cocaine dependence Gene Set

Dataset GWASdb SNP-Disease Associations
Category disease or phenotype associations
Type disease
Description A drug dependence that is a psychological dependency on the regular use of cocaine. (Human Disease Ontology, DOID_9975)
External Link http://jjwanglab.org/gwasdb/gwasdb2/gwasdb2/go_trait/DOID:9975
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Genes

47 genes associated with the disease cocaine dependence in GWAS and other genetic association datasets from the GWASdb SNP-Disease Associations dataset.

Symbol Name Standardized Value
FAM53B family with sequence similarity 53, member B 1.35834
NCOR2 nuclear receptor corepressor 2 1.24194
ANKRD31 ankyrin repeat domain 31 1.15242
CPE carboxypeptidase E 1.10977
CDK1 cyclin-dependent kinase 1 1.10764
RIMS2 regulating synaptic membrane exocytosis 2 1.10764
FERMT1 fermitin family member 1 1.10285
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2 1.09769
ZSWIM5 zinc finger, SWIM-type containing 5 1.09373
GCOM1 GRINL1A complex locus 1 1.09138
RNF43 ring finger protein 43 1.07539
C1QL2 complement component 1, q subcomponent-like 2 1.0459
CSMD3 CUB and Sushi multiple domains 3 0.986376
SCGB1D4 secretoglobin, family 1D, member 4 0.952622
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric 0.951514
LGR6 leucine-rich repeat containing G protein-coupled receptor 6 0.909246
STEAP3 STEAP family member 3, metalloreductase 0.890183
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 0.875673
LRRTM4 leucine rich repeat transmembrane neuronal 4 0.833585
AOAH acyloxyacyl hydrolase (neutrophil) 0.832379
FHOD3 formin homology 2 domain containing 3 0.826445
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1 0.810532
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 0.789545
ANK3 ankyrin 3, node of Ranvier (ankyrin G) 0.769617
CHST3 carbohydrate (chondroitin 6) sulfotransferase 3 0.760971
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 0.752915
FAM134B family with sequence similarity 134, member B 0.748856
GP6 glycoprotein VI (platelet) 0.690501
NCAM1 neural cell adhesion molecule 1 0.689711
ADGRE1 adhesion G protein-coupled receptor E1 0.687376
BPIFB4 BPI fold containing family B, member 4 0.685698
FAM107B family with sequence similarity 107, member B 0.684794
LINC01121 long intergenic non-protein coding RNA 1121 0.681401
DEPTOR DEP domain containing MTOR-interacting protein 0.64532
ZNRF1 zinc and ring finger 1, E3 ubiquitin protein ligase 0.64367
HDAC5 histone deacetylase 5 0.634612
HSF5 heat shock transcription factor family member 5 0.631427
VTI1A vesicle transport through interaction with t-SNAREs 1A 0.618094
RSU1 Ras suppressor protein 1 0.612357
VWF von Willebrand factor 0.611023
PIGB phosphatidylinositol glycan anchor biosynthesis, class B 0.604762
EHD4 EH-domain containing 4 0.59854
MTMR4 myotubularin related protein 4 0.588302
MBL2 mannose-binding lectin (protein C) 2, soluble 0.531357
POLR1A polymerase (RNA) I polypeptide A, 194kDa 0.520476
KRT73 keratin 73, type II 0.519368
ADRA1A adrenoceptor alpha 1A 0.512886