| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the clozapine-5226 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACRV1 | acrosomal vesicle protein 1 |
| ACTA1 | actin, alpha 1, skeletal muscle |
| ADAM22 | ADAM metallopeptidase domain 22 |
| ADAP2 | ArfGAP with dual PH domains 2 |
| ANK2 | ankyrin 2, neuronal |
| APP | amyloid beta (A4) precursor protein |
| ARMC4 | armadillo repeat containing 4 |
| ASPH | aspartate beta-hydroxylase |
| C21ORF2 | chromosome 21 open reading frame 2 |
| C7ORF69 | chromosome 7 open reading frame 69 |
| CASKIN2 | CASK interacting protein 2 |
| CCPG1 | cell cycle progression 1 |
| CD52 | CD52 molecule |
| CD6 | CD6 molecule |
| CD83 | CD83 molecule |
| CDH8 | cadherin 8, type 2 |
| CDHR2 | cadherin-related family member 2 |
| CDON | cell adhesion associated, oncogene regulated |
| CFAP69 | cilia and flagella associated protein 69 |
| CHRNB2 | cholinergic receptor, nicotinic, beta 2 (neuronal) |
| CLCN7 | chloride channel, voltage-sensitive 7 |
| CXORF21 | chromosome X open reading frame 21 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
| DOK4 | docking protein 4 |
| DRD1 | dopamine receptor D1 |
| DRD2 | dopamine receptor D2 |
| DSC3 | desmocollin 3 |
| EFNB3 | ephrin-B3 |
| EPHA3 | EPH receptor A3 |
| FLJ21369 | uncharacterized protein FLJ21369 |
| FSCN1 | fascin actin-bundling protein 1 |
| FUT6 | fucosyltransferase 6 (alpha (1,3) fucosyltransferase) |
| GFI1 | growth factor independent 1 transcription repressor |
| GNPTAB | N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 |
| HCAR3 | hydroxycarboxylic acid receptor 3 |
| HOXA10 | homeobox A10 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IGLJ3 | immunoglobulin lambda joining 3 |
| IL12RB1 | interleukin 12 receptor, beta 1 |
| IRF9 | interferon regulatory factor 9 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
| ITGA8 | integrin, alpha 8 |
| ITGAL | integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) |
| KALRN | kalirin, RhoGEF kinase |
| KCNJ1 | potassium channel, inwardly rectifying subfamily J, member 1 |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| KIR2DL5A | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A |
| LEPR | leptin receptor |
| LIN7A | lin-7 homolog A (C. elegans) |
| LMF2 | lipase maturation factor 2 |
| MAN1A2 | mannosidase, alpha, class 1A, member 2 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 |
| MIOS | missing oocyte, meiosis regulator, homolog (Drosophila) |
| MMRN2 | multimerin 2 |
| MSL3 | male-specific lethal 3 homolog (Drosophila) |
| NDOR1 | NADPH dependent diflavin oxidoreductase 1 |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NME5 | NME/NM23 family member 5 |
| NTF3 | neurotrophin 3 |
| OXCT2 | 3-oxoacid CoA transferase 2 |
| PAK4 | p21 protein (Cdc42/Rac)-activated kinase 4 |
| PBX2 | pre-B-cell leukemia homeobox 2 |
| PCDHA5 | protocadherin alpha 5 |
| PDAP1 | PDGFA associated protein 1 |
| PDPR | pyruvate dehydrogenase phosphatase regulatory subunit |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha |
| PRKCE | protein kinase C, epsilon |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| RASGRP2 | RAS guanyl releasing protein 2 (calcium and DAG-regulated) |
| RBM26 | RNA binding motif protein 26 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats |
| RPS3A | ribosomal protein S3A |
| RUNX1 | runt-related transcription factor 1 |
| RUSC2 | RUN and SH3 domain containing 2 |
| S100A7 | S100 calcium binding protein A7 |
| SDC3 | syndecan 3 |
| SFRP4 | secreted frizzled-related protein 4 |
| SGK2 | serum/glucocorticoid regulated kinase 2 |
| SH3D21 | SH3 domain containing 21 |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
| SLC35A2 | solute carrier family 35 (UDP-galactose transporter), member A2 |
| SOCS3 | suppressor of cytokine signaling 3 |
| SPTLC3 | serine palmitoyltransferase, long chain base subunit 3 |
| SRGAP3 | SLIT-ROBO Rho GTPase activating protein 3 |
| SSX1 | synovial sarcoma, X breakpoint 1 |
| SULT4A1 | sulfotransferase family 4A, member 1 |
| TAF9B | TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa |
| TFEB | transcription factor EB |
| TIGD6 | tigger transposable element derived 6 |
| TMLHE | trimethyllysine hydroxylase, epsilon |
| TRAK1 | trafficking protein, kinesin binding 1 |
| TRPC1 | transient receptor potential cation channel, subfamily C, member 1 |
| USP2 | ubiquitin specific peptidase 2 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZSCAN18 | zinc finger and SCAN domain containing 18 |
| Symbol | Name |
|---|---|
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta |
| ARHGDIG | Rho GDP dissociation inhibitor (GDI) gamma |
| ARSB | arylsulfatase B |
| BRINP2 | bone morphogenetic protein/retinoic acid inducible neural-specific 2 |
| C1ORF105 | chromosome 1 open reading frame 105 |
| C1ORF35 | chromosome 1 open reading frame 35 |
| CAMK4 | calcium/calmodulin-dependent protein kinase IV |
| CCZ1B | CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae) |
| CEP85 | centrosomal protein 85kDa |
| CGA | glycoprotein hormones, alpha polypeptide |
| CHKB | choline kinase beta |
| CLDN15 | claudin 15 |
| COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 |
| CPSF7 | cleavage and polyadenylation specific factor 7, 59kDa |
| CRYBB2P1 | crystallin, beta B2 pseudogene 1 |
| CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 |
| CUL9 | cullin 9 |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| DCAF13 | DDB1 and CUL4 associated factor 13 |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 |
| ELOVL4 | ELOVL fatty acid elongase 4 |
| FLCN | folliculin |
| FMO4 | flavin containing monooxygenase 4 |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GCHFR | GTP cyclohydrolase I feedback regulator |
| GPR1 | G protein-coupled receptor 1 |
| GPR19 | G protein-coupled receptor 19 |
| GSTTP1 | glutathione S-transferase theta pseudogene 1 |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HDAC4 | histone deacetylase 4 |
| HIST1H2AI | histone cluster 1, H2ai |
| HIST1H2BO | histone cluster 1, H2bo |
| HIST2H2AA3 | histone cluster 2, H2aa3 |
| HOXA4 | homeobox A4 |
| IGFLR1 | IGF-like family receptor 1 |
| INPP1 | inositol polyphosphate-1-phosphatase |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KDM5C | lysine (K)-specific demethylase 5C |
| LOC202181 | SUMO-interacting motifs containing 1 pseudogene |
| LRRC37A3 | leucine rich repeat containing 37, member A3 |
| LY6D | lymphocyte antigen 6 complex, locus D |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MAPKBP1 | mitogen-activated protein kinase binding protein 1 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MINOS1P1 | mitochondrial inner membrane organizing system 1 pseudogene 1 |
| MMP3 | matrix metallopeptidase 3 |
| MRPL41 | mitochondrial ribosomal protein L41 |
| MTA2 | metastasis associated 1 family, member 2 |
| NARFL | nuclear prelamin A recognition factor-like |
| NIPAL2 | NIPA-like domain containing 2 |
| NR1H3 | nuclear receptor subfamily 1, group H, member 3 |
| NRSN2 | neurensin 2 |
| NXPH4 | neurexophilin 4 |
| PCDHA6 | protocadherin alpha 6 |
| PCDHB3 | protocadherin beta 3 |
| PCDHGB5 | protocadherin gamma subfamily B, 5 |
| PHACTR4 | phosphatase and actin regulator 4 |
| PLEKHA2 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 |
| PTPRE | protein tyrosine phosphatase, receptor type, E |
| QSER1 | glutamine and serine rich 1 |
| R3HCC1L | R3H domain and coiled-coil containing 1-like |
| RAB36 | RAB36, member RAS oncogene family |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RIBC2 | RIB43A domain with coiled-coils 2 |
| RIN1 | Ras and Rab interactor 1 |
| RNF2 | ring finger protein 2 |
| RNF43 | ring finger protein 43 |
| SECTM1 | secreted and transmembrane 1 |
| SLC12A9 | solute carrier family 12, member 9 |
| SLC16A10 | solute carrier family 16 (aromatic amino acid transporter), member 10 |
| SLC16A6 | solute carrier family 16, member 6 |
| SLC46A3 | solute carrier family 46, member 3 |
| SNAPC2 | small nuclear RNA activating complex, polypeptide 2, 45kDa |
| SP1 | Sp1 transcription factor |
| STON1 | stonin 1 |
| STRA6 | stimulated by retinoic acid 6 |
| SYTL2 | synaptotagmin-like 2 |
| TAB1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 |
| TARP | TCR gamma alternate reading frame protein |
| TMEM212 | transmembrane protein 212 |
| TMEM45A | transmembrane protein 45A |
| TRAF3IP1 | TNF receptor-associated factor 3 interacting protein 1 |
| TRIM36 | tripartite motif containing 36 |
| VPS11 | vacuolar protein sorting 11 homolog (S. cerevisiae) |
| WDR91 | WD repeat domain 91 |
| WFDC2 | WAP four-disulfide core domain 2 |
| YIF1B | Yip1 interacting factor homolog B (S. cerevisiae) |
| ZAK | sterile alpha motif and leucine zipper containing kinase AZK |
| ZBTB39 | zinc finger and BTB domain containing 39 |
| ZNF34 | zinc finger protein 34 |
| ZNF446 | zinc finger protein 446 |
| ZNF750 | zinc finger protein 750 |
| ZNF767P | zinc finger family member 767, pseudogene |
