clozapine Gene Set

Dataset	GAD Gene-Disease Associations
Category	disease or phenotype associations
Type	disease
Description	A benzodiazepine that is 5H-dibenzo[b,e][1,4]diazepine substituted by a chloro group at position 8 and a 4-methylpiperazin-1-yl group at position 11. It is a second generation antipsychotic used in the treatment of psychiatric disorders like schizophrenia. (Chemical Entities of Biological Interest Ontology, CHEBI_3766)
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Genes

12 genes associated with the disease clozapine in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

Symbol	Name
ABCB1	ATP-binding cassette, sub-family B (MDR/TAP), member 1
CDH13	cadherin 13
CYP1A2	cytochrome P450, family 1, subfamily A, polypeptide 2
CYP2B6	cytochrome P450, family 2, subfamily B, polypeptide 6
CYP2C19	cytochrome P450, family 2, subfamily C, polypeptide 19
CYP2C9	cytochrome P450, family 2, subfamily C, polypeptide 9
CYP2D6	cytochrome P450, family 2, subfamily D, polypeptide 6
CYP3A5	cytochrome P450, family 3, subfamily A, polypeptide 5
CYP3A7	cytochrome P450, family 3, subfamily A, polypeptide 7
KIRREL3	kin of IRRE like 3 (Drosophila)
PPARD	peroxisome proliferator-activated receptor delta
PRKAR2B	protein kinase, cAMP-dependent, regulatory, type II, beta