator of cell cycle |
| RNASE2 | ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) |
| RNF208 | ring finger protein 208 |
| RUNX1T1 | runt-related transcription factor 1; translocated to, 1 (cyclin D-related) |
| RUNX3 | runt-related transcription factor 3 |
| SALL1 | spalt-like transcription factor 1 |
| SCNN1D | sodium channel, non voltage gated 1 delta subunit |
| SLC11A1 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 |
| SLC15A1 | solute carrier family 15 (oligopeptide transporter), member 1 |
| SLC17A2 | solute carrier family 17, member 2 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 |
| SPAG6 | sperm associated antigen 6 |
| SPAG8 | sperm associated antigen 8 |
| SULF1 | sulfatase 1 |
| SVIL | supervillin |
| TEF | thyrotrophic embryonic factor |
| TOX | thymocyte selection-associated high mobility group box |
| UGT2B17 | UDP glucuronosyltransferase 2 family, polypeptide B17 |
| UNC93A | unc-93 homolog A (C. elegans) |
| WHSC1L1 | Wolf-Hirschhorn syndrome candidate 1-like 1 |
| ZNF440 | zinc finger protein 440 |
| Symbol | Name |
|---|---|
| ABHD4 | abhydrolase domain containing 4 |
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| ADGRB2 | adhesion G protein-coupled receptor B2 |
| ALDH3B1 | aldehyde dehydrogenase 3 family, member B1 |
| ALPK1 | alpha-kinase 1 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) |
| ATG16L1 | autophagy related 16-like 1 (S. cerevisiae) |
| BEX1 | brain expressed, X-linked 1 |
| BMP4 | bone morphogenetic protein 4 |
| BNC1 | basonuclin 1 |
| C14ORF93 | chromosome 14 open reading frame 93 |
| C17ORF53 | chromosome 17 open reading frame 53 |
| C17ORF80 | chromosome 17 open reading frame 80 |
| C1QTNF3 | C1q and tumor necrosis factor related protein 3 |
| C1R | complement component 1, r subcomponent |
| C5 | complement component 5 |
| CAMKMT | calmodulin-lysine N-methyltransferase |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CCNO | cyclin O |
| CD70 | CD70 molecule |
| CFAP45 | cilia and flagella associated protein 45 |
| CHMP1A | charged multivesicular body protein 1A |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 |
| CHST12 | carbohydrate (chondroitin 4) sulfotransferase 12 |
| CIDEC | cell death-inducing DFFA-like effector c |
| CLDN11 | claudin 11 |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
| CLUHP3 | clustered mitochondria (cluA/CLU1) homolog pseudogene 3 |
| CNTLN | centlein, centrosomal protein |
| COBL | cordon-bleu WH2 repeat protein |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| DBNDD1 | dysbindin (dystrobrevin binding protein 1) domain containing 1 |
| DHX38 | DEAH (Asp-Glu-Ala-His) box polypeptide 38 |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| EML4 | echinoderm microtubule associated protein like 4 |
| ERCC4 | excision repair cross-complementation group 4 |
| ERF | Ets2 repressor factor |
| GLDC | glycine dehydrogenase (decarboxylating) |
| GPR176 | G protein-coupled receptor 176 |
| GPRIN2 | G protein regulated inducer of neurite outgrowth 2 |
| GRAMD1C | GRAM domain containing 1C |
| GUCY1B2 | guanylate cyclase 1, soluble, beta 2 (pseudogene) |
| HDAC11 | histone deacetylase 11 |
| HDHD3 | haloacid dehalogenase-like hydrolase domain containing 3 |
| HYMAI | hydatidiform mole associated and imprinted (non-protein coding) |
| IFI30 | interferon, gamma-inducible protein 30 |
| IL12RB1 | interleukin 12 receptor, beta 1 |
| IL33 | interleukin 33 |
| KIAA1107 | KIAA1107 |
| LINC00597 | long intergenic non-protein coding RNA 597 |
| LMTK1 | lemur tail kinase 1 |
| LRP3 | low density lipoprotein receptor-related protein 3 |
| LRRC37A4P | leucine rich repeat containing 37, member A4, pseudogene |
| MCRS1 | microspherule protein 1 |
| MOXD1 | monooxygenase, DBH-like 1 |
| MTA2 | metastasis associated 1 family, member 2 |
| MUM1 | melanoma associated antigen (mutated) 1 |
| MXD3 | MAX dimerization protein 3 |
| NUS1P3 | nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3 |
| OSMR | oncostatin M receptor |
| PAK3 | p21 protein (Cdc42/Rac)-activated kinase 3 |
| PAX9 | paired box 9 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase |
| PER3 | period circadian clock 3 |
| PHEX | phosphate regulating endopeptidase homolog, X-linked |
| PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) |
| PLA1A | phospholipase A1 member A |
| POLL | polymerase (DNA directed), lambda |
| POLM | polymerase (DNA directed), mu |
| PORCN | porcupine homolog (Drosophila) |
| PSAT1 | phosphoserine aminotransferase 1 |
| QSER1 | glutamine and serine rich 1 |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RNF25 | ring finger protein 25 |
| S100A3 | S100 calcium binding protein A3 |
| SCMH1 | sex comb on midleg homolog 1 (Drosophila) |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SLC43A1 | solute carrier family 43 (amino acid system L transporter), member 1 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| SUGCT | succinyl-CoA:glutarate-CoA transferase |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TCTN1 | tectonic family member 1 |
| THOP1 | thimet oligopeptidase 1 |
| THRAP3 | thyroid hormone receptor associated protein 3 |
| TMEM209 | transmembrane protein 209 |
| TRIM25 | tripartite motif containing 25 |
| TRIM45 | tripartite motif containing 45 |
| TUBA3C | tubulin, alpha 3c |
| TUBGCP5 | tubulin, gamma complex associated protein 5 |
| XPNPEP3 | X-prolyl aminopeptidase 3, mitochondrial |
| YY2 | YY2 transcription factor |
| ZC2HC1C | zinc finger, C2HC-type containing 1C |
| ZNF141 | zinc finger protein 141 |
| ZNF197 | zinc finger protein 197 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF442 | zinc finger protein 442 |
| ZNF573 | zinc finger protein 573 |
