cognitive ability Gene Set

Dataset GAD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description The ability to learn and to deal with new situations and to deal effectively with tasks involving abstractions. (Experimental Factor Ontology, EFO_0004337)
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Genes

77 genes associated with the disease cognitive ability in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

Symbol Name
ADRA2A adrenoceptor alpha 2A
ADRA2C adrenoceptor alpha 2C
ALDH5A1 aldehyde dehydrogenase 5 family, member A1
APOE apolipoprotein E
BDNF brain-derived neurotrophic factor
BRAF B-Raf proto-oncogene, serine/threonine kinase
CLSTN2 calsyntenin 2
COMT catechol-O-methyltransferase
COX1
COX2
COX3
CRP C-reactive protein, pentraxin-related
CST3 cystatin C
CYP46A1 cytochrome P450, family 46, subfamily A, polypeptide 1
DAOA D-amino acid oxidase activator
DCLK1 doublecortin-like kinase 1
DISC1 disrupted in schizophrenia 1
DRD4 dopamine receptor D4
DRD5 dopamine receptor D5
DTNBP1 dystrobrevin binding protein 1
FMR1 fragile X mental retardation 1
GSTM1 glutathione S-transferase mu 1
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
HRAS Harvey rat sarcoma viral oncogene homolog
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1
HSPA8 heat shock 70kDa protein 8
HTT huntingtin
IL1B interleukin 1, beta
IL1RAPL1 interleukin 1 receptor accessory protein-like 1
KL klotho
KRAS Kirsten rat sarcoma viral oncogene homolog
LMNA lamin A/C
LRP1 low density lipoprotein receptor-related protein 1
LRP1B low density lipoprotein receptor-related protein 1B
MAP2K1 mitogen-activated protein kinase kinase 1
MAPT microtubule-associated protein tau
MMP9 matrix metallopeptidase 9
MT-ATP6 ATP synthase F0 subunit 6
MT-ATP8 ATP synthase F0 subunit 8
MT-CYB cytochrome b
MT-ND2 MTND2
MT-ND3 NADH dehydrogenase, subunit 3 (complex I)
MT-ND4 NADH dehydrogenase, subunit 4 (complex I)
MT-ND4L NADH dehydrogenase, subunit 4L (complex I)
MT-ND5 NADH dehydrogenase, subunit 5 (complex I)
MT-ND6 NADH dehydrogenase, subunit 6 (complex I)
MT-TG tRNA
MT-TL2 tRNA
MT-TQ tRNA
MT-TR tRNA
MT-TS2 tRNA
MT-TT tRNA
NCSTN nicastrin
ND1
NQO2 NAD(P)H dehydrogenase, quinone 2
NRXN1 neurexin 1
PPARG peroxisome proliferator-activated receptor gamma
PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B
PRNP prion protein
PTPN11 protein tyrosine phosphatase, non-receptor type 11
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
REST RE1-silencing transcription factor
RGS4 regulator of G-protein signaling 4
RNR1 RNA, ribosomal cluster 1
RNR2 RNA, ribosomal cluster 2
SHANK3 SH3 and multiple ankyrin repeat domains 3
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SOS1 son of sevenless homolog 1 (Drosophila)
TPH2 tryptophan hydroxylase 2
TRNE
TRS-AGA2-4 transfer RNA-Ser (AGA) 2-4
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
WRN Werner syndrome, RecQ helicase-like
WWC1 WW and C2 domain containing 1