| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the clozapine-6188 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 |
| ADAMTS7 | ADAM metallopeptidase with thrombospondin type 1 motif, 7 |
| ADCY9 | adenylate cyclase 9 |
| ADORA1 | adenosine A1 receptor |
| ALX4 | ALX homeobox 4 |
| APPBP2 | amyloid beta precursor protein (cytoplasmic tail) binding protein 2 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) |
| ARHGAP24 | Rho GTPase activating protein 24 |
| ARSA | arylsulfatase A |
| BCL6 | B-cell CLL/lymphoma 6 |
| BMP7 | bone morphogenetic protein 7 |
| C1ORF105 | chromosome 1 open reading frame 105 |
| CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit |
| CARD10 | caspase recruitment domain family, member 10 |
| CCR8 | chemokine (C-C motif) receptor 8 |
| CDK10 | cyclin-dependent kinase 10 |
| CFAP45 | cilia and flagella associated protein 45 |
| CHRNA6 | cholinergic receptor, nicotinic, alpha 6 (neuronal) |
| COL10A1 | collagen, type X, alpha 1 |
| COL4A6 | collagen, type IV, alpha 6 |
| CSF1 | colony stimulating factor 1 (macrophage) |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 |
| CTNNBIP1 | catenin, beta interacting protein 1 |
| CYLD | cylindromatosis (turban tumor syndrome) |
| DAPK3 | death-associated protein kinase 3 |
| DCAF17 | DDB1 and CUL4 associated factor 17 |
| DDR1 | discoidin domain receptor tyrosine kinase 1 |
| DLG3 | discs, large homolog 3 (Drosophila) |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| DOCK1 | dedicator of cytokinesis 1 |
| DVL2 | dishevelled segment polarity protein 2 |
| EIF4EBP2 | eukaryotic translation initiation factor 4E binding protein 2 |
| EPS8L1 | EPS8-like 1 |
| ERC2-IT1 | ERC2 intronic transcript 1 |
| EXT1 | exostosin glycosyltransferase 1 |
| EXTL3 | exostosin-like glycosyltransferase 3 |
| FAM50B | family with sequence similarity 50, member B |
| FUT2 | fucosyltransferase 2 (secretor status included) |
| FUT6 | fucosyltransferase 6 (alpha (1,3) fucosyltransferase) |
| GABBR2 | gamma-aminobutyric acid (GABA) B receptor, 2 |
| GK3P | glycerol kinase 3 pseudogene |
| GPR135 | G protein-coupled receptor 135 |
| GPX2 | glutathione peroxidase 2 |
| GRK5 | G protein-coupled receptor kinase 5 |
| GTPBP1 | GTP binding protein 1 |
| HNMT | histamine N-methyltransferase |
| HSF2BP | heat shock transcription factor 2 binding protein |
| HSPA1L | heat shock 70kDa protein 1-like |
| IFNW1 | interferon, omega 1 |
| KHK | ketohexokinase (fructokinase) |
| KIAA0226L | KIAA0226-like |
| KIF1C | kinesin family member 1C |
| KLHL36 | kelch-like family member 36 |
| KRT6B | keratin 6B, type II |
| KRT75 | keratin 75, type II |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LTBP2 | latent transforming growth factor beta binding protein 2 |
| MAL | mal, T-cell differentiation protein |
| MED25 | mediator complex subunit 25 |
| MMP17 | matrix metallopeptidase 17 (membrane-inserted) |
| MOGAT2 | monoacylglycerol O-acyltransferase 2 |
| MR1 | major histocompatibility complex, class I-related |
| MYBPC1 | myosin binding protein C, slow type |
| NEBL | nebulette |
| NF2 | neurofibromin 2 (merlin) |
| NLRP1 | NLR family, pyrin domain containing 1 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| OLFML2B | olfactomedin-like 2B |
| OXCT2 | 3-oxoacid CoA transferase 2 |
| PAFAH2 | platelet-activating factor acetylhydrolase 2, 40kDa |
| PART1 | prostate androgen-regulated transcript 1 (non-protein coding) |
| PCNXL2 | pecanex-like 2 (Drosophila) |
| PFKFB2 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) |
| PLD2 | phospholipase D2 |
| PNMAL1 | paraneoplastic Ma antigen family-like 1 |
| PRLR | prolactin receptor |
| PVR | poliovirus receptor |
| REC8 | REC8 meiotic recombination protein |
| REM1 | RAS (RAD and GEM)-like GTP-binding 1 |
| RUFY3 | RUN and FYVE domain containing 3 |
| SEMA6B | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B |
| SH2D3A | SH2 domain containing 3A |
| SH3BP2 | SH3-domain binding protein 2 |
| SLC11A1 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 |
| SS18 | synovial sarcoma translocation, chromosome 18 |
| TGFBR1 | transforming growth factor, beta receptor 1 |
| TIMELESS | timeless circadian clock |
| TLK1 | tousled-like kinase 1 |
| TMEM53 | transmembrane protein 53 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase |
| TSC22D2 | TSC22 domain family, member 2 |
| UBOX5 | U-box domain containing 5 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) |
| ZER1 | zyg-11 related, cell cycle regulator |
| ZFX | zinc finger protein, X-linked |
| ZNF24 | zinc finger protein 24 |
| ZNF41 | zinc finger protein 41 |
| Symbol | Name |
|---|---|
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 |
| ACPP | acid phosphatase, prostate |
| ANKRD36 | ankyrin repeat domain 36 |
| ANXA3 | annexin A3 |
| APOBEC2 | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2 |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| ATP6V0E2 | ATPase, H+ transporting V0 subunit e2 |
| BAG4 | BCL2-associated athanogene 4 |
| BCAS3 | breast carcinoma amplified sequence 3 |
| BTBD18 | BTB (POZ) domain containing 18 |
| C1ORF56 | chromosome 1 open reading frame 56 |
| CALCOCO1 | calcium binding and coiled-coil domain 1 |
| CAPN5 | calpain 5 |
| CCDC85C | coiled-coil domain containing 85C |
| CD69 | CD69 molecule |
| CDIP1 | cell death-inducing p53 target 1 |
| CDKL3 | cyclin-dependent kinase-like 3 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CDR2L | cerebellar degeneration-related protein 2-like |
| CRY2 | cryptochrome circadian clock 2 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 |
| CXORF56 | chromosome X open reading frame 56 |
| CYP2B7P | cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 |
| DFNA5 | deafness, autosomal dominant 5 |
| DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
| ECHDC2 | enoyl CoA hydratase domain containing 2 |
| EDAR | ectodysplasin A receptor |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 |
| FAM127B | family with sequence similarity 127, member B |
| FAM131A | family with sequence similarity 131, member A |
| FKBP14 | FK506 binding protein 14, 22 kDa |
| GID4 | GID complex subunit 4 |
| GLTP | glycolipid transfer protein |
| GNB1L | guanine nucleotide binding protein (G protein), beta polypeptide 1-like |
| GNG3 | guanine nucleotide binding protein (G protein), gamma 3 |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| GNL1 | guanine nucleotide binding protein-like 1 |
| GPATCH2L | G patch domain containing 2-like |
| GPR35 | G protein-coupled receptor 35 |
| GPRIN2 | G protein regulated inducer of neurite outgrowth 2 |
| GRAMD1B | GRAM domain containing 1B |
| GSDMD | gasdermin D |
| HHLA3 | HERV-H LTR-associating 3 |
| HIST1H3H | histone cluster 1, H3h |
| HIST2H2AA3 | histone cluster 2, H2aa3 |
| IL11RA | interleukin 11 receptor, alpha |
| INF2 | inverted formin, FH2 and WH2 domain containing |
| IRF7 | interferon regulatory factor 7 |
| KIAA0319L | KIAA0319-like |
| KIAA1024 | KIAA1024 |
| KLF1 | Kruppel-like factor 1 (erythroid) |
| LAMB3 | laminin, beta 3 |
| LIN7B | lin-7 homolog B (C. elegans) |
| LINC00597 | long intergenic non-protein coding RNA 597 |
| LOC157562 | uncharacterized LOC157562 |
| LPPR2 | lipid phosphate phosphatase-related protein type 2 |
| LRRK1 | leucine-rich repeat kinase 1 |
| MAGEF1 | melanoma antigen family F1 |
| MED15 | mediator complex subunit 15 |
| MEGF8 | multiple EGF-like-domains 8 |
| MFSD11 | major facilitator superfamily domain containing 11 |
| MLYCD | malonyl-CoA decarboxylase |
| MRAS | muscle RAS oncogene homolog |
| MYO15A | myosin XVA |
| OMG | oligodendrocyte myelin glycoprotein |
| OVGP1 | oviductal glycoprotein 1, 120kDa |
| P2RY1 | purinergic receptor P2Y, G-protein coupled, 1 |
| PCBP4 | poly(rC) binding protein 4 |
| PGGT1B | protein geranylgeranyltransferase type I, beta subunit |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PNOC | prepronociceptin |
| PPP1R16B | protein phosphatase 1, regulatory subunit 16B |
| PRSS12 | protease, serine, 12 (neurotrypsin, motopsin) |
| PRY | PTPN13-like, Y-linked |
| PYGB | phosphorylase, glycogen; brain |
| RAB3A | RAB3A, member RAS oncogene family |
| RANBP17 | RAN binding protein 17 |
| REPS2 | RALBP1 associated Eps domain containing 2 |
| SEMA3G | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G |
| SLC16A6 | solute carrier family 16, member 6 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| STBD1 | starch binding domain 1 |
| TBC1D17 | TBC1 domain family, member 17 |
| TEX40 | testis expressed 40 |
| THBS4 | thrombospondin 4 |
| TSPYL2 | TSPY-like 2 |
| TUT1 | terminal uridylyl transferase 1, U6 snRNA-specific |
| TXNDC15 | thioredoxin domain containing 15 |
| UBE2O | ubiquitin-conjugating enzyme E2O |
| USP18 | ubiquitin specific peptidase 18 |
| USP32 | ubiquitin specific peptidase 32 |
| WDR62 | WD repeat domain 62 |
| ZBTB25 | zinc finger and BTB domain containing 25 |
| ZC3H12A | zinc finger CCCH-type containing 12A |
| ZNF137P | zinc finger protein 137, pseudogene |
| ZNF14 | zinc finger protein 14 |
| ZNF219 | zinc finger protein 219 |
| ZNF552 | zinc finger protein 552 |
