colchicine-4614 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the colchicine-4614 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAK1 AP2 associated kinase 1
ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9
ACSM3 acyl-CoA synthetase medium-chain family member 3
AIRE autoimmune regulator
AKAP12 A kinase (PRKA) anchor protein 12
ARHGAP26 Rho GTPase activating protein 26
ARTN artemin
ASCL1 achaete-scute family bHLH transcription factor 1
ATP10B ATPase, class V, type 10B
BMP1 bone morphogenetic protein 1
C1ORF116 chromosome 1 open reading frame 116
CACNA1G calcium channel, voltage-dependent, T type, alpha 1G subunit
CALCRL calcitonin receptor-like
CALD1 caldesmon 1
CARTPT CART prepropeptide
CCL13 chemokine (C-C motif) ligand 13
CD28 CD28 molecule
CNPY4 canopy FGF signaling regulator 4
COL2A1 collagen, type II, alpha 1
COL3A1 collagen, type III, alpha 1
CTAGE5 CTAGE family, member 5
CXCL8 chemokine (C-X-C motif) ligand 8
CYR61 cysteine-rich, angiogenic inducer, 61
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase)
DDN dendrin
DIMT1 DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae)
DOC2A double C2-like domains, alpha
DRP2 dystrophin related protein 2
DUSP1 dual specificity phosphatase 1
EED embryonic ectoderm development
EMC3 ER membrane protein complex subunit 3
EMID1 EMI domain containing 1
FAM134B family with sequence similarity 134, member B
FERMT2 fermitin family member 2
FGF20 fibroblast growth factor 20
FLT4 fms-related tyrosine kinase 4
FOXN3 forkhead box N3
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
FXYD2 FXYD domain containing ion transport regulator 2
HIC2 hypermethylated in cancer 2
HOXC4 homeobox C4
IGHM immunoglobulin heavy constant mu
IL11 interleukin 11
IL6 interleukin 6
JADE2 jade family PHD finger 2
JUN jun proto-oncogene
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KLHL23 kelch-like family member 23
KRT17 keratin 17, type I
KRT34 keratin 34, type I
LCAT lecithin-cholesterol acyltransferase
LTBP4 latent transforming growth factor beta binding protein 4
LY9 lymphocyte antigen 9
MGC12488
MMP28 matrix metallopeptidase 28
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MUC6 mucin 6, oligomeric mucus/gel-forming
NAV3 neuron navigator 3
NKX3-2 NK3 homeobox 2
NMUR1 neuromedin U receptor 1
NOL4 nucleolar protein 4
OR7E24 olfactory receptor, family 7, subfamily E, member 24
PCDHGA3 protocadherin gamma subfamily A, 3
PDCD2 programmed cell death 2
PDGFB platelet-derived growth factor beta polypeptide
PHLDB1 pleckstrin homology-like domain, family B, member 1
POM121L9P POM121 transmembrane nucleoporin-like 9, pseudogene
PRMT2 protein arginine methyltransferase 2
PRMT2IP PRMT2 interacting protein
PRSS21 protease, serine, 21 (testisin)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RABEP2 rabaptin, RAB GTPase binding effector protein 2
RAG2 recombination activating gene 2
RFXAP regulatory factor X-associated protein
RIC3 RIC3 acetylcholine receptor chaperone
RUNX1 runt-related transcription factor 1
S1PR1 sphingosine-1-phosphate receptor 1
SAMD4A sterile alpha motif domain containing 4A
SIDT2 SID1 transmembrane family, member 2
SLC22A7 solute carrier family 22 (organic anion transporter), member 7
SLC35F5 solute carrier family 35, member F5
SLMO1 slowmo homolog 1 (Drosophila)
SND1-IT1 SND1 intronic transcript 1
STOM stomatin
TAAR5 trace amine associated receptor 5
TGFB2 transforming growth factor, beta 2
THEMIS2 thymocyte selection associated family member 2
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TRD T cell receptor delta locus
TRIO trio Rho guanine nucleotide exchange factor
TRPC7 transient receptor potential cation channel, subfamily C, member 7
TSPY1 testis specific protein, Y-linked 1
TSSK2 testis-specific serine kinase 2
TUFT1 tuftelin 1
UGCG UDP-glucose ceramide glucosyltransferase
USF2 upstream transcription factor 2, c-fos interacting
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
WNT2B wingless-type MMTV integration site family, member 2B
WNT7A wingless-type MMTV integration site family, member 7A
ZBTB40 zinc finger and BTB domain containing 40

decreased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ABHD17B abhydrolase domain containing 17B
ADGRB2 adhesion G protein-coupled receptor B2
AMT aminomethyltransferase
ANKFY1 ankyrin repeat and FYVE domain containing 1
APH1B APH1B gamma secretase subunit
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
BDH1 3-hydroxybutyrate dehydrogenase, type 1
BFSP1 beaded filament structural protein 1, filensin
C19ORF40 chromosome 19 open reading frame 40
CCDC25 coiled-coil domain containing 25
CCDC69 coiled-coil domain containing 69
CDADC1 cytidine and dCMP deaminase domain containing 1
CDT1 chromatin licensing and DNA replication factor 1
CEP112 centrosomal protein 112kDa
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
CIR1 corepressor interacting with RBPJ, 1
CISH cytokine inducible SH2-containing protein
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
CNTLN centlein, centrosomal protein
CORO2A coronin, actin binding protein, 2A
CRYBB2P1 crystallin, beta B2 pseudogene 1
CUL9 cullin 9
CYP39A1 cytochrome P450, family 39, subfamily A, polypeptide 1
DARS2 aspartyl-tRNA synthetase 2, mitochondrial
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DNM3 dynamin 3
EN2 engrailed homeobox 2
ERAP2 endoplasmic reticulum aminopeptidase 2
ETNK2 ethanolamine kinase 2
FGF23 fibroblast growth factor 23
FOXRED2 FAD-dependent oxidoreductase domain containing 2
FZD8 frizzled class receptor 8
GLS2 glutaminase 2 (liver, mitochondrial)
GMPR guanosine monophosphate reductase
GTF2I general transcription factor IIi
H1F0 H1 histone family, member 0
HAS2 hyaluronan synthase 2
HIST1H2AG histone cluster 1, H2ag
HIST1H2AM histone cluster 1, H2am
HIST1H2BI histone cluster 1, H2bi
HMG20A high mobility group 20A
HOXA5 homeobox A5
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2
IFI6 interferon, alpha-inducible protein 6
IPP intracisternal A particle-promoted polypeptide
IQCG IQ motif containing G
KDM8 lysine (K)-specific demethylase 8
KLHL28 kelch-like family member 28
KLHL3 kelch-like family member 3
KRT20 keratin 20, type I
LOC730101 uncharacterized LOC730101
MCMBP minichromosome maintenance complex binding protein
MED18 mediator complex subunit 18
MFSD11 major facilitator superfamily domain containing 11
MOB3B MOB kinase activator 3B
MRPL44 mitochondrial ribosomal protein L44
MTERF4 mitochondrial transcription termination factor 4
MX1 MX dynamin-like GTPase 1
NDP Norrie disease (pseudoglioma)
OR1G1 olfactory receptor, family 1, subfamily G, member 1
PCOLCE procollagen C-endopeptidase enhancer
PHC1 polyhomeotic homolog 1 (Drosophila)
PIGL phosphatidylinositol glycan anchor biosynthesis, class L
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PPP1R3D protein phosphatase 1, regulatory subunit 3D
PRR7 proline rich 7 (synaptic)
PTGFR prostaglandin F receptor (FP)
RIBC2 RIB43A domain with coiled-coils 2
RRAGB Ras-related GTP binding B
SAMD9 sterile alpha motif domain containing 9
SAYSD1 SAYSVFN motif domain containing 1
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SPINK1 serine peptidase inhibitor, Kazal type 1
SSBP3 single stranded DNA binding protein 3
STAG3L4 stromal antigen 3-like 4 (pseudogene)
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
TBC1D8B TBC1 domain family, member 8B (with GRAM domain)
TBX19 T-box 19
TCTN2 tectonic family member 2
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
THBS3 thrombospondin 3
TRIM9 tripartite motif containing 9
TUBA1A tubulin, alpha 1a
TUBA4A tubulin, alpha 4a
TUBB tubulin, beta class I
TUBB2A tubulin, beta 2A class IIa
TUBB3 tubulin, beta 3 class III
TUBG2 tubulin, gamma 2
USP21 ubiquitin specific peptidase 21
WDR25 WD repeat domain 25
YEATS4 YEATS domain containing 4
YY2 YY2 transcription factor
ZNF227 zinc finger protein 227
ZNF230 zinc finger protein 230
ZNF276 zinc finger protein 276
ZNF606 zinc finger protein 606
ZNF747 zinc finger protein 747