cobalt chloride-383 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the cobalt chloride-383 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD2 abhydrolase domain containing 2
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ARNTL aryl hydrocarbon receptor nuclear translocator-like
AXIN1 axin 1
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BTN2A1 butyrophilin, subfamily 2, member A1
C20ORF27 chromosome 20 open reading frame 27
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
CLDN17 claudin 17
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
COBL cordon-bleu WH2 repeat protein
COMMD9 COMM domain containing 9
CYLC1 cylicin, basic protein of sperm head cytoskeleton 1
DGKD diacylglycerol kinase, delta 130kDa
DHPS deoxyhypusine synthase
ECE1 endothelin converting enzyme 1
EDA2R ectodysplasin A2 receptor
EFNB3 ephrin-B3
EHMT1 euchromatic histone-lysine N-methyltransferase 1
FANCF Fanconi anemia, complementation group F
FASTK Fas-activated serine/threonine kinase
FBLN1 fibulin 1
FLJ11710 uncharacterized protein FLJ11710
FLJ42627 uncharacterized LOC645644
FN1 fibronectin 1
GABPB1 GA binding protein transcription factor, beta subunit 1
GAS8 growth arrest-specific 8
GDF11 growth differentiation factor 11
GLI3 GLI family zinc finger 3
GLRB glycine receptor, beta
GLRX glutaredoxin (thioltransferase)
GOSR2 golgi SNAP receptor complex member 2
GPC1 glypican 1
HIRIP3 HIRA interacting protein 3
HIST1H4J histone cluster 1, H4j
HN1L hematological and neurological expressed 1-like
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
KDM4B lysine (K)-specific demethylase 4B
LCN2 lipocalin 2
LGALS8 lectin, galactoside-binding, soluble, 8
LMBR1L limb development membrane protein 1-like
LPP LIM domain containing preferred translocation partner in lipoma
LRP5 low density lipoprotein receptor-related protein 5
LTBP1 latent transforming growth factor beta binding protein 1
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAGOHB mago-nashi homolog B (Drosophila)
MVK mevalonate kinase
MYOC myocilin, trabecular meshwork inducible glucocorticoid response
NADK NAD kinase
NCOA1 nuclear receptor coactivator 1
NIPSNAP3B nipsnap homolog 3B (C. elegans)
NOL6 nucleolar protein 6 (RNA-associated)
NOX1 NADPH oxidase 1
NUP205 nucleoporin 205kDa
OGFRL1 opioid growth factor receptor-like 1
OSBPL3 oxysterol binding protein-like 3
PAIP2B poly(A) binding protein interacting protein 2B
PCGF1 polycomb group ring finger 1
PDPK1 3-phosphoinositide dependent protein kinase 1
PLA2G2F phospholipase A2, group IIF
POLD4 polymerase (DNA-directed), delta 4, accessory subunit
POPDC3 popeye domain containing 3
POU5F1B POU class 5 homeobox 1B
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PRG3 proteoglycan 3
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
RAI14 retinoic acid induced 14
RECK reversion-inducing-cysteine-rich protein with kazal motifs
RPS11 ribosomal protein S11
RPS2 ribosomal protein S2
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
SHB Src homology 2 domain containing adaptor protein B
SIRT3 sirtuin 3
SLC13A3 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2
SLC25A17 solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SNX10 sorting nexin 10
SPRR3 small proline-rich protein 3
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
SUGP2 SURP and G patch domain containing 2
SYF2 SYF2 pre-mRNA-splicing factor
TICAM1 toll-like receptor adaptor molecule 1
TMEM187 transmembrane protein 187
TMEM70 transmembrane protein 70
TSPYL2 TSPY-like 2
TUBA4B tubulin, alpha 4b
TUBGCP3 tubulin, gamma complex associated protein 3
TXNRD2 thioredoxin reductase 2
UNC93B1 unc-93 homolog B1 (C. elegans)
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
VIPR1 vasoactive intestinal peptide receptor 1
VPS33B vacuolar protein sorting 33 homolog B (yeast)
ZNF292 zinc finger protein 292
ZNHIT2 zinc finger, HIT-type containing 2

decreased expression

Symbol Name
ADAM30 ADAM metallopeptidase domain 30
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
ADRA2B adrenoceptor alpha 2B
AMN amnion associated transmembrane protein
ASAP1-IT1 ASAP1 intronic transcript 1
C17ORF53 chromosome 17 open reading frame 53
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
C22ORF29 chromosome 22 open reading frame 29
CA6 carbonic anhydrase VI
CA9 carbonic anhydrase IX
CCL11 chemokine (C-C motif) ligand 11
CCL21 chemokine (C-C motif) ligand 21
CCR4 chemokine (C-C motif) receptor 4
CHRM5 cholinergic receptor, muscarinic 5
CLCN2 chloride channel, voltage-sensitive 2
CORO2A coronin, actin binding protein, 2A
CSN2 casein beta
CXORF21 chromosome X open reading frame 21
DEFA4 defensin, alpha 4, corticostatin
DRP2 dystrophin related protein 2
ECE2 endothelin converting enzyme 2
EVI2B ecotropic viral integration site 2B
FCGR1B Fc fragment of IgG, high affinity Ib, receptor (CD64)
FGF4 fibroblast growth factor 4
FGFBP1 fibroblast growth factor binding protein 1
GAGE3 G antigen 3
GAL3ST4 galactose-3-O-sulfotransferase 4
GPATCH1 G patch domain containing 1
GPX2 glutathione peroxidase 2
GRIP2 glutamate receptor interacting protein 2
GRPR gastrin-releasing peptide receptor
GUCA2A guanylate cyclase activator 2A (guanylin)
HAO1 hydroxyacid oxidase (glycolate oxidase) 1
HDHD3 haloacid dehalogenase-like hydrolase domain containing 3
HIST1H3J histone cluster 1, H3j
HOXB1 homeobox B1
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14
HSD17B3 hydroxysteroid (17-beta) dehydrogenase 3
HTR6 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled
IL22 interleukin 22
JAM3 junctional adhesion molecule 3
KCNC4 potassium channel, voltage gated Shaw related subfamily C, member 4
KIAA0509 uncharacterized LOC57242
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
KLRK1 killer cell lectin-like receptor subfamily K, member 1
KRT85 keratin 85, type II
L1TD1 LINE-1 type transposase domain containing 1
LOC100127972 uncharacterized LOC100127972
MEP1B meprin A, beta
MOB3B MOB kinase activator 3B
MPZ myelin protein zero
MYO1F myosin IF
NES nestin
NLRP2 NLR family, pyrin domain containing 2
NPPA natriuretic peptide A
NPTX1 neuronal pentraxin I
NRSN2 neurensin 2
NUPL2 nucleoporin like 2
OLFML2A olfactomedin-like 2A
OPRK1 opioid receptor, kappa 1
OR12D3 olfactory receptor, family 12, subfamily D, member 3
OR52A1 olfactory receptor, family 52, subfamily A, member 1
PAX1 paired box 1
PCBP4 poly(rC) binding protein 4
PDZK1IP1 PDZK1 interacting protein 1
PHOX2A paired-like homeobox 2a
PON3 paraoxonase 3
PQLC2 PQ loop repeat containing 2
PRAME preferentially expressed antigen in melanoma
PRDM14 PR domain containing 14
PRKCE protein kinase C, epsilon
RAB3A RAB3A, member RAS oncogene family
SIGLEC15 sialic acid binding Ig-like lectin 15
SLC31A2 solute carrier family 31 (copper transporter), member 2
SLC46A3 solute carrier family 46, member 3
SPATA20 spermatogenesis associated 20
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
SPON2 spondin 2, extracellular matrix protein
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
SSTR4 somatostatin receptor 4
STXBP5L syntaxin binding protein 5-like
SURF2 surfeit 2
TBC1D29 TBC1 domain family, member 29
TCP10L t-complex 10-like
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TMEM74B transmembrane protein 74B
TMPRSS5 transmembrane protease, serine 5
TNN tenascin N
TP53I3 tumor protein p53 inducible protein 3
TPM3 tropomyosin 3
TREML2 triggering receptor expressed on myeloid cells-like 2
TRPM2 transient receptor potential cation channel, subfamily M, member 2
TSHZ2 teashirt zinc finger homeobox 2
TSPAN1 tetraspanin 1
ZFR2 zinc finger RNA binding protein 2
ZKSCAN4 zinc finger with KRAB and SCAN domains 4
ZNF573 zinc finger protein 573
Funding