| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the clozapine-5265 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
| ACSF2 | acyl-CoA synthetase family member 2 |
| AIPL1 | aryl hydrocarbon receptor interacting protein-like 1 |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
| ARAP1 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 |
| ARID3B | AT rich interactive domain 3B (BRIGHT-like) |
| ARTN | artemin |
| ATM | ATM serine/threonine kinase |
| CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
| CD52 | CD52 molecule |
| CFLAR | CASP8 and FADD-like apoptosis regulator |
| CHRNA2 | cholinergic receptor, nicotinic, alpha 2 (neuronal) |
| CLCN4 | chloride channel, voltage-sensitive 4 |
| CLDN11 | claudin 11 |
| CTNS | cystinosin, lysosomal cystine transporter |
| DCN | decorin |
| DMXL2 | Dmx-like 2 |
| DOPEY2 | dopey family member 2 |
| DPF1 | D4, zinc and double PHD fingers family 1 |
| DRD2 | dopamine receptor D2 |
| DUSP4 | dual specificity phosphatase 4 |
| EFNB3 | ephrin-B3 |
| EHBP1L1 | EH domain binding protein 1-like 1 |
| ENTPD1 | ectonucleoside triphosphate diphosphohydrolase 1 |
| EXOC7 | exocyst complex component 7 |
| EYA3 | EYA transcriptional coactivator and phosphatase 3 |
| FLRT2 | fibronectin leucine rich transmembrane protein 2 |
| FOXG1 | forkhead box G1 |
| GGT1 | gamma-glutamyltransferase 1 |
| GM2A | GM2 ganglioside activator |
| GOLGA2 | golgin A2 |
| GPR137 | G protein-coupled receptor 137 |
| GPR157 | G protein-coupled receptor 157 |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HCN2 | hyperpolarization activated cyclic nucleotide gated potassium channel 2 |
| HDAC7 | histone deacetylase 7 |
| HFE | hemochromatosis |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) |
| HSPG2 | heparan sulfate proteoglycan 2 |
| IL6ST | interleukin 6 signal transducer |
| INSIG1 | insulin induced gene 1 |
| JUN | jun proto-oncogene |
| KLRD1 | killer cell lectin-like receptor subfamily D, member 1 |
| LDLR | low density lipoprotein receptor |
| LRRC1 | leucine rich repeat containing 1 |
| LRRC37A3 | leucine rich repeat containing 37, member A3 |
| LSS | lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) |
| MAP1LC3C | microtubule-associated protein 1 light chain 3 gamma |
| MAP4 | microtubule-associated protein 4 |
| MARK4 | MAP/microtubule affinity-regulating kinase 4 |
| MIR622 | microRNA 622 |
| MR1 | major histocompatibility complex, class I-related |
| MTSS1L | metastasis suppressor 1-like |
| N4BP2L2-IT2 | N4BPL2 intronic transcript 2 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NFATC1 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NPR2 | natriuretic peptide receptor 2 |
| OXCT2 | 3-oxoacid CoA transferase 2 |
| PCDH7 | protocadherin 7 |
| PCDHGA8 | protocadherin gamma subfamily A, 8 |
| PER2 | period circadian clock 2 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PKNOX2 | PBX/knotted 1 homeobox 2 |
| PLA2G3 | phospholipase A2, group III |
| PLTP | phospholipid transfer protein |
| PODXL2 | podocalyxin-like 2 |
| PPFIBP2 | PTPRF interacting protein, binding protein 2 (liprin beta 2) |
| PVT1 | Pvt1 oncogene (non-protein coding) |
| RAB3GAP2 | RAB3 GTPase activating protein subunit 2 (non-catalytic) |
| RAB6B | RAB6B, member RAS oncogene family |
| RBL2 | retinoblastoma-like 2 |
| RNF208 | ring finger protein 208 |
| RPL35A | ribosomal protein L35a |
| S100A8 | S100 calcium binding protein A8 |
| SARM1 | sterile alpha and TIR motif containing 1 |
| SCN10A | sodium channel, voltage gated, type X alpha subunit |
| SERPINI2 | serpin peptidase inhibitor, clade I (pancpin), member 2 |
| SHOX2 | short stature homeobox 2 |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
| SLC24A1 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 |
| SLC39A9 | solute carrier family 39, member 9 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SLC9A3R2 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 |
| SRGAP3 | SLIT-ROBO Rho GTPase activating protein 3 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| SYNJ2 | synaptojanin 2 |
| TBC1D22A | TBC1 domain family, member 22A |
| THBD | thrombomodulin |
| TREX1 | three prime repair exonuclease 1 |
| UNC119 | unc-119 homolog (C. elegans) |
| VN1R1 | vomeronasal 1 receptor 1 |
| XIST | X inactive specific transcript (non-protein coding) |
| ZER1 | zyg-11 related, cell cycle regulator |
| ZNF76 | zinc finger protein 76 |
| Symbol | Name |
|---|---|
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 |
| ADAM2 | ADAM metallopeptidase domain 2 |
| AOC2 | amine oxidase, copper containing 2 (retina-specific) |
| ARC | activity-regulated cytoskeleton-associated protein |
| ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 |
| ARMC4 | armadillo repeat containing 4 |
| ARMC6 | armadillo repeat containing 6 |
| ATP10D | ATPase, class V, type 10D |
| BCO1 | beta-carotene oxygenase 1 |
| C14ORF79 | chromosome 14 open reading frame 79 |
| CAMK4 | calcium/calmodulin-dependent protein kinase IV |
| CCRN4L | CCR4 carbon catabolite repression 4-like (S. cerevisiae) |
| CDC37 | cell division cycle 37 |
| CDK20 | cyclin-dependent kinase 20 |
| CDON | cell adhesion associated, oncogene regulated |
| CFAP69 | cilia and flagella associated protein 69 |
| CIDEC | cell death-inducing DFFA-like effector c |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| CNR2 | cannabinoid receptor 2 (macrophage) |
| COPZ2 | coatomer protein complex, subunit zeta 2 |
| CRLF1 | cytokine receptor-like factor 1 |
| CTAGE1 | cutaneous T-cell lymphoma-associated antigen 1 |
| CXXC4 | CXXC finger protein 4 |
| DEF6 | differentially expressed in FDCP 6 homolog (mouse) |
| DMTN | dematin actin binding protein |
| DNAH17 | dynein, axonemal, heavy chain 17 |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| EAF2 | ELL associated factor 2 |
| EFNA3 | ephrin-A3 |
| ELSPBP1 | epididymal sperm binding protein 1 |
| EN2 | engrailed homeobox 2 |
| ERCC6 | excision repair cross-complementation group 6 |
| FBXO31 | F-box protein 31 |
| FGL1 | fibrinogen-like 1 |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FOSL1 | FOS-like antigen 1 |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) |
| GNG3 | guanine nucleotide binding protein (G protein), gamma 3 |
| GSTP1 | glutathione S-transferase pi 1 |
| HDAC11 | histone deacetylase 11 |
| HIST1H2BO | histone cluster 1, H2bo |
| HPN | hepsin |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 |
| IFI27 | interferon, alpha-inducible protein 27 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IL2 | interleukin 2 |
| IL22 | interleukin 22 |
| ITGA8 | integrin, alpha 8 |
| KCNN2 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 |
| KCNQ3 | potassium channel, voltage gated KQT-like subfamily Q, member 3 |
| KIF13B | kinesin family member 13B |
| KIF5A | kinesin family member 5A |
| KLF2 | Kruppel-like factor 2 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) |
| KREMEN2 | kringle containing transmembrane protein 2 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 |
| LHX1 | LIM homeobox 1 |
| LOC390998 | ribosomal protein L10 pseudogene |
| LRP2 | low density lipoprotein receptor-related protein 2 |
| MADCAM1 | mucosal vascular addressin cell adhesion molecule 1 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MFAP2 | microfibrillar-associated protein 2 |
| MMP2 | matrix metallopeptidase 2 |
| MYOZ3 | myozenin 3 |
| NEUROD4 | neuronal differentiation 4 |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| NTF3 | neurotrophin 3 |
| OR12D2 | olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene) |
| OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
| PCDHA5 | protocadherin alpha 5 |
| PDK2 | pyruvate dehydrogenase kinase, isozyme 2 |
| PDPR | pyruvate dehydrogenase phosphatase regulatory subunit |
| PHEX | phosphate regulating endopeptidase homolog, X-linked |
| POLR3D | polymerase (RNA) III (DNA directed) polypeptide D, 44kDa |
| PRKCE | protein kinase C, epsilon |
| RAB30 | RAB30, member RAS oncogene family |
| RASSF2 | Ras association (RalGDS/AF-6) domain family member 2 |
| RCAN3 | RCAN family member 3 |
| RFPL3 | ret finger protein-like 3 |
| RGS20 | regulator of G-protein signaling 20 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
| SIX1 | SIX homeobox 1 |
| ST5 | suppression of tumorigenicity 5 |
| STIM1 | stromal interaction molecule 1 |
| STK25 | serine/threonine kinase 25 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TCTN2 | tectonic family member 2 |
| TRMT44 | tRNA methyltransferase 44 homolog (S. cerevisiae) |
| TSGA10 | testis specific, 10 |
| TUBA3C | tubulin, alpha 3c |
| TUBA4B | tubulin, alpha 4b |
| USB1 | U6 snRNA biogenesis 1 |
| VASH1 | vasohibin 1 |
| YIF1B | Yip1 interacting factor homolog B (S. cerevisiae) |
| YY2 | YY2 transcription factor |
| ZBTB25 | zinc finger and BTB domain containing 25 |
| ZNF205 | zinc finger protein 205 |
| ZNF747 | zinc finger protein 747 |
