colchicine-644 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the colchicine-644 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACOT9 acyl-CoA thioesterase 9
APCS amyloid P component, serum
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ASB7 ankyrin repeat and SOCS box containing 7
ATN1 atrophin 1
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1
AVPR1B arginine vasopressin receptor 1B
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BCL7A B-cell CLL/lymphoma 7A
BICD1 bicaudal D homolog 1 (Drosophila)
BMP6 bone morphogenetic protein 6
C19ORF66 chromosome 19 open reading frame 66
C1ORF105 chromosome 1 open reading frame 105
CCDC7 coiled-coil domain containing 7
CCNL2 cyclin L2
CDH3 cadherin 3, type 1, P-cadherin (placental)
CDYL chromodomain protein, Y-like
CLDN15 claudin 15
DAGLA diacylglycerol lipase, alpha
DCLRE1A DNA cross-link repair 1A
EFNB3 ephrin-B3
EHD1 EH-domain containing 1
ELF4 E74-like factor 4 (ets domain transcription factor)
ELMO2 engulfment and cell motility 2
ERBB3 erb-b2 receptor tyrosine kinase 3
FBLN1 fibulin 1
FBXL7 F-box and leucine-rich repeat protein 7
FZD1 frizzled class receptor 1
GALR3 galanin receptor 3
GINS3 GINS complex subunit 3 (Psf3 homolog)
GLG1 golgi glycoprotein 1
GP2 glycoprotein 2 (zymogen granule membrane)
GRIP2 glutamate receptor interacting protein 2
GRK6 G protein-coupled receptor kinase 6
GRM4 glutamate receptor, metabotropic 4
GTF2F2 general transcription factor IIF, polypeptide 2, 30kDa
GYPB glycophorin B (MNS blood group)
HAB1 B1 for mucin
HCFC2 host cell factor C2
HNF1A HNF1 homeobox A
ICAM1 intercellular adhesion molecule 1
ICOSLG inducible T-cell co-stimulator ligand
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KLF15 Kruppel-like factor 15
LDLR low density lipoprotein receptor
LENEP lens epithelial protein
LGMN legumain
LINC00339 long intergenic non-protein coding RNA 339
LYN LYN proto-oncogene, Src family tyrosine kinase
MAP7D3 MAP7 domain containing 3
MARC1 mitochondrial amidoxime reducing component 1
MBD1 methyl-CpG binding domain protein 1
MFSD12 major facilitator superfamily domain containing 12
MMP25 matrix metallopeptidase 25
MNS1 meiosis-specific nuclear structural 1
MOB3B MOB kinase activator 3B
MPP2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
MRC2 mannose receptor, C type 2
MYL10 myosin, light chain 10, regulatory
NAP1L1 nucleosome assembly protein 1-like 1
NDC80 NDC80 kinetochore complex component
NDRG2 NDRG family member 2
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain)
NOP16 NOP16 nucleolar protein
OGFR opioid growth factor receptor
PECR peroxisomal trans-2-enoyl-CoA reductase
POLD1 polymerase (DNA directed), delta 1, catalytic subunit
POLG polymerase (DNA directed), gamma
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
RANBP3 RAN binding protein 3
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RBMS2 RNA binding motif, single stranded interacting protein 2
RIOK3 RIO kinase 3
RUNX1 runt-related transcription factor 1
SAMHD1 SAM domain and HD domain 1
SEC63 SEC63 homolog (S. cerevisiae)
SIRPA signal-regulatory protein alpha
SLC37A1 solute carrier family 37 (glucose-6-phosphate transporter), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SLCO2A1 solute carrier organic anion transporter family, member 2A1
SNX19 sorting nexin 19
STAT4 signal transducer and activator of transcription 4
TMEM127 transmembrane protein 127
TMEM57 transmembrane protein 57
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TXNL4A thioredoxin-like 4A
UBE2D1 ubiquitin-conjugating enzyme E2D 1
UBE2O ubiquitin-conjugating enzyme E2O
VIM vimentin
VIPR1 vasoactive intestinal peptide receptor 1
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae)
VRK3 vaccinia related kinase 3
ZFP36 ZFP36 ring finger protein
ZFP64 ZFP64 zinc finger protein
ZNF609 zinc finger protein 609

decreased expression

Symbol Name
ANXA2P3 annexin A2 pseudogene 3
ART1 ADP-ribosyltransferase 1
ASTE1 asteroid homolog 1 (Drosophila)
ATP11B ATPase, class VI, type 11B
ATXN8OS ATXN8 opposite strand (non-protein coding)
BCL10 B-cell CLL/lymphoma 10
BPIFA1 BPI fold containing family A, member 1
C17ORF80 chromosome 17 open reading frame 80
C7ORF43 chromosome 7 open reading frame 43
CAMKMT calmodulin-lysine N-methyltransferase
CCDC170 coiled-coil domain containing 170
CD3E CD3e molecule, epsilon (CD3-TCR complex)
CD53 CD53 molecule
CD80 CD80 molecule
CNTD2 cyclin N-terminal domain containing 2
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CRABP1 cellular retinoic acid binding protein 1
CROCCP2 ciliary rootlet coiled-coil, rootletin pseudogene 2
CST4 cystatin S
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DCP1A decapping mRNA 1A
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila)
DISC1 disrupted in schizophrenia 1
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24
ECE2 endothelin converting enzyme 2
ECHDC2 enoyl CoA hydratase domain containing 2
ERN2 endoplasmic reticulum to nucleus signaling 2
ESPN espin
FAM171A1 family with sequence similarity 171, member A1
FAM188A family with sequence similarity 188, member A
FRG1 FSHD region gene 1
FRMD1 FERM domain containing 1
GALK1 galactokinase 1
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial
GPX2 glutathione peroxidase 2
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
HOXA5 homeobox A5
HOXC4 homeobox C4
HS3ST2 heparan sulfate (glucosamine) 3-O-sulfotransferase 2
IL19 interleukin 19
IL1B interleukin 1, beta
INO80D INO80 complex subunit D
JMJD4 jumonji domain containing 4
JRKL JRK-like
KCNA6 potassium channel, voltage gated shaker related subfamily A, member 6
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KIF20B kinesin family member 20B
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
MAD2L1BP MAD2L1 binding protein
MAPK10 mitogen-activated protein kinase 10
MAPK3 mitogen-activated protein kinase 3
METTL8 methyltransferase like 8
MYL1 myosin, light chain 1, alkali; skeletal, fast
MYL12B myosin, light chain 12B, regulatory
NOX5 NADPH oxidase, EF-hand calcium binding domain 5
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OR12D2 olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene)
PADI1 peptidyl arginine deiminase, type I
PCDHB3 protocadherin beta 3
PCDHB6 protocadherin beta 6
PCDHGA1 protocadherin gamma subfamily A, 1
PCP4 Purkinje cell protein 4
PCSK7 proprotein convertase subtilisin/kexin type 7
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PRDM5 PR domain containing 5
QTRT1 queuine tRNA-ribosyltransferase 1
RAB33B RAB33B, member RAS oncogene family
RETSAT retinol saturase (all-trans-retinol 13,14-reductase)
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RLBP1 retinaldehyde binding protein 1
S1PR4 sphingosine-1-phosphate receptor 4
SCIN scinderin
SGK2 serum/glucocorticoid regulated kinase 2
SLC19A3 solute carrier family 19 (thiamine transporter), member 3
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
ST5 suppression of tumorigenicity 5
TCEA2 transcription elongation factor A (SII), 2
TMEM121 transmembrane protein 121
TRIM8 tripartite motif containing 8
TSNAXIP1 translin-associated factor X interacting protein 1
UNC93B1 unc-93 homolog B1 (C. elegans)
WDR19 WD repeat domain 19
XAB2 XPA binding protein 2
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZMAT3 zinc finger, matrin-type 3
ZNF180 zinc finger protein 180
ZNF264 zinc finger protein 264
ZNF266 zinc finger protein 266
ZNF446 zinc finger protein 446
ZNF557 zinc finger protein 557
ZNF652 zinc finger protein 652