cobalt chloride-454 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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198 genes differentially expressed following the cobalt chloride-454 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AFF1 AF4/FMR2 family, member 1
ALCAM activated leukocyte cell adhesion molecule
ASCL1 achaete-scute family bHLH transcription factor 1
ATN1 atrophin 1
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
AXIN1 axin 1
C1ORF105 chromosome 1 open reading frame 105
CBX8 chromobox homolog 8
CCDC33 coiled-coil domain containing 33
CD82 CD82 molecule
CFAP70 cilia and flagella associated protein 70
CHI3L2 chitinase 3-like 2
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12
CNTFR ciliary neurotrophic factor receptor
COL18A1 collagen, type XVIII, alpha 1
COL5A3 collagen, type V, alpha 3
CRLF2 cytokine receptor-like factor 2
CRYM crystallin, mu
CSH2 chorionic somatomammotropin hormone 2
CSN2 casein beta
CXCR4 chemokine (C-X-C motif) receptor 4
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
CYTH1 cytohesin 1
DAXX death-domain associated protein
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4
DOK5 docking protein 5
DTX2 deltex 2, E3 ubiquitin ligase
ECE2 endothelin converting enzyme 2
ELAC2 elaC ribonuclease Z 2
ELF2 E74-like factor 2 (ets domain transcription factor)
FKBP10 FK506 binding protein 10, 65 kDa
FSCN3 fascin actin-bundling protein 3, testicular
GAS7 growth arrest-specific 7
GJB1 gap junction protein, beta 1, 32kDa
GOSR2 golgi SNAP receptor complex member 2
GP2 glycoprotein 2 (zymogen granule membrane)
GPR107 G protein-coupled receptor 107
GPR35 G protein-coupled receptor 35
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GUCA1A guanylate cyclase activator 1A (retina)
GYPC glycophorin C (Gerbich blood group)
HABP2 hyaluronan binding protein 2
HCP5 HLA complex P5 (non-protein coding)
HIRIP3 HIRA interacting protein 3
HK2 hexokinase 2
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IGFBP3 insulin-like growth factor binding protein 3
IGKV1D-13 immunoglobulin kappa variable 1D-13
IL15RA interleukin 15 receptor, alpha
ILK integrin-linked kinase
KRTAP1-1 keratin associated protein 1-1
LDLR low density lipoprotein receptor
LEMD3 LEM domain containing 3
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MBNL2 muscleblind-like splicing regulator 2
MST1 macrophage stimulating 1
MXD4 MAX dimerization protein 4
NCKAP1 NCK-associated protein 1
NCKAP1L NCK-associated protein 1-like
NDRG1 N-myc downstream regulated 1
NES nestin
NOV nephroblastoma overexpressed
NR2F1 nuclear receptor subfamily 2, group F, member 1
NXPH3 neurexophilin 3
OR10H3 olfactory receptor, family 10, subfamily H, member 3
OR1F1 olfactory receptor, family 1, subfamily F, member 1
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
PLGRKT plasminogen receptor, C-terminal lysine transmembrane protein
PNRC1 proline-rich nuclear receptor coactivator 1
POMT1 protein-O-mannosyltransferase 1
RAB27A RAB27A, member RAS oncogene family
RABL6 RAB, member RAS oncogene family-like 6
RNF220 ring finger protein 220
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2
SETD4 SET domain containing 4
SFTPC surfactant protein C
SGSH N-sulfoglucosamine sulfohydrolase
SH2B2 SH2B adaptor protein 2
SIGMAR1 sigma non-opioid intracellular receptor 1
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6
SLIT2 slit homolog 2 (Drosophila)
SZRD1 SUZ RNA binding domain containing 1
TCF7 transcription factor 7 (T-cell specific, HMG-box)
TCP11 t-complex 11, testis-specific
TCP11L1 t-complex 11, testis-specific-like 1
TGFA transforming growth factor, alpha
THBS4 thrombospondin 4
TMEM59L transmembrane protein 59-like
TP53I11 tumor protein p53 inducible protein 11
WDR48 WD repeat domain 48
ZNF287 zinc finger protein 287
ZNF93 zinc finger protein 93

decreased expression

Symbol Name
ADAP2 ArfGAP with dual PH domains 2
APITD1 apoptosis-inducing, TAF9-like domain 1
ARHGAP5 Rho GTPase activating protein 5
ARMC4 armadillo repeat containing 4
ARMC7 armadillo repeat containing 7
ASCC2 activating signal cointegrator 1 complex subunit 2
BCL10 B-cell CLL/lymphoma 10
C1ORF115 chromosome 1 open reading frame 115
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
CCDC94 coiled-coil domain containing 94
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin
CNTN1 contactin 1
COPG1 coatomer protein complex, subunit gamma 1
CTAGE9 CTAGE family, member 9
CXORF56 chromosome X open reading frame 56
CYB5R3 cytochrome b5 reductase 3
DAAM2 dishevelled associated activator of morphogenesis 2
DCP1A decapping mRNA 1A
DCSTAMP dendrocyte expressed seven transmembrane protein
DIO3 deiodinase, iodothyronine, type III
DNAI1 dynein, axonemal, intermediate chain 1
DSCAM Down syndrome cell adhesion molecule
ECM2 extracellular matrix protein 2, female organ and adipocyte specific
ELAVL4 ELAV like neuron-specific RNA binding protein 4
EVPL envoplakin
FAM114A2 family with sequence similarity 114, member A2
FGFBP1 fibroblast growth factor binding protein 1
GALT galactose-1-phosphate uridylyltransferase
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GMEB1 glucocorticoid modulatory element binding protein 1
GPRC5C G protein-coupled receptor, class C, group 5, member C
IFITM3 interferon induced transmembrane protein 3
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2
IGFBP6 insulin-like growth factor binding protein 6
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
JMJD4 jumonji domain containing 4
JOSD1 Josephin domain containing 1
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
KRT8P12 keratin 8 pseudogene 12
LACTB2 lactamase, beta 2
LAIR2 leukocyte-associated immunoglobulin-like receptor 2
LEFTY2 left-right determination factor 2
LIAS lipoic acid synthetase
LRRC42 leucine rich repeat containing 42
LUZP4 leucine zipper protein 4
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAGEH1 melanoma antigen family H1
MAML3 mastermind-like 3 (Drosophila)
MED23 mediator complex subunit 23
MGC2889 uncharacterized protein MGC2889
MRPL12 mitochondrial ribosomal protein L12
MYOC myocilin, trabecular meshwork inducible glucocorticoid response
N6AMT1 N-6 adenine-specific DNA methyltransferase 1 (putative)
NFE2L2 nuclear factor, erythroid 2-like 2
NUPL2 nucleoporin like 2
ODF2 outer dense fiber of sperm tails 2
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PAK1IP1 PAK1 interacting protein 1
PCDHB3 protocadherin beta 3
PIGH phosphatidylinositol glycan anchor biosynthesis, class H
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PLA2G12A phospholipase A2, group XIIA
PLCD1 phospholipase C, delta 1
PQLC3 PQ loop repeat containing 3
PRDM14 PR domain containing 14
PRMT3 protein arginine methyltransferase 3
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2
PSAT1 phosphoserine aminotransferase 1
RAB33B RAB33B, member RAS oncogene family
RASL10A RAS-like, family 10, member A
RORC RAR-related orphan receptor C
RUFY2 RUN and FYVE domain containing 2
RWDD2A RWD domain containing 2A
SCD5 stearoyl-CoA desaturase 5
SDC3 syndecan 3
SGPP1 sphingosine-1-phosphate phosphatase 1
SH2D4A SH2 domain containing 4A
SIL1 SIL1 nucleotide exchange factor
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SND1-IT1 SND1 intronic transcript 1
SQRDL sulfide quinone reductase-like (yeast)
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
STIM1 stromal interaction molecule 1
T T, brachyury homolog (mouse)
TET3 tet methylcytosine dioxygenase 3
TMEM127 transmembrane protein 127
TMEM53 transmembrane protein 53
TOLLIP toll interacting protein
TULP2 tubby like protein 2
TVP23B trans-golgi network vesicle protein 23 homolog B (S. cerevisiae)
VPS4B vacuolar protein sorting 4 homolog B (S. cerevisiae)
ZBTB39 zinc finger and BTB domain containing 39
ZCCHC6 zinc finger, CCHC domain containing 6
ZDHHC13 zinc finger, DHHC-type containing 13
ZNF394 zinc finger protein 394
ZNF408 zinc finger protein 408
ZNF652 zinc finger protein 652
ZNF668 zinc finger protein 668
ZNHIT2 zinc finger, HIT-type containing 2