| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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200 genes differentially expressed following the clozapine-6988 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAMTS13 | ADAM metallopeptidase with thrombospondin type 1 motif, 13 |
| ADCK2 | aarF domain containing kinase 2 |
| ADRBK1 | adrenergic, beta, receptor kinase 1 |
| AGPAT3 | 1-acylglycerol-3-phosphate O-acyltransferase 3 |
| AMPD3 | adenosine monophosphate deaminase 3 |
| AMT | aminomethyltransferase |
| AQR | aquarius intron-binding spliceosomal factor |
| AUTS2 | autism susceptibility candidate 2 |
| CALML3 | calmodulin-like 3 |
| CCDC93 | coiled-coil domain containing 93 |
| CD4 | CD4 molecule |
| CD79B | CD79b molecule, immunoglobulin-associated beta |
| CFLAR | CASP8 and FADD-like apoptosis regulator |
| COL7A1 | collagen, type VII, alpha 1 |
| CXORF21 | chromosome X open reading frame 21 |
| CYP2D6 | cytochrome P450, family 2, subfamily D, polypeptide 6 |
| DOK4 | docking protein 4 |
| DOK5 | docking protein 5 |
| DPYSL4 | dihydropyrimidinase-like 4 |
| DRD2 | dopamine receptor D2 |
| EFNA3 | ephrin-A3 |
| EMC1 | ER membrane protein complex subunit 1 |
| ENTPD1 | ectonucleoside triphosphate diphosphohydrolase 1 |
| ESR1 | estrogen receptor 1 |
| FGF4 | fibroblast growth factor 4 |
| FHL1 | four and a half LIM domains 1 |
| FLJ42627 | uncharacterized LOC645644 |
| FXYD2 | FXYD domain containing ion transport regulator 2 |
| GADD45G | growth arrest and DNA-damage-inducible, gamma |
| GLS | glutaminase |
| GNL3LP1 | guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1 |
| GPR137 | G protein-coupled receptor 137 |
| GRM1 | glutamate receptor, metabotropic 1 |
| HFE | hemochromatosis |
| HIST1H3B | histone cluster 1, H3b |
| HLA-DRB6 | major histocompatibility complex, class II, DR beta 6 (pseudogene) |
| HNMT | histamine N-methyltransferase |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| INADL | InaD-like (Drosophila) |
| INPP5B | inositol polyphosphate-5-phosphatase, 75kDa |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| ITGA10 | integrin, alpha 10 |
| JADE2 | jade family PHD finger 2 |
| JRK | Jrk homolog (mouse) |
| KDM5A | lysine (K)-specific demethylase 5A |
| LEPR | leptin receptor |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAPK10 | mitogen-activated protein kinase 10 |
| MED6 | mediator complex subunit 6 |
| MED9 | mediator complex subunit 9 |
| MGEA5 | meningioma expressed antigen 5 (hyaluronidase) |
| MYL10 | myosin, light chain 10, regulatory |
| NKTR | natural killer cell triggering receptor |
| NMT2 | N-myristoyltransferase 2 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| NTRK3 | neurotrophic tyrosine kinase, receptor, type 3 |
| PAQR6 | progestin and adipoQ receptor family member VI |
| PDE6B | phosphodiesterase 6B, cGMP-specific, rod, beta |
| PER1 | period circadian clock 1 |
| PLEKHA2 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| PTCRA | pre T-cell antigen receptor alpha |
| QKI | QKI, KH domain containing, RNA binding |
| RAD51B | RAD51 paralog B |
| RASAL2 | RAS protein activator like 2 |
| RGS12 | regulator of G-protein signaling 12 |
| RIMS3 | regulating synaptic membrane exocytosis 3 |
| RRBP1 | ribosome binding protein 1 |
| RSU1 | Ras suppressor protein 1 |
| RYR2 | ryanodine receptor 2 (cardiac) |
| SCAPER | S-phase cyclin A-associated protein in the ER |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SKIL | SKI-like proto-oncogene |
| SLC18A1 | solute carrier family 18 (vesicular monoamine transporter), member 1 |
| SLC30A3 | solute carrier family 30 (zinc transporter), member 3 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 |
| SNAI2 | snail family zinc finger 2 |
| SSX2IP | synovial sarcoma, X breakpoint 2 interacting protein |
| STAG3L1 | stromal antigen 3-like 1 (pseudogene) |
| SYBU | syntabulin (syntaxin-interacting) |
| SYNC | syncoilin, intermediate filament protein |
| TADA2A | transcriptional adaptor 2A |
| TAF6L | TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa |
| TAGLN3 | transgelin 3 |
| TAZ | tafazzin |
| TCHH | trichohyalin |
| TMEM63A | transmembrane protein 63A |
| TRAIP | TRAF interacting protein |
| VIPR1 | vasoactive intestinal peptide receptor 1 |
| WNT6 | wingless-type MMTV integration site family, member 6 |
| WWP2 | WW domain containing E3 ubiquitin protein ligase 2 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 |
| ZFX | zinc finger protein, X-linked |
| ZNF423 | zinc finger protein 423 |
| ZNF639 | zinc finger protein 639 |
| ZNF701 | zinc finger protein 701 |
| ZNF79 | zinc finger protein 79 |
| Symbol | Name |
|---|---|
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 |
| ANKRD36 | ankyrin repeat domain 36 |
| ANKS1A | ankyrin repeat and sterile alpha motif domain containing 1A |
| AP1B1 | adaptor-related protein complex 1, beta 1 subunit |
| ARHGAP5 | Rho GTPase activating protein 5 |
| ARHGEF5 | Rho guanine nucleotide exchange factor (GEF) 5 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| ATAD5 | ATPase family, AAA domain containing 5 |
| BRD1 | bromodomain containing 1 |
| C2ORF44 | chromosome 2 open reading frame 44 |
| C4ORF29 | chromosome 4 open reading frame 29 |
| CAPG | capping protein (actin filament), gelsolin-like |
| CCDC88C | coiled-coil domain containing 88C |
| CDK3 | cyclin-dependent kinase 3 |
| CDK5RAP2 | CDK5 regulatory subunit associated protein 2 |
| CEP131 | centrosomal protein 131kDa |
| CEP72 | centrosomal protein 72kDa |
| CHKB | choline kinase beta |
| CISH | cytokine inducible SH2-containing protein |
| CLASP1 | cytoplasmic linker associated protein 1 |
| CLEC16A | C-type lectin domain family 16, member A |
| CLSPN | claspin |
| CPPED1 | calcineurin-like phosphoesterase domain containing 1 |
| DNM1 | dynamin 1 |
| DSE | dermatan sulfate epimerase |
| ECHDC3 | enoyl CoA hydratase domain containing 3 |
| EVPL | envoplakin |
| FAM189B | family with sequence similarity 189, member B |
| FAM57A | family with sequence similarity 57, member A |
| FAM63A | family with sequence similarity 63, member A |
| FBXO31 | F-box protein 31 |
| FBXO46 | F-box protein 46 |
| FCHSD2 | FCH and double SH3 domains 2 |
| GABPA | GA binding protein transcription factor, alpha subunit 60kDa |
| GALK1 | galactokinase 1 |
| GCHFR | GTP cyclohydrolase I feedback regulator |
| GLB1L2 | galactosidase, beta 1-like 2 |
| GMIP | GEM interacting protein |
| GPRC5C | G protein-coupled receptor, class C, group 5, member C |
| HINFP | histone H4 transcription factor |
| HIST1H2AJ | histone cluster 1, H2aj |
| IGFLR1 | IGF-like family receptor 1 |
| INPP5A | inositol polyphosphate-5-phosphatase, 40kDa |
| IRX4 | iroquois homeobox 4 |
| JMJD4 | jumonji domain containing 4 |
| KATNBL1 | katanin p80 subunit B-like 1 |
| KIAA0232 | KIAA0232 |
| KLF3 | Kruppel-like factor 3 (basic) |
| LNPEP | leucyl/cystinyl aminopeptidase |
| LRRC37A2 | leucine rich repeat containing 37, member A2 |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| LY6D | lymphocyte antigen 6 complex, locus D |
| LZTR1 | leucine-zipper-like transcription regulator 1 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 |
| MEIS2 | Meis homeobox 2 |
| MITF | microphthalmia-associated transcription factor |
| MMP9 | matrix metallopeptidase 9 |
| MRPL2 | mitochondrial ribosomal protein L2 |
| MXD3 | MAX dimerization protein 3 |
| MYH9 | myosin, heavy chain 9, non-muscle |
| NDRG1 | N-myc downstream regulated 1 |
| NDRG4 | NDRG family member 4 |
| NDUFAF7 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 7 |
| NES | nestin |
| OTUD3 | OTU deubiquitinase 3 |
| OXTR | oxytocin receptor |
| PARP16 | poly (ADP-ribose) polymerase family, member 16 |
| PCSK1N | proprotein convertase subtilisin/kexin type 1 inhibitor |
| PGP | phosphoglycolate phosphatase |
| PIGL | phosphatidylinositol glycan anchor biosynthesis, class L |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PNRC1 | proline-rich nuclear receptor coactivator 1 |
| PRODH | proline dehydrogenase (oxidase) 1 |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) |
| RNF123 | ring finger protein 123 |
| RRNAD1 | ribosomal RNA adenine dimethylase domain containing 1 |
| SCAMP4 | secretory carrier membrane protein 4 |
| SH2B3 | SH2B adaptor protein 3 |
| SLC12A7 | solute carrier family 12 (potassium/chloride transporter), member 7 |
| SNAPC2 | small nuclear RNA activating complex, polypeptide 2, 45kDa |
| SP140L | SP140 nuclear body protein-like |
| SPIDR | scaffolding protein involved in DNA repair |
| SPRYD7 | SPRY domain containing 7 |
| SRGAP2 | SLIT-ROBO Rho GTPase activating protein 2 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TMEM260 | transmembrane protein 260 |
| UBQLN4 | ubiquilin 4 |
| UNC119 | unc-119 homolog (C. elegans) |
| VAV1 | vav 1 guanine nucleotide exchange factor |
| WDR62 | WD repeat domain 62 |
| WDR91 | WD repeat domain 91 |
| ZNF282 | zinc finger protein 282 |
| ZNF324 | zinc finger protein 324 |
| ZNF510 | zinc finger protein 510 |
| ZNF710 | zinc finger protein 710 |
| ZNF8 | zinc finger protein 8 |
| ZSCAN31 | zinc finger and SCAN domain containing 31 |
