colchicine-1598 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the colchicine-1598 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACVR1 activin A receptor, type I
ADARB1 adenosine deaminase, RNA-specific, B1
AKAP13 A kinase (PRKA) anchor protein 13
ANKRD12 ankyrin repeat domain 12
ANXA2 annexin A2
ARL4C ADP-ribosylation factor-like 4C
ARRB2 arrestin, beta 2
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1
ATXN1 ataxin 1
AXL AXL receptor tyrosine kinase
BCL3 B-cell CLL/lymphoma 3
BTG1 B-cell translocation gene 1, anti-proliferative
CAPN2 calpain 2, (m/II) large subunit
CAST calpastatin
CCL20 chemokine (C-C motif) ligand 20
CCNG2 cyclin G2
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CD58 CD58 molecule
CD83 CD83 molecule
CD86 CD86 molecule
CLDND1 claudin domain containing 1
CTSB cathepsin B
CYLD cylindromatosis (turban tumor syndrome)
DOCK4 dedicator of cytokinesis 4
DSE dermatan sulfate epimerase
DUSP4 dual specificity phosphatase 4
DUSP8 dual specificity phosphatase 8
ELF4 E74-like factor 4 (ets domain transcription factor)
EPB41L3 erythrocyte membrane protein band 4.1-like 3
FAM134B family with sequence similarity 134, member B
FAM13A family with sequence similarity 13, member A
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FTH1 ferritin, heavy polypeptide 1
FTH1P5 ferritin, heavy polypeptide 1 pseudogene 5
GAB2 GRB2-associated binding protein 2
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GLIPR1 GLI pathogenesis-related 1
GNG11 guanine nucleotide binding protein (G protein), gamma 11
GPR183 G protein-coupled receptor 183
HIST1H2BD histone cluster 1, H2bd
IER3 immediate early response 3
IFRD1 interferon-related developmental regulator 1
IL10RA interleukin 10 receptor, alpha
IL1RN interleukin 1 receptor antagonist
ISG20 interferon stimulated exonuclease gene 20kDa
JOSD1 Josephin domain containing 1
JUN jun proto-oncogene
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KIAA1109 KIAA1109
KLF2 Kruppel-like factor 2
KLF6 Kruppel-like factor 6
KLHL24 kelch-like family member 24
KYNU kynureninase
LITAF lipopolysaccharide-induced TNF factor
LPXN leupaxin
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MALT1 MALT1 paracaspase
MAPKBP1 mitogen-activated protein kinase binding protein 1
MARK4 MAP/microtubule affinity-regulating kinase 4
MICALL1 MICAL-like 1
MTRF1L mitochondrial translational release factor 1-like
NACAP1 nascent-polypeptide-associated complex alpha polypeptide pseudogene 1
NCOA3 nuclear receptor coactivator 3
NINJ1 ninjurin 1
NR4A1 nuclear receptor subfamily 4, group A, member 1
NR4A2 nuclear receptor subfamily 4, group A, member 2
NR4A3 nuclear receptor subfamily 4, group A, member 3
NT5E 5'-nucleotidase, ecto (CD73)
NTAN1 N-terminal asparagine amidase
OGFRL1 opioid growth factor receptor-like 1
PDE3B phosphodiesterase 3B, cGMP-inhibited
PDE4B phosphodiesterase 4B, cAMP-specific
PDLIM7 PDZ and LIM domain 7 (enigma)
PHLDA1 pleckstrin homology-like domain, family A, member 1
PLEKHO1 pleckstrin homology domain containing, family O member 1
PLSCR1 phospholipid scramblase 1
PNISR PNN-interacting serine/arginine-rich protein
POLD4 polymerase (DNA-directed), delta 4, accessory subunit
PPP1R16B protein phosphatase 1, regulatory subunit 16B
RAB31 RAB31, member RAS oncogene family
RAB8B RAB8B, member RAS oncogene family
RHOB ras homolog family member B
RIN3 Ras and Rab interactor 3
RIOK3 RIO kinase 3
RIT1 Ras-like without CAAX 1
RNF19B ring finger protein 19B
RP2 retinitis pigmentosa 2 (X-linked recessive)
SAP30L SAP30-like
SAT1 spermidine/spermine N1-acetyltransferase 1
SDC2 syndecan 2
SIPA1L1 signal-induced proliferation-associated 1 like 1
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10
SMAD7 SMAD family member 7
STK38L serine/threonine kinase 38 like
SWAP70 SWAP switching B-cell complex 70kDa subunit
TANK TRAF family member-associated NFKB activator
THBS1 thrombospondin 1
TPM4 tropomyosin 4
YPEL5 yippee-like 5 (Drosophila)

decreased expression

Symbol Name
ADCK3 aarF domain containing kinase 3
ADGRA3 adhesion G protein-coupled receptor A3
AHSA1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)
BRIX1 BRX1, biogenesis of ribosomes
BYSL bystin-like
C10ORF2 chromosome 10 open reading frame 2
C12ORF29 chromosome 12 open reading frame 29
C21ORF33 chromosome 21 open reading frame 33
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
CBR1 carbonyl reductase 1
CCL2 chemokine (C-C motif) ligand 2
CCL4 chemokine (C-C motif) ligand 4
CD302 CD302 molecule
CDK4 cyclin-dependent kinase 4
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12
CLUH clustered mitochondria (cluA/CLU1) homolog
COA4 cytochrome c oxidase assembly factor 4 homolog (S. cerevisiae)
COA7 cytochrome c oxidase assembly factor 7 (putative)
CTH cystathionine gamma-lyase
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
DEAF1 DEAF1 transcription factor
DLEU1 deleted in lymphocytic leukemia 1 (non-protein coding)
DLEU2 deleted in lymphocytic leukemia 2 (non-protein coding)
EBNA1BP2 EBNA1 binding protein 2
EIF2B3 eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
EMG1 EMG1 N1-specific pseudouridine methyltransferase
ERLIN1 ER lipid raft associated 1
ESF1 ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae)
FAM173A family with sequence similarity 173, member A
FAM208B family with sequence similarity 208, member B
FAM216A family with sequence similarity 216, member A
FAR2 fatty acyl CoA reductase 2
FARSA phenylalanyl-tRNA synthetase, alpha subunit
FLT3 fms-related tyrosine kinase 3
FPGT fucose-1-phosphate guanylyltransferase
GADD45A growth arrest and DNA-damage-inducible, alpha
GEMIN6 gem (nuclear organelle) associated protein 6
GNL3 guanine nucleotide binding protein-like 3 (nucleolar)
GOT1 glutamic-oxaloacetic transaminase 1, soluble
GPD1L glycerol-3-phosphate dehydrogenase 1-like
HSPE1 heat shock 10kDa protein 1
HSPH1 heat shock 105kDa/110kDa protein 1
IMPACT impact RWD domain protein
KBTBD11 kelch repeat and BTB (POZ) domain containing 11
KIAA0020 KIAA0020
MAK16 MAK16 homolog (S. cerevisiae)
MCM3AP-AS1 MCM3AP antisense RNA 1
MMACHC methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
MOSPD3 motile sperm domain containing 3
MRPL24 mitochondrial ribosomal protein L24
MRPS34 mitochondrial ribosomal protein S34
MRTO4 mRNA turnover 4 homolog (S. cerevisiae)
MYC v-myc avian myelocytomatosis viral oncogene homolog
NAT10 N-acetyltransferase 10 (GCN5-related)
NIP7 NIP7, nucleolar pre-rRNA processing protein
NOC2L nucleolar complex associated 2 homolog (S. cerevisiae)
NOC3L nucleolar complex associated 3 homolog (S. cerevisiae)
ODC1 ornithine decarboxylase 1
ORM1 orosomucoid 1
PDCD11 programmed cell death 11
PES1 pescadillo ribosomal biogenesis factor 1
PFAS phosphoribosylformylglycinamidine synthase
PHGDH phosphoglycerate dehydrogenase
PLAC8 placenta-specific 8
PNO1 partner of NOB1 homolog (S. cerevisiae)
POLR2F polymerase (RNA) II (DNA directed) polypeptide F
POLR3K polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa
PPAT phosphoribosyl pyrophosphate amidotransferase
PRDM13 PR domain containing 13
PRDX4 peroxiredoxin 4
PRTN3 proteinase 3
PSAT1 phosphoserine aminotransferase 1
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
PTRH2 peptidyl-tRNA hydrolase 2
PUS1 pseudouridylate synthase 1
PUS7 pseudouridylate synthase 7 (putative)
RPP40 ribonuclease P/MRP 40kDa subunit
RRP1 ribosomal RNA processing 1
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
RUVBL1 RuvB-like AAA ATPase 1
S100A9 S100 calcium binding protein A9
SEH1L SEH1-like (S. cerevisiae)
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5
SLC39A14 solute carrier family 39 (zinc transporter), member 14
SLIRP SRA stem-loop interacting RNA binding protein
SPP1 secreted phosphoprotein 1
SRM spermidine synthase
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
TRIB3 tribbles pseudokinase 3
TRMT11 tRNA methyltransferase 11 homolog (S. cerevisiae)
TTI2 TELO2 interacting protein 2
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
UCK2 uridine-cytidine kinase 2
UNG uracil-DNA glycosylase
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
WDR12 WD repeat domain 12
WDR3 WD repeat domain 3
WDR43 WD repeat domain 43