clubfoot Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores
Category disease or phenotype associations
Type disease
Description OMIM mapping confirmed by DO. [SN]. (Human Disease Ontology, DOID_11836)
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Genes

102 genes co-occuring with the disease clubfoot in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
PITX1 paired-like homeodomain 1 1.99595
TBX4 T-box 4 1.86049
CHST14 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14 1.793
MYH3 myosin, heavy chain 3, skeletal muscle, embryonic 1.69633
TNNT3 troponin T type 3 (skeletal, fast) 1.572
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 1.57156
COL9A1 collagen, type IX, alpha 1 1.51721
HOXD13 homeobox D13 1.4588
HOXD10 homeobox D10 1.41052
TNNI2 troponin I type 2 (skeletal, fast) 1.33938
TNNC2 troponin C type 2 (fast) 1.31319
ZNF664 zinc finger protein 664 1.29702
GLI3 GLI family zinc finger 3 1.27999
TPM2 tropomyosin 2 (beta) 1.21305
SLC26A2 solute carrier family 26 (anion exchanger), member 2 1.15581
CHST3 carbohydrate (chondroitin 6) sulfotransferase 3 1.11687
MYH4 myosin, heavy chain 4, skeletal muscle 1.1009
HOXC11 homeobox C11 1.07614
HOXD12 homeobox D12 1.0463
ZFYVE27 zinc finger, FYVE domain containing 27 1.0442
WNT7A wingless-type MMTV integration site family, member 7A 1.02355
COL9A2 collagen, type IX, alpha 2 1.0206
HOXC5 homeobox C5 1.01512
MED25 mediator complex subunit 25 1.01047
NACA nascent polypeptide-associated complex alpha subunit 0.991909
FHL1 four and a half LIM domains 1 0.959542
COL3A1 collagen, type III, alpha 1 0.955361
FKBP8 FK506 binding protein 8, 38kDa 0.95369
MYH8 myosin, heavy chain 8, skeletal muscle, perinatal 0.941196
CHRNG cholinergic receptor, nicotinic, gamma (muscle) 0.920498
MYH1 myosin, heavy chain 1, skeletal muscle, adult 0.899103
SYNE1 spectrin repeat containing, nuclear envelope 1 0.889668
FLNB filamin B, beta 0.881472
FOXN3 forkhead box N3 0.878605
MATR3 matrin 3 0.865502
FREM1 FRAS1 related extracellular matrix 1 0.865502
EBP emopamil binding protein (sterol isomerase) 0.852402
PFDN4 prefoldin subunit 4 0.851992
ECEL1 endothelin converting enzyme-like 1 0.845031
RBM10 RNA binding motif protein 10 0.831508
CFLAR CASP8 and FADD-like apoptosis regulator 0.81059
NCOR2 nuclear receptor corepressor 2 0.801564
SNTA1 syntrophin, alpha 1 0.800744
CNTN1 contactin 1 0.754527
COL9A3 collagen, type IX, alpha 3 0.75412
MYH2 myosin, heavy chain 2, skeletal muscle, adult 0.753306
PTER phosphotriesterase related 0.745172
CHRND cholinergic receptor, nicotinic, delta (muscle) 0.713198
COL5A2 collagen, type V, alpha 2 0.711587
PIGN phosphatidylinositol glycan anchor biosynthesis, class N 0.641827
DOK7 docking protein 7 0.633563
CAND2 cullin-associated and neddylation-dissociated 2 (putative) 0.630813
TNNT1 troponin T type 1 (skeletal, slow) 0.62728
MYBPC1 myosin binding protein C, slow type 0.616312
EN1 engrailed homeobox 1 0.578494
RAPSN receptor-associated protein of the synapse 0.574605
COMP cartilage oligomeric matrix protein 0.562946
SOX9 SRY (sex determining region Y)-box 9 0.537344
GDAP1 ganglioside induced differentiation associated protein 1 0.534635
EED embryonic ectoderm development 0.528835
DHCR24 24-dehydrocholesterol reductase 0.526904
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon 0.522659
MATN3 matrilin 3 0.499997
CHRNA1 cholinergic receptor, nicotinic, alpha 1 (muscle) 0.487407
IGFBP6 insulin-like growth factor binding protein 6 0.485885
COL1A1 collagen, type I, alpha 1 0.477909
DSE dermatan sulfate epimerase 0.47753
LMX1B LIM homeobox transcription factor 1, beta 0.43753
GDF5 growth differentiation factor 5 0.433397
PEPD peptidase D 0.430768
IGLV2-14 immunoglobulin lambda variable 2-14 0.399334
NAIP NLR family, apoptosis inhibitory protein 0.386308
MSX1 msh homeobox 1 0.385565
TPM3 tropomyosin 3 0.378885
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) 0.354131
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A 0.353395
LMNA lamin A/C 0.344207
GAP43 growth associated protein 43 0.342739
GYPE glycophorin E (MNS blood group) 0.341639
FBN2 fibrillin 2 0.339073
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related) 0.332852
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6 0.320454
HOXD9 homeobox D9 0.304864
ACTA1 actin, alpha 1, skeletal muscle 0.298731
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) 0.298011
HOXA9 homeobox A9 0.289027
PGRMC1 progesterone receptor membrane component 1 0.259477
LIG3 ligase III, DNA, ATP-dependent 0.24715
MCM8 minichromosome maintenance complex component 8 0.241895
MUT methylmalonyl CoA mutase 0.240148
APAF1 apoptotic peptidase activating factor 1 0.232489
HNF1B HNF1 homeobox B 0.228679
COL2A1 collagen, type II, alpha 1 0.203604
PKD1P6 polycystic kidney disease 1 (autosomal dominant) pseudogene 6 0.198709
AGO2 argonaute RISC catalytic component 2 0.195501
RYR1 ryanodine receptor 1 (skeletal) 0.192657
CASP8 caspase 8, apoptosis-related cysteine peptidase 0.188022
FBN1 fibrillin 1 0.172038
SMN1 survival of motor neuron 1, telomeric 0.171785
MYOG myogenin (myogenic factor 4) 0.169812
MLX MLX, MAX dimerization protein 0.169571
KMT2A lysine (K)-specific methyltransferase 2A 0.167682