colchicine-5675 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the colchicine-5675 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTG2 actin, gamma 2, smooth muscle, enteric
ADAMTSL4 ADAMTS-like 4
ADGRL3 adhesion G protein-coupled receptor L3
ADH1A alcohol dehydrogenase 1A (class I), alpha polypeptide
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
AMACR alpha-methylacyl-CoA racemase
AMPD3 adenosine monophosphate deaminase 3
ANGEL2 angel homolog 2 (Drosophila)
ANK1 ankyrin 1, erythrocytic
ANXA2P1 annexin A2 pseudogene 1
ATF3 activating transcription factor 3
ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
ATXN2L ataxin 2-like
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BET1L Bet1 golgi vesicular membrane trafficking protein-like
CARD10 caspase recruitment domain family, member 10
CCL27 chemokine (C-C motif) ligand 27
CCNJL cyclin J-like
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11
DFNB31 deafness, autosomal recessive 31
DSCAM Down syndrome cell adhesion molecule
DUSP10 dual specificity phosphatase 10
ECE1 endothelin converting enzyme 1
EDN1 endothelin 1
EGFR epidermal growth factor receptor
FAM110B family with sequence similarity 110, member B
FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
FGD1 FYVE, RhoGEF and PH domain containing 1
FSTL3 follistatin-like 3 (secreted glycoprotein)
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
FYB FYN binding protein
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GH1 growth hormone 1
GIMAP5 GTPase, IMAP family member 5
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GPR143 G protein-coupled receptor 143
GRM8 glutamate receptor, metabotropic 8
HEG1 heart development protein with EGF-like domains 1
HPCAL4 hippocalcin like 4
HRASLS HRAS-like suppressor
HSPA12A heat shock 70kDa protein 12A
ICOS inducible T-cell co-stimulator
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
INPP5B inositol polyphosphate-5-phosphatase, 75kDa
INSL5 insulin-like 5
ITM2A integral membrane protein 2A
JUN jun proto-oncogene
KLF6 Kruppel-like factor 6
KRT16 keratin 16, type I
KRT17 keratin 17, type I
LINC00302 long intergenic non-protein coding RNA 302
LMTK1 lemur tail kinase 1
LOC100131510 uncharacterized LOC100131510
LPIN1 lipin 1
LTBP4 latent transforming growth factor beta binding protein 4
MAPKBP1 mitogen-activated protein kinase binding protein 1
MBP myelin basic protein
METTL7A methyltransferase like 7A
MYO9B myosin IXB
MYT1L myelin transcription factor 1-like
NMT1 N-myristoyltransferase 1
NPAS2 neuronal PAS domain protein 2
NRSN2 neurensin 2
ONECUT2 one cut homeobox 2
PCLO piccolo presynaptic cytomatrix protein
POU2F2 POU class 2 homeobox 2
POU6F1 POU class 6 homeobox 1
PRKCQ protein kinase C, theta
PTP4A3 protein tyrosine phosphatase type IVA, member 3
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1
RUNX1 runt-related transcription factor 1
SAMD4A sterile alpha motif domain containing 4A
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2
SNTA1 syntrophin, alpha 1
SOCS7 suppressor of cytokine signaling 7
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
SYP synaptophysin
SYT2 synaptotagmin II
TBX5 T-box 5
TGFB2 transforming growth factor, beta 2
THBS3 thrombospondin 3
TIMP3 TIMP metallopeptidase inhibitor 3
TLDC1 TBC/LysM-associated domain containing 1
TLR2 toll-like receptor 2
TMLHE trimethyllysine hydroxylase, epsilon
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TRIM36 tripartite motif containing 36
VN1R1 vomeronasal 1 receptor 1
VNN2 vanin 2
ZCCHC14 zinc finger, CCHC domain containing 14
ZNF500 zinc finger protein 500
ZSCAN18 zinc finger and SCAN domain containing 18
ZYX zyxin
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1

decreased expression

Symbol Name
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ACVR2B activin A receptor, type IIB
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
ATF7IP2 activating transcription factor 7 interacting protein 2
ATP10D ATPase, class V, type 10D
BMP15 bone morphogenetic protein 15
BMP4 bone morphogenetic protein 4
BST2 bone marrow stromal cell antigen 2
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
C5ORF45 chromosome 5 open reading frame 45
CASS4 Cas scaffolding protein family member 4
CCDC121 coiled-coil domain containing 121
CD302 CD302 molecule
CDADC1 cytidine and dCMP deaminase domain containing 1
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DGAT1 diacylglycerol O-acyltransferase 1
DHRS3 dehydrogenase/reductase (SDR family) member 3
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DTX4 deltex 4, E3 ubiquitin ligase
EDAR ectodysplasin A receptor
ERCC4 excision repair cross-complementation group 4
FAM155A family with sequence similarity 155, member A
FOXA1 forkhead box A1
FOXRED2 FAD-dependent oxidoreductase domain containing 2
FRAT1 frequently rearranged in advanced T-cell lymphomas 1
FSD1 fibronectin type III and SPRY domain containing 1
GPR27 G protein-coupled receptor 27
GPRASP1 G protein-coupled receptor associated sorting protein 1
HCFC1 host cell factor C1
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HIST1H1E histone cluster 1, H1e
HIST1H2AK histone cluster 1, H2ak
HIST1H4D histone cluster 1, H4d
HOXA4 homeobox A4
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KIAA0894 KIAA0894 protein
LAX1 lymphocyte transmembrane adaptor 1
LINC00115 long intergenic non-protein coding RNA 115
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LOC730101 uncharacterized LOC730101
LONRF3 LON peptidase N-terminal domain and ring finger 3
LRRC37A3 leucine rich repeat containing 37, member A3
LRRC49 leucine rich repeat containing 49
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LTBP2 latent transforming growth factor beta binding protein 2
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
N4BP3 NEDD4 binding protein 3
NKX3-2 NK3 homeobox 2
NPIPB15 nuclear pore complex interacting protein family, member B15
NPIPB3 nuclear pore complex interacting protein family, member B3
NXPE3 neurexophilin and PC-esterase domain family, member 3
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
OVGP1 oviductal glycoprotein 1, 120kDa
PARP16 poly (ADP-ribose) polymerase family, member 16
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PDE8B phosphodiesterase 8B
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PIGN phosphatidylinositol glycan anchor biosynthesis, class N
POLH polymerase (DNA directed), eta
POM121 POM121 transmembrane nucleoporin
PRICKLE3 prickle homolog 3 (Drosophila)
PRSS16 protease, serine, 16 (thymus)
PTPRU protein tyrosine phosphatase, receptor type, U
RGS2 regulator of G-protein signaling 2
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
RUSC2 RUN and SH3 domain containing 2
SCG2 secretogranin II
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SLMO1 slowmo homolog 1 (Drosophila)
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SOX12 SRY (sex determining region Y)-box 12
SPINK5 serine peptidase inhibitor, Kazal type 5
SPRY2 sprouty homolog 2 (Drosophila)
TBR1 T-box, brain, 1
TGFBR3 transforming growth factor, beta receptor III
TH tyrosine hydroxylase
TIGD6 tigger transposable element derived 6
TMEM180 transmembrane protein 180
TMEM19 transmembrane protein 19
TMPRSS3 transmembrane protease, serine 3
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
ULBP2 UL16 binding protein 2
USP27X ubiquitin specific peptidase 27, X-linked
VIM vimentin
ZNF16 zinc finger protein 16
ZNF205 zinc finger protein 205
ZNF408 zinc finger protein 408
ZNF428 zinc finger protein 428
ZNF747 zinc finger protein 747
ZNF862 zinc finger protein 862