| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the clozapine-5589 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAM17 | ADAM metallopeptidase domain 17 |
| ADAM22 | ADAM metallopeptidase domain 22 |
| AGMAT | agmatine ureohydrolase (agmatinase) |
| AKAP8L | A kinase (PRKA) anchor protein 8-like |
| ANKRD26 | ankyrin repeat domain 26 |
| APAF1 | apoptotic peptidase activating factor 1 |
| APC | adenomatous polyposis coli |
| ARHGAP28 | Rho GTPase activating protein 28 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) |
| ART1 | ADP-ribosyltransferase 1 |
| ASIC4 | acid sensing (proton gated) ion channel family member 4 |
| ATAT1 | alpha tubulin acetyltransferase 1 |
| ATP10B | ATPase, class V, type 10B |
| B4GALT6 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 |
| BMP8B | bone morphogenetic protein 8b |
| CA1 | carbonic anhydrase I |
| CCDC6 | coiled-coil domain containing 6 |
| CCNG2 | cyclin G2 |
| CCZ1 | CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae) |
| CD47 | CD47 molecule |
| CEP295 | centrosomal protein 295kDa |
| CLEC4E | C-type lectin domain family 4, member E |
| CLGN | calmegin |
| CLTC | clathrin, heavy chain (Hc) |
| COL4A2 | collagen, type IV, alpha 2 |
| CPEB3 | cytoplasmic polyadenylation element binding protein 3 |
| CYLD | cylindromatosis (turban tumor syndrome) |
| DBR1 | debranching RNA lariats 1 |
| DMXL2 | Dmx-like 2 |
| DNAH7 | dynein, axonemal, heavy chain 7 |
| FBXL18 | F-box and leucine-rich repeat protein 18 |
| FBXO2 | F-box protein 2 |
| FGFR1OP | FGFR1 oncogene partner |
| FH | fumarate hydratase |
| FLJ11292 | |
| FSTL1 | follistatin-like 1 |
| GLYR1 | glyoxylate reductase 1 homolog (Arabidopsis) |
| GNAS | GNAS complex locus |
| GREB1 | growth regulation by estrogen in breast cancer 1 |
| HCN4 | hyperpolarization activated cyclic nucleotide gated potassium channel 4 |
| HDAC7 | histone deacetylase 7 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) |
| HUS1 | HUS1 checkpoint homolog (S. pombe) |
| ING4 | inhibitor of growth family, member 4 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
| KANK1 | KN motif and ankyrin repeat domains 1 |
| KCTD17 | potassium channel tetramerization domain containing 17 |
| KIF25-AS1 | KIF25 antisense RNA 1 |
| KLHL22 | kelch-like family member 22 |
| LAMA4 | laminin, alpha 4 |
| LRP12 | low density lipoprotein receptor-related protein 12 |
| MAPK10 | mitogen-activated protein kinase 10 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MFSD7 | major facilitator superfamily domain containing 7 |
| MORN1 | MORN repeat containing 1 |
| MTHFR | methylenetetrahydrofolate reductase (NAD(P)H) |
| MTSS1L | metastasis suppressor 1-like |
| MYBPC3 | myosin binding protein C, cardiac |
| NOVA2 | neuro-oncological ventral antigen 2 |
| NTM | neurotrimin |
| OR52A1 | olfactory receptor, family 52, subfamily A, member 1 |
| PGK1 | phosphoglycerate kinase 1 |
| PIGN | phosphatidylinositol glycan anchor biosynthesis, class N |
| PIK3CD | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta |
| PMEL | premelanosome protein |
| POU2F2 | POU class 2 homeobox 2 |
| PRAMEF11 | PRAME family member 11 |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 |
| PVR | poliovirus receptor |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 |
| RNF19B | ring finger protein 19B |
| RORC | RAR-related orphan receptor C |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
| SCLY | selenocysteine lyase |
| SH3GL3 | SH3-domain GRB2-like 3 |
| SIRT5 | sirtuin 5 |
| SLC17A7 | solute carrier family 17 (vesicular glutamate transporter), member 7 |
| SPG20 | spastic paraplegia 20 (Troyer syndrome) |
| SRSF7 | serine/arginine-rich splicing factor 7 |
| TBX3 | T-box 3 |
| TBXA2R | thromboxane A2 receptor |
| THRB | thyroid hormone receptor, beta |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) |
| TMEM38B | transmembrane protein 38B |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
| TRBC1 | T cell receptor beta constant 1 |
| TRMT44 | tRNA methyltransferase 44 homolog (S. cerevisiae) |
| TUBGCP2 | tubulin, gamma complex associated protein 2 |
| UBE2B | ubiquitin-conjugating enzyme E2B |
| UBOX5 | U-box domain containing 5 |
| UGT2B28 | UDP glucuronosyltransferase 2 family, polypeptide B28 |
| UTP18 | UTP18 small subunit (SSU) processome component homolog (yeast) |
| YIF1B | Yip1 interacting factor homolog B (S. cerevisiae) |
| YY2 | YY2 transcription factor |
| ZDHHC17 | zinc finger, DHHC-type containing 17 |
| ZFYVE9 | zinc finger, FYVE domain containing 9 |
| ZNF76 | zinc finger protein 76 |
| Symbol | Name |
|---|---|
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 |
| ABLIM3 | actin binding LIM protein family, member 3 |
| ACSF2 | acyl-CoA synthetase family member 2 |
| ADAMTS13 | ADAM metallopeptidase with thrombospondin type 1 motif, 13 |
| ADAMTSL3 | ADAMTS-like 3 |
| AHNAK2 | AHNAK nucleoprotein 2 |
| ARMCX4 | armadillo repeat containing, X-linked 4 |
| ARPIN | actin-related protein 2/3 complex inhibitor |
| ASPN | asporin |
| ATP10D | ATPase, class V, type 10D |
| BGLAP | bone gamma-carboxyglutamate (gla) protein |
| C16ORF45 | chromosome 16 open reading frame 45 |
| C22ORF46 | chromosome 22 open reading frame 46 |
| C2ORF54 | chromosome 2 open reading frame 54 |
| CA5BP1 | carbonic anhydrase VB pseudogene 1 |
| CCP110 | centriolar coiled coil protein 110kDa |
| CD1A | CD1a molecule |
| CD3D | CD3d molecule, delta (CD3-TCR complex) |
| CD79B | CD79b molecule, immunoglobulin-associated beta |
| CFAP69 | cilia and flagella associated protein 69 |
| DLK2 | delta-like 2 homolog (Drosophila) |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DUSP13 | dual specificity phosphatase 13 |
| EFNA3 | ephrin-A3 |
| FAM110B | family with sequence similarity 110, member B |
| FAM120C | family with sequence similarity 120C |
| FANCE | Fanconi anemia, complementation group E |
| FBXO31 | F-box protein 31 |
| FGF6 | fibroblast growth factor 6 |
| FRMD1 | FERM domain containing 1 |
| GABRA2 | gamma-aminobutyric acid (GABA) A receptor, alpha 2 |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GLB1L | galactosidase, beta 1-like |
| GLI3 | GLI family zinc finger 3 |
| GNL1 | guanine nucleotide binding protein-like 1 |
| GPRIN2 | G protein regulated inducer of neurite outgrowth 2 |
| GRPR | gastrin-releasing peptide receptor |
| HLA-DRB1 | major histocompatibility complex, class II, DR beta 1 |
| HOXD11 | homeobox D11 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 |
| IL2 | interleukin 2 |
| IPO13 | importin 13 |
| IQCC | IQ motif containing C |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| KDM5C | lysine (K)-specific demethylase 5C |
| KIAA0319L | KIAA0319-like |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| MALL | mal, T-cell differentiation protein-like |
| MMP2 | matrix metallopeptidase 2 |
| MYO1F | myosin IF |
| NACA2 | nascent polypeptide-associated complex alpha subunit 2 |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NTF3 | neurotrophin 3 |
| NUDT18 | nudix (nucleoside diphosphate linked moiety X)-type motif 18 |
| OVGP1 | oviductal glycoprotein 1, 120kDa |
| P2RY4 | pyrimidinergic receptor P2Y, G-protein coupled, 4 |
| PDE8B | phosphodiesterase 8B |
| PIGQ | phosphatidylinositol glycan anchor biosynthesis, class Q |
| PITPNM1 | phosphatidylinositol transfer protein, membrane-associated 1 |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| PLSCR4 | phospholipid scramblase 4 |
| POLM | polymerase (DNA directed), mu |
| PRF1 | perforin 1 (pore forming protein) |
| QPCT | glutaminyl-peptide cyclotransferase |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RFPL3 | ret finger protein-like 3 |
| RHBG | Rh family, B glycoprotein (gene/pseudogene) |
| RIN1 | Ras and Rab interactor 1 |
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 |
| RNASE2 | ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) |
| RNPEPL1 | arginyl aminopeptidase (aminopeptidase B)-like 1 |
| RPL10L | ribosomal protein L10-like |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SGCE | sarcoglycan, epsilon |
| SHARPIN | SHANK-associated RH domain interactor |
| SIPA1 | signal-induced proliferation-associated 1 |
| SLC2A11 | solute carrier family 2 (facilitated glucose transporter), member 11 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 |
| SLIT2 | slit homolog 2 (Drosophila) |
| SMARCD3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 |
| SNTA1 | syntrophin, alpha 1 |
| SSTR4 | somatostatin receptor 4 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| TMEM212 | transmembrane protein 212 |
| TMEM39B | transmembrane protein 39B |
| TRPM4 | transient receptor potential cation channel, subfamily M, member 4 |
| VEGFC | vascular endothelial growth factor C |
| VIM | vimentin |
| VPS9D1 | VPS9 domain containing 1 |
| WDR62 | WD repeat domain 62 |
| WFDC2 | WAP four-disulfide core domain 2 |
| WLS | wntless Wnt ligand secretion mediator |
| ZFHX2 | zinc finger homeobox 2 |
| ZNF16 | zinc finger protein 16 |
| ZNF204P | zinc finger protein 204, pseudogene |
| ZNF304 | zinc finger protein 304 |
| ZNF551 | zinc finger protein 551 |
| ZNF639 | zinc finger protein 639 |
