colchicine-3213 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the colchicine-3213 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACACB acetyl-CoA carboxylase beta
AFAP1 actin filament associated protein 1
ALDOB aldolase B, fructose-bisphosphate
ANGPTL2 angiopoietin-like 2
AP1S2 adaptor-related protein complex 1, sigma 2 subunit
AREG amphiregulin
ARID5A AT rich interactive domain 5A (MRF1-like)
ARMC4 armadillo repeat containing 4
ARTN artemin
ATN1 atrophin 1
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
BGLAP bone gamma-carboxyglutamate (gla) protein
BIRC3 baculoviral IAP repeat containing 3
BRD4 bromodomain containing 4
CDC42 cell division cycle 42
CHST10 carbohydrate sulfotransferase 10
CNOT3 CCR4-NOT transcription complex, subunit 3
COL4A2 collagen, type IV, alpha 2
COMP cartilage oligomeric matrix protein
CPNE7 copine VII
DGCR5 DiGeorge syndrome critical region gene 5 (non-protein coding)
DIO2 deiodinase, iodothyronine, type II
DMPK dystrophia myotonica-protein kinase
DPYSL4 dihydropyrimidinase-like 4
DSC2 desmocollin 2
DTNA dystrobrevin, alpha
EMP3 epithelial membrane protein 3
ERMAP erythroblast membrane-associated protein (Scianna blood group)
FAM106A family with sequence similarity 106, member A
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
FGFR4 fibroblast growth factor receptor 4
FOXO4 forkhead box O4
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
GADD45G growth arrest and DNA-damage-inducible, gamma
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
GLRA1 glycine receptor, alpha 1
GP2 glycoprotein 2 (zymogen granule membrane)
GRB10 growth factor receptor-bound protein 10
GSK3A glycogen synthase kinase 3 alpha
HDAC5 histone deacetylase 5
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
HOXA4 homeobox A4
IHH indian hedgehog
IRF8 interferon regulatory factor 8
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KCTD17 potassium channel tetramerization domain containing 17
KRT17 keratin 17, type I
LAMB4 laminin, beta 4
LIF leukemia inhibitory factor
LIMK1 LIM domain kinase 1
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
LPIN1 lipin 1
MFGE8 milk fat globule-EGF factor 8 protein
MIER2 mesoderm induction early response 1, family member 2
MST1 macrophage stimulating 1
MYO9B myosin IXB
NDST1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
NIN ninein (GSK3B interacting protein)
NOD1 nucleotide-binding oligomerization domain containing 1
OR10J1 olfactory receptor, family 10, subfamily J, member 1
PALM paralemmin
PCSK5 proprotein convertase subtilisin/kexin type 5
PEX26 peroxisomal biogenesis factor 26
PHF7 PHD finger protein 7
PHLDA1 pleckstrin homology-like domain, family A, member 1
PLG plasminogen
PPP1R9A protein phosphatase 1, regulatory subunit 9A
PRDM1 PR domain containing 1, with ZNF domain
PSD4 pleckstrin and Sec7 domain containing 4
PSG5 pregnancy specific beta-1-glycoprotein 5
RAB11B RAB11B, member RAS oncogene family
RALGPS1 Ral GEF with PH domain and SH3 binding motif 1
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RGS12 regulator of G-protein signaling 12
RUNX1 runt-related transcription factor 1
S100A2 S100 calcium binding protein A2
S100A9 S100 calcium binding protein A9
SAMD4A sterile alpha motif domain containing 4A
SCN2B sodium channel, voltage gated, type II beta subunit
SCUBE3 signal peptide, CUB domain, EGF-like 3
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
SERPINB13 serpin peptidase inhibitor, clade B (ovalbumin), member 13
SLMO1 slowmo homolog 1 (Drosophila)
SPATA1 spermatogenesis associated 1
SPEG SPEG complex locus
SPRY4 sprouty homolog 4 (Drosophila)
SRPK2 SRSF protein kinase 2
TAPT1 transmembrane anterior posterior transformation 1
TARP TCR gamma alternate reading frame protein
TEX14 testis expressed 14
TGFB2 transforming growth factor, beta 2
THNSL2 threonine synthase-like 2 (S. cerevisiae)
TLR2 toll-like receptor 2
TMEFF1 transmembrane protein with EGF-like and two follistatin-like domains 1
TMEM53 transmembrane protein 53
TRPC1 transient receptor potential cation channel, subfamily C, member 1
TULP1 tubby like protein 1
VCL vinculin
ZYX zyxin

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
AKAP12 A kinase (PRKA) anchor protein 12
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma
ARRB1 arrestin, beta 1
B3GNT1
BCAS1 breast carcinoma amplified sequence 1
BEX4 brain expressed, X-linked 4
BRIP1 BRCA1 interacting protein C-terminal helicase 1
BTF3P11 basic transcription factor 3 pseudogene 11
C11ORF63 chromosome 11 open reading frame 63
C17ORF80 chromosome 17 open reading frame 80
C21ORF91 chromosome 21 open reading frame 91
C22ORF46 chromosome 22 open reading frame 46
C2ORF54 chromosome 2 open reading frame 54
CBX8 chromobox homolog 8
CD83 CD83 molecule
CDON cell adhesion associated, oncogene regulated
CIDEB cell death-inducing DFFA-like effector b
CNGB3 cyclic nucleotide gated channel beta 3
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DMTN dematin actin binding protein
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DPY19L1P1 DPY19L1 pseudogene 1
EDAR ectodysplasin A receptor
EGFL7 EGF-like-domain, multiple 7
EXOC5 exocyst complex component 5
FKBP10 FK506 binding protein 10, 65 kDa
FOXN2 forkhead box N2
GAMT guanidinoacetate N-methyltransferase
GDAP1 ganglioside induced differentiation associated protein 1
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GPC3 glypican 3
GSTM2 glutathione S-transferase mu 2 (muscle)
HIST1H1C histone cluster 1, H1c
HIST1H1E histone cluster 1, H1e
HIST1H2AC histone cluster 1, H2ac
HIST1H2AK histone cluster 1, H2ak
HIST1H2AM histone cluster 1, H2am
HIST1H2BC histone cluster 1, H2bc
HIST1H2BM histone cluster 1, H2bm
HIST1H3H histone cluster 1, H3h
HIST1H4F histone cluster 1, H4f
HIST2H2BE histone cluster 2, H2be
HLA-J major histocompatibility complex, class I, J (pseudogene)
HOXA5 homeobox A5
HSPA1L heat shock 70kDa protein 1-like
INCENP inner centromere protein antigens 135/155kDa
IQSEC2 IQ motif and Sec7 domain 2
IRF9 interferon regulatory factor 9
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KIAA0125 KIAA0125
LARP6 La ribonucleoprotein domain family, member 6
LIG4 ligase IV, DNA, ATP-dependent
LINC00115 long intergenic non-protein coding RNA 115
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
LRRC37A2 leucine rich repeat containing 37, member A2
LZTFL1 leucine zipper transcription factor-like 1
MBTPS2 membrane-bound transcription factor peptidase, site 2
METTL16 methyltransferase like 16
NOL12 nucleolar protein 12
NPL N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)
NR1D2 nuclear receptor subfamily 1, group D, member 2
NUS1P3 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3
PCDHA6 protocadherin alpha 6
PDE12 phosphodiesterase 12
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PITX2 paired-like homeodomain 2
PLA2G10 phospholipase A2, group X
PLTP phospholipid transfer protein
POLL polymerase (DNA directed), lambda
PRAF2 PRA1 domain family, member 2
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RNF122 ring finger protein 122
RNF126P1 ring finger protein 126 pseudogene 1
RNF146 ring finger protein 146
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
SCPEP1 serine carboxypeptidase 1
SESN1 sestrin 1
SGPP1 sphingosine-1-phosphate phosphatase 1
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6
SLC12A8 solute carrier family 12, member 8
SMU1 smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans)
SPRY2 sprouty homolog 2 (Drosophila)
TCTN2 tectonic family member 2
TMEM104 transmembrane protein 104
TMEM120B transmembrane protein 120B
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TRAPPC13 trafficking protein particle complex 13
TTC30A tetratricopeptide repeat domain 30A
UNC93B1 unc-93 homolog B1 (C. elegans)
VEGFB vascular endothelial growth factor B
WLS wntless Wnt ligand secretion mediator
ZNF35 zinc finger protein 35
ZNF510 zinc finger protein 510